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The map label for this gene is pdp [H]

Identifier: 160902342

GI number: 160902342

Start: 931677

End: 933002

Strand: Direct

Name: pdp [H]

Synonym: Pmob_0877

Alternate gene names: 160902342

Gene position: 931677-933002 (Clockwise)

Preceding gene: 160902341

Following gene: 160902343

Centisome position: 42.94

GC content: 34.31

Gene sequence:

>1326_bases
TTGAGAGCATACGATATTATAAAAAATAAAAGAGATGCTAAAGAAAATACAAGAGAAGAAATAGAATTTATGATCAATGG
CTATTTAGAAAACCGTATTCCAGACTATCAAGTTTCTTCCTGGTTAATGGCTATTTTCTTCAACCATTTAACAGAGGAAG
AAAGTTATAATCTAACGGATGTAATGCTTAAAAGTGGAGATATTATAGACTTATCAAGGATCACAGGTAAAAAAATCGAC
AAACACTCTACTGGAGGCGTTGGTGACAAAACTACAATAGCCATAGCACCTATGGTTGCTTCATTAGGGGTTAAAATAGC
CAAATTATCGGGCAGATCTTTAGGGCACACTGGAGGAACTATAGACAAGCTTGAATCTATTCCTGGTTTTAAAACCTCTC
TAACCACTGAAGAATTCTTTGAAATAGCGAACAACGTAGGGATTGTTGTGGCTGGACAGACTGGAAATATTGCCCCAGCA
GATAAAAAATTGTATTCCTTAAGGGATTCTACCGCAACTGTTGAGGAATTATCCTTAATAGCTTCAAGTATAATGAGTAA
AAAACTCGCCATAAATAGTGACGGAATCCTTTTGGACATCAAAGTGGGTTCAGGGGCGTTCATGAAAAACATTGAAGATG
CCAAAGAGTTAGGTAGAATCATGCTAAAAATCGCAAAAAGATACGATAAAAATACTGTTGCTTTAATTACCAATATGGAT
CAACCTTTGGGAGATAACGTTGGAAACGCTTTGGAGGTAATGGAAGCAATAGATACAGTCAAAGGAAAAGGCCCAAAAGA
TTTTTCTGAGTTATGTTTAGAAATCTCTTCTTATATGGCTTCCTTATCTGGTATAATAACCTATGAAGAAGCGAAGAAAA
AATTAATAGAAAACATAGAACGCGGTATAGTAAAAGAAAAAATGAAAGAATGGATAAAAGCTCAGGGCGGAAAAGAAGAA
GTAGTTGATGATCCCAGTAAGTATCTTAATATATCCTCAAAAACTTTAGAATTCAAGGCAAAAGAACAAGGGTATATAAC
CTTTATTGATACCGAAAAAATAGGTTTAGCATCAATGGTATTAGGAGCCGGCAGACAAAAAAAAGAAGATATTATCGATA
AAAGTGTTGGTTTAACAATTAACAAAAAACTTGGTGATAAAGTTGAAGAAGGGGAGACAATAGCTAAGTTGTTTGTCAGT
GACAACAGCGACGTTGATGCCTCTCTAAACCTTTTAAATGCTGCTTACAACATTAGTAAAGAAAAGCCTAAAAACATAAA
TAAAAATGTAATTCTTGATGTCTTATTTTCCAATGAGAAAAGTTGA

Upstream 100 bases:

>100_bases
ACCACAATGCAAGAATATATTTAGACAGTGAAGAAAACAACGGTACATTGTTTCAAGTCATCCTTCCTATCAAAACAAAT
AATGAAACGGAGGTTTAAAG

Downstream 100 bases:

>100_bases
TTGGATGGAGGATCATTCATTGATGAAAAAGCTTATCTTTCTCTTCTTGCTAATAATTCTAGCAATAAATTTATTTTCTG
AAGAAGCTATTTTTATATCT

Product: pyrimidine-nucleoside phosphorylase

Products: NA

Alternate protein names: PYNP [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MRAYDIIKNKRDAKENTREEIEFMINGYLENRIPDYQVSSWLMAIFFNHLTEEESYNLTDVMLKSGDIIDLSRITGKKID
KHSTGGVGDKTTIAIAPMVASLGVKIAKLSGRSLGHTGGTIDKLESIPGFKTSLTTEEFFEIANNVGIVVAGQTGNIAPA
DKKLYSLRDSTATVEELSLIASSIMSKKLAINSDGILLDIKVGSGAFMKNIEDAKELGRIMLKIAKRYDKNTVALITNMD
QPLGDNVGNALEVMEAIDTVKGKGPKDFSELCLEISSYMASLSGIITYEEAKKKLIENIERGIVKEKMKEWIKAQGGKEE
VVDDPSKYLNISSKTLEFKAKEQGYITFIDTEKIGLASMVLGAGRQKKEDIIDKSVGLTINKKLGDKVEEGETIAKLFVS
DNSDVDASLNLLNAAYNISKEKPKNINKNVILDVLFSNEKS

Sequences:

>Translated_441_residues
MRAYDIIKNKRDAKENTREEIEFMINGYLENRIPDYQVSSWLMAIFFNHLTEEESYNLTDVMLKSGDIIDLSRITGKKID
KHSTGGVGDKTTIAIAPMVASLGVKIAKLSGRSLGHTGGTIDKLESIPGFKTSLTTEEFFEIANNVGIVVAGQTGNIAPA
DKKLYSLRDSTATVEELSLIASSIMSKKLAINSDGILLDIKVGSGAFMKNIEDAKELGRIMLKIAKRYDKNTVALITNMD
QPLGDNVGNALEVMEAIDTVKGKGPKDFSELCLEISSYMASLSGIITYEEAKKKLIENIERGIVKEKMKEWIKAQGGKEE
VVDDPSKYLNISSKTLEFKAKEQGYITFIDTEKIGLASMVLGAGRQKKEDIIDKSVGLTINKKLGDKVEEGETIAKLFVS
DNSDVDASLNLLNAAYNISKEKPKNINKNVILDVLFSNEKS
>Mature_441_residues
MRAYDIIKNKRDAKENTREEIEFMINGYLENRIPDYQVSSWLMAIFFNHLTEEESYNLTDVMLKSGDIIDLSRITGKKID
KHSTGGVGDKTTIAIAPMVASLGVKIAKLSGRSLGHTGGTIDKLESIPGFKTSLTTEEFFEIANNVGIVVAGQTGNIAPA
DKKLYSLRDSTATVEELSLIASSIMSKKLAINSDGILLDIKVGSGAFMKNIEDAKELGRIMLKIAKRYDKNTVALITNMD
QPLGDNVGNALEVMEAIDTVKGKGPKDFSELCLEISSYMASLSGIITYEEAKKKLIENIERGIVKEKMKEWIKAQGGKEE
VVDDPSKYLNISSKTLEFKAKEQGYITFIDTEKIGLASMVLGAGRQKKEDIIDKSVGLTINKKLGDKVEEGETIAKLFVS
DNSDVDASLNLLNAAYNISKEKPKNINKNVILDVLFSNEKS

Specific function: The Enzymes Which Catalyze The Reversible Phosphorolysis Of Pyrimidine Nucleosides Are Involved In The Degradation Of These Compounds And In Their Utilization As Carbon And Energy Sources, Or In The Rescue Of Pyrimidine Bases For Nucleotide Synthesis. [C

COG id: COG0213

COG function: function code F; Thymidine phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI166158925, Length=403, Percent_Identity=32.258064516129, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI4503445, Length=403, Percent_Identity=32.258064516129, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI166158922, Length=403, Percent_Identity=32.258064516129, Blast_Score=214, Evalue=1e-55,
Organism=Escherichia coli, GI1790842, Length=411, Percent_Identity=39.9026763990268, Blast_Score=294, Evalue=7e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR013102
- InterPro:   IPR018090
- InterPro:   IPR000053
- InterPro:   IPR017872 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; PF07831 PYNP_C [H]

EC number: =2.4.2.2 [H]

Molecular weight: Translated: 48470; Mature: 48470

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAYDIIKNKRDAKENTREEIEFMINGYLENRIPDYQVSSWLMAIFFNHLTEEESYNLTD
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
VMLKSGDIIDLSRITGKKIDKHSTGGVGDKTTIAIAPMVASLGVKIAKLSGRSLGHTGGT
HHCCCCCEEEEHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCEEEEECCCCCCCCCCC
IDKLESIPGFKTSLTTEEFFEIANNVGIVVAGQTGNIAPADKKLYSLRDSTATVEELSLI
HHHHHCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHH
ASSIMSKKLAINSDGILLDIKVGSGAFMKNIEDAKELGRIMLKIAKRYDKNTVALITNMD
HHHHHHHHHEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
QPLGDNVGNALEVMEAIDTVKGKGPKDFSELCLEISSYMASLSGIITYEEAKKKLIENIE
CCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHH
RGIVKEKMKEWIKAQGGKEEVVDDPSKYLNISSKTLEFKAKEQGYITFIDTEKIGLASMV
HHHHHHHHHHHHHCCCCCHHHHCCHHHHEECCCCEEEEEECCCCCEEEEECCCCCHHHHH
LGAGRQKKEDIIDKSVGLTINKKLGDKVEEGETIAKLFVSDNSDVDASLNLLNAAYNISK
HCCCCCHHHHHHHHHCCEEEEHHHCCCHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCC
EKPKNINKNVILDVLFSNEKS
CCCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MRAYDIIKNKRDAKENTREEIEFMINGYLENRIPDYQVSSWLMAIFFNHLTEEESYNLTD
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
VMLKSGDIIDLSRITGKKIDKHSTGGVGDKTTIAIAPMVASLGVKIAKLSGRSLGHTGGT
HHCCCCCEEEEHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCEEEEECCCCCCCCCCC
IDKLESIPGFKTSLTTEEFFEIANNVGIVVAGQTGNIAPADKKLYSLRDSTATVEELSLI
HHHHHCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHH
ASSIMSKKLAINSDGILLDIKVGSGAFMKNIEDAKELGRIMLKIAKRYDKNTVALITNMD
HHHHHHHHHEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
QPLGDNVGNALEVMEAIDTVKGKGPKDFSELCLEISSYMASLSGIITYEEAKKKLIENIE
CCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHH
RGIVKEKMKEWIKAQGGKEEVVDDPSKYLNISSKTLEFKAKEQGYITFIDTEKIGLASMV
HHHHHHHHHHHHHCCCCCHHHHCCHHHHEECCCCEEEEEECCCCCEEEEECCCCCHHHHH
LGAGRQKKEDIIDKSVGLTINKKLGDKVEEGETIAKLFVSDNSDVDASLNLLNAAYNISK
HCCCCCHHHHHHHHHCCEEEEHHHCCCHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCC
EKPKNINKNVILDVLFSNEKS
CCCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8987664; 9817849 [H]