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The map label for this gene is obgE

Identifier: 160902490

GI number: 160902490

Start: 1093815

End: 1095137

Strand: Direct

Name: obgE

Synonym: Pmob_1027

Alternate gene names: 160902490

Gene position: 1093815-1095137 (Clockwise)

Preceding gene: 160902489

Following gene: 160902491

Centisome position: 50.42

GC content: 35.3

Gene sequence:

>1323_bases
TTGATCGGTGATTTTGTAGATGAGGTGAACATCAAAGTGATTGCTGGAAAAGGAGGCGATGGAGCTGTAAGCTTTAGAAG
AGAAAAATTTGTAGAAAAAGGCGGACCAGATGGTGGAGACGGAGGAGATGGTGGTTCGATCATCATCAAATCAACCCTCA
ATAAAAATACATTGGTAGATTTTAAATACAAGAAGATTTTTAGAGCAGAAAACGGGGAAAACGGTAAAAATAAAAATAAA
GCTGGAAAAGCCGGAGAAGATGTTTTGATTGAGGTACCTGTTGGCACTTGTATCTATGATCTTGAAACCAACGAACTGCT
TTCAGATTTAAAAGCTCCACAGCAATATTTGGTTGTTGCTCGTGGTGGTAAGGGTGGCAGAGGAAATGCAAGATTTGCAA
CTTCAACTCTACAAGTTCCAAGGATCGCTGAAAAAGGTGTGGAAGGTGAAGTCAAAAATCTAAAGCTCATTTTAAAAATT
GTCGCAGATGTTGGCTTGATTGGTTATCCTAACGTTGGTAAATCAACATTAATTTCAAGGATTTCAAACGCCAAAGTGGA
AATCGCTGATTACCCTTTTACAACTATAGTTCCAAATTTAGGTGTGGTAAAAGTCGACACAGATTATTCTTTCGTAGTAG
CTGATATCCCCGGCCTTATAGAGGGAGCACATTTGGGAAAAGGTCTAGGAGATCAATTTCTAAGGCATATTGAAAGATGT
TCTGTTTTAGTACATCTTATCGATATATCTTGTTTTGAAAGAGATGACCCGGTAGAGGATTATATAAATATTAGAAAAGA
ATTAGAGTCTTTTTCTCATATTCTTTTGAAAAAGAAAGAGATTATTGTTGCAAATAAGATAGATGCGGTAGACAAAGACA
CCCTCGAAAAGAGATTGACGGATTTCAAAAATAGAACGGGAAAAGATATTTTCCCAATTTCCGCTTATACTGGTGAAAAC
ATTCAAGAGCTCATAACTATGGTATGGAGTCATATAAGCAAAGAAAAAATTGAGCAGCAAAAGTTCTTCCAAAAAAGGTT
AAAATCCAATGTCACAGAAAAAATAAAAATACAACCTGTCAACTATGAACCCGATCCTTTTATAAAAATCAACGTTGTAA
AGTTGGATAATGAAACATTTGAAGTTGTGGGAGACGGCATTGAAAAGTTGCTAAGTAGATACGATATCCATCAAAAAGAT
TCTCGTCTGTTAATTTTAAATACATTAGAAAAAAACGGATTGAATAAAATTCTAAGAAATGCAGGAGTTAAAGAAGGAGA
CACGGTGTACATTGGAAATTTTTCTTTTGAATACATACCATAA

Upstream 100 bases:

>100_bases
ATCCACGTAGAACCTTTAGGGAACAACGAGGAAGAAGAATTTGGATTCGATAAAAATTCTATTAAAAGAATTTTTGATAA
ATAAGTGGAGGTGTAACGTT

Downstream 100 bases:

>100_bases
GAAAAGGTGTTTATTATGCTAATGCTTTTTGGAGGTAGTTTTAATCCTCCTCATATAGGTCATAGAATAATTGCCGAAAT
AGCTTATGATGAATTTAACC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MIGDFVDEVNIKVIAGKGGDGAVSFRREKFVEKGGPDGGDGGDGGSIIIKSTLNKNTLVDFKYKKIFRAENGENGKNKNK
AGKAGEDVLIEVPVGTCIYDLETNELLSDLKAPQQYLVVARGGKGGRGNARFATSTLQVPRIAEKGVEGEVKNLKLILKI
VADVGLIGYPNVGKSTLISRISNAKVEIADYPFTTIVPNLGVVKVDTDYSFVVADIPGLIEGAHLGKGLGDQFLRHIERC
SVLVHLIDISCFERDDPVEDYINIRKELESFSHILLKKKEIIVANKIDAVDKDTLEKRLTDFKNRTGKDIFPISAYTGEN
IQELITMVWSHISKEKIEQQKFFQKRLKSNVTEKIKIQPVNYEPDPFIKINVVKLDNETFEVVGDGIEKLLSRYDIHQKD
SRLLILNTLEKNGLNKILRNAGVKEGDTVYIGNFSFEYIP

Sequences:

>Translated_440_residues
MIGDFVDEVNIKVIAGKGGDGAVSFRREKFVEKGGPDGGDGGDGGSIIIKSTLNKNTLVDFKYKKIFRAENGENGKNKNK
AGKAGEDVLIEVPVGTCIYDLETNELLSDLKAPQQYLVVARGGKGGRGNARFATSTLQVPRIAEKGVEGEVKNLKLILKI
VADVGLIGYPNVGKSTLISRISNAKVEIADYPFTTIVPNLGVVKVDTDYSFVVADIPGLIEGAHLGKGLGDQFLRHIERC
SVLVHLIDISCFERDDPVEDYINIRKELESFSHILLKKKEIIVANKIDAVDKDTLEKRLTDFKNRTGKDIFPISAYTGEN
IQELITMVWSHISKEKIEQQKFFQKRLKSNVTEKIKIQPVNYEPDPFIKINVVKLDNETFEVVGDGIEKLLSRYDIHQKD
SRLLILNTLEKNGLNKILRNAGVKEGDTVYIGNFSFEYIP
>Mature_440_residues
MIGDFVDEVNIKVIAGKGGDGAVSFRREKFVEKGGPDGGDGGDGGSIIIKSTLNKNTLVDFKYKKIFRAENGENGKNKNK
AGKAGEDVLIEVPVGTCIYDLETNELLSDLKAPQQYLVVARGGKGGRGNARFATSTLQVPRIAEKGVEGEVKNLKLILKI
VADVGLIGYPNVGKSTLISRISNAKVEIADYPFTTIVPNLGVVKVDTDYSFVVADIPGLIEGAHLGKGLGDQFLRHIERC
SVLVHLIDISCFERDDPVEDYINIRKELESFSHILLKKKEIIVANKIDAVDKDTLEKRLTDFKNRTGKDIFPISAYTGEN
IQELITMVWSHISKEKIEQQKFFQKRLKSNVTEKIKIQPVNYEPDPFIKINVVKLDNETFEVVGDGIEKLLSRYDIHQKD
SRLLILNTLEKNGLNKILRNAGVKEGDTVYIGNFSFEYIP

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=321, Percent_Identity=38.6292834890966, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI111955139, Length=368, Percent_Identity=32.3369565217391, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI111955063, Length=236, Percent_Identity=36.4406779661017, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI58761500, Length=147, Percent_Identity=35.3741496598639, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4758796, Length=110, Percent_Identity=35.4545454545455, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1789574, Length=337, Percent_Identity=49.2581602373887, Blast_Score=276, Evalue=1e-75,
Organism=Escherichia coli, GI1787454, Length=300, Percent_Identity=27.6666666666667, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1790615, Length=184, Percent_Identity=30.4347826086957, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=312, Percent_Identity=39.7435897435897, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17552324, Length=349, Percent_Identity=29.512893982808, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17509631, Length=147, Percent_Identity=34.6938775510204, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17555344, Length=110, Percent_Identity=34.5454545454545, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=270, Percent_Identity=36.2962962962963, Blast_Score=122, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6319281, Length=128, Percent_Identity=36.71875, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321612, Length=125, Percent_Identity=36.8, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321649, Length=172, Percent_Identity=26.7441860465116, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI20129375, Length=338, Percent_Identity=38.1656804733728, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24585318, Length=290, Percent_Identity=35.8620689655172, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24640873, Length=149, Percent_Identity=32.8859060402685, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640877, Length=149, Percent_Identity=32.8859060402685, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640875, Length=149, Percent_Identity=32.8859060402685, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17981711, Length=118, Percent_Identity=37.2881355932203, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_PETMO (A9BK05)

