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The map label for this gene is regA [H]

Identifier: 160902384

GI number: 160902384

Start: 972884

End: 973867

Strand: Direct

Name: regA [H]

Synonym: Pmob_0919

Alternate gene names: 160902384

Gene position: 972884-973867 (Clockwise)

Preceding gene: 160902383

Following gene: 160902385

Centisome position: 44.84

GC content: 33.64

Gene sequence:

>984_bases
ATGAATAAACAAATAACCATTAAAGATATAGCAAAAGAAGCGGGGGTTTCCATATCAACTGTTTCAAGGGTAATAAACAG
TTCCTTACCGGTAAAAAAAGAAACTAAAGAAAAAGTTTTAAAGGCAATTGAAAAGTTGAATTATTATCCCGATTCTCTCG
CCAGGAGTTTAAGAGTTGGATACACCAAGACAATAGGTATTATCATTCCAAATATTGCCAACCCCTTTTTTGCAACTATA
GTAAGAGGAGCAGAAGATTTTCTAAGATCAAAAGGCTTTTCTTTGATTATATGCAATTCGGATAACAACATTTCTGAAGA
AAAAAAATTATTTAAAACATTAATCGAAAAGAAAGTCGATGGGATTTTGTACTCAGGTATAGGTGACCATGTTGAAAGTC
TCATCAATAGAAATGTAAAAACCGTTTTCATAGACAGGATCATTAAAAACAATGAATTTTCTTACGTTTGTTCAAACAAC
TACAATGGAATGCATAAATTACTTGAATATCTATACAATTCAAATCACAGAAAATTCATATTTATAAGCGGCAAGAGAGA
AATATTCAGTGCAGCTGAAAGATTAAGAGCCTTCCAAGATTTTGCAAATGAATACAAGATAGATTACAAAATATTTGAGG
GAGAGTACACTCATGAATCGGGGATTTCGGTGGCTAAAAAGATTAAAAGTCTTCCCGACGTTGTGGTATGTGCAAATGAC
TTGTTGGCTTATGGAGTTATAGAACATTTTAAAACAAATGGTTTGAAAGTGCCAAAAGATGTAAGCGTCACTGGCTACGA
CGACATCGCGTTTAGTAAAATGTTCTCACCACCTTTAACCACTGTGAAACAACCTATGTATGAAATGGGAAAAACGGCCG
GAGAAATGATCTTTACAATACTTTCAAAAAAAATCGATCACATTCCTGTGAAACAGTTTGAGAACGAGATAATAATTCGA
GAAAGTACGAGGGGGAGAAACTAA

Upstream 100 bases:

>100_bases
TCCCCCATAATCAAGTTTGCAATTTAAATTATTTAGGGATATACTATGAATAAGCAGTTCCGAAAACGTTTGCATAATAA
TTGTAACAAGGTGGTTTTTT

Downstream 100 bases:

>100_bases
TTTGAAAAAGCAAGGCATATTTAATTCTCAGATATCATATTTTGTTGCATCGATGGGGCATAAAGATATGTTAAGTATAG
TTGACATGGGTTATCCAATA

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MNKQITIKDIAKEAGVSISTVSRVINSSLPVKKETKEKVLKAIEKLNYYPDSLARSLRVGYTKTIGIIIPNIANPFFATI
VRGAEDFLRSKGFSLIICNSDNNISEEKKLFKTLIEKKVDGILYSGIGDHVESLINRNVKTVFIDRIIKNNEFSYVCSNN
YNGMHKLLEYLYNSNHRKFIFISGKREIFSAAERLRAFQDFANEYKIDYKIFEGEYTHESGISVAKKIKSLPDVVVCAND
LLAYGVIEHFKTNGLKVPKDVSVTGYDDIAFSKMFSPPLTTVKQPMYEMGKTAGEMIFTILSKKIDHIPVKQFENEIIIR
ESTRGRN

Sequences:

>Translated_327_residues
MNKQITIKDIAKEAGVSISTVSRVINSSLPVKKETKEKVLKAIEKLNYYPDSLARSLRVGYTKTIGIIIPNIANPFFATI
VRGAEDFLRSKGFSLIICNSDNNISEEKKLFKTLIEKKVDGILYSGIGDHVESLINRNVKTVFIDRIIKNNEFSYVCSNN
YNGMHKLLEYLYNSNHRKFIFISGKREIFSAAERLRAFQDFANEYKIDYKIFEGEYTHESGISVAKKIKSLPDVVVCAND
LLAYGVIEHFKTNGLKVPKDVSVTGYDDIAFSKMFSPPLTTVKQPMYEMGKTAGEMIFTILSKKIDHIPVKQFENEIIIR
ESTRGRN
>Mature_327_residues
MNKQITIKDIAKEAGVSISTVSRVINSSLPVKKETKEKVLKAIEKLNYYPDSLARSLRVGYTKTIGIIIPNIANPFFATI
VRGAEDFLRSKGFSLIICNSDNNISEEKKLFKTLIEKKVDGILYSGIGDHVESLINRNVKTVFIDRIIKNNEFSYVCSNN
YNGMHKLLEYLYNSNHRKFIFISGKREIFSAAERLRAFQDFANEYKIDYKIFEGEYTHESGISVAKKIKSLPDVVVCAND
LLAYGVIEHFKTNGLKVPKDVSVTGYDDIAFSKMFSPPLTTVKQPMYEMGKTAGEMIFTILSKKIDHIPVKQFENEIIIR
ESTRGRN

Specific function: Involved in the regulation of amylase production [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=305, Percent_Identity=34.4262295081967, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1790194, Length=299, Percent_Identity=33.7792642140468, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1790369, Length=331, Percent_Identity=30.5135951661631, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1788474, Length=331, Percent_Identity=27.4924471299094, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789068, Length=335, Percent_Identity=28.955223880597, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1789202, Length=294, Percent_Identity=29.5918367346939, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787580, Length=316, Percent_Identity=27.2151898734177, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786540, Length=307, Percent_Identity=26.7100977198697, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787906, Length=324, Percent_Identity=23.4567901234568, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789456, Length=307, Percent_Identity=28.3387622149837, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790715, Length=314, Percent_Identity=24.8407643312102, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786268, Length=313, Percent_Identity=23.961661341853, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI48994940, Length=304, Percent_Identity=21.0526315789474, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790689, Length=299, Percent_Identity=24.4147157190635, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37137; Mature: 37137

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQITIKDIAKEAGVSISTVSRVINSSLPVKKETKEKVLKAIEKLNYYPDSLARSLRVG
CCCCEEHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCC
YTKTIGIIIPNIANPFFATIVRGAEDFLRSKGFSLIICNSDNNISEEKKLFKTLIEKKVD
CCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
GILYSGIGDHVESLINRNVKTVFIDRIIKNNEFSYVCSNNYNGMHKLLEYLYNSNHRKFI
HHHHCCHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEE
FISGKREIFSAAERLRAFQDFANEYKIDYKIFEGEYTHESGISVAKKIKSLPDVVVCAND
EEECCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHH
LLAYGVIEHFKTNGLKVPKDVSVTGYDDIAFSKMFSPPLTTVKQPMYEMGKTAGEMIFTI
HHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LSKKIDHIPVKQFENEIIIRESTRGRN
HHHHHCCCCHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MNKQITIKDIAKEAGVSISTVSRVINSSLPVKKETKEKVLKAIEKLNYYPDSLARSLRVG
CCCCEEHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCC
YTKTIGIIIPNIANPFFATIVRGAEDFLRSKGFSLIICNSDNNISEEKKLFKTLIEKKVD
CCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
GILYSGIGDHVESLINRNVKTVFIDRIIKNNEFSYVCSNNYNGMHKLLEYLYNSNHRKFI
HHHHCCHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEE
FISGKREIFSAAERLRAFQDFANEYKIDYKIFEGEYTHESGISVAKKIKSLPDVVVCAND
EEECCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHH
LLAYGVIEHFKTNGLKVPKDVSVTGYDDIAFSKMFSPPLTTVKQPMYEMGKTAGEMIFTI
HHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LSKKIDHIPVKQFENEIIIRESTRGRN
HHHHHCCCCHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7539689 [H]