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The map label for this gene is yycF [H]

Identifier: 160902340

GI number: 160902340

Start: 929593

End: 930321

Strand: Direct

Name: yycF [H]

Synonym: Pmob_0875

Alternate gene names: 160902340

Gene position: 929593-930321 (Clockwise)

Preceding gene: 160902339

Following gene: 160902341

Centisome position: 42.85

GC content: 36.35

Gene sequence:

>729_bases
GTGGCAAAAAAAAGTATTATGATAGTAGAAGACGATCCGGCGATCTCTGAAATGTTATCTTTGAACTTGACCAAAGAAGG
TTACGAAGTAATAACGGCTGTGTCTGCTGATGAGGCTTTAAAGAAATTAGAGGAAAAAGATACCGACTTTTTCATAGTGG
ATATTATGTTACCAGGTTCAATGGATGGATTTGATTTAATTAGAATCTTGAAATCCAGCGAAGATTATCGCAATACGCCC
GTACTCATATTGAGTGCCAAAGATGATGCTGCTGATAAAGTAGCTGGGTTAGAACTTGGTAGCGATGATTATGTCACTAA
ACCTTTTAATGTAAGAGAACTAATTGCAAGAATTAAAAGCATATTTAGGAGACAAGCTGCATCAGCTCAAATGAAAGAAG
AAGGACCCAAAAAAATTACAGCTAAAGATTTAATTATCGACACTGAAAGATTAGAAGTTTGGGTAGGGGGAAATCCAGTC
AGCCTTACCCCGTTGGAGTTCGATTTGTTAGTTTTTCTTGCTAAAAATGAAGGAAAAGTCTTTAGTCGAGATGTATTGTT
GGATAAATTGTGGGGTTATGACTACTACGGAGATACAAGAACAGTAGACGTTCATATCAGAAGGTTGAGAACAAAGATCG
AAGAAGATCCTTCTAATCCAAAATACATAATTACAGTAAGAGGGAAAGGATACAAATTCAGAGATCCTGGAAAGGAAAGA
AACTACTAA

Upstream 100 bases:

>100_bases
AGTATAAATTTGTCAGGACAAATTTCTGAGCGTTACACATGAAGATGAGTCTTAGTTAAATAAGTTAACCAAAAAAATAT
CCCAAAGGGGGGAAAGAAAA

Downstream 100 bases:

>100_bases
ATATTCAATGGCAGAGGGTAATACCTCTGCCTTTTTTCCAATTGGATTTTATTAATAAACTAGGTGAAAATATTGGTCAA
TATATATATTATCGTTATTT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MAKKSIMIVEDDPAISEMLSLNLTKEGYEVITAVSADEALKKLEEKDTDFFIVDIMLPGSMDGFDLIRILKSSEDYRNTP
VLILSAKDDAADKVAGLELGSDDYVTKPFNVRELIARIKSIFRRQAASAQMKEEGPKKITAKDLIIDTERLEVWVGGNPV
SLTPLEFDLLVFLAKNEGKVFSRDVLLDKLWGYDYYGDTRTVDVHIRRLRTKIEEDPSNPKYIITVRGKGYKFRDPGKER
NY

Sequences:

>Translated_242_residues
MAKKSIMIVEDDPAISEMLSLNLTKEGYEVITAVSADEALKKLEEKDTDFFIVDIMLPGSMDGFDLIRILKSSEDYRNTP
VLILSAKDDAADKVAGLELGSDDYVTKPFNVRELIARIKSIFRRQAASAQMKEEGPKKITAKDLIIDTERLEVWVGGNPV
SLTPLEFDLLVFLAKNEGKVFSRDVLLDKLWGYDYYGDTRTVDVHIRRLRTKIEEDPSNPKYIITVRGKGYKFRDPGKER
NY
>Mature_241_residues
AKKSIMIVEDDPAISEMLSLNLTKEGYEVITAVSADEALKKLEEKDTDFFIVDIMLPGSMDGFDLIRILKSSEDYRNTPV
LILSAKDDAADKVAGLELGSDDYVTKPFNVRELIARIKSIFRRQAASAQMKEEGPKKITAKDLIIDTERLEVWVGGNPVS
LTPLEFDLLVFLAKNEGKVFSRDVLLDKLWGYDYYGDTRTVDVHIRRLRTKIEEDPSNPKYIITVRGKGYKFRDPGKERN
Y

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=39.4849785407725, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=36.7965367965368, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=36.3636363636364, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=34.3478260869565, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=35.8078602620087, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=37.5545851528384, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=35.8649789029536, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=34.6491228070175, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=34.2105263157895, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=35.5263157894737, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=34.9344978165939, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790860, Length=244, Percent_Identity=34.4262295081967, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=32.7586206896552, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=31.7796610169492, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790299, Length=139, Percent_Identity=30.2158273381295, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788550, Length=132, Percent_Identity=28.7878787878788, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27489; Mature: 27358

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKSIMIVEDDPAISEMLSLNLTKEGYEVITAVSADEALKKLEEKDTDFFIVDIMLPGS
CCCCCEEEEECCHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHCCCCEEEEEEEECCC
MDGFDLIRILKSSEDYRNTPVLILSAKDDAADKVAGLELGSDDYVTKPFNVRELIARIKS
CCHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHEECEEECCCCCEECCCCHHHHHHHHHH
IFRRQAASAQMKEEGPKKITAKDLIIDTERLEVWVGGNPVSLTPLEFDLLVFLAKNEGKV
HHHHHHHHHHHHHCCCCEEEHHHEEEEEEHEEEEECCCCEEECCEEEEEEEEEECCCCCE
FSRDVLLDKLWGYDYYGDTRTVDVHIRRLRTKIEEDPSNPKYIITVRGKGYKFRDPGKER
EHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCCCC
NY
CC
>Mature Secondary Structure 
AKKSIMIVEDDPAISEMLSLNLTKEGYEVITAVSADEALKKLEEKDTDFFIVDIMLPGS
CCCCEEEEECCHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHCCCCEEEEEEEECCC
MDGFDLIRILKSSEDYRNTPVLILSAKDDAADKVAGLELGSDDYVTKPFNVRELIARIKS
CCHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHEECEEECCCCCEECCCCHHHHHHHHHH
IFRRQAASAQMKEEGPKKITAKDLIIDTERLEVWVGGNPVSLTPLEFDLLVFLAKNEGKV
HHHHHHHHHHHHHCCCCEEEHHHEEEEEEHEEEEECCCCEEECCEEEEEEEEEECCCCCE
FSRDVLLDKLWGYDYYGDTRTVDVHIRRLRTKIEEDPSNPKYIITVRGKGYKFRDPGKER
EHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCCCC
NY
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]