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The map label for this gene is cpxP

Identifier: 161486410

GI number: 161486410

Start: 3651915

End: 3652415

Strand: Reverse

Name: cpxP

Synonym: S3755

Alternate gene names: 161486410

Gene position: 3652415-3651915 (Counterclockwise)

Preceding gene: 30064795

Following gene: 30064791

Centisome position: 79.41

GC content: 50.1

Gene sequence:

>501_bases
ATGCGCATAGTTACCGCTGCCGTCATGGCCTCAACGCTGGCAGTCAGTTCATTAAGCCACGCTGCTGAAGTCGGTTCAGG
CGATAACTGGCATCCGGGTGAAGAACTTACGCAGCGCAGTACGCAGAGCCATATGTTCGACGGCATAAGTTTAACCGAAC
ATCAGCGTCAGCAGATGCGAGATCTTATGCAACAGGCCCGGCACGAACAGCCTCCTGTTAATGTTAGCGAACTGGAGACA
ATGCATCGCCTTGTCACCGCAGAAAATTTTGATGAAAACGCTGTGCGCGCACAGGCAGAAAAAATGGCGAATGAGCAAAT
TGCTCGTCAGGTTGAGATGGCAAAAGTCCGCAACCAAATGTATCGCCTGTTAACGCCGGAGCAGCAAGCGGTTTTAAACG
AGAAACATCAACAACGAATGGAGCAGTTGCGTGACGTGACGCAATGGCAAAAAAGTTCATCGTTGAAGCTATTGAGTAGT
AGCAACTCACGTTCCCAGTAG

Upstream 100 bases:

>100_bases
CATGACTTTACGTTGTTTTACACCCCCTGACGCATGTTTGCAGCCTGAATCGTAAACTCTCTATCGTTGAATCGCGACAG
AAAGATTTTGGGAGCAAATG

Downstream 100 bases:

>100_bases
TAAACCCTGTTTTCCTTGCCATAGACACCATCCCTGTCTTCCCCCACATGATGTGGGGTTTTTTTTATCCTCAATTTGCC
TGCTGCTTAATGCATTGCAG

Product: periplasmic repressor CpxP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELTQRSTQSHMFDGISLTEHQRQQMRDLMQQARHEQPPVNVSELET
MHRLVTAENFDENAVRAQAEKMANEQIARQVEMAKVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLSS
SNSRSQ

Sequences:

>Translated_166_residues
MRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELTQRSTQSHMFDGISLTEHQRQQMRDLMQQARHEQPPVNVSELET
MHRLVTAENFDENAVRAQAEKMANEQIARQVEMAKVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLSS
SNSRSQ
>Mature_166_residues
MRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELTQRSTQSHMFDGISLTEHQRQQMRDLMQQARHEQPPVNVSELET
MHRLVTAENFDENAVRAQAEKMANEQIARQVEMAKVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLSS
SNSRSQ

Specific function: Aids in combating extracytoplasmic protein-mediated toxicity

COG id: COG3678

COG function: function code UNTP; P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To E.coli spy

Homologues:

Organism=Escherichia coli, GI48994991, Length=166, Percent_Identity=100, Blast_Score=337, Evalue=2e-94,
Organism=Escherichia coli, GI1788039, Length=162, Percent_Identity=26.5432098765432, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CPXP_ECOL6 (P0AE86)

Other databases:

- EMBL:   AE014075
- RefSeq:   NP_756719.2
- ProteinModelPortal:   P0AE86
- SMR:   P0AE86
- EnsemblBacteria:   EBESCT00000041251
- GeneID:   1040200
- GenomeReviews:   AE014075_GR
- KEGG:   ecc:c4865
- GeneTree:   EBGT00050000010082
- HOGENOM:   HBG679676
- OMA:   RARHEQP
- ProtClustDB:   PRK10363
- InterPro:   IPR012899

Pfam domain/function: PF07813 LTXXQ

EC number: NA

Molecular weight: Translated: 18966; Mature: 18966

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELTQRSTQSHMFDGISLTEHQRQQMR
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DLMQQARHEQPPVNVSELETMHRLVTAENFDENAVRAQAEKMANEQIARQVEMAKVRNQM
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLSSSNSRSQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure
MRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELTQRSTQSHMFDGISLTEHQRQQMR
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DLMQQARHEQPPVNVSELETMHRLVTAENFDENAVRAQAEKMANEQIARQVEMAKVRNQM
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLSSSNSRSQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157