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The map label for this gene is fadE

Identifier: 161486539

GI number: 161486539

Start: 291574

End: 294018

Strand: Reverse

Name: fadE

Synonym: S0292

Alternate gene names: 161486539

Gene position: 294018-291574 (Counterclockwise)

Preceding gene: 30061843

Following gene: 30061838

Centisome position: 6.39

GC content: 55.99

Gene sequence:

>2445_bases
ATGATGATTTTGAGTATTCTCGCTACGGTTGTCCTGCTCGGCGCGTTGTTCTATCACCGCGTGAGCTTATTTATCAGCAG
TCTGATTTTGCTCGCCTGGACAGCCGCCCTCGGCGTTGCTGGTCTGTGGTCGGCGTGGGTACTGGTGCCTCTGACCATTA
TCCTCGTGCCATTTAACTTTGCGCCTATGCGTAAGTCGATGATTTCCGCGCCGGTATTTCGCGGTTTCCGTAAGGTGATG
CCGCCGATGTCGCGCACTGAGAAAGAAGCGATTGATGCGGGCACCACCTGGTGGGAGGGCGACTTGTTCCAGGGCAAGCC
GGACTGGAAAAAGCTGCATAACTATCCGCAGCCGCGCCTGACCGCTGAAGAGCAAGCGTTTCTCGACGGCCCGGTAGAAG
AAGCCTGCCGGATGGCGAATGATTTCCAGATTACTCATGAGCTGGCGGATCTGCCACCGGAGTTGTGGGCGTACCTTAAA
GAGCATCGCTTCTTCGCGATGATTATCAAAAAAGAGTACGGCGGACTGGAGTTCTCAGCTTATGCCCAGTCTCGTGTGCT
GCAAAAACTCTCTGGCGTGAGCGGGATCCTGGCGATTACCGTCGGCGTGCCAAACTCATTAGGCCCGGGCGAACTGTTGC
AACATTACGGCACTGACGAGCAGAAAGATCACTATCTGCCGCGTCTGGCGCGTGGTCAGGAGATCCCCTGCTTTGCACTG
ACCAGCCCGGAAGCGGGTTCCGATGCGGGCGCGATTCCGGACACCGGGATTGTCTGCATGGGCGAATGGCAGGGCCAGCA
GGTGCTGGGGATGCGTCTGACCTGGAACAAACGCTACATTACGCTGGCACCGATTGCGACCGTGCTTGGGCTGGCGTTTA
AACTCTCCGACCCGGAAAAATTACTCGGCGGTGCAGAAGATTTAGGCATTACCTGTGCGCTGATCCCAACCACCACGCCG
GGCGTGGAAATTGGTCGTCGCCACTTCCCGCTGAACGTACCGTTCCAGAACGGACCGACGCGCGGTAAAGATGTCTTCGT
GCCGATCGATTACATCATCGGCGGGCCGAAAATGGCCGGGCAAGGCTGGCGGATGCTGGTGGAGTGCCTCTCGGTAGGCC
GCGGCATCACCCTGCCTTCCAACTCAACCGGCGGCGTGAAATCGGTAGCGCTGGCAACGGGCGCGTATTCTCACATTCGC
CGTCAGTTCAAAATCTCTATCGGTAAGATGGAAGGGATTGAAGAGCCGCTGGCGCGTATTGCCGGGAACGCTTATGTAAT
GGATGCTGCGGCATCGCTGATTACCTACGGCATTATGCTCGGCGAAAAACCTGCCGTGCTGTCGGCTATCGTTAAGTATC
ACTGTACCCACCGCGGGCAGCAGTCGATTATTGATGCGATGGATATTACCGGCGGTAAAGGCATTATGCTCGGGCAAAGC
AACTTCCTGGCGCGTGCTTACCAGGGCGCACCGATTGCCATCACCGTTGAAGGGGCTAACATTCTGACCCGCAGCATGAT
GATCTTCGGACAAGGAGCGATTCGTTGCCATCCGTACGTGCTGGAAGAGATGGAAGCGGCGAAGAACAATGACGTCAACG
CGTTCGATAAACTGTTGTTCAAACATATCGGTCACGTCGGTAGCAACAAAGTTCGCAGCTTCTGGCTGGGCCTGACGCGC
GGTTTAACCAGCAGCACGCCAACCGGCGATGCCACTAAACGCTACTATCAGCACCTGAACCGCCTGAGCGCCAACCTCGC
CCTGCTTTCTGATGTCTCGATGGCACTGCTGGGCGGCAGCCTGAAACGTCGTGAGCGTATCTCGGCACGTCTGGGGGATA
TTTTAAGCCAGCTTTACCTCGCCTCTGCCGTTCTGAAGCGTTATGACGACGAAGGCCGTAATGAAGCCGATCTGCCGCTG
GTGCACTGGGGCGTACAGGATGCGCTGTATCAGGCAGAACAGGCAATGGACAATTTACTGCAAAACTTCCCGAACCGCGT
GGTTGCCGGGCTGCTGAATGTGGTGATCTTCCCGACCGGACGTCATTATCTGGCACCGTCTGACAAGCTGGATCATAAAA
TGGCGAAGATTTTACAAGTGCCGAACGCCACTCGTTCACGTATTGGTCGCGGTCAGTACCTGACGCCAAGCGAGCATAAC
CCGGTTGGTTTACTGGAAGAGGCGTTGGTGGATGTGATTGCCGCCGACCCGATTCATCAGCGGATCTGTAAAGAGCTGGG
TAAAAATCTGCCATTTACCCGTCTGGATGAACTGGCGCACAACGCGCTGACGAAGGGGCTGATTGATAAAGATGAAGCCG
CTATTCTGGTGAAAGCGGAAGAAAGCCGTCTGCGCAGTATTAACGTTGATGACTTTGATCCGGAAGAGCTGGCGACGAAG
CCGGTAAAGTTGCCGGAGAAAGTGCGGAAAGTTGAAGCCGCGTAA

Upstream 100 bases:

>100_bases
TTGTAATTATATTGTAAACACATTGCTAAATGTTTTTACATCCACTACAACCATATCATCACAAGTGGTCAGACCTCCTA
CAAGTAAGGGGCTTTTCGTT

Downstream 100 bases:

>100_bases
TTGAATAACGGAGCCGAAAGGCTCCGTTTCTTTATCCGCTAATTATTTAAAATTAAAGCCATCCGGATGGTTTTCCAGGC
TGCCGGTCAACGCCGCGAAC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: ACDH [H]

Number of amino acids: Translated: 814; Mature: 814

Protein sequence:

>814_residues
MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWSAWVLVPLTIILVPFNFAPMRKSMISAPVFRGFRKVM
PPMSRTEKEAIDAGTTWWEGDLFQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
EHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGTDEQKDHYLPRLARGQEIPCFAL
TSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWNKRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTP
GVEIGRRHFPLNVPFQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALATGAYSHIR
RQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAIVKYHCTHRGQQSIIDAMDITGGKGIMLGQS
NFLARAYQGAPIAITVEGANILTRSMMIFGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTR
GLTSSTPTGDATKRYYQHLNRLSANLALLSDVSMALLGGSLKRRERISARLGDILSQLYLASAVLKRYDDEGRNEADLPL
VHWGVQDALYQAEQAMDNLLQNFPNRVVAGLLNVVIFPTGRHYLAPSDKLDHKMAKILQVPNATRSRIGRGQYLTPSEHN
PVGLLEEALVDVIAADPIHQRICKELGKNLPFTRLDELAHNALTKGLIDKDEAAILVKAEESRLRSINVDDFDPEELATK
PVKLPEKVRKVEAA

Sequences:

>Translated_814_residues
MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWSAWVLVPLTIILVPFNFAPMRKSMISAPVFRGFRKVM
PPMSRTEKEAIDAGTTWWEGDLFQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
EHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGTDEQKDHYLPRLARGQEIPCFAL
TSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWNKRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTP
GVEIGRRHFPLNVPFQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALATGAYSHIR
RQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAIVKYHCTHRGQQSIIDAMDITGGKGIMLGQS
NFLARAYQGAPIAITVEGANILTRSMMIFGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTR
GLTSSTPTGDATKRYYQHLNRLSANLALLSDVSMALLGGSLKRRERISARLGDILSQLYLASAVLKRYDDEGRNEADLPL
VHWGVQDALYQAEQAMDNLLQNFPNRVVAGLLNVVIFPTGRHYLAPSDKLDHKMAKILQVPNATRSRIGRGQYLTPSEHN
PVGLLEEALVDVIAADPIHQRICKELGKNLPFTRLDELAHNALTKGLIDKDEAAILVKAEESRLRSINVDDFDPEELATK
PVKLPEKVRKVEAA
>Mature_814_residues
MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWSAWVLVPLTIILVPFNFAPMRKSMISAPVFRGFRKVM
PPMSRTEKEAIDAGTTWWEGDLFQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
EHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGTDEQKDHYLPRLARGQEIPCFAL
TSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWNKRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTP
GVEIGRRHFPLNVPFQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALATGAYSHIR
RQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAIVKYHCTHRGQQSIIDAMDITGGKGIMLGQS
NFLARAYQGAPIAITVEGANILTRSMMIFGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTR
GLTSSTPTGDATKRYYQHLNRLSANLALLSDVSMALLGGSLKRRERISARLGDILSQLYLASAVLKRYDDEGRNEADLPL
VHWGVQDALYQAEQAMDNLLQNFPNRVVAGLLNVVIFPTGRHYLAPSDKLDHKMAKILQVPNATRSRIGRGQYLTPSEHN
PVGLLEEALVDVIAADPIHQRICKELGKNLPFTRLDELAHNALTKGLIDKDEAAILVKAEESRLRSINVDDFDPEELATK
PVKLPEKVRKVEAA

Specific function: Catalyzes the dehydrogenation of acyl-CoA [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=542, Percent_Identity=26.3837638376384, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI4557235, Length=405, Percent_Identity=24.9382716049383, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI4557233, Length=419, Percent_Identity=26.7303102625298, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI76496475, Length=384, Percent_Identity=25.2604166666667, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI4501859, Length=337, Percent_Identity=25.8160237388724, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI226958412, Length=344, Percent_Identity=24.1279069767442, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI87081702, Length=814, Percent_Identity=99.2628992628993, Blast_Score=1664, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985184, Length=410, Percent_Identity=24.6341463414634, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=356, Percent_Identity=23.876404494382, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=332, Percent_Identity=25, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17506239, Length=283, Percent_Identity=25.7950530035336, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508101, Length=284, Percent_Identity=27.4647887323944, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281363737, Length=452, Percent_Identity=26.9911504424779, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24646207, Length=280, Percent_Identity=27.1428571428571, Blast_Score=80, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21356377, Length=303, Percent_Identity=26.0726072607261, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24666513, Length=328, Percent_Identity=26.219512195122, Blast_Score=71, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100
- InterPro:   IPR015396 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N; PF09317 DUF1974 [H]

EC number: NA

Molecular weight: Translated: 89319; Mature: 89319

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWSAWVLVPLTIILVPFNF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDLFQGKPDWKKLHNYPQPRL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEECCCCCCCCCCHHHHCCCCCCCC
TAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLKEHRFFAMIIKKEYGGLEFSA
CCHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCCEEEEEEHHCCCCCHHH
YAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGTDEQKDHYLPRLARGQEIPCFAL
HHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCHHCCHHHHCCCCCCEEEE
TSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWNKRYITLAPIATVLGLAFKLSDPEK
CCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCEEEHHHHHHHHHHHHCCCCHHH
LLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVPFQNGPTRGKDVFVPIDYIIGGPKMAG
HHCCCCCCCEEEEEECCCCCCHHHCCCCCCEECCCCCCCCCCCEEEEEHHHEECCCCCCC
QGWRMLVECLSVGRGITLPSNSTGGVKSVALATGAYSHIRRQFKISIGKMEGIEEPLARI
HHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AGNAYVMDAAASLITYGIMLGEKPAVLSAIVKYHCTHRGQQSIIDAMDITGGKGIMLGQS
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECCC
NFLARAYQGAPIAITVEGANILTRSMMIFGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLF
HHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCEECHHHHHHHHHHCCCCCHHHHHHHH
KHIGHVGSNKVRSFWLGLTRGLTSSTPTGDATKRYYQHLNRLSANLALLSDVSMALLGGS
HHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LKRRERISARLGDILSQLYLASAVLKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDNLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHH
QNFPNRVVAGLLNVVIFPTGRHYLAPSDKLDHKMAKILQVPNATRSRIGRGQYLTPSEHN
HHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCC
PVGLLEEALVDVIAADPIHQRICKELGKNLPFTRLDELAHNALTKGLIDKDEAAILVKAE
CHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
ESRLRSINVDDFDPEELATKPVKLPEKVRKVEAA
HHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWSAWVLVPLTIILVPFNF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDLFQGKPDWKKLHNYPQPRL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEECCCCCCCCCCHHHHCCCCCCCC
TAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLKEHRFFAMIIKKEYGGLEFSA
CCHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCCEEEEEEHHCCCCCHHH
YAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGTDEQKDHYLPRLARGQEIPCFAL
HHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCHHCCHHHHCCCCCCEEEE
TSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWNKRYITLAPIATVLGLAFKLSDPEK
CCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCEEEHHHHHHHHHHHHCCCCHHH
LLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVPFQNGPTRGKDVFVPIDYIIGGPKMAG
HHCCCCCCCEEEEEECCCCCCHHHCCCCCCEECCCCCCCCCCCEEEEEHHHEECCCCCCC
QGWRMLVECLSVGRGITLPSNSTGGVKSVALATGAYSHIRRQFKISIGKMEGIEEPLARI
HHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AGNAYVMDAAASLITYGIMLGEKPAVLSAIVKYHCTHRGQQSIIDAMDITGGKGIMLGQS
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECCC
NFLARAYQGAPIAITVEGANILTRSMMIFGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLF
HHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCEECHHHHHHHHHHCCCCCHHHHHHHH
KHIGHVGSNKVRSFWLGLTRGLTSSTPTGDATKRYYQHLNRLSANLALLSDVSMALLGGS
HHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LKRRERISARLGDILSQLYLASAVLKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDNLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHH
QNFPNRVVAGLLNVVIFPTGRHYLAPSDKLDHKMAKILQVPNATRSRIGRGQYLTPSEHN
HHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCC
PVGLLEEALVDVIAADPIHQRICKELGKNLPFTRLDELAHNALTKGLIDKDEAAILVKAE
CHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
ESRLRSINVDDFDPEELATKPVKLPEKVRKVEAA
HHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]