Click here to switch to the map view.

The map label for this gene is atpA2 [H]

Identifier: 160877610

GI number: 160877610

Start: 5333501

End: 5335042

Strand: Reverse

Name: atpA2 [H]

Synonym: Sbal195_4509

Alternate gene names: 160877610

Gene position: 5335042-5333501 (Counterclockwise)

Preceding gene: 160877611

Following gene: 160877609

Centisome position: 99.77

GC content: 46.95

Gene sequence:

>1542_bases
ATGCAACTGAATTCCACTGAAATCAGCGATCTGATTAAGCAGCGGATCGAGCAGTTCGAAGTCGTTAGCGAATCTCGTAA
CGAAGGTACTATCGTTGCGGTAAGTGACGGCATCATCCGCATCCACGGCCTAGCCGACGTGATGCAAGGTGAGATGATCG
AACTGCCTGGTAACCGTTTTGCAATCGCGTTGAACCTTGAACGTGATTCTGTCGGTGCCGTAGTAATGGGTCCTTATGCT
GATTTAGCAGAAGGCGTAAAAGTGAAAACGACTGGCCGTATTCTGGAAGTTCCAGTTGGCCGCGGTCTTCTTGGCCGCGT
TGTTAACACTCTAGGTGAGCCAATTGACGGAAAAGGACCTATCGATAACGATGGTTACTCGCCAATTGAAGTTATCGCAC
CAGGTGTTATTGAACGTCAGTCTGTTGATCAACCAGTTCAAACTGGTTACAAAGCCGTTGATGCCATGATCCCTATCGGT
CGTGGTCAACGTGAATTGATCATTGGCGACCGTCAAACTGGTAAAACAGCTATGGCGATCGACGCAATTATCAACCAGAA
AAATTCTGGCATTAAATGTGTGTACGTTGCGATTGGCCAAAAGGCTTCTACTATCGCTAACGTAGTGCGCAAGCTAGAAG
AACACGGTGCGTTAGCTAACACTATCGTTGTTGTTGCAACGGCTTCTGAAGCTGCTGCTCTGCAATACTTAGCGCCATAT
TCTGGTTGTTCTATGGGTGAATACTTCCGTGACCGCGGTGAAGATTCTTTGATCGTATACGATGATTTGTCTAAGCAAGC
AGTTGCTTATCGTCAAATTTCGTTACTGCTCAAGCGTCCACCAGGCCGTGAAGCTTACCCAGGTGACGTATTCTATCTAC
ACTCACGTTTACTAGAGCGTGCATCACGCGTTAACGCGATTTATGTAGAGAAGTTCACTAAAGGTGCAGTAACTGGCAAA
ACCGGTTCTTTAACCGCGCTGCCTATTATTGAAACGCAAGCGGGTGACGTTTCTGCATTCGTACCGACCAACGTAATTTC
TATTACCGATGGTCAGATCTTCCTTGAGACCGATCTGTTTAACTCTGGCCTACGTCCAGCGGTTAACCCAGGTATTTCTG
TTTCTCGTGTTGGTGGTGCGGCTCAGACTAAGATCATCAAGAAACTGTCTGGTGGTATTCGTACCGCACTAGCACAGTAT
CGTGAGCTTGCTGCGTTCTCGCAATTTGCATCTGATCTTGACGATGCAACACGTGCTCAACTTGAGCATGGTGTGCGTGT
TACCGAACTGATGAAGCAAAAGCAATATGCTCCAATGAGCGTAGCCGCTCAAGCTGTGTCTATTTTCTCAGCTGAAAAAG
GTTACCTGAAGAGTGTTGAGCTGAATAAGGTCGGTAATTTCGAAGCCGCTCTGCTCTCGTTCATGAACAGCGAGCATGCT
CCTTTAATGAAGCTTATCAATGATACTGGCGATTATAGCGCTGATATCGAAGCTGAATTAAAAGCTGGCCTCGACAAGTT
CGTAGCAACCCAAACCTGGTAA

Upstream 100 bases:

>100_bases
GTGTAATCATTAAGACAGGAGACCTAGTCATCGATGGCTCGGTCCGCGGTAAGTTATCGCGTCTGTCTGATAAGCTGCAG
TCGTAATTGGGAGTTTGAGC

Downstream 100 bases:

>100_bases
CAATGATAGAGGTGTCTTAAGACACCTCAGGTCCAGATTGGAGAGTAGAGATGGCCGGCGCTAAAGAGATTAAAACCAAG
ATCGCGAGTGTGAAAAACAC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 2; F-ATPase subunit alpha 2 [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNSTEISDLIKQRIEQFEVVSESRNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRFAIALNLERDSVGAVVMGPYA
DLAEGVKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGPIDNDGYSPIEVIAPGVIERQSVDQPVQTGYKAVDAMIPIG
RGQRELIIGDRQTGKTAMAIDAIINQKNSGIKCVYVAIGQKASTIANVVRKLEEHGALANTIVVVATASEAAALQYLAPY
SGCSMGEYFRDRGEDSLIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERASRVNAIYVEKFTKGAVTGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRTALAQY
RELAAFSQFASDLDDATRAQLEHGVRVTELMKQKQYAPMSVAAQAVSIFSAEKGYLKSVELNKVGNFEAALLSFMNSEHA
PLMKLINDTGDYSADIEAELKAGLDKFVATQTW

Sequences:

>Translated_513_residues
MQLNSTEISDLIKQRIEQFEVVSESRNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRFAIALNLERDSVGAVVMGPYA
DLAEGVKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGPIDNDGYSPIEVIAPGVIERQSVDQPVQTGYKAVDAMIPIG
RGQRELIIGDRQTGKTAMAIDAIINQKNSGIKCVYVAIGQKASTIANVVRKLEEHGALANTIVVVATASEAAALQYLAPY
SGCSMGEYFRDRGEDSLIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERASRVNAIYVEKFTKGAVTGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRTALAQY
RELAAFSQFASDLDDATRAQLEHGVRVTELMKQKQYAPMSVAAQAVSIFSAEKGYLKSVELNKVGNFEAALLSFMNSEHA
PLMKLINDTGDYSADIEAELKAGLDKFVATQTW
>Mature_513_residues
MQLNSTEISDLIKQRIEQFEVVSESRNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRFAIALNLERDSVGAVVMGPYA
DLAEGVKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGPIDNDGYSPIEVIAPGVIERQSVDQPVQTGYKAVDAMIPIG
RGQRELIIGDRQTGKTAMAIDAIINQKNSGIKCVYVAIGQKASTIANVVRKLEEHGALANTIVVVATASEAAALQYLAPY
SGCSMGEYFRDRGEDSLIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERASRVNAIYVEKFTKGAVTGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRTALAQY
RELAAFSQFASDLDDATRAQLEHGVRVTELMKQKQYAPMSVAAQAVSIFSAEKGYLKSVELNKVGNFEAALLSFMNSEHA
PLMKLINDTGDYSADIEAELKAGLDKFVATQTW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=513, Percent_Identity=56.140350877193, Blast_Score=561, Evalue=1e-160,
Organism=Homo sapiens, GI4757810, Length=513, Percent_Identity=56.140350877193, Blast_Score=561, Evalue=1e-160,
Organism=Homo sapiens, GI32189394, Length=362, Percent_Identity=26.7955801104972, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI19913428, Length=323, Percent_Identity=26.625386996904, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI19913426, Length=322, Percent_Identity=26.7080745341615, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI19913424, Length=263, Percent_Identity=27.7566539923954, Blast_Score=81, Evalue=3e-15,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=84.7953216374269, Blast_Score=908, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=340, Percent_Identity=27.0588235294118, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788251, Length=378, Percent_Identity=24.3386243386243, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=515, Percent_Identity=55.5339805825243, Blast_Score=560, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI71988080, Length=515, Percent_Identity=55.5339805825243, Blast_Score=558, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI71988074, Length=515, Percent_Identity=51.8446601941748, Blast_Score=513, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI17510931, Length=368, Percent_Identity=25.8152173913043, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=313, Percent_Identity=27.4760383386581, Blast_Score=108, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=364, Percent_Identity=25.8241758241758, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17565854, Length=254, Percent_Identity=26.7716535433071, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17509265, Length=47, Percent_Identity=65.9574468085106, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=513, Percent_