Other databases:

- EMBL:   CP000879
- RefSeq:   YP_001568071.1
- ProteinModelPortal:   A9BK05
- SMR:   A9BK05
- GeneID:   5758012
- GenomeReviews:   CP000879_GR
- KEGG:   pmo:Pmob_1027
- HOGENOM:   HBG716038
- OMA:   PTRQAPN
- ProtClustDB:   PRK12297
- BioCyc:   PMOB403833:PMOB_1027-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 48840; Mature: 48840

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGDFVDEVNIKVIAGKGGDGAVSFRREKFVEKGGPDGGDGGDGGSIIIKSTLNKNTLVD
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCEEE
FKYKKIFRAENGENGKNKNKAGKAGEDVLIEVPVGTCIYDLETNELLSDLKAPQQYLVVA
EHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCHHHHHHHHCCCCEEEEEE
RGGKGGRGNARFATSTLQVPRIAEKGVEGEVKNLKLILKIVADVGLIGYPNVGKSTLISR
ECCCCCCCCCEEEECEECCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
ISNAKVEIADYPFTTIVPNLGVVKVDTDYSFVVADIPGLIEGAHLGKGLGDQFLRHIERC
HCCCEEEEECCCHHHHCCCCCEEEECCCCEEEEECCCCHHHHHHHCCCHHHHHHHHHHHH
SVLVHLIDISCFERDDPVEDYINIRKELESFSHILLKKKEIIVANKIDAVDKDTLEKRLT
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHH
DFKNRTGKDIFPISAYTGENIQELITMVWSHISKEKIEQQKFFQKRLKSNVTEKIKIQPV
HHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
NYEPDPFIKINVVKLDNETFEVVGDGIEKLLSRYDIHQKDSRLLILNTLEKNGLNKILRN
CCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHH
AGVKEGDTVYIGNFSFEYIP
CCCCCCCEEEEECEEEEECC
>Mature Secondary Structure
MIGDFVDEVNIKVIAGKGGDGAVSFRREKFVEKGGPDGGDGGDGGSIIIKSTLNKNTLVD
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCEEE
FKYKKIFRAENGENGKNKNKAGKAGEDVLIEVPVGTCIYDLETNELLSDLKAPQQYLVVA
EHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCHHHHHHHHCCCCEEEEEE
RGGKGGRGNARFATSTLQVPRIAEKGVEGEVKNLKLILKIVADVGLIGYPNVGKSTLISR
ECCCCCCCCCEEEECEECCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
ISNAKVEIADYPFTTIVPNLGVVKVDTDYSFVVADIPGLIEGAHLGKGLGDQFLRHIERC
HCCCEEEEECCCHHHHCCCCCEEEECCCCEEEEECCCCHHHHHHHCCCHHHHHHHHHHHH
SVLVHLIDISCFERDDPVEDYINIRKELESFSHILLKKKEIIVANKIDAVDKDTLEKRLT
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHH
DFKNRTGKDIFPISAYTGENIQELITMVWSHISKEKIEQQKFFQKRLKSNVTEKIKIQPV
HHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
NYEPDPFIKINVVKLDNETFEVVGDGIEKLLSRYDIHQKDSRLLILNTLEKNGLNKILRN
CCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHH
AGVKEGDTVYIGNFSFEYIP
CCCCCCCEEEEECEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA