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The map label for this gene is wecB [H]

Identifier: 160902739

GI number: 160902739

Start: 1373796

End: 1374923

Strand: Direct

Name: wecB [H]

Synonym: Pmob_1284

Alternate gene names: 160902739

Gene position: 1373796-1374923 (Clockwise)

Preceding gene: 160902738

Following gene: 160902740

Centisome position: 63.32

GC content: 30.32

Gene sequence:

>1128_bases
ATGAATAAAATAATGACAATAGTTGGTACAAGGCCTGAATTAATAAAACTGAGTTTAGTAATTAAGGAACTTGATAAACA
CACGAACCATATATTAGTCCACACAGGGCAAAATTATGATTATGAATTAAATCAGATTTTTTTTAAAGATTTAGAAATTA
GAAAGCCAAATTACTACTTAAATGTCGCAGAAGAAAATCTTGCAAAAACCATTGCAAAAATAATAGAAAAATCAGATGAA
GTTATGGAAATAGAAAAACCAGAAGCTATTTTAATATATGGGGATACAAACAGTTGCTTATCAGTTATTCCTGCTAAAAG
GAGAAAAATACCTATTTTTCATATGGAAGCAGGAAATAGATGCTTTGATCAGAGAGTCCCAGAAGAATTAAATCGGAAAA
TCATAGATCATTTATCGGATATAAATATGGTTCTGACAGAACATGCACGGCGATACCTTATTCGAGAAGGAATAAACCCT
GAAACTATAATCAAGGTTGGTTCTTCCTTAGTAGAAATTTTTGAGCACTTCAAATCTAAGATACAAAATTCAAACATTTT
GAACGAATTAGGATTAAAAGAAAAGGATTACATAGTAATCAGTCTTCACAGGGAAGAGAATGTTGATAATCCCAGAAACT
TCGATAATTTTCTAAAATCCCTGTCGAATATTCAAAAATACTATGATAAAAAAATAATTATTTCTACTCATCCAAGGACA
AGAAAAAAGATTGAACAAAATGCAACTTTTTTCAAAGATGATAATATAAGTTTTTTAAAGCCCTTTGGTTTTTTTGATTA
TGTTAAATTAGAAACCAACTCTTTTTGTGTATTATCTGATAGTGGAACTATAACAGAAGAAGCTTCTATTTTGAAATTTC
CTGCCGTTACCTTAAGGCAGGCTCATGAAAGGCCCGAAGGAATGGATGAAGGAACATTAATAATGACAGAAATTAACTCT
GACAGTATAATAAACGCTATTAATATCGTAACAAACCAGGCAAAAGAAGGCTTTGAGTTAAAAACAGTCTCAGATTACGA
ATCAAAAAATGTTTCACAGAAAGTGATAAGAATAATCGTCAGTTATATAGAATACGTCAACAGAACAGTATGGTTTAAGC
ACACATAA

Upstream 100 bases:

>100_bases
AAGACTACAAAAATGGCGGAACTAAGCCAATAGTGAGTGAAGGGTTTTAGTTAAAAGTTAAAATTAACTTTAAAAAATAC
AAATTAAAGGAAGAATATGA

Downstream 100 bases:

>100_bases
AATGTGGAGGTGAATACTAACGAAAAATATATTAGTTTTAGGCTCTTCGGGGATGTTAGGCCATGTTGTAGTAAATTATT
TTGAAGAGAAAAACTATAAC

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MNKIMTIVGTRPELIKLSLVIKELDKHTNHILVHTGQNYDYELNQIFFKDLEIRKPNYYLNVAEENLAKTIAKIIEKSDE
VMEIEKPEAILIYGDTNSCLSVIPAKRRKIPIFHMEAGNRCFDQRVPEELNRKIIDHLSDINMVLTEHARRYLIREGINP
ETIIKVGSSLVEIFEHFKSKIQNSNILNELGLKEKDYIVISLHREENVDNPRNFDNFLKSLSNIQKYYDKKIIISTHPRT
RKKIEQNATFFKDDNISFLKPFGFFDYVKLETNSFCVLSDSGTITEEASILKFPAVTLRQAHERPEGMDEGTLIMTEINS
DSIINAINIVTNQAKEGFELKTVSDYESKNVSQKVIRIIVSYIEYVNRTVWFKHT

Sequences:

>Translated_375_residues
MNKIMTIVGTRPELIKLSLVIKELDKHTNHILVHTGQNYDYELNQIFFKDLEIRKPNYYLNVAEENLAKTIAKIIEKSDE
VMEIEKPEAILIYGDTNSCLSVIPAKRRKIPIFHMEAGNRCFDQRVPEELNRKIIDHLSDINMVLTEHARRYLIREGINP
ETIIKVGSSLVEIFEHFKSKIQNSNILNELGLKEKDYIVISLHREENVDNPRNFDNFLKSLSNIQKYYDKKIIISTHPRT
RKKIEQNATFFKDDNISFLKPFGFFDYVKLETNSFCVLSDSGTITEEASILKFPAVTLRQAHERPEGMDEGTLIMTEINS
DSIINAINIVTNQAKEGFELKTVSDYESKNVSQKVIRIIVSYIEYVNRTVWFKHT
>Mature_375_residues
MNKIMTIVGTRPELIKLSLVIKELDKHTNHILVHTGQNYDYELNQIFFKDLEIRKPNYYLNVAEENLAKTIAKIIEKSDE
VMEIEKPEAILIYGDTNSCLSVIPAKRRKIPIFHMEAGNRCFDQRVPEELNRKIIDHLSDINMVLTEHARRYLIREGINP
ETIIKVGSSLVEIFEHFKSKIQNSNILNELGLKEKDYIVISLHREENVDNPRNFDNFLKSLSNIQKYYDKKIIISTHPRT
RKKIEQNATFFKDDNISFLKPFGFFDYVKLETNSFCVLSDSGTITEEASILKFPAVTLRQAHERPEGMDEGTLIMTEINS
DSIINAINIVTNQAKEGFELKTVSDYESKNVSQKVIRIIVSYIEYVNRTVWFKHT

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=343, Percent_Identity=27.9883381924198, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 43576; Mature: 43576

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIMTIVGTRPELIKLSLVIKELDKHTNHILVHTGQNYDYELNQIFFKDLEIRKPNYYL
CCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCEEECCCEEE
NVAEENLAKTIAKIIEKSDEVMEIEKPEAILIYGDTNSCLSVIPAKRRKIPIFHMEAGNR
EEHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCHHHHHCCCCCCCCCEEEECCCCC
CFDQRVPEELNRKIIDHLSDINMVLTEHARRYLIREGINPETIIKVGSSLVEIFEHFKSK
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IQNSNILNELGLKEKDYIVISLHREENVDNPRNFDNFLKSLSNIQKYYDKKIIISTHPRT
HCCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCHH
RKKIEQNATFFKDDNISFLKPFGFFDYVKLETNSFCVLSDSGTITEEASILKFPAVTLRQ
HHHHHHCCCEEECCCCCEEECCCCEEEEEEECCCEEEEECCCCCCCCCHHHCCCHHHHHH
AHERPEGMDEGTLIMTEINSDSIINAINIVTNQAKEGFELKTVSDYESKNVSQKVIRIIV
HHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCHHHCCHHHHHHHHHH
SYIEYVNRTVWFKHT
HHHHHHCCEEEEECC
>Mature Secondary Structure
MNKIMTIVGTRPELIKLSLVIKELDKHTNHILVHTGQNYDYELNQIFFKDLEIRKPNYYL
CCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCEEECCCEEE
NVAEENLAKTIAKIIEKSDEVMEIEKPEAILIYGDTNSCLSVIPAKRRKIPIFHMEAGNR
EEHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCHHHHHCCCCCCCCCEEEECCCCC
CFDQRVPEELNRKIIDHLSDINMVLTEHARRYLIREGINPETIIKVGSSLVEIFEHFKSK
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IQNSNILNELGLKEKDYIVISLHREENVDNPRNFDNFLKSLSNIQKYYDKKIIISTHPRT
HCCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCHH
RKKIEQNATFFKDDNISFLKPFGFFDYVKLETNSFCVLSDSGTITEEASILKFPAVTLRQ
HHHHHHCCCEEECCCCCEEECCCCEEEEEEECCCEEEEECCCCCCCCCHHHCCCHHHHHH
AHERPEGMDEGTLIMTEINSDSIINAINIVTNQAKEGFELKTVSDYESKNVSQKVIRIIV
HHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCHHHCCHHHHHHHHHH
SYIEYVNRTVWFKHT
HHHHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]