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The map label for this gene is apeA [H]

Identifier: 160902207

GI number: 160902207

Start: 795355

End: 796773

Strand: Direct

Name: apeA [H]

Synonym: Pmob_0741

Alternate gene names: 160902207

Gene position: 795355-796773 (Clockwise)

Preceding gene: 160902205

Following gene: 160902208

Centisome position: 36.66

GC content: 37.84

Gene sequence:

>1419_bases
ATGGACCTAACAGAGTTAGAAAAAAGTTTAACTTTTCAAAAGAAAAGTGTATGGAGCAAAAGAAACAAAGAAGATATCGA
TAGGTATACTTCACAGTACAAGGATTTTATCAACTTTTCTAAAACTGAAAGAAAGGCAGCTACATACTCAGTGGAGCTCC
TTGAAAAAAACGGTTTCAAACCTCTTTCTCATTACGTGAACTTAGGAAAGATAGAGAAAGGGGATAAAGTTTACTTTGTA
AACAGAGATAAAGCGGTATTCGCTCTCAAGTACAACAATCCTTTGAAGGATGGTATCAACATAGTAGGTGCCCACATAGA
TTCGCCAAGGTTTGATTTGAAACCCGAGCCAATAGTGGAAGATGAGAATATTGCAATGGCAAAGACTCATTATTATGGTG
GAGTGAAGAAGTATCACTGGTTCAACATACCTCTTGAATTACATGGCGTAGTAATAAAAAGCGATGGAAGTAAAATAGAG
GTTTCCATAGGACAAGACGAAAACGATCCCGTATTTGTAATATCAGATTTACTGCCACATCTCGATAGAGATTTGGCTAA
TAAAAAGGTTTCGGAAGCATTTGAAGCCGAGAAAATGAATGTATTAGTTGGTACTACTGCTATTTCCTACGATGAAACCG
ATAAGATTAAAAATCCAGTTAAGTTAAATATCTTGAAGATTTTGAACGATAAATATGGAATCGTAGAAGAAGACTTAGTT
AGTGCTGAATTGGAAATCGTTCCTGCACTTCCTGCTAGAGATGTAGGATTGGATAAAAGCCTTTTAGCTTCCTACGGACA
CGACGATAGGGTCTGTGCCTACACAGGATTGACCGCTTTAATCGATGCTCAAACATCTGTAAAAAACCCGGCAGTTTTAC
TAGTCGACAAAGAAGAAATAGGTAGCGATGGAAATACAGGAGCAAAAAATCATTTCTGGATCTACGTTTTGAAGAAAATT
GCCGCTTTAGCAAAAGAAGAAGAACTACTTCAAAACATAGAAGAAATTCTCACCAATTCTACTTTGCTTTCAGCCGATGT
ATCAGCTGCTGTAGATCCAAATTACAAAGAAGCTCACGATCTATCCAACGCTCCAAAATTGGGTTACGGTATAACTCTTA
TGAAATACACAGGTTCAGGAGGCAAAGGAAGAACAAACGATGCAAATGCTGAATTAGTAGGAAAAGTTAGAAACCTTTTC
AACAAAGAAGGCATATCTTGGCAAATAGGAGAACTGGGAAAGGTAGACAGAGGCGGAGGAGGAACCATAGCCCTTTTCTT
TTCTGAAAAAGGTTTAGACGTTTTGGATGCTGGCGTGCCGCTTTTGGGGATGCACTCTCCGTATGAAGTGGCATCAAAAG
CGGATATATACGAAACTTATTTGGCATATAAAACTTTTTACGAAAAGTTTGGAAAATGA

Upstream 100 bases:

>100_bases
ACGGATTATTTGAGTATTCATAAATCAGAACTGTATGAAAAATTATTTAACTGTGCTTATTTTCAAAAAAATATGGTAAA
ATTTTATTGGAGGTGATCTA

Downstream 100 bases:

>100_bases
GAATTTTTGTAGGAAACTCTGCAAATGCAATGGAATTTTTTGATTTTGATTTAATATTATCAACCTCAGGTTGGTCTTTA
AACGACCAATCTGAGGTTAT

Product: putative aminopeptidase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MDLTELEKSLTFQKKSVWSKRNKEDIDRYTSQYKDFINFSKTERKAATYSVELLEKNGFKPLSHYVNLGKIEKGDKVYFV
NRDKAVFALKYNNPLKDGINIVGAHIDSPRFDLKPEPIVEDENIAMAKTHYYGGVKKYHWFNIPLELHGVVIKSDGSKIE
VSIGQDENDPVFVISDLLPHLDRDLANKKVSEAFEAEKMNVLVGTTAISYDETDKIKNPVKLNILKILNDKYGIVEEDLV
SAELEIVPALPARDVGLDKSLLASYGHDDRVCAYTGLTALIDAQTSVKNPAVLLVDKEEIGSDGNTGAKNHFWIYVLKKI
AALAKEEELLQNIEEILTNSTLLSADVSAAVDPNYKEAHDLSNAPKLGYGITLMKYTGSGGKGRTNDANAELVGKVRNLF
NKEGISWQIGELGKVDRGGGGTIALFFSEKGLDVLDAGVPLLGMHSPYEVASKADIYETYLAYKTFYEKFGK

Sequences:

>Translated_472_residues
MDLTELEKSLTFQKKSVWSKRNKEDIDRYTSQYKDFINFSKTERKAATYSVELLEKNGFKPLSHYVNLGKIEKGDKVYFV
NRDKAVFALKYNNPLKDGINIVGAHIDSPRFDLKPEPIVEDENIAMAKTHYYGGVKKYHWFNIPLELHGVVIKSDGSKIE
VSIGQDENDPVFVISDLLPHLDRDLANKKVSEAFEAEKMNVLVGTTAISYDETDKIKNPVKLNILKILNDKYGIVEEDLV
SAELEIVPALPARDVGLDKSLLASYGHDDRVCAYTGLTALIDAQTSVKNPAVLLVDKEEIGSDGNTGAKNHFWIYVLKKI
AALAKEEELLQNIEEILTNSTLLSADVSAAVDPNYKEAHDLSNAPKLGYGITLMKYTGSGGKGRTNDANAELVGKVRNLF
NKEGISWQIGELGKVDRGGGGTIALFFSEKGLDVLDAGVPLLGMHSPYEVASKADIYETYLAYKTFYEKFGK
>Mature_472_residues
MDLTELEKSLTFQKKSVWSKRNKEDIDRYTSQYKDFINFSKTERKAATYSVELLEKNGFKPLSHYVNLGKIEKGDKVYFV
NRDKAVFALKYNNPLKDGINIVGAHIDSPRFDLKPEPIVEDENIAMAKTHYYGGVKKYHWFNIPLELHGVVIKSDGSKIE
VSIGQDENDPVFVISDLLPHLDRDLANKKVSEAFEAEKMNVLVGTTAISYDETDKIKNPVKLNILKILNDKYGIVEEDLV
SAELEIVPALPARDVGLDKSLLASYGHDDRVCAYTGLTALIDAQTSVKNPAVLLVDKEEIGSDGNTGAKNHFWIYVLKKI
AALAKEEELLQNIEEILTNSTLLSADVSAAVDPNYKEAHDLSNAPKLGYGITLMKYTGSGGKGRTNDANAELVGKVRNLF
NKEGISWQIGELGKVDRGGGGTIALFFSEKGLDVLDAGVPLLGMHSPYEVASKADIYETYLAYKTFYEKFGK

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=475, Percent_Identity=26.7368421052632, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17552916, Length=472, Percent_Identity=26.0593220338983, Blast_Score=130, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321905, Length=495, Percent_Identity=27.0707070707071, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6322746, Length=483, Percent_Identity=24.4306418219462, Blast_Score=103, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022983
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 52429; Mature: 52429

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTELEKSLTFQKKSVWSKRNKEDIDRYTSQYKDFINFSKTERKAATYSVELLEKNGFK
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHEEEEEEECCCCCC
PLSHYVNLGKIEKGDKVYFVNRDKAVFALKYNNPLKDGINIVGAHIDSPRFDLKPEPIVE
HHHHHCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCC
DENIAMAKTHYYGGVKKYHWFNIPLELHGVVIKSDGSKIEVSIGQDENDPVFVISDLLPH
CCCEEEEEEEECCCCCEEEEEECCEEEEEEEEECCCCEEEEEECCCCCCCEEEHHHHHHH
LDRDLANKKVSEAFEAEKMNVLVGTTAISYDETDKIKNPVKLNILKILNDKYGIVEEDLV
HHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCHHHCCCCCEEEEEEECCCCCCCCHHHHH
SAELEIVPALPARDVGLDKSLLASYGHDDRVCAYTGLTALIDAQTSVKNPAVLLVDKEEI
CCEEEEEECCCCCCCCCCHHHHHHCCCCCCEEEEECCHHEEECCCCCCCCEEEEEEHHHC
GSDGNTGAKNHFWIYVLKKIAALAKEEELLQNIEEILTNSTLLSADVSAAVDPNYKEAHD
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHCCCCCCHHHHC
LSNAPKLGYGITLMKYTGSGGKGRTNDANAELVGKVRNLFNKEGISWQIGELGKVDRGGG
CCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
GTIALFFSEKGLDVLDAGVPLLGMHSPYEVASKADIYETYLAYKTFYEKFGK
CEEEEEEECCCCCHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLTELEKSLTFQKKSVWSKRNKEDIDRYTSQYKDFINFSKTERKAATYSVELLEKNGFK
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHEEEEEEECCCCCC
PLSHYVNLGKIEKGDKVYFVNRDKAVFALKYNNPLKDGINIVGAHIDSPRFDLKPEPIVE
HHHHHCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCC
DENIAMAKTHYYGGVKKYHWFNIPLELHGVVIKSDGSKIEVSIGQDENDPVFVISDLLPH
CCCEEEEEEEECCCCCEEEEEECCEEEEEEEEECCCCEEEEEECCCCCCCEEEHHHHHHH
LDRDLANKKVSEAFEAEKMNVLVGTTAISYDETDKIKNPVKLNILKILNDKYGIVEEDLV
HHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCHHHCCCCCEEEEEEECCCCCCCCHHHHH
SAELEIVPALPARDVGLDKSLLASYGHDDRVCAYTGLTALIDAQTSVKNPAVLLVDKEEI
CCEEEEEECCCCCCCCCCHHHHHHCCCCCCEEEEECCHHEEECCCCCCCCEEEEEEHHHC
GSDGNTGAKNHFWIYVLKKIAALAKEEELLQNIEEILTNSTLLSADVSAAVDPNYKEAHD
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHCCCCCCHHHHC
LSNAPKLGYGITLMKYTGSGGKGRTNDANAELVGKVRNLFNKEGISWQIGELGKVDRGGG
CCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
GTIALFFSEKGLDVLDAGVPLLGMHSPYEVASKADIYETYLAYKTFYEKFGK
CEEEEEEECCCCCHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]