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The map label for this gene is soxB [H]

Identifier: 160901758

GI number: 160901758

Start: 289835

End: 290980

Strand: Direct

Name: soxB [H]

Synonym: Pmob_0274

Alternate gene names: 160901758

Gene position: 289835-290980 (Clockwise)

Preceding gene: 160901757

Following gene: 160901759

Centisome position: 13.36

GC content: 37.52

Gene sequence:

>1146_bases
ATGAAAAATAAAGCAAACGTTGTGATAATAGGAGGAGGCGTCGTAGGTTGTTCCATCGCTTATAACCTTGCCAAAAAAGG
GCTTAAAGATGTAGTGTTGCTTGAAAAATCCTACCTTTCAAGCGGAGCAACTGGTAGATGTGGTGCGGGAGTTAGGCAAC
AATGGGGCACCAAACAAAACTGTCTTTTGGCAAGCGAAAGTATGCATATTTTTGAACACTTTGAAGATGTCCTTCAAATA
AAAAGATACATAGAATTAAAGCAAAAAGGTTATTTGTTACTAGCATACTCTGACAAAGAATTAGAGCAATTTAAAAAAAA
TATCGAAGTTCAACACAGTTTAAATATACCTTCTATTCTATTAACTCCTAAAGAAGCTAAAGAGATTGTTCCCGACTTAA
ACATAGAAAAGTTGGTAGGAGCCGCTTACTGTGCTAAAGATGGGCATGCCAACCCTTTCCAAGTGACTTTGGGTTACGCA
GAAGCTGCGCAAAGATTAGGTGTGGAAATAAACAAATTTACCGAAGTCAAAGATATAAAAATTAAGAATGACACAGTGCT
GGGGGTACAAACAAACAAAGGTTTCATAGAATGTAAGAATGTAGTTGTAGCAGCAGGAGGTTGGACACAAAATATAGCTA
AAATGGCTGGAATAGAACTCCCAGTTTACTCCGAAAGACACGAAATATTGGTAACAGAATCTGTTAAAAATATACTCGAT
CCAATGTTAATGTCCTTCTCTTACAATATTTATTGTCAACAAGAACCCAATGGCAGCTTTATCATGGGTTATGGGCCGGA
GAACGAACCACCTAGTTACAATATGGAAAGTTCATGGGAATTCCTTGAAACTATGTCAAAAAAGGCAACGTGGTTATTGC
CTCCTCTTAAAAATATCCGCATCATTAGGCAATGGGCGGGTTTATACAACATTTCGCCAGATAGACAACCAATAGTATCT
CAAATCAATGAGGTAGAAGGTCTATATGTTGCTTGTGGGTTCAGTGGGCATGGTTTTATGCTTGCACCAGCTGTTGGAAT
TCTAATGGCAGATATAGTTACAGGTGATAAATTAACATACGATGTCATTTTAGATTTAGAAAGATTCAACAGAGGAGAAA
TCATTGAAGAGCCCTCTGTTGTATAA

Upstream 100 bases:

>100_bases
ATCAGACCTCCTTACGGAGGAATAACCTTTGAAGAAGTAATAAAAGGAACCATAACGGAAAATGATAAATAAACCTTAAT
ATAACTAGCAGGTGAAAAAT

Downstream 100 bases:

>100_bases
AACTTAAAAAGGAGGAATCAATTTTGAACAACTCAATACCTATTTACGAAATGCCTGAAAATGAGCCAATTTTAAACTAT
GAGCCTGGAAGTAAAGAAAA

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKNKANVVIIGGGVVGCSIAYNLAKKGLKDVVLLEKSYLSSGATGRCGAGVRQQWGTKQNCLLASESMHIFEHFEDVLQI
KRYIELKQKGYLLLAYSDKELEQFKKNIEVQHSLNIPSILLTPKEAKEIVPDLNIEKLVGAAYCAKDGHANPFQVTLGYA
EAAQRLGVEINKFTEVKDIKIKNDTVLGVQTNKGFIECKNVVVAAGGWTQNIAKMAGIELPVYSERHEILVTESVKNILD
PMLMSFSYNIYCQQEPNGSFIMGYGPENEPPSYNMESSWEFLETMSKKATWLLPPLKNIRIIRQWAGLYNISPDRQPIVS
QINEVEGLYVACGFSGHGFMLAPAVGILMADIVTGDKLTYDVILDLERFNRGEIIEEPSVV

Sequences:

>Translated_381_residues
MKNKANVVIIGGGVVGCSIAYNLAKKGLKDVVLLEKSYLSSGATGRCGAGVRQQWGTKQNCLLASESMHIFEHFEDVLQI
KRYIELKQKGYLLLAYSDKELEQFKKNIEVQHSLNIPSILLTPKEAKEIVPDLNIEKLVGAAYCAKDGHANPFQVTLGYA
EAAQRLGVEINKFTEVKDIKIKNDTVLGVQTNKGFIECKNVVVAAGGWTQNIAKMAGIELPVYSERHEILVTESVKNILD
PMLMSFSYNIYCQQEPNGSFIMGYGPENEPPSYNMESSWEFLETMSKKATWLLPPLKNIRIIRQWAGLYNISPDRQPIVS
QINEVEGLYVACGFSGHGFMLAPAVGILMADIVTGDKLTYDVILDLERFNRGEIIEEPSVV
>Mature_381_residues
MKNKANVVIIGGGVVGCSIAYNLAKKGLKDVVLLEKSYLSSGATGRCGAGVRQQWGTKQNCLLASESMHIFEHFEDVLQI
KRYIELKQKGYLLLAYSDKELEQFKKNIEVQHSLNIPSILLTPKEAKEIVPDLNIEKLVGAAYCAKDGHANPFQVTLGYA
EAAQRLGVEINKFTEVKDIKIKNDTVLGVQTNKGFIECKNVVVAAGGWTQNIAKMAGIELPVYSERHEILVTESVKNILD
PMLMSFSYNIYCQQEPNGSFIMGYGPENEPPSYNMESSWEFLETMSKKATWLLPPLKNIRIIRQWAGLYNISPDRQPIVS
QINEVEGLYVACGFSGHGFMLAPAVGILMADIVTGDKLTYDVILDLERFNRGEIIEEPSVV

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=392, Percent_Identity=29.5918367346939, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI197927446, Length=388, Percent_Identity=26.8041237113402, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI21361378, Length=388, Percent_Identity=26.8041237113402, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI194306651, Length=385, Percent_Identity=27.012987012987, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI8923708, Length=411, Percent_Identity=26.2773722627737, Blast_Score=110, Evalue=3e-24,
Organism=Escherichia coli, GI1787559, Length=385, Percent_Identity=24.4155844155844, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787438, Length=429, Percent_Identity=22.1445221445221, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71994052, Length=398, Percent_Identity=23.6180904522613, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI32563613, Length=411, Percent_Identity=26.5206812652068, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71994045, Length=389, Percent_Identity=22.6221079691517, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17541536, Length=432, Percent_Identity=23.1481481481481, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI20130091, Length=386, Percent_Identity=26.1658031088083, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI28571104, Length=391, Percent_Identity=24.5524296675192, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI20129729, Length=418, Percent_Identity=25.5980861244019, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17985989, Length=403, Percent_Identity=23.3250620347395, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 42357; Mature: 42357

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKANVVIIGGGVVGCSIAYNLAKKGLKDVVLLEKSYLSSGATGRCGAGVRQQWGTKQN
CCCCCCEEEEECCHHHHHHHHHHHHCCHHHEEHHHHHHHCCCCCCCCCCCHHHHCCCCCC
CLLASESMHIFEHFEDVLQIKRYIELKQKGYLLLAYSDKELEQFKKNIEVQHSLNIPSIL
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCEEEECCCCEEE
LTPKEAKEIVPDLNIEKLVGAAYCAKDGHANPFQVTLGYAEAAQRLGVEINKFTEVKDIK
ECCHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHCCEEECCCCEEEEE
IKNDTVLGVQTNKGFIECKNVVVAAGGWTQNIAKMAGIELPVYSERHEILVTESVKNILD
EECCEEEEEECCCCEEEEEEEEEECCCCHHHHHHHHCCCCCEECCCCCEEEHHHHHHHHH
PMLMSFSYNIYCQQEPNGSFIMGYGPENEPPSYNMESSWEFLETMSKKATWLLPPLKNIR
HHHHHEEEEEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCEEECCCHHHHH
IIRQWAGLYNISPDRQPIVSQINEVEGLYVACGFSGHGFMLAPAVGILMADIVTGDKLTY
HHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCEEHHHHHHHHHHHHHCCCCEEE
DVILDLERFNRGEIIEEPSVV
EEEEEHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKNKANVVIIGGGVVGCSIAYNLAKKGLKDVVLLEKSYLSSGATGRCGAGVRQQWGTKQN
CCCCCCEEEEECCHHHHHHHHHHHHCCHHHEEHHHHHHHCCCCCCCCCCCHHHHCCCCCC
CLLASESMHIFEHFEDVLQIKRYIELKQKGYLLLAYSDKELEQFKKNIEVQHSLNIPSIL
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCEEEECCCCEEE
LTPKEAKEIVPDLNIEKLVGAAYCAKDGHANPFQVTLGYAEAAQRLGVEINKFTEVKDIK
ECCHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHCCEEECCCCEEEEE
IKNDTVLGVQTNKGFIECKNVVVAAGGWTQNIAKMAGIELPVYSERHEILVTESVKNILD
EECCEEEEEECCCCEEEEEEEEEECCCCHHHHHHHHCCCCCEECCCCCEEEHHHHHHHHH
PMLMSFSYNIYCQQEPNGSFIMGYGPENEPPSYNMESSWEFLETMSKKATWLLPPLKNIR
HHHHHEEEEEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCEEECCCHHHHH
IIRQWAGLYNISPDRQPIVSQINEVEGLYVACGFSGHGFMLAPAVGILMADIVTGDKLTY
HHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCEEHHHHHHHHHHHHHCCCCEEE
DVILDLERFNRGEIIEEPSVV
EEEEEHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]