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The map label for this gene is ccpA [H]

Identifier: 160902416

GI number: 160902416

Start: 1009942

End: 1010967

Strand: Direct

Name: ccpA [H]

Synonym: Pmob_0952

Alternate gene names: 160902416

Gene position: 1009942-1010967 (Clockwise)

Preceding gene: 160902412

Following gene: 160902417

Centisome position: 46.55

GC content: 32.46

Gene sequence:

>1026_bases
ATGCCACCAAAGAGAAACAAAAATTCTCGAATAACTATTGAAGATATAGCACAGATCGCACAAGTCTCTAAAGCTACTGT
TTCTTATGTGATCAACGATAAACCTGGTGTAAGTGAACCAGTTAGAAATAAAATAAAAAATATAATTGAGGAAACTAATT
ATTTCCCTAATTCTGCAGCAAGAGGTTTAGCAGGTGAAAAAACAAATTTTGTTGGTTTAGTTATCCCTGATATTTCTGAT
ATGTTTTATGCAAATATTATTAGAGGAGTAGAAAAAACTTTAAATAAAAAAGAATATCTTCTCAATCTATTTACCACACA
CGCAAGACCAGAAAGAGAGCAACAAGTAGTTCGACTGTTGAATAAAAGTATGGTTGACGGATTAATTATAATGGCTTATT
TTATTACTGATAATTTCATACAATCTTTGAAAGAAAGAGAGATCCCTTTTGTCTTCATCGATTACCCACCAAAAGATGAA
GATATTTATTCCGTAATGGTTGACAACGAAAATGGTGCTTTTGAGGCGACAGAATATTTGATAAAACTTGGGCATAAAAA
AATAGCGTTTTTAGAAGGTCCAGAAGTTGCGTGGGATTCAAAGGCACGATTCAAAGGTTATTTAAAGGCATTAGAAACTC
ATGGGATCAAATTCAACCCAGAATTGGTTGAAAATGGTAATTTTACAAAAGAGGAGGGATATACCGCTACAAAAAGGTTG
TTAGAAAAAGGAGAAAAATTCACAGCTGTCTTTTCTTCGAACGATCAAATGGCTATAGGGGCAATAAGGGCTTTAAAAGA
AAGTGGGTACAAAATTCCAACAGATGTCTCTATTGTGGGTTTTGATAACATCGAGGCAAGTTCTATAATAGAACCCCCTC
TAACAACTGTTTCACAGCCTATATATGAAATGGGTAAAAAGGCTGTAGATATAATAACAGCTTTGATAAATGGAGAAACA
ATAGAAGAAAAAAGATATATGTTAAAAACAAAATTAATTGAAAGACATTCTTGTACAAAAATATAA

Upstream 100 bases:

>100_bases
AATCTCATTTAATCGGATTTTTATTTTAAGAATATAAGAGTTATAATATGAATAGTTAAGCGGTTAAGTACTCTTATAAT
CAAATATTGGAGGAAAAACA

Downstream 100 bases:

>100_bases
ATTTTTTAGAGATAACTTAACCGATTAAGTAATTATAGATAGAGCTTTCAAGAGACACTTGAGAAATAATATGAGAGGTT
ACTAATAGGTAAATTCCCAA

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Glucose-resistance amylase regulator [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MPPKRNKNSRITIEDIAQIAQVSKATVSYVINDKPGVSEPVRNKIKNIIEETNYFPNSAARGLAGEKTNFVGLVIPDISD
MFYANIIRGVEKTLNKKEYLLNLFTTHARPEREQQVVRLLNKSMVDGLIIMAYFITDNFIQSLKEREIPFVFIDYPPKDE
DIYSVMVDNENGAFEATEYLIKLGHKKIAFLEGPEVAWDSKARFKGYLKALETHGIKFNPELVENGNFTKEEGYTATKRL
LEKGEKFTAVFSSNDQMAIGAIRALKESGYKIPTDVSIVGFDNIEASSIIEPPLTTVSQPIYEMGKKAVDIITALINGET
IEEKRYMLKTKLIERHSCTKI

Sequences:

>Translated_341_residues
MPPKRNKNSRITIEDIAQIAQVSKATVSYVINDKPGVSEPVRNKIKNIIEETNYFPNSAARGLAGEKTNFVGLVIPDISD
MFYANIIRGVEKTLNKKEYLLNLFTTHARPEREQQVVRLLNKSMVDGLIIMAYFITDNFIQSLKEREIPFVFIDYPPKDE
DIYSVMVDNENGAFEATEYLIKLGHKKIAFLEGPEVAWDSKARFKGYLKALETHGIKFNPELVENGNFTKEEGYTATKRL
LEKGEKFTAVFSSNDQMAIGAIRALKESGYKIPTDVSIVGFDNIEASSIIEPPLTTVSQPIYEMGKKAVDIITALINGET
IEEKRYMLKTKLIERHSCTKI
>Mature_340_residues
PPKRNKNSRITIEDIAQIAQVSKATVSYVINDKPGVSEPVRNKIKNIIEETNYFPNSAARGLAGEKTNFVGLVIPDISDM
FYANIIRGVEKTLNKKEYLLNLFTTHARPEREQQVVRLLNKSMVDGLIIMAYFITDNFIQSLKEREIPFVFIDYPPKDED
IYSVMVDNENGAFEATEYLIKLGHKKIAFLEGPEVAWDSKARFKGYLKALETHGIKFNPELVENGNFTKEEGYTATKRLL
EKGEKFTAVFSSNDQMAIGAIRALKESGYKIPTDVSIVGFDNIEASSIIEPPLTTVSQPIYEMGKKAVDIITALINGETI
EEKRYMLKTKLIERHSCTKI

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (AmyE) and the acetyl-coenzyme A synthetase (AcsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=336, Percent_Identity=32.7380952380952, Blast_Score=207, Evalue=5e-55,
Organism=Escherichia coli, GI1790194, Length=328, Percent_Identity=33.5365853658537, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1787948, Length=328, Percent_Identity=33.8414634146341, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1789202, Length=328, Percent_Identity=33.8414634146341, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1789068, Length=329, Percent_Identity=31.6109422492401, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1788474, Length=327, Percent_Identity=30.2752293577982, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1786540, Length=328, Percent_Identity=30.4878048780488, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1787580, Length=315, Percent_Identity=29.2063492063492, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1787906, Length=337, Percent_Identity=28.486646884273, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI48994940, Length=319, Percent_Identity=27.8996865203762, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790715, Length=316, Percent_Identity=27.8481012658228, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1786268, Length=324, Percent_Identity=25, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1789456, Length=319, Percent_Identity=27.5862068965517, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790689, Length=315, Percent_Identity=22.5396825396825, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1790192, Length=277, Percent_Identity=27.0758122743682, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38543; Mature: 38412

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPKRNKNSRITIEDIAQIAQVSKATVSYVINDKPGVSEPVRNKIKNIIEETNYFPNSAA
CCCCCCCCCEEEHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHH
RGLAGEKTNFVGLVIPDISDMFYANIIRGVEKTLNKKEYLLNLFTTHARPEREQQVVRLL
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
NKSMVDGLIIMAYFITDNFIQSLKEREIPFVFIDYPPKDEDIYSVMVDNENGAFEATEYL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCHHHHHHH
IKLGHKKIAFLEGPEVAWDSKARFKGYLKALETHGIKFNPELVENGNFTKEEGYTATKRL
HHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCHHHHHH
LEKGEKFTAVFSSNDQMAIGAIRALKESGYKIPTDVSIVGFDNIEASSIIEPPLTTVSQP
HHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHCCCCCHHHHHHH
IYEMGKKAVDIITALINGETIEEKRYMLKTKLIERHSCTKI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PPKRNKNSRITIEDIAQIAQVSKATVSYVINDKPGVSEPVRNKIKNIIEETNYFPNSAA
CCCCCCCCEEEHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHH
RGLAGEKTNFVGLVIPDISDMFYANIIRGVEKTLNKKEYLLNLFTTHARPEREQQVVRLL
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
NKSMVDGLIIMAYFITDNFIQSLKEREIPFVFIDYPPKDEDIYSVMVDNENGAFEATEYL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCHHHHHHH
IKLGHKKIAFLEGPEVAWDSKARFKGYLKALETHGIKFNPELVENGNFTKEEGYTATKRL
HHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCHHHHHH
LEKGEKFTAVFSSNDQMAIGAIRALKESGYKIPTDVSIVGFDNIEASSIIEPPLTTVSQP
HHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHCCCCCHHHHHHH
IYEMGKKAVDIITALINGETIEEKRYMLKTKLIERHSCTKI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1904524; 9387221; 9384377 [H]