Click here to switch to the map view.

The map label for this gene is lepB2 [H]

Identifier: 160901810

GI number: 160901810

Start: 348337

End: 349302

Strand: Direct

Name: lepB2 [H]

Synonym: Pmob_0326

Alternate gene names: 160901810

Gene position: 348337-349302 (Clockwise)

Preceding gene: 160901809

Following gene: 160901811

Centisome position: 16.06

GC content: 33.02

Gene sequence:

>966_bases
TTGAAAGAGGCTACTAAGAAGAAAATTAAAGATGAAACCTTAGATTGGATTTACGCCATAATATATGCACTGATATTTGG
AACAATTATCAGACTCTACGTGTTTGAAACAATGATGGTTCCAACTCCTTCTATGGTTCCAACGATCCAAGTATACGACA
GGTTGTTTGTAGAAAAAGTTACCTATGAATTTGCCGAACCAAATAGAGGCTCAATAGTGGTCTTTTGGACACCTTTTGTG
GACATTAGGGCCCAACAACAGTTACGTACTTTTGATAGGTTTATGGATTTTTTTGCTCCAGCACAATTTGAAGGTCATGT
AAAATACGTTAAGAGATTGGTGGGGAAACCGGGTGATACCTTAAGACTGGTACCAGTTGAAGAAAAGTTTTGGGAAGATA
TTAAAAACGGAGAAATTCAAAATACTCCCGAGTGGTTAGATTTTATTATTGATTATTATGAAAGTGTAGATTATATTCCA
ACCCAGATAAAAAACAAGGTTTCAAAACTAGAAATAAACGGCGAAATACTACCTGAATTTGAAAATATTTATTATTTAAG
AGATGCAATATTTGAAGATCCTAAATTTTTTGATTATATAGCCTATCCCGATCAATACCGTTATGAAATTGCTACATCTG
ATTTATTTTTTATGTATAAAGATAACTTCACAGGCAGATTAATACCAGCTAAACCCACTATTGAATGGTACAAAGAAATG
AGAGATACACTCTTATTTACCAATTTTTATGAAAACGAACTTTCAAAATTGGACTTGACTTCTTTAATATTCAGAGATGA
AGAAGGACTTGTAAATGTAAAAATTCCAGAAGGATACTATTTCTTCATGGGTGATAATACATTGGAAAGTCAAGACAGCC
GCTTTTTTGGATTTGTTCCTGTTGAGAATGTTATTGGAACGACTTTTTTAAGAATTTATCCGTTTGACAGGTTCGGTAAG
ATATAG

Upstream 100 bases:

>100_bases
TAGAAGTATTGAAGAAAGGTAAAACCAGAAGGGCTAAACTCTATTACTTGAGGGATGTTAAAGGAAAGATAAGGATCAAA
GAGAGGAAGGACTGAGCCTT

Downstream 100 bases:

>100_bases
ATAAGTATATTAAAAACCGCCAAAAGGCGGTTTTTTAAGTTTAAGAATGGCGGAGACGGTGGGACTCGAACCCACACGGG
GTGTAACCCCATCGGTTTTC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I-2; Leader peptidase I-2 [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MKEATKKKIKDETLDWIYAIIYALIFGTIIRLYVFETMMVPTPSMVPTIQVYDRLFVEKVTYEFAEPNRGSIVVFWTPFV
DIRAQQQLRTFDRFMDFFAPAQFEGHVKYVKRLVGKPGDTLRLVPVEEKFWEDIKNGEIQNTPEWLDFIIDYYESVDYIP
TQIKNKVSKLEINGEILPEFENIYYLRDAIFEDPKFFDYIAYPDQYRYEIATSDLFFMYKDNFTGRLIPAKPTIEWYKEM
RDTLLFTNFYENELSKLDLTSLIFRDEEGLVNVKIPEGYYFFMGDNTLESQDSRFFGFVPVENVIGTTFLRIYPFDRFGK
I

Sequences:

>Translated_321_residues
MKEATKKKIKDETLDWIYAIIYALIFGTIIRLYVFETMMVPTPSMVPTIQVYDRLFVEKVTYEFAEPNRGSIVVFWTPFV
DIRAQQQLRTFDRFMDFFAPAQFEGHVKYVKRLVGKPGDTLRLVPVEEKFWEDIKNGEIQNTPEWLDFIIDYYESVDYIP
TQIKNKVSKLEINGEILPEFENIYYLRDAIFEDPKFFDYIAYPDQYRYEIATSDLFFMYKDNFTGRLIPAKPTIEWYKEM
RDTLLFTNFYENELSKLDLTSLIFRDEEGLVNVKIPEGYYFFMGDNTLESQDSRFFGFVPVENVIGTTFLRIYPFDRFGK
I
>Mature_321_residues
MKEATKKKIKDETLDWIYAIIYALIFGTIIRLYVFETMMVPTPSMVPTIQVYDRLFVEKVTYEFAEPNRGSIVVFWTPFV
DIRAQQQLRTFDRFMDFFAPAQFEGHVKYVKRLVGKPGDTLRLVPVEEKFWEDIKNGEIQNTPEWLDFIIDYYESVDYIP
TQIKNKVSKLEINGEILPEFENIYYLRDAIFEDPKFFDYIAYPDQYRYEIATSDLFFMYKDNFTGRLIPAKPTIEWYKEM
RDTLLFTNFYENELSKLDLTSLIFRDEEGLVNVKIPEGYYFFMGDNTLESQDSRFFGFVPVENVIGTTFLRIYPFDRFGK
I

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 38302; Mature: 38302

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEATKKKIKDETLDWIYAIIYALIFGTIIRLYVFETMMVPTPSMVPTIQVYDRLFVEKV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
TYEFAEPNRGSIVVFWTPFVDIRAQQQLRTFDRFMDFFAPAQFEGHVKYVKRLVGKPGDT
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCE
LRLVPVEEKFWEDIKNGEIQNTPEWLDFIIDYYESVDYIPTQIKNKVSKLEINGEILPEF
EEEEECHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHEEEECCCCCCCH
ENIYYLRDAIFEDPKFFDYIAYPDQYRYEIATSDLFFMYKDNFTGRLIPAKPTIEWYKEM
HHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCEEEEEEECCCCCEEECCCCCHHHHHHH
RDTLLFTNFYENELSKLDLTSLIFRDEEGLVNVKIPEGYYFFMGDNTLESQDSRFFGFVP
HHHHHHHHHHHHHHHHCCHHHHEEECCCCEEEEEECCCEEEEECCCCCCCCCCCEEEEEE
VENVIGTTFLRIYPFDRFGKI
HHHHHHHHEEEEECCHHHCCC
>Mature Secondary Structure
MKEATKKKIKDETLDWIYAIIYALIFGTIIRLYVFETMMVPTPSMVPTIQVYDRLFVEKV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
TYEFAEPNRGSIVVFWTPFVDIRAQQQLRTFDRFMDFFAPAQFEGHVKYVKRLVGKPGDT
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCE
LRLVPVEEKFWEDIKNGEIQNTPEWLDFIIDYYESVDYIPTQIKNKVSKLEINGEILPEF
EEEEECHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHEEEECCCCCCCH
ENIYYLRDAIFEDPKFFDYIAYPDQYRYEIATSDLFFMYKDNFTGRLIPAKPTIEWYKEM
HHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCEEEEEEECCCCCEEECCCCCHHHHHHH
RDTLLFTNFYENELSKLDLTSLIFRDEEGLVNVKIPEGYYFFMGDNTLESQDSRFFGFVP
HHHHHHHHHHHHHHHHCCHHHHEEECCCCEEEEEECCCEEEEECCCCCCCCCCCEEEEEE
VENVIGTTFLRIYPFDRFGKI
HHHHHHHHEEEEECCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]