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The map label for this gene is yacA

Identifier: 161486818

GI number: 161486818

Start: 159539

End: 160036

Strand: Direct

Name: yacA

Synonym: t0139

Alternate gene names: 161486818

Gene position: 159539-160036 (Clockwise)

Preceding gene: 29140679

Following gene: 29140681

Centisome position: 3.33

GC content: 57.83

Gene sequence:

>498_bases
GTGAGTGGAATACTGACGCGCTGGCGACAGTTAGGCAGACGATACTTCTGGCCGCATCTCTTATTAGGGATGGTCGCGGC
GAGTTTTGGTTTGCCCGCGCTCAGTAACGCCGCTGAAACCAATACGCCTGCAAGGACGACCGCCAGCACCGCGTCTAAAG
TTAACTTTAGCCATCTTGCGCTGTTAGAAGCCTCTAACCGTCGTCCCAATTTCACCGTAGATTACTGGCATCAGCACGCT
ATTCGCACGGTGATTCGCCACCTTTCTTTTGCAATGGCGCCGCAAACGCTGCCCGTTGCCGACGCGCCGTCGCCATTACA
GGCGCATCATATCGCCTTACTGAATACGCTCAGCGCGATGCTCACGCAGGAGGGCACGCCGCCGGCGATTGTTCGCCGCC
TCTCCCTGGCGTATTTTGCGCCACAAACCGCATTTAGCATCCCGGCCTGGATAAGTCAGGCGCAGGGTATCCGCGCCGGT
CCGCAACGTCTCAGCTAA

Upstream 100 bases:

>100_bases
TCGTCATTACTGCTGTAGCGCGTACGCTTTAATGATAAGATTTGTGCGCAAATTGTTTTGATTCCGTAAGCCCATGAGGG
GCATATCAGGTGGCAATGAC

Downstream 100 bases:

>100_bases
CGAAAAAAGACCCTTTTACTTTATTTGTAGCTCCGCGGCGCGGGGCATTTGAGACTTTATTATGCTAATCAAATTATTAA
CCAAAGTATTCGGTAGCCGT

Product: SecA regulator SecM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSGILTRWRQLGRRYFWPHLLLGMVAASFGLPALSNAAETNTPARTTASTASKVNFSHLALLEASNRRPNFTVDYWHQHA
IRTVIRHLSFAMAPQTLPVADAPSPLQAHHIALLNTLSAMLTQEGTPPAIVRRLSLAYFAPQTAFSIPAWISQAQGIRAG
PQRLS

Sequences:

>Translated_165_residues
MSGILTRWRQLGRRYFWPHLLLGMVAASFGLPALSNAAETNTPARTTASTASKVNFSHLALLEASNRRPNFTVDYWHQHA
IRTVIRHLSFAMAPQTLPVADAPSPLQAHHIALLNTLSAMLTQEGTPPAIVRRLSLAYFAPQTAFSIPAWISQAQGIRAG
PQRLS
>Mature_164_residues
SGILTRWRQLGRRYFWPHLLLGMVAASFGLPALSNAAETNTPARTTASTASKVNFSHLALLEASNRRPNFTVDYWHQHAI
RTVIRHLSFAMAPQTLPVADAPSPLQAHHIALLNTLSAMLTQEGTPPAIVRRLSLAYFAPQTAFSIPAWISQAQGIRAGP
QRLS

Specific function: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm, cytosol. Periplasm (By similarity). Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease (By similarity)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secM family

Homologues:

Organism=Escherichia coli, GI87081686, Length=170, Percent_Identity=72.9411764705882, Blast_Score=248, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECM_SALCH (Q57TC3)

Other databases:

- EMBL:   AE017220
- RefSeq:   YP_215119.1
- GeneID:   3332544
- GenomeReviews:   AE017220_GR
- KEGG:   sec:SC0132
- HOGENOM:   HBG416690
- OMA:   FAMAPQA
- ProtClustDB:   PRK02943
- BioCyc:   SENT321314:SCH_0132-MONOMER
- GO:   GO:0005829
- HAMAP:   MF_01332
- InterPro:   IPR009502
- PIRSF:   PIRSF004572
- ProDom:   PD089227

Pfam domain/function: PF06558 SecM

EC number: NA

Molecular weight: Translated: 18117; Mature: 17986

Theoretical pI: Translated: 12.16; Mature: 12.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGILTRWRQLGRRYFWPHLLLGMVAASFGLPALSNAAETNTPARTTASTASKVNFSHLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHH
LLEASNRRPNFTVDYWHQHAIRTVIRHLSFAMAPQTLPVADAPSPLQAHHIALLNTLSAM
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LTQEGTPPAIVRRLSLAYFAPQTAFSIPAWISQAQGIRAGPQRLS
HHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SGILTRWRQLGRRYFWPHLLLGMVAASFGLPALSNAAETNTPARTTASTASKVNFSHLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHH
LLEASNRRPNFTVDYWHQHAIRTVIRHLSFAMAPQTLPVADAPSPLQAHHIALLNTLSAM
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LTQEGTPPAIVRRLSLAYFAPQTAFSIPAWISQAQGIRAGPQRLS
HHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA