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The map label for this gene is rnpA

Identifier: 160877624

GI number: 160877624

Start: 5346709

End: 5347065

Strand: Reverse

Name: rnpA

Synonym: Sbal195_4523

Alternate gene names: 160877624

Gene position: 5347065-5346709 (Counterclockwise)

Preceding gene: 160877625

Following gene: 160877623

Centisome position: 100.0

GC content: 42.58

Gene sequence:

>357_bases
TTGACTAGCTATACCTTTTCGCGGGAGTTACGTTTGTTAACTCCCGCGCAATTTAAATCTGTATTTTCCAATCCCATCAA
AGCATCTTCTGCTGAAATTACCTTGCTCGCTATTCCTAACACGGAACAACATCCGCGTATGGGCCTTACTGTTGCCAAAC
GCTTTGTAAAACGCGCCAATCAACGTAACCGTATTAAGCGTGTGATCAGAGATAGTTTTCGCTTAAATCAACACGACATT
CCTCATCTTGATATTGTTGTGCTTGTCAGAAATGGCGTGATGGAAATGGAAAACGCTGAAATCAACAAATTGATAGAAAA
GCTATGGCGCAAACTCAGTCGCCGCTACAATGGCTAG

Upstream 100 bases:

>100_bases
CTTCCGCGCTCGTATGGCTACTGTAGGCGGCCGCAAGGTGCTTGCACGTCGTCGTGCGAAAGGTCGCGCTCGTTTATCTG
CTTAATAAGTGGGTAACTAG

Downstream 100 bases:

>100_bases
CGACCACGTTAATTCGTGGCTATCAAGTATTCATAAGCCCTATACTGGGCCCTCGATGCCGTTTCAATCCCACCTGCTCT
CACTACGCTATTGAAGCAAT

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 118; Mature: 117

Protein sequence:

>118_residues
MTSYTFSRELRLLTPAQFKSVFSNPIKASSAEITLLAIPNTEQHPRMGLTVAKRFVKRANQRNRIKRVIRDSFRLNQHDI
PHLDIVVLVRNGVMEMENAEINKLIEKLWRKLSRRYNG

Sequences:

>Translated_118_residues
MTSYTFSRELRLLTPAQFKSVFSNPIKASSAEITLLAIPNTEQHPRMGLTVAKRFVKRANQRNRIKRVIRDSFRLNQHDI
PHLDIVVLVRNGVMEMENAEINKLIEKLWRKLSRRYNG
>Mature_117_residues
TSYTFSRELRLLTPAQFKSVFSNPIKASSAEITLLAIPNTEQHPRMGLTVAKRFVKRANQRNRIKRVIRDSFRLNQHDIP
HLDIVVLVRNGVMEMENAEINKLIEKLWRKLSRRYNG

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

Organism=Escherichia coli, GI1790139, Length=118, Percent_Identity=50, Blast_Score=127, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_SHEB2 (B8EDW7)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002360216.1
- ProteinModelPortal:   B8EDW7
- SMR:   B8EDW7
- GeneID:   7089132
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_4327
- HOGENOM:   HBG728160
- OMA:   LVIGKKS
- ProtClustDB:   PRK01732
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 13830; Mature: 13699

Theoretical pI: Translated: 11.71; Mature: 11.71

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYTFSRELRLLTPAQFKSVFSNPIKASSAEITLLAIPNTEQHPRMGLTVAKRFVKRAN
CCCCCCCCCCEECCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCC
QRNRIKRVIRDSFRLNQHDIPHLDIVVLVRNGVMEMENAEINKLIEKLWRKLSRRYNG
HHHHHHHHHHHHHCCCCCCCCCHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSYTFSRELRLLTPAQFKSVFSNPIKASSAEITLLAIPNTEQHPRMGLTVAKRFVKRAN
CCCCCCCCCEECCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCC
QRNRIKRVIRDSFRLNQHDIPHLDIVVLVRNGVMEMENAEINKLIEKLWRKLSRRYNG
HHHHHHHHHHHHHCCCCCCCCCHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA