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The map label for this gene is hppA [H]

Identifier: 160902495

GI number: 160902495

Start: 1097666

End: 1099840

Strand: Direct

Name: hppA [H]

Synonym: Pmob_1032

Alternate gene names: 160902495

Gene position: 1097666-1099840 (Clockwise)

Preceding gene: 160902492

Following gene: 160902508

Centisome position: 50.59

GC content: 39.08

Gene sequence:

>2175_bases
GTGGGTAGTCTATGGATTCTGGCAATAGTTCCAGTAATAGCTTTAATATTTGCAAGTGTTAACTTTAGACAGGTCGTTGT
TTTAGACGAAGGTACAGAGAAGATGCAACACATTGCAAAGGCTATTAGAATTGGTGCTTCCGCCTTTGTTAACCACGAGC
TTAAAGTATTGACGATTTATGGAATATTTATCGCTTTAGCTTTAGGTATCGTGGTAGAGTGGTATGTTGGAGCCGCTTTT
GTAATGGGGGCTTTTATGAGTGCCCTTGCTGGATACATAGGTATGAAAATAGCTACTTACGCTAACGTCAGAGTTAGCAA
TAAAGCTCGTACAGAGAAAAGTATTGGAAAAACTCTGAAAGTTGCATTTCAAGGTGGAAGCGTTATGGGTCTTAGCGTTT
CTGGATTGGCTCTATTAGGTTTATTTTTAGTATATATTATCTTTGGAAATTGGTTAGGACAGCTTTCTGCAGAAAATTTG
GTAATCAAAGTCAATTGGTTGGGAATAAATTATATTCCTTTCACCATGACTGTTTCAGGATATGCCCTTGGATGCTCAAT
AATCGCTATGTTTGATAGGGTTGGTGGAGGAATTTACACAAAAGCTGCGGACATGGGAGCAGACTTGGTTGGAAAAACAG
AATTGGCTTTACCGGAAGATGATGCACGAAATCCCGCAACTATCGCCGATAACGTGGGAGATGATGTTGGAGATGTTGCA
GGACTTGGGGCAGATTTGTTGGAAAGTTATGTAGGTGCGGTAATTTCATCTATAGTTCTAATATTATATACTCATTTCCT
TTTGGGACCTCAAAACTTTTCTTATGATTCCACAATGAGATTAACTTACTATCCTATACTTTTTATATCTTTAGGATTAA
TTTCTTCGATGATTGGAATATTGTATATAATCTTAAAAAAACCTTCAAATGATCCCCATAGAGATTTGAATATATCTTTG
ATGACATCAGCATTTTTAACTGTAATTTTAACTTTTTTCCTTAGCTTTTTCTACTTGAGGGGCATCAGTATTACCGAATT
TCAAAATATCGGTTTCAGATTGGGATACTTCTCCCCTTGGTTGGCAGCTTTCATCGGTATAGTAGACGGTATTTTTATGG
GACTTATAGCAGAATATTACACTAATGATGCATACCATCCTACAAAAGAATTGAGTGAATTCGCTAAGGGTGGTTCAGCT
ATTGTCATTACAAAAGGATTAGCGTTGGGAATGGAAAGCGTTCTTTTGCCTGTTTTCCTTTTGATGTTGGGAATTCTTGT
GTCCTTCGAAATAGCAGGATTGTATGGTGTAGCAATGGCAGCTTTGGGTATGCTTTCTTTCGTTGCCACAACGGTTTCAG
TTGATTCGTACGGTCCAATAGCAGATAATGCTGGTGGGATAAGCGAAATGGCAAAATTGCCGCCTGAAGTTAGAGAGATA
ACCGATAAACTAGACTCTGTAGGGAACACAACGGCTGCTATAGGAAAAGGTTTTGCTATCGGTTCGGCTGCTTTAGCGGC
ATTAGCTCTCTTCGCATCTTTTATTTATTCTCAAGCTGGTCCTGGAGATGGAGGAGTAGGGCATTTAGAAAATATTCTGA
TCTTGAACATGATAGATTCTAGAACAATAGCCGGTGCTATTTTCGGCGCGGCATTACCTTTCTTTTTTAGTTCTTTTCTA
ATAAATGCCGTGGTAAATGCAGCTAACAAGATGGTGGATGAGGTAAGAAGACAGTTTAGAGAAATCCCTGGATTGATGGA
GGGCACAACAGATCCAGATTACGAAAGATGTATCAGGATTAGTAGTGAAGGTTCGCTAAGTCAAATAAAATTCCCTGCCC
TTATCGCCACTCTAACCCCTATAATTTCTGGATTTTTACTAGGACCAAACTTTGTAGGAGGACTTTTGATTGGAACTACT
CTCAGTGGTGTTATGTTAGCAATATTTACAGCTAATTCTGGAGGTGCTTGGGACAACGCAAAAAAGAGAATAGAAGCTGG
AGGCGTTGAAGGAGAAGGGAAAGGTACCGATGCCCATAAAGCAGCAGTTGTGGGTGATACAGTTGGAGATCCACTGAAAG
ATACTGTTGGCCCTTCTCTAGATATACTAATCAAGATTATGGCGGTAACTTCCCTTATAACCGTTTCAATCTTTAAAGTG
TATCATCTATTTTGA

Upstream 100 bases:

>100_bases
ACTGCCATTTTTAAAACTTATTTTTTTGAGTAGAGGATGGTATAATAAAATGGGGTATAATGTTATACTTCAAATTTCAC
AACACTTTGGAGGTGAAACA

Downstream 100 bases:

>100_bases
AAACAAAATCCCGAGGTTGTACATTTAATTGCCTCGGGATTTTAATTCAGTATAATTAAATTCTTAATCCACCGTCTATC
CTTATAACTTGTCCCGTTAT

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase; Tm-PPase [H]

Number of amino acids: Translated: 724; Mature: 723

Protein sequence:

>724_residues
MGSLWILAIVPVIALIFASVNFRQVVVLDEGTEKMQHIAKAIRIGASAFVNHELKVLTIYGIFIALALGIVVEWYVGAAF
VMGAFMSALAGYIGMKIATYANVRVSNKARTEKSIGKTLKVAFQGGSVMGLSVSGLALLGLFLVYIIFGNWLGQLSAENL
VIKVNWLGINYIPFTMTVSGYALGCSIIAMFDRVGGGIYTKAADMGADLVGKTELALPEDDARNPATIADNVGDDVGDVA
GLGADLLESYVGAVISSIVLILYTHFLLGPQNFSYDSTMRLTYYPILFISLGLISSMIGILYIILKKPSNDPHRDLNISL
MTSAFLTVILTFFLSFFYLRGISITEFQNIGFRLGYFSPWLAAFIGIVDGIFMGLIAEYYTNDAYHPTKELSEFAKGGSA
IVITKGLALGMESVLLPVFLLMLGILVSFEIAGLYGVAMAALGMLSFVATTVSVDSYGPIADNAGGISEMAKLPPEVREI
TDKLDSVGNTTAAIGKGFAIGSAALAALALFASFIYSQAGPGDGGVGHLENILILNMIDSRTIAGAIFGAALPFFFSSFL
INAVVNAANKMVDEVRRQFREIPGLMEGTTDPDYERCIRISSEGSLSQIKFPALIATLTPIISGFLLGPNFVGGLLIGTT
LSGVMLAIFTANSGGAWDNAKKRIEAGGVEGEGKGTDAHKAAVVGDTVGDPLKDTVGPSLDILIKIMAVTSLITVSIFKV
YHLF

Sequences:

>Translated_724_residues
MGSLWILAIVPVIALIFASVNFRQVVVLDEGTEKMQHIAKAIRIGASAFVNHELKVLTIYGIFIALALGIVVEWYVGAAF
VMGAFMSALAGYIGMKIATYANVRVSNKARTEKSIGKTLKVAFQGGSVMGLSVSGLALLGLFLVYIIFGNWLGQLSAENL
VIKVNWLGINYIPFTMTVSGYALGCSIIAMFDRVGGGIYTKAADMGADLVGKTELALPEDDARNPATIADNVGDDVGDVA
GLGADLLESYVGAVISSIVLILYTHFLLGPQNFSYDSTMRLTYYPILFISLGLISSMIGILYIILKKPSNDPHRDLNISL
MTSAFLTVILTFFLSFFYLRGISITEFQNIGFRLGYFSPWLAAFIGIVDGIFMGLIAEYYTNDAYHPTKELSEFAKGGSA
IVITKGLALGMESVLLPVFLLMLGILVSFEIAGLYGVAMAALGMLSFVATTVSVDSYGPIADNAGGISEMAKLPPEVREI
TDKLDSVGNTTAAIGKGFAIGSAALAALALFASFIYSQAGPGDGGVGHLENILILNMIDSRTIAGAIFGAALPFFFSSFL
INAVVNAANKMVDEVRRQFREIPGLMEGTTDPDYERCIRISSEGSLSQIKFPALIATLTPIISGFLLGPNFVGGLLIGTT
LSGVMLAIFTANSGGAWDNAKKRIEAGGVEGEGKGTDAHKAAVVGDTVGDPLKDTVGPSLDILIKIMAVTSLITVSIFKV
YHLF
>Mature_723_residues
GSLWILAIVPVIALIFASVNFRQVVVLDEGTEKMQHIAKAIRIGASAFVNHELKVLTIYGIFIALALGIVVEWYVGAAFV
MGAFMSALAGYIGMKIATYANVRVSNKARTEKSIGKTLKVAFQGGSVMGLSVSGLALLGLFLVYIIFGNWLGQLSAENLV
IKVNWLGINYIPFTMTVSGYALGCSIIAMFDRVGGGIYTKAADMGADLVGKTELALPEDDARNPATIADNVGDDVGDVAG
LGADLLESYVGAVISSIVLILYTHFLLGPQNFSYDSTMRLTYYPILFISLGLISSMIGILYIILKKPSNDPHRDLNISLM
TSAFLTVILTFFLSFFYLRGISITEFQNIGFRLGYFSPWLAAFIGIVDGIFMGLIAEYYTNDAYHPTKELSEFAKGGSAI
VITKGLALGMESVLLPVFLLMLGILVSFEIAGLYGVAMAALGMLSFVATTVSVDSYGPIADNAGGISEMAKLPPEVREIT
DKLDSVGNTTAAIGKGFAIGSAALAALALFASFIYSQAGPGDGGVGHLENILILNMIDSRTIAGAIFGAALPFFFSSFLI
NAVVNAANKMVDEVRRQFREIPGLMEGTTDPDYERCIRISSEGSLSQIKFPALIATLTPIISGFLLGPNFVGGLLIGTTL
SGVMLAIFTANSGGAWDNAKKRIEAGGVEGEGKGTDAHKAAVVGDTVGDPLKDTVGPSLDILIKIMAVTSLITVSIFKVY
HLF

Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 76849; Mature: 76718

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSLWILAIVPVIALIFASVNFRQVVVLDEGTEKMQHIAKAIRIGASAFVNHELKVLTIY
CCCCHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHCHHHHHCCCCHHHHHH
GIFIALALGIVVEWYVGAAFVMGAFMSALAGYIGMKIATYANVRVSNKARTEKSIGKTLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECEEECCHHHHHHHHCCEEE
VAFQGGSVMGLSVSGLALLGLFLVYIIFGNWLGQLSAENLVIKVNWLGINYIPFTMTVSG
EEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEEEEEECC
YALGCSIIAMFDRVGGGIYTKAADMGADLVGKTELALPEDDARNPATIADNVGDDVGDVA
HHHHHHHHHHHHHHCCCCEEHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHH
GLGADLLESYVGAVISSIVLILYTHFLLGPQNFSYDSTMRLTYYPILFISLGLISSMIGI
HCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
LYIILKKPSNDPHRDLNISLMTSAFLTVILTFFLSFFYLRGISITEFQNIGFRLGYFSPW
HHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEECCCHHH
LAAFIGIVDGIFMGLIAEYYTNDAYHPTKELSEFAKGGSAIVITKGLALGMESVLLPVFL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHH
LMLGILVSFEIAGLYGVAMAALGMLSFVATTVSVDSYGPIADNAGGISEMAKLPPEVREI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHH
TDKLDSVGNTTAAIGKGFAIGSAALAALALFASFIYSQAGPGDGGVGHLENILILNMIDS
HHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEEEEEECCC
RTIAGAIFGAALPFFFSSFLINAVVNAANKMVDEVRRQFREIPGLMEGTTDPDYERCIRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEE
SSEGSLSQIKFPALIATLTPIISGFLLGPNFVGGLLIGTTLSGVMLAIFTANSGGAWDNA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCHHH
KKRIEAGGVEGEGKGTDAHKAAVVGDTVGDPLKDTVGPSLDILIKIMAVTSLITVSIFKV
HHHHHCCCCCCCCCCCCCHHHEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
YHLF
HHCC
>Mature Secondary Structure 
GSLWILAIVPVIALIFASVNFRQVVVLDEGTEKMQHIAKAIRIGASAFVNHELKVLTIY
CCCHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHCHHHHHCCCCHHHHHH
GIFIALALGIVVEWYVGAAFVMGAFMSALAGYIGMKIATYANVRVSNKARTEKSIGKTLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECEEECCHHHHHHHHCCEEE
VAFQGGSVMGLSVSGLALLGLFLVYIIFGNWLGQLSAENLVIKVNWLGINYIPFTMTVSG
EEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEEEEEECC
YALGCSIIAMFDRVGGGIYTKAADMGADLVGKTELALPEDDARNPATIADNVGDDVGDVA
HHHHHHHHHHHHHHCCCCEEHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHH
GLGADLLESYVGAVISSIVLILYTHFLLGPQNFSYDSTMRLTYYPILFISLGLISSMIGI
HCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
LYIILKKPSNDPHRDLNISLMTSAFLTVILTFFLSFFYLRGISITEFQNIGFRLGYFSPW
HHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEECCCHHH
LAAFIGIVDGIFMGLIAEYYTNDAYHPTKELSEFAKGGSAIVITKGLALGMESVLLPVFL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHH
LMLGILVSFEIAGLYGVAMAALGMLSFVATTVSVDSYGPIADNAGGISEMAKLPPEVREI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHH
TDKLDSVGNTTAAIGKGFAIGSAALAALALFASFIYSQAGPGDGGVGHLENILILNMIDS
HHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEEEEEECCC
RTIAGAIFGAALPFFFSSFLINAVVNAANKMVDEVRRQFREIPGLMEGTTDPDYERCIRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEE
SSEGSLSQIKFPALIATLTPIISGFLLGPNFVGGLLIGTTLSGVMLAIFTANSGGAWDNA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCHHH
KKRIEAGGVEGEGKGTDAHKAAVVGDTVGDPLKDTVGPSLDILIKIMAVTSLITVSIFKV
HHHHHCCCCCCCCCCCCCHHHEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
YHLF
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571; 9440516; 11343697 [H]