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The map label for this gene is kgd [H]

Identifier: 161486720

GI number: 161486720

Start: 1173966

End: 1177631

Strand: Reverse

Name: kgd [H]

Synonym: cg1280

Alternate gene names: 161486720

Gene position: 1177631-1173966 (Counterclockwise)

Preceding gene: 62390020

Following gene: 62390018

Centisome position: 35.87

GC content: 59.0

Gene sequence:

>3666_bases
GTGAGCAGCGCTAGTACTTTCGGCCAGAATGCGTGGCTGGTAGACGAGATGTTCCAGCAGTTCCAGAAGGACCCCAAGTC
CGTGGACAAGGAATGGAGAGAACTCTTTGAGGCGCAGGGGGGACCAAATACTACCCCCGCTACAACAGAAGCACAGCCTT
CAGCGCCCAAGGAGTCTGCGAAACCAGCACCAAAGGCTGCCCCTGCAGCCAAGGCAGCACCGCGCGTAGAAACCAAGCCG
GCCGACAAGACCGCCCCTAAGGCCAAGGAGTCCTCAGTGCCACAGCAACCTAAGCTTCCGGAGCCAGGACAAACCCCAAT
CAGGGGTATTTTCAAGTCCATCGCGAAGAACATGGATATCTCCCTGGAAATCCCAACCGCAACCTCGGTTCGCGATATGC
CAGCTCGCCTCATGTTCGAAAACCGCGCGATGGTCAACGATCAGCTCAAGCGCACCCGCGGTGGCAAGATCTCCTTCACC
CACATCATTGGCTACGCCATGGTGAAGGCAGTCATGGCTCACCCGGACATGAACAACTCCTACGACGTCATCGACGGCAA
GCCAACCCTGATCGTGCCTGAGCACATCAACCTGGGCCTTGCTATCGACCTTCCTCAGAAGGACGGCTCCCGCGCACTTG
TCGTAGCAGCCATCAAGGAAACCGAGAAGATGAACTTCTCCGAGTTCCTCGCAGCCTACGAAGACATCGTGGCACGCTCC
CGCAAGGGCAAGCTCACCATGGATGACTACCAGGGCGTTACCGTTTCCTTGACCAACCCAGGTGGCATCGGTACCCGCCA
CTCTGTTCCACGTCTAACCAAGGGCCAGGGCACCATCATCGGTGTCGGTTCCATGGATTACCCAGCAGAGTTCCAGGGCG
CTTCAGAAGACCGCCTTGCAGAGCTCGGCGTTGGCAAACTTGTCACCATCACCTCCACCTACGATCACCGCGTGATCCAG
GGTGCTGTGTCCGGTGAATTCCTGCGCACCATGTCTCGCCTGCTCACCGATGATTCCTTCTGGGATGAGATCTTCGACGC
AATGAACGTTCCTTACACCCCAATGCGTTGGGCACAGGACGTTCCAAACACCGGTGTTGATAAGAACACCCGCGTCATGC
AGCTCATTGAGGCATACCGCTCCCGTGGACACCTCATCGCTGACACCAACCCACTTTCATGGGTTCAGCCTGGCATGCCA
GTTCCAGACCACCGCGACCTCGACATCGAGACCCACAACCTGACCATCTGGGATCTGGACCGTACCTTCAACGTCGGTGG
CTTCGGCGGCAAGGAGACCATGACCCTGCGCGAGGTACTGTCCCGCCTCCGCGCTGCGTACACCCTCAAGGTCGGCTCCG
AATACACCCACATCCTGGACCGCGACGAGCGCACCTGGCTGCAGGACCGCCTCGAGGCCGGAATGCCAAAGCCAACCCAG
GCAGAGCAGAAGTACATCCTGCAGAAGCTGAACGCCGCGGAGGCTTTCGAGAACTTCCTGCAGACCAAGTACGTCGGCCA
GAAGCGCTTCTCCCTCGAAGGTGCAGAAGCACTTATCCCACTGATGGACTCCGCCATCGACACCGCCGCAGGCCAAGGCC
TCGACGAAGTTGTCATCGGTATGCCACACCGTGGTCGCCTCAACGTGCTGTTCAACATCGTGGGCAAGCCACTGGCATCC
ATCTTCAACGAGTTTGAAGGCCAAATGGAGCAGGGCCAGATCGGTGGCTCCGGTGACGTGAAGTACCACCTCGGTTCCGA
AGGCCAGCACCTGCAGATGTTCGGCGACGGCGAGATCAAGGTCTCCCTGACTGCTAACCCGTCCCACCTGGAAGCTGTTA
ACCCAGTGATGGAAGGTATCGTCCGCGCAAAGCAGGACTACCTGGACAAGGGCGTAGACGGCAAGACTGTTGTGCCACTG
CTGCTCCACGGTGACGCTGCATTCGCAGGCCTGGGCATCGTGCCAGAAACCATCAACCTGGCTAAGCTGCGTGGCTACGA
CGTCGGCGGCACCATCCACATCGTGGTGAACAACCAGATCGGCTTCACCACCACCCCAGACTCCAGCCGCTCCATGCACT
ACGCAACCGACTACGCCAAGGCATTCGGCTGCCCAGTCTTCCACGTCAACGGCGACGACCCAGAGGCAGTTGTCTGGGTT
GGCCAGCTGGCCACCGAGTACCGTCGTCGCTTCGGCAAGGACGTCTTCATCGACCTCGTCTGCTACCGCCTCCGCGGCCA
CAACGAAGCTGATGATCCTTCCATGACCCAGCCAAAGATGTATGAGCTCATCACCGGCCGCGAGACCGTTCGTGCTCAGT
ACACCGAAGACCTGCTCGGACGTGGAGACCTCTCCAACGAAGATGCAGAAGCAGTCGTCCGCGACTTCCACGACCAGATG
GAATCTGTGTTCAACGAAGTCAAGGAAGGCGGCAAGAAGCAGGCTGAGGCACAGACCGGCATCACCGGCTCCCAGAAGCT
TCCACACGGCCTTGAGACCAACATCTCCCGTGAAGAGCTCCTGGAACTGGGACAGGCTTTCGCCAACACCCCAGAAGGCT
TCAACTACCACCCACGTGTGGCTCCCGTTGCTAAGAAGCGCGTCTCCTCTGTCACCGAAGGTGGCATCGACTGGGCATGG
GGCGAGCTCCTCGCCTTCGGTTCCCTGGCTAACTCCGGCCGCTTGGTTCGCCTTGCAGGTGAAGATTCCCGCCGCGGTAC
CTTCACCCAGCGCCACGCAGTTGCCATCGACCCAGCGACCGCTGAAGAGTTCAACCCACTCCACGAGCTTGCACAGTCCA
AGGGCAACAACGGTAAGTTCCTGGTCTACAACTCCGCACTGACCGAGTACGCAGGCATGGGCTTCGAGTACGGCTACTCC
GTAGGAAACGAAGACTCCATCGTTGCATGGGAAGCACAGTTCGGCGACTTCGCCAACGGCGCTCAGACCATCATCGATGA
GTACGTCTCCTCAGGCGAAGCTAAGTGGGGCCAGACCTCCAAGCTGATCCTTCTGCTGCCTCACGGCTACGAAGGCCAGG
GCCCAGACCACTCTTCCGCACGTATCGAGCGCTTCCTGCAGCTGTGCGCTGAGGGTTCCATGACTGTTGCTCAGCCATCC
ACCCCAGCAAACCACTTCCACCTACTGCGTCGTCACGCTCTGTCCGACCTGAAGCGTCCACTGGTTATCTTCACCCCGAA
GTCCATGCTGCGTAACAAGGCTGCTGCCTCCGCACCAGAAGACTTCACTGAGGTCACCAAGTTCCAGTCCGTGATCAACG
ATCCAAACGTTGCAGATGCAGCCAAGGTGAAGAAGGTCATGCTGGTCTCCGGCAAGCTGTACTACGAATTGGCAAAGCGC
AAGGAGAAGGACGGACGCGACGACATCGCGATCGTTCGTATCGAAATGCTCCACCCAATTCCGTTCAACCGCATCTCCGA
GGCTCTTGCCGGCTACCCTAACGCTGAGGAAGTCCTCTTCGTTCAGGATGAGCCAGCAAACCAGGGCCCATGGCCGTTCT
ACCAGGAGCACCTCCCAGAGCTGATCCCGAACATGCCAAAGATGCGCCGCGTTTCCCGCCGCGCTCAGTCCTCCACCGCA
ACTGGTGTTGCCAAGGTGCACCAGCTGGAGGAGAAGCAGCTTATCGACGAGGCTTTCGAGGCTTAA

Upstream 100 bases:

>100_bases
ACTGGGGCTTAGGCATAATCAGCCAACGACCAACGTTACAGTGGATAAAACAAAGCTCAATAAACCCTCAAGAAGCAAGG
AAAAGAGGCGAGTACCTGCC

Downstream 100 bases:

>100_bases
GTCTTTATAGTCCTGCACTAGCCTAGAAGGGCCTTATGCCGTGTGAATCACACAGCATACGGCCCTTTTTGCTGCCGTGG
TTGCCTAAGGTGGAAGGTAT

Product: alpha-ketoglutarate decarboxylase

Products: NA

Alternate protein names: Alpha-ketoglutarate dehydrogenase [H]

Number of amino acids: Translated: 1221; Mature: 1220

Protein sequence:

>1221_residues
MSSASTFGQNAWLVDEMFQQFQKDPKSVDKEWRELFEAQGGPNTTPATTEAQPSAPKESAKPAPKAAPAAKAAPRVETKP
ADKTAPKAKESSVPQQPKLPEPGQTPIRGIFKSIAKNMDISLEIPTATSVRDMPARLMFENRAMVNDQLKRTRGGKISFT
HIIGYAMVKAVMAHPDMNNSYDVIDGKPTLIVPEHINLGLAIDLPQKDGSRALVVAAIKETEKMNFSEFLAAYEDIVARS
RKGKLTMDDYQGVTVSLTNPGGIGTRHSVPRLTKGQGTIIGVGSMDYPAEFQGASEDRLAELGVGKLVTITSTYDHRVIQ
GAVSGEFLRTMSRLLTDDSFWDEIFDAMNVPYTPMRWAQDVPNTGVDKNTRVMQLIEAYRSRGHLIADTNPLSWVQPGMP
VPDHRDLDIETHNLTIWDLDRTFNVGGFGGKETMTLREVLSRLRAAYTLKVGSEYTHILDRDERTWLQDRLEAGMPKPTQ
AEQKYILQKLNAAEAFENFLQTKYVGQKRFSLEGAEALIPLMDSAIDTAAGQGLDEVVIGMPHRGRLNVLFNIVGKPLAS
IFNEFEGQMEQGQIGGSGDVKYHLGSEGQHLQMFGDGEIKVSLTANPSHLEAVNPVMEGIVRAKQDYLDKGVDGKTVVPL
LLHGDAAFAGLGIVPETINLAKLRGYDVGGTIHIVVNNQIGFTTTPDSSRSMHYATDYAKAFGCPVFHVNGDDPEAVVWV
GQLATEYRRRFGKDVFIDLVCYRLRGHNEADDPSMTQPKMYELITGRETVRAQYTEDLLGRGDLSNEDAEAVVRDFHDQM
ESVFNEVKEGGKKQAEAQTGITGSQKLPHGLETNISREELLELGQAFANTPEGFNYHPRVAPVAKKRVSSVTEGGIDWAW
GELLAFGSLANSGRLVRLAGEDSRRGTFTQRHAVAIDPATAEEFNPLHELAQSKGNNGKFLVYNSALTEYAGMGFEYGYS
VGNEDSIVAWEAQFGDFANGAQTIIDEYVSSGEAKWGQTSKLILLLPHGYEGQGPDHSSARIERFLQLCAEGSMTVAQPS
TPANHFHLLRRHALSDLKRPLVIFTPKSMLRNKAAASAPEDFTEVTKFQSVINDPNVADAAKVKKVMLVSGKLYYELAKR
KEKDGRDDIAIVRIEMLHPIPFNRISEALAGYPNAEEVLFVQDEPANQGPWPFYQEHLPELIPNMPKMRRVSRRAQSSTA
TGVAKVHQLEEKQLIDEAFEA

Sequences:

>Translated_1221_residues
MSSASTFGQNAWLVDEMFQQFQKDPKSVDKEWRELFEAQGGPNTTPATTEAQPSAPKESAKPAPKAAPAAKAAPRVETKP
ADKTAPKAKESSVPQQPKLPEPGQTPIRGIFKSIAKNMDISLEIPTATSVRDMPARLMFENRAMVNDQLKRTRGGKISFT
HIIGYAMVKAVMAHPDMNNSYDVIDGKPTLIVPEHINLGLAIDLPQKDGSRALVVAAIKETEKMNFSEFLAAYEDIVARS
RKGKLTMDDYQGVTVSLTNPGGIGTRHSVPRLTKGQGTIIGVGSMDYPAEFQGASEDRLAELGVGKLVTITSTYDHRVIQ
GAVSGEFLRTMSRLLTDDSFWDEIFDAMNVPYTPMRWAQDVPNTGVDKNTRVMQLIEAYRSRGHLIADTNPLSWVQPGMP
VPDHRDLDIETHNLTIWDLDRTFNVGGFGGKETMTLREVLSRLRAAYTLKVGSEYTHILDRDERTWLQDRLEAGMPKPTQ
AEQKYILQKLNAAEAFENFLQTKYVGQKRFSLEGAEALIPLMDSAIDTAAGQGLDEVVIGMPHRGRLNVLFNIVGKPLAS
IFNEFEGQMEQGQIGGSGDVKYHLGSEGQHLQMFGDGEIKVSLTANPSHLEAVNPVMEGIVRAKQDYLDKGVDGKTVVPL
LLHGDAAFAGLGIVPETINLAKLRGYDVGGTIHIVVNNQIGFTTTPDSSRSMHYATDYAKAFGCPVFHVNGDDPEAVVWV
GQLATEYRRRFGKDVFIDLVCYRLRGHNEADDPSMTQPKMYELITGRETVRAQYTEDLLGRGDLSNEDAEAVVRDFHDQM
ESVFNEVKEGGKKQAEAQTGITGSQKLPHGLETNISREELLELGQAFANTPEGFNYHPRVAPVAKKRVSSVTEGGIDWAW
GELLAFGSLANSGRLVRLAGEDSRRGTFTQRHAVAIDPATAEEFNPLHELAQSKGNNGKFLVYNSALTEYAGMGFEYGYS
VGNEDSIVAWEAQFGDFANGAQTIIDEYVSSGEAKWGQTSKLILLLPHGYEGQGPDHSSARIERFLQLCAEGSMTVAQPS
TPANHFHLLRRHALSDLKRPLVIFTPKSMLRNKAAASAPEDFTEVTKFQSVINDPNVADAAKVKKVMLVSGKLYYELAKR
KEKDGRDDIAIVRIEMLHPIPFNRISEALAGYPNAEEVLFVQDEPANQGPWPFYQEHLPELIPNMPKMRRVSRRAQSSTA
TGVAKVHQLEEKQLIDEAFEA
>Mature_1220_residues
SSASTFGQNAWLVDEMFQQFQKDPKSVDKEWRELFEAQGGPNTTPATTEAQPSAPKESAKPAPKAAPAAKAAPRVETKPA
DKTAPKAKESSVPQQPKLPEPGQTPIRGIFKSIAKNMDISLEIPTATSVRDMPARLMFENRAMVNDQLKRTRGGKISFTH
IIGYAMVKAVMAHPDMNNSYDVIDGKPTLIVPEHINLGLAIDLPQKDGSRALVVAAIKETEKMNFSEFLAAYEDIVARSR
KGKLTMDDYQGVTVSLTNPGGIGTRHSVPRLTKGQGTIIGVGSMDYPAEFQGASEDRLAELGVGKLVTITSTYDHRVIQG
AVSGEFLRTMSRLLTDDSFWDEIFDAMNVPYTPMRWAQDVPNTGVDKNTRVMQLIEAYRSRGHLIADTNPLSWVQPGMPV
PDHRDLDIETHNLTIWDLDRTFNVGGFGGKETMTLREVLSRLRAAYTLKVGSEYTHILDRDERTWLQDRLEAGMPKPTQA
EQKYILQKLNAAEAFENFLQTKYVGQKRFSLEGAEALIPLMDSAIDTAAGQGLDEVVIGMPHRGRLNVLFNIVGKPLASI
FNEFEGQMEQGQIGGSGDVKYHLGSEGQHLQMFGDGEIKVSLTANPSHLEAVNPVMEGIVRAKQDYLDKGVDGKTVVPLL
LHGDAAFAGLGIVPETINLAKLRGYDVGGTIHIVVNNQIGFTTTPDSSRSMHYATDYAKAFGCPVFHVNGDDPEAVVWVG
QLATEYRRRFGKDVFIDLVCYRLRGHNEADDPSMTQPKMYELITGRETVRAQYTEDLLGRGDLSNEDAEAVVRDFHDQME
SVFNEVKEGGKKQAEAQTGITGSQKLPHGLETNISREELLELGQAFANTPEGFNYHPRVAPVAKKRVSSVTEGGIDWAWG
ELLAFGSLANSGRLVRLAGEDSRRGTFTQRHAVAIDPATAEEFNPLHELAQSKGNNGKFLVYNSALTEYAGMGFEYGYSV
GNEDSIVAWEAQFGDFANGAQTIIDEYVSSGEAKWGQTSKLILLLPHGYEGQGPDHSSARIERFLQLCAEGSMTVAQPST
PANHFHLLRRHALSDLKRPLVIFTPKSMLRNKAAASAPEDFTEVTKFQSVINDPNVADAAKVKKVMLVSGKLYYELAKRK
EKDGRDDIAIVRIEMLHPIPFNRISEALAGYPNAEEVLFVQDEPANQGPWPFYQEHLPELIPNMPKMRRVSRRAQSSTAT
GVAKVHQLEEKQLIDEAFEA

Specific function: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components:2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2)

COG id: COG0567

COG function: function code C; 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha-ketoglutarate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI51873036, Length=901, Percent_Identity=39.0677025527192, Blast_Score=625, Evalue=1e-179,
Organism=Homo sapiens, GI259013553, Length=902, Percent_Identity=39.1352549889135, Blast_Score=623, Evalue=1e-178,
Organism=Homo sapiens, GI221316661, Length=899, Percent_Identity=38.0422691879866, Blast_Score=608, Evalue=1e-173,
Organism=Homo sapiens, GI221316665, Length=887, Percent_Identity=37.880496054115, Blast_Score=598, Evalue=1e-171,
Organism=Homo sapiens, GI221316669, Length=798, Percent_Identity=38.9724310776942, Blast_Score=568, Evalue=1e-161,
Organism=Homo sapiens, GI38788380, Length=876, Percent_Identity=36.6438356164384, Blast_Score=545, Evalue=1e-155,
Organism=Homo sapiens, GI51873038, Length=284, Percent_Identity=39.0845070422535, Blast_Score=196, Evalue=1e-49,
Organism=Homo sapiens, GI19923748, Length=199, Percent_Identity=26.6331658291457, Blast_Score=71, Evalue=7e-12,
Organism=Escherichia coli, GI1786945, Length=866, Percent_Identity=44.4572748267898, Blast_Score=713, Evalue=0.0,
Organism=Escherichia coli, GI1786946, Length=211, Percent_Identity=23.696682464455, Blast_Score=71, Evalue=4e-13,
Organism=Escherichia coli, GI1786305, Length=188, Percent_Identity=29.2553191489362, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17542494, Length=900, Percent_Identity=40.8888888888889, Blast_Score=654, Evalue=0.0,
Organism=Caenorhabditis elegans, GI72001668, Length=880, Percent_Identity=36.5909090909091, Blast_Score=545, Evalue=1e-155,
Organism=Saccharomyces cerevisiae, GI6322066, Length=952, Percent_Identity=39.4957983193277, Blast_Score=657, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320352, Length=322, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24665669, Length=892, Percent_Identity=39.6860986547085, Blast_Score=627, Evalue=1e-179,
Organism=Drosophila melanogaster, GI24665673, Length=892, Percent_Identity=39.6860986547085, Blast_Score=627, Evalue=1e-179,
Organism=Drosophila melanogaster, GI24665677, Length=892, Percent_Identity=39.6860986547085, Blast_Score=627, Evalue=1e-179,
Organism=Drosophila melanogaster, GI28574592, Length=892, Percent_Identity=39.6860986547085, Blast_Score=627, Evalue=1e-179,
Organism=Drosophila melanogaster, GI28574590, Length=903, Percent_Identity=39.4241417497231, Blast_Score=626, Evalue=1e-179,
Organism=Drosophila melanogaster, GI161084450, Length=903, Percent_Identity=39.4241417497231, Blast_Score=626, Evalue=1e-179,
Organism=Drosophila melanogaster, GI161084461, Length=867, Percent_Identity=40.0230680507497, Blast_Score=617, Evalue=1e-176,
Organism=Drosophila melanogaster, GI281365454, Length=903, Percent_Identity=38.6489479512735, Blast_Score=600, Evalue=1e-171,
Organism=Drosophila melanogaster, GI281365452, Length=903, Percent_Identity=38.6489479512735, Blast_Score=600, Evalue=1e-171,
Organism=Drosophila melanogaster, GI78706592, Length=903, Percent_Identity=38.6489479512735, Blast_Score=600, Evalue=1e-171,
Organism=Drosophila melanogaster, GI78706596, Length=903, Percent_Identity=38.6489479512735, Blast_Score=600, Evalue=1e-171,
Organism=Drosophila melanogaster, GI78706594, Length=924, Percent_Identity=37.6623376623377, Blast_Score=587, Evalue=1e-167,
Organism=Drosophila melanogaster, GI78706598, Length=924, Percent_Identity=37.6623376623377, Blast_Score=587, Evalue=1e-167,
Organism=Drosophila melanogaster, GI24651589, Length=904, Percent_Identity=36.5044247787611, Blast_Score=540, Evalue=1e-153,
Organism=Drosophila melanogaster, GI161079314, Length=747, Percent_Identity=39.4912985274431, Blast_Score=511, Evalue=1e-144,
Organism=Drosophila melanogaster, GI24651591, Length=747, Percent_Identity=39.4912985274431, Blast_Score=511, Evalue=1e-144,
Organism=Drosophila melanogaster, GI24645909, Length=201, Percent_Identity=26.865671641791, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001078
- InterPro:   IPR011603
- InterPro:   IPR023213
- InterPro:   IPR001017
- InterPro:   IPR005475 [H]

Pfam domain/function: PF00198 2-oxoacid_dh; PF00676 E1_dh; PF02779 Transket_pyr [H]

EC number: =1.2.4.2 [H]

Molecular weight: Translated: 134666; Mature: 134535

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSASTFGQNAWLVDEMFQQFQKDPKSVDKEWRELFEAQGGPNTTPATTEAQPSAPKESA
CCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
KPAPKAAPAAKAAPRVETKPADKTAPKAKESSVPQQPKLPEPGQTPIRGIFKSIAKNMDI
CCCCCCCCCHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCE
SLEIPTATSVRDMPARLMFENRAMVNDQLKRTRGGKISFTHIIGYAMVKAVMAHPDMNNS
EEECCCCCCCHHCCHHHHHHCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCC
YDVIDGKPTLIVPEHINLGLAIDLPQKDGSRALVVAAIKETEKMNFSEFLAAYEDIVARS
EEEECCCCCEEECCCCCEEEEEECCCCCCCCEEEEEEEHHHHCCCHHHHHHHHHHHHHHC
RKGKLTMDDYQGVTVSLTNPGGIGTRHSVPRLTKGQGTIIGVGSMDYPAEFQGASEDRLA
CCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHCCCCCHHHHH
ELGVGKLVTITSTYDHRVIQGAVSGEFLRTMSRLLTDDSFWDEIFDAMNVPYTPMRWAQD
HCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHC
VPNTGVDKNTRVMQLIEAYRSRGHLIADTNPLSWVQPGMPVPDHRDLDIETHNLTIWDLD
CCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEECEEEEEECC
RTFNVGGFGGKETMTLREVLSRLRAAYTLKVGSEYTHILDRDERTWLQDRLEAGMPKPTQ
CEECCCCCCCCHHHHHHHHHHHHHHHEEEEECCHHHHHHCCCHHHHHHHHHHCCCCCCCH
AEQKYILQKLNAAEAFENFLQTKYVGQKRFSLEGAEALIPLMDSAIDTAAGQGLDEVVIG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCC
MPHRGRLNVLFNIVGKPLASIFNEFEGQMEQGQIGGSGDVKYHLGSEGQHLQMFGDGEIK
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCEEEEECCCCCEEEEEECCEEE
VSLTANPSHLEAVNPVMEGIVRAKQDYLDKGVDGKTVVPLLLHGDAAFAGLGIVPETINL
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHCCCCCCCCCCH
AKLRGYDVGGTIHIVVNNQIGFTTTPDSSRSMHYATDYAKAFGCPVFHVNGDDPEAVVWV
HHCCCCCCCCEEEEEEECCCCCEECCCCCCCEEHHHHHHHHHCCCEEEECCCCCCEEEEH
GQLATEYRRRFGKDVFIDLVCYRLRGHNEADDPSMTQPKMYELITGRETVRAQYTEDLLG
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHC
RGDLSNEDAEAVVRDFHDQMESVFNEVKEGGKKQAEAQTGITGSQKLPHGLETNISREEL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
LELGQAFANTPEGFNYHPRVAPVAKKRVSSVTEGGIDWAWGELLAFGSLANSGRLVRLAG
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEC
EDSRRGTFTQRHAVAIDPATAEEFNPLHELAQSKGNNGKFLVYNSALTEYAGMGFEYGYS
CCCCCCCCCCCCEEEECCCCHHHCCHHHHHHHCCCCCCCEEEECCHHHHHHCCCCCCCCC
VGNEDSIVAWEAQFGDFANGAQTIIDEYVSSGEAKWGQTSKLILLLPHGYEGQGPDHSSA
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCHHH
RIERFLQLCAEGSMTVAQPSTPANHFHLLRRHALSDLKRPLVIFTPKSMLRNKAAASAPE
HHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHCCCCH
DFTEVTKFQSVINDPNVADAAKVKKVMLVSGKLYYELAKRKEKDGRDDIAIVRIEMLHPI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEEEECCC
PFNRISEALAGYPNAEEVLFVQDEPANQGPWPFYQEHLPELIPNMPKMRRVSRRAQSSTA
CHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TGVAKVHQLEEKQLIDEAFEA
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSASTFGQNAWLVDEMFQQFQKDPKSVDKEWRELFEAQGGPNTTPATTEAQPSAPKESA
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
KPAPKAAPAAKAAPRVETKPADKTAPKAKESSVPQQPKLPEPGQTPIRGIFKSIAKNMDI
CCCCCCCCCHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCE
SLEIPTATSVRDMPARLMFENRAMVNDQLKRTRGGKISFTHIIGYAMVKAVMAHPDMNNS
EEECCCCCCCHHCCHHHHHHCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCC
YDVIDGKPTLIVPEHINLGLAIDLPQKDGSRALVVAAIKETEKMNFSEFLAAYEDIVARS
EEEECCCCCEEECCCCCEEEEEECCCCCCCCEEEEEEEHHHHCCCHHHHHHHHHHHHHHC
RKGKLTMDDYQGVTVSLTNPGGIGTRHSVPRLTKGQGTIIGVGSMDYPAEFQGASEDRLA
CCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHCCCCCHHHHH
ELGVGKLVTITSTYDHRVIQGAVSGEFLRTMSRLLTDDSFWDEIFDAMNVPYTPMRWAQD
HCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHC
VPNTGVDKNTRVMQLIEAYRSRGHLIADTNPLSWVQPGMPVPDHRDLDIETHNLTIWDLD
CCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEECEEEEEECC
RTFNVGGFGGKETMTLREVLSRLRAAYTLKVGSEYTHILDRDERTWLQDRLEAGMPKPTQ
CEECCCCCCCCHHHHHHHHHHHHHHHEEEEECCHHHHHHCCCHHHHHHHHHHCCCCCCCH
AEQKYILQKLNAAEAFENFLQTKYVGQKRFSLEGAEALIPLMDSAIDTAAGQGLDEVVIG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCC
MPHRGRLNVLFNIVGKPLASIFNEFEGQMEQGQIGGSGDVKYHLGSEGQHLQMFGDGEIK
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCEEEEECCCCCEEEEEECCEEE
VSLTANPSHLEAVNPVMEGIVRAKQDYLDKGVDGKTVVPLLLHGDAAFAGLGIVPETINL
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHCCCCCCCCCCH
AKLRGYDVGGTIHIVVNNQIGFTTTPDSSRSMHYATDYAKAFGCPVFHVNGDDPEAVVWV
HHCCCCCCCCEEEEEEECCCCCEECCCCCCCEEHHHHHHHHHCCCEEEECCCCCCEEEEH
GQLATEYRRRFGKDVFIDLVCYRLRGHNEADDPSMTQPKMYELITGRETVRAQYTEDLLG
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHC
RGDLSNEDAEAVVRDFHDQMESVFNEVKEGGKKQAEAQTGITGSQKLPHGLETNISREEL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
LELGQAFANTPEGFNYHPRVAPVAKKRVSSVTEGGIDWAWGELLAFGSLANSGRLVRLAG
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEC
EDSRRGTFTQRHAVAIDPATAEEFNPLHELAQSKGNNGKFLVYNSALTEYAGMGFEYGYS
CCCCCCCCCCCCEEEECCCCHHHCCHHHHHHHCCCCCCCEEEECCHHHHHHCCCCCCCCC
VGNEDSIVAWEAQFGDFANGAQTIIDEYVSSGEAKWGQTSKLILLLPHGYEGQGPDHSSA
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCHHH
RIERFLQLCAEGSMTVAQPSTPANHFHLLRRHALSDLKRPLVIFTPKSMLRNKAAASAPE
HHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHCCCCH
DFTEVTKFQSVINDPNVADAAKVKKVMLVSGKLYYELAKRKEKDGRDDIAIVRIEMLHPI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEEEECCC
PFNRISEALAGYPNAEEVLFVQDEPANQGPWPFYQEHLPELIPNMPKMRRVSRRAQSSTA
CHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TGVAKVHQLEEKQLIDEAFEA
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9004499; 12948626 [H]