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The map label for this gene is ytfL [C]

Identifier: 16124619

GI number: 16124619

Start: 385817

End: 387130

Strand: Direct

Name: ytfL [C]

Synonym: CC_0364

Alternate gene names: 16124619

Gene position: 385817-387130 (Clockwise)

Preceding gene: 16124618

Following gene: 16124625

Centisome position: 9.6

GC content: 67.43

Gene sequence:

>1314_bases
ATGATCCTCGTCTCGCTCGTTGTCGTCCTCTTCCTCGTTCTGCTGAACGGGGTCTTTTCCATGTCCGAACTGGCCGTTGT
CTCGGCGCGCAAGGCTCGCCTGCAGGGCTTCGCCGAGCGGGGGGATCGCGGGGCCAAGCTGGCCTTGGAGATGTCCGAAC
ATCCGACGCGGTTCCTGTCCGCCGTCCAGGTGGGCATCACCCTGATCGGCATCTTCGCCGGCGCCTATGGCCAAGCCACC
ATCGCCGCCGCCCTGGACGCTTGGCTGGAGGCCAGCGTCCCGGCCCTGGCCAAATACTCAGAGGCCATCGCCACGACGCT
CGTCGTCATCGGCCTGACCTATGTCTCGGTGATCCTGGGCGAGCTGGTGCCCAAGCGCCTGGCGCTGATCTTCCCCGACG
CCATCGCCCGCCGCATGGCGCCGTTCCTGGCCGTGGTGGCCACGGTGCTGCGGCCCTTCGTGACCCTGCTCACGGTCTCG
ACCGCCGCCGTGCTGCGCCTGATGGGCGTGCGTGACGAGCGCAACACCAGCGTCACCTCCGAGGAGGTCGAGGCCGTGCT
GGCCGAAGGCGCCGACGCAGGCCTGATCGAGCCCGAGGAGCGCTCGATGATCCAGGAGGTTCTGCGCCTGGGCGATCGTC
CCGTGCGCGTGGCGATGACCCCGCGCCGCGACCTTTTCTGGGTCTCGCTGGCCGACGACACCGAGACCGTGCTCAAGGAG
ATCCGCGCCAGCGCCCACTCGCGCATCGTGGTGGCCACTGAAGGCGACCTCGACGGCGACGTCGGCGTGCTGCTGAAGAA
GGACCTGCTGGACGCCTGTCTCTCGGGCGAACCGCTGGACCTGAAGGCCCACGTCCAGCAGCCGCTGGCCATCCCCGAGA
CCATGTCGCTGCTCAAGGCGCTGCAGCTCTTCAAGTCGACCAGCCTGCACATGGCCCTCGTCGTCGACGAGTTCGGCTCG
TTGCAGGGCGCGATCACGCCGCTGGACCTGCTGGAAATGATCGCCGGCGACTTCCCGGAAGATCACGACGACGACGAAAA
GCGCATCATCCGCCGCGAGGACGGCGGTTGGCTGATCGACGCCCGGCTCGACATTCAGGAGCTCAACGATCATCTCGGCG
AAAACTTCGAGGCCGACGGCGGCTATCACACGGTCGCCGGCCTGATCCTCGACCGCCTGGGCCGGCTGCCGACCGAAGGC
GAGCACGTCGAGATCGGCGGCTTCGACCTCGAGATCGTCGACATGGACGGCTCGCGCATCGACAAGGTCATCCTCAAGCC
CAGCAAGCGCCGGAAGGAAGGCCAGGAGGGGTAG

Upstream 100 bases:

>100_bases
CTAGGAGCCGCGGCGTTTTTCTTTGTATAGTGGTCGAGCAGGGCCCTTGCGCCCCCGCCGCAGTCGCCGTCCGACGACGC
GTCCCTGACCCTGAAGGGCC

Downstream 100 bases:

>100_bases
GGGGTTCGGTGCCGCCTCACTGAAGGCTGTATTGATGGGTCGCCGGGCAGGTCGAGTTTCTGGCGGGAGGCTAGGGTCAA
GTCCGGACCCGTTGCGGACG

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MILVSLVVVLFLVLLNGVFSMSELAVVSARKARLQGFAERGDRGAKLALEMSEHPTRFLSAVQVGITLIGIFAGAYGQAT
IAAALDAWLEASVPALAKYSEAIATTLVVIGLTYVSVILGELVPKRLALIFPDAIARRMAPFLAVVATVLRPFVTLLTVS
TAAVLRLMGVRDERNTSVTSEEVEAVLAEGADAGLIEPEERSMIQEVLRLGDRPVRVAMTPRRDLFWVSLADDTETVLKE
IRASAHSRIVVATEGDLDGDVGVLLKKDLLDACLSGEPLDLKAHVQQPLAIPETMSLLKALQLFKSTSLHMALVVDEFGS
LQGAITPLDLLEMIAGDFPEDHDDDEKRIIRREDGGWLIDARLDIQELNDHLGENFEADGGYHTVAGLILDRLGRLPTEG
EHVEIGGFDLEIVDMDGSRIDKVILKPSKRRKEGQEG

Sequences:

>Translated_437_residues
MILVSLVVVLFLVLLNGVFSMSELAVVSARKARLQGFAERGDRGAKLALEMSEHPTRFLSAVQVGITLIGIFAGAYGQAT
IAAALDAWLEASVPALAKYSEAIATTLVVIGLTYVSVILGELVPKRLALIFPDAIARRMAPFLAVVATVLRPFVTLLTVS
TAAVLRLMGVRDERNTSVTSEEVEAVLAEGADAGLIEPEERSMIQEVLRLGDRPVRVAMTPRRDLFWVSLADDTETVLKE
IRASAHSRIVVATEGDLDGDVGVLLKKDLLDACLSGEPLDLKAHVQQPLAIPETMSLLKALQLFKSTSLHMALVVDEFGS
LQGAITPLDLLEMIAGDFPEDHDDDEKRIIRREDGGWLIDARLDIQELNDHLGENFEADGGYHTVAGLILDRLGRLPTEG
EHVEIGGFDLEIVDMDGSRIDKVILKPSKRRKEGQEG
>Mature_437_residues
MILVSLVVVLFLVLLNGVFSMSELAVVSARKARLQGFAERGDRGAKLALEMSEHPTRFLSAVQVGITLIGIFAGAYGQAT
IAAALDAWLEASVPALAKYSEAIATTLVVIGLTYVSVILGELVPKRLALIFPDAIARRMAPFLAVVATVLRPFVTLLTVS
TAAVLRLMGVRDERNTSVTSEEVEAVLAEGADAGLIEPEERSMIQEVLRLGDRPVRVAMTPRRDLFWVSLADDTETVLKE
IRASAHSRIVVATEGDLDGDVGVLLKKDLLDACLSGEPLDLKAHVQQPLAIPETMSLLKALQLFKSTSLHMALVVDEFGS
LQGAITPLDLLEMIAGDFPEDHDDDEKRIIRREDGGWLIDARLDIQELNDHLGENFEADGGYHTVAGLILDRLGRLPTEG
EHVEIGGFDLEIVDMDGSRIDKVILKPSKRRKEGQEG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=396, Percent_Identity=27.2727272727273, Blast_Score=164, Evalue=2e-40,
Organism=Escherichia coli, GI1790664, Length=427, Percent_Identity=29.5081967213115, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI87082033, Length=370, Percent_Identity=30.5405405405405, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI145693175, Length=422, Percent_Identity=27.9620853080569, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788119, Length=263, Percent_Identity=33.0798479087452, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1786879, Length=250, Percent_Identity=30.8, Blast_Score=111, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47450; Mature: 47450

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVSLVVVLFLVLLNGVFSMSELAVVSARKARLQGFAERGDRGAKLALEMSEHPTRFLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHH
AVQVGITLIGIFAGAYGQATIAAALDAWLEASVPALAKYSEAIATTLVVIGLTYVSVILG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELVPKRLALIFPDAIARRMAPFLAVVATVLRPFVTLLTVSTAAVLRLMGVRDERNTSVTS
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
EEVEAVLAEGADAGLIEPEERSMIQEVLRLGDRPVRVAMTPRRDLFWVSLADDTETVLKE
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCHHHHHHH
IRASAHSRIVVATEGDLDGDVGVLLKKDLLDACLSGEPLDLKAHVQQPLAIPETMSLLKA
HHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHH
LQLFKSTSLHMALVVDEFGSLQGAITPLDLLEMIAGDFPEDHDDDEKRIIRREDGGWLID
HHHHHCCCCEEEEEEHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHEECCCCEEEE
ARLDIQELNDHLGENFEADGGYHTVAGLILDRLGRLPTEGEHVEIGGFDLEIVDMDGSRI
EECCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCEEEEEEECCCCHH
DKVILKPSKRRKEGQEG
HHHHCCCCHHCCCCCCC
>Mature Secondary Structure
MILVSLVVVLFLVLLNGVFSMSELAVVSARKARLQGFAERGDRGAKLALEMSEHPTRFLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHH
AVQVGITLIGIFAGAYGQATIAAALDAWLEASVPALAKYSEAIATTLVVIGLTYVSVILG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELVPKRLALIFPDAIARRMAPFLAVVATVLRPFVTLLTVSTAAVLRLMGVRDERNTSVTS
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
EEVEAVLAEGADAGLIEPEERSMIQEVLRLGDRPVRVAMTPRRDLFWVSLADDTETVLKE
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCHHHHHHH
IRASAHSRIVVATEGDLDGDVGVLLKKDLLDACLSGEPLDLKAHVQQPLAIPETMSLLKA
HHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHH
LQLFKSTSLHMALVVDEFGSLQGAITPLDLLEMIAGDFPEDHDDDEKRIIRREDGGWLID
HHHHHCCCCEEEEEEHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHEECCCCEEEE
ARLDIQELNDHLGENFEADGGYHTVAGLILDRLGRLPTEGEHVEIGGFDLEIVDMDGSRI
EECCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCEEEEEEECCCCHH
DKVILKPSKRRKEGQEG
HHHHCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]