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The map label for this gene is hutI [H]

Identifier: 160901728

GI number: 160901728

Start: 256961

End: 258247

Strand: Direct

Name: hutI [H]

Synonym: Pmob_0242

Alternate gene names: 160901728

Gene position: 256961-258247 (Clockwise)

Preceding gene: 160901727

Following gene: 160901729

Centisome position: 11.84

GC content: 36.52

Gene sequence:

>1287_bases
ATGGCGATTGATATGAGCGAAAAAGCTACTTTAATAATAAAAAACATCTCAAATTTAATAACGATGAGAGGTCCTAATAG
ACCAAGAAAGAAAGAGGAAATGTCAGAAATTGGCTTAATAAAAAATGGCATAATTGCTGCTTCAAAAGATAAGATTATCT
ACGTTGGAAGTGGTGATTTGCCAAAAGACATAGAAATAGCTCAAGATGCAAAAATTATAAACGCCCAAGGGAAAACTGTA
ACACCCGGTTTAATAGACTCTCACACTCATTTGGTCCATGGTGGCTCAAGGGAATATGAATTATTTAAAAAATTAGAAGG
TGAGAGTTACTTAGATATTTTAAGTTCTGGGGGAGGAATATACGACACCGTTGAATCAACTAAAAAGGCATCTTTTGATG
AATTACTTAAAAAGGCAGAAAAGAGTTTAAATAGAATGTTGTCTTACGGAGTAACAACCGTTGAAGCAAAAAGCGGTTAT
GGGCTTGATGACTTTGACACAGAATTGAAACAGCTTGAGGTCATAAAGGAACTCAATAGAATCCACCCCATAGATTTGGT
TCCTACATTTTTGGGGGCCCATGCAATACCTAAAAAGTACCAAGGCAACGTCGATAAATTCGTAGATATACTCATAACTG
AAATGATCCCGTATGTGGCAGAAAAAAATTTAGCTAAATTTTGTGATGTATTCTGTGAAAAAGGAGTTTTCTCAGTTGAT
CAATCCAGAAAAATACTTTCTGCTGCAAAAGAACACGGTCTATTCCTCAAAATTCACGCAGACGAAATAGAACCTTTAGG
AGGTACCGAATTAGCTGCTGAGTTAGGCTGCGTTTCAGCAGATCATTTGGTAGGTGCAAGCGATGAAGGCTTGAAAAAAA
TGGCTGAGAACAACGTTATAGCTACCCTTCTTCCTACAACAACCTTCTTTTTGCAAAGTGAGAAGTATGCAAACGCTAGA
AAGATGATTGAACTTGGTATACCAATTGCATTGTCGACCGATTATAACCCAGGAAGTTCGCCTACAGAAAATTTACAATT
GGTTATGACGTTTGGGGCAATAAAATTACATATGAATCCAAAGGAAATAATTACATCGGTTACTATTAACGCAGCCTGTG
CGTTGAAATTAGAAGATAAAATTGGTAGTTTGGAGGTAGGTAAAAAAGCTGATATGGCGATTTTCGATGTTCCAAATATA
GAATACTTAATATACCACTTCGGAGTAAACCACACTCAAACTGTTATCAAAAATGGAGAGGTTCATGATATAGCCGTGGT
CTCTTGA

Upstream 100 bases:

>100_bases
ATAGTTGGGTTGGTACCTTTGAATGCCCTTGTTGATACAGCTGATTACTTTTTAAAATTAGAAGATTTCAGTTATGACAA
AGTTTTGGAGAATAGGATTT

Downstream 100 bases:

>100_bases
CAAAGCCTATAACGTAGTGTATAATAATTTTGATATATTAACATAAATAACTTTTTCGCCGGGGTGGTGGAATTGGTAGA
CACGTATGGTTGAGGGCCAT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MAIDMSEKATLIIKNISNLITMRGPNRPRKKEEMSEIGLIKNGIIAASKDKIIYVGSGDLPKDIEIAQDAKIINAQGKTV
TPGLIDSHTHLVHGGSREYELFKKLEGESYLDILSSGGGIYDTVESTKKASFDELLKKAEKSLNRMLSYGVTTVEAKSGY
GLDDFDTELKQLEVIKELNRIHPIDLVPTFLGAHAIPKKYQGNVDKFVDILITEMIPYVAEKNLAKFCDVFCEKGVFSVD
QSRKILSAAKEHGLFLKIHADEIEPLGGTELAAELGCVSADHLVGASDEGLKKMAENNVIATLLPTTTFFLQSEKYANAR
KMIELGIPIALSTDYNPGSSPTENLQLVMTFGAIKLHMNPKEIITSVTINAACALKLEDKIGSLEVGKKADMAIFDVPNI
EYLIYHFGVNHTQTVIKNGEVHDIAVVS

Sequences:

>Translated_428_residues
MAIDMSEKATLIIKNISNLITMRGPNRPRKKEEMSEIGLIKNGIIAASKDKIIYVGSGDLPKDIEIAQDAKIINAQGKTV
TPGLIDSHTHLVHGGSREYELFKKLEGESYLDILSSGGGIYDTVESTKKASFDELLKKAEKSLNRMLSYGVTTVEAKSGY
GLDDFDTELKQLEVIKELNRIHPIDLVPTFLGAHAIPKKYQGNVDKFVDILITEMIPYVAEKNLAKFCDVFCEKGVFSVD
QSRKILSAAKEHGLFLKIHADEIEPLGGTELAAELGCVSADHLVGASDEGLKKMAENNVIATLLPTTTFFLQSEKYANAR
KMIELGIPIALSTDYNPGSSPTENLQLVMTFGAIKLHMNPKEIITSVTINAACALKLEDKIGSLEVGKKADMAIFDVPNI
EYLIYHFGVNHTQTVIKNGEVHDIAVVS
>Mature_427_residues
AIDMSEKATLIIKNISNLITMRGPNRPRKKEEMSEIGLIKNGIIAASKDKIIYVGSGDLPKDIEIAQDAKIINAQGKTVT
PGLIDSHTHLVHGGSREYELFKKLEGESYLDILSSGGGIYDTVESTKKASFDELLKKAEKSLNRMLSYGVTTVEAKSGYG
LDDFDTELKQLEVIKELNRIHPIDLVPTFLGAHAIPKKYQGNVDKFVDILITEMIPYVAEKNLAKFCDVFCEKGVFSVDQ
SRKILSAAKEHGLFLKIHADEIEPLGGTELAAELGCVSADHLVGASDEGLKKMAENNVIATLLPTTTFFLQSEKYANARK
MIELGIPIALSTDYNPGSSPTENLQLVMTFGAIKLHMNPKEIITSVTINAACALKLEDKIGSLEVGKKADMAIFDVPNIE
YLIYHFGVNHTQTVIKNGEVHDIAVVS

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=428, Percent_Identity=36.6822429906542, Blast_Score=244, Evalue=8e-65,
Organism=Caenorhabditis elegans, GI17555004, Length=380, Percent_Identity=35.2631578947368, Blast_Score=223, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 46864; Mature: 46732

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIDMSEKATLIIKNISNLITMRGPNRPRKKEEMSEIGLIKNGIIAASKDKIIYVGSGDL
CCCCCCCCCEEEEEEHHHHEEECCCCCCCHHHHHHHHCCHHCCEEEECCCCEEEEECCCC
PKDIEIAQDAKIINAQGKTVTPGLIDSHTHLVHGGSREYELFKKLEGESYLDILSSGGGI
CCCCCHHCCCEEEECCCCEECCCCCCCCCEEEECCCHHHHHHHHHCCCHHHHHHHCCCCE
YDTVESTKKASFDELLKKAEKSLNRMLSYGVTTVEAKSGYGLDDFDTELKQLEVIKELNR
EHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
IHPIDLVPTFLGAHAIPKKYQGNVDKFVDILITEMIPYVAEKNLAKFCDVFCEKGVFSVD
CCCHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QSRKILSAAKEHGLFLKIHADEIEPLGGTELAAELGCVSADHLVGASDEGLKKMAENNVI
HHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHCCCCHHHCCCCCCHHHHHHHHCCEE
ATLLPTTTFFLQSEKYANARKMIELGIPIALSTDYNPGSSPTENLQLVMTFGAIKLHMNP
EEEECCEEEEEECCHHHCHHHHHEECCCEEEECCCCCCCCCCCCEEEEEEEEEEEEECCH
KEIITSVTINAACALKLEDKIGSLEVGKKADMAIFDVPNIEYLIYHFGVNHTQTVIKNGE
HHHHHHEEECEEEEEEECCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCHHHHHCCCC
VHDIAVVS
CCEEEEEC
>Mature Secondary Structure 
AIDMSEKATLIIKNISNLITMRGPNRPRKKEEMSEIGLIKNGIIAASKDKIIYVGSGDL
CCCCCCCCEEEEEEHHHHEEECCCCCCCHHHHHHHHCCHHCCEEEECCCCEEEEECCCC
PKDIEIAQDAKIINAQGKTVTPGLIDSHTHLVHGGSREYELFKKLEGESYLDILSSGGGI
CCCCCHHCCCEEEECCCCEECCCCCCCCCEEEECCCHHHHHHHHHCCCHHHHHHHCCCCE
YDTVESTKKASFDELLKKAEKSLNRMLSYGVTTVEAKSGYGLDDFDTELKQLEVIKELNR
EHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
IHPIDLVPTFLGAHAIPKKYQGNVDKFVDILITEMIPYVAEKNLAKFCDVFCEKGVFSVD
CCCHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QSRKILSAAKEHGLFLKIHADEIEPLGGTELAAELGCVSADHLVGASDEGLKKMAENNVI
HHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHCCCCHHHCCCCCCHHHHHHHHCCEE
ATLLPTTTFFLQSEKYANARKMIELGIPIALSTDYNPGSSPTENLQLVMTFGAIKLHMNP
EEEECCEEEEEECCHHHCHHHHHEECCCEEEECCCCCCCCCCCCEEEEEEEEEEEEECCH
KEIITSVTINAACALKLEDKIGSLEVGKKADMAIFDVPNIEYLIYHFGVNHTQTVIKNGE
HHHHHHEEECEEEEEEECCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCHHHHHCCCC
VHDIAVVS
CCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA