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The map label for this gene is comK [H]

Identifier: 161509223

GI number: 161509223

Start: 1033014

End: 1033583

Strand: Reverse

Name: comK [H]

Synonym: USA300HOU_0983

Alternate gene names: 161509223

Gene position: 1033583-1033014 (Counterclockwise)

Preceding gene: 161509226

Following gene: 161509215

Centisome position: 35.98

GC content: 30.18

Gene sequence:

>570_bases
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
CGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTT
CATACCACAGTTTATGGCATCAATATAACAATTCCATTTTTTACTATTACATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Upstream 100 bases:

>100_bases
AATAACTTGACAACTCAGAATTTTATTATAAAATATCTTTATATCATTAATTGTATTTTTATATTAATGGTTTAAAACTT
AATAAAGCGAGGTTTTGCTT

Downstream 100 bases:

>100_bases
ATTGTTTATTTTTAAAATATGCGGAATGTTTTATAAATATAGTGTAAATGTTCTGCATATTTTTTTAAGGTATCTATTGC
AAATTAACTTAATCTTGTTA

Product: competence protein

Products: NA

Alternate protein names: CTF; Competence protein K [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Sequences:

>Translated_189_residues
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK
>Mature_189_residues
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Specific function: Intermediate regulatory gene required for the expression of the late competence genes comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes [H]

COG id: COG4903

COG function: function code K; Genetic competence transcription factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010461 [H]

Pfam domain/function: PF06338 ComK [H]

EC number: NA

Molecular weight: Translated: 22602; Mature: 22602

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTY
CCCCCEEEEEECCEEEECCCCCCCCCCCCCEEEECHHHCCCCHHHHHHHHHHHHHCCCCC
LGKKAETNRITGISSKPPILLTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCK
CCCCCCCCEEECCCCCCCEEEEECCCCEECCCCCCCCCCEEEEEEHHHHHHHHHHCCEEE
VTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMISKNPDQPIDYNKATLNVFEAL
EEEECCCEEEEEEHHHHHHHHHCCCEEEEEEECCCCHHHCCCCCCCCCCCHHHHHHHHHH
TRYSLFEDK
HHHHHCCCC
>Mature Secondary Structure
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTY
CCCCCEEEEEECCEEEECCCCCCCCCCCCCEEEECHHHCCCCHHHHHHHHHHHHHCCCCC
LGKKAETNRITGISSKPPILLTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCK
CCCCCCCCEEECCCCCCCEEEEECCCCEECCCCCCCCCCEEEEEEHHHHHHHHHHCCEEE
VTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMISKNPDQPIDYNKATLNVFEAL
EEEECCCEEEEEEHHHHHHHHHCCCEEEEEEECCCCHHHCCCCCCCCCCCHHHHHHHHHH
TRYSLFEDK
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8196543; 9579061; 9384377; 7783616; 11744713 [H]