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The map label for this gene is lipB [H]

Identifier: 161486794

GI number: 161486794

Start: 2298379

End: 2299020

Strand: Direct

Name: lipB [H]

Synonym: t2232

Alternate gene names: 161486794

Gene position: 2298379-2299020 (Clockwise)

Preceding gene: 29142632

Following gene: 29142634

Centisome position: 47.96

GC content: 49.69

Gene sequence:

>642_bases
TTGTATCAGGATAAAATCCTTGTCCGCCAGCTCGGCCTTCAGCCCTATGAAGCTATCTCTCAGGCCATGCATAACTTTAC
CGATATGCGCGATGAAAACAGCCATGATGAAATCTGGTTGGTTGAGCATTACCCGGTGTTTACCCAGGGCCAGGCCGGTA
AAGCGGAACATATATTGATGCCTGGCGATATTCCCGTTGTGCAGAGCGATCGTGGAGGACAGGTGACCTATCATGGTCCG
GGCCAACAGGTAATGTACGTTTTACTTAACCTGAAACGACGTAAACTGGGCGTGCGTGATTTAGTCACCCTACTTGAACA
GACCGTGGTGAATACGCTGGCTGAAATGGGTATTGAGGCGCATCCGCGCGCCGATGCGCCGGGCGTCTACGTGGGTGAAA
AGAAAATCTGCTCGCTGGGTTTACGTATCCGTCGCGGCTGCTCATTCCACGGTTTAGCGCTAAACGTTAACATGGATCTT
TCTCCTTTCCTACGCATCAACCCGTGTGGTTATGCCGGCATGGAAATGGCTAAAATAACGCAGTGGAAGGAAGACGCTAC
CACAGATAATATTGCGCCCCGCTTGCTGGCGAATATTTTAGCTCTGCTAAATAATCCACCGTATGAATATATTGCTACTT
AA

Upstream 100 bases:

>100_bases
ATACATCCAGACGGTTACCCGGTCTTATCCGGGTAACTCCCCGCCTCCCCCGCTGTGATATACTTTCCTCTCTTTTTTCA
TTCTCTACGGAGATGCCGTT

Downstream 100 bases:

>100_bases
TGCGTAAAATATAATGGCCCAAGAAATTTATGGGTCATTAATCATATATGATTTGAATGCTTTACTTCTCCCCCCGCTTT
CTATATTTTCGTTATATCCC

Product: lipoate-protein ligase B

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MYQDKILVRQLGLQPYEAISQAMHNFTDMRDENSHDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVVQSDRGGQVTYHGP
GQQVMYVLLNLKRRKLGVRDLVTLLEQTVVNTLAEMGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDL
SPFLRINPCGYAGMEMAKITQWKEDATTDNIAPRLLANILALLNNPPYEYIAT

Sequences:

>Translated_213_residues
MYQDKILVRQLGLQPYEAISQAMHNFTDMRDENSHDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVVQSDRGGQVTYHGP
GQQVMYVLLNLKRRKLGVRDLVTLLEQTVVNTLAEMGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDL
SPFLRINPCGYAGMEMAKITQWKEDATTDNIAPRLLANILALLNNPPYEYIAT
>Mature_213_residues
MYQDKILVRQLGLQPYEAISQAMHNFTDMRDENSHDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVVQSDRGGQVTYHGP
GQQVMYVLLNLKRRKLGVRDLVTLLEQTVVNTLAEMGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDL
SPFLRINPCGYAGMEMAKITQWKEDATTDNIAPRLLANILALLNNPPYEYIAT

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG0321

COG function: function code H; Lipoate-protein ligase B

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipB family [H]

Homologues:

Organism=Homo sapiens, GI221554520, Length=132, Percent_Identity=35.6060606060606, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI87081767, Length=213, Percent_Identity=91.0798122065728, Blast_Score=409, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6323268, Length=152, Percent_Identity=34.8684210526316, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355483, Length=147, Percent_Identity=35.3741496598639, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 23886; Mature: 23886

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00092 N6_MTASE ; PS01313 LIPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQDKILVRQLGLQPYEAISQAMHNFTDMRDENSHDEIWLVEHYPVFTQGQAGKAEHILM
CCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCCCCCCCEEEE
PGDIPVVQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRDLVTLLEQTVVNTLAEMGIEA
CCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
HPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYAGMEMAKIT
CCCCCCCCEEECCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEECCCCCCCCHHHHHH
QWKEDATTDNIAPRLLANILALLNNPPYEYIAT
HHHCCCCCCCHHHHHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure
MYQDKILVRQLGLQPYEAISQAMHNFTDMRDENSHDEIWLVEHYPVFTQGQAGKAEHILM
CCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCCCCCCCEEEE
PGDIPVVQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRDLVTLLEQTVVNTLAEMGIEA
CCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
HPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYAGMEMAKIT
CCCCCCCCEEECCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEECCCCCCCCHHHHHH
QWKEDATTDNIAPRLLANILALLNNPPYEYIAT
HHHCCCCCCCHHHHHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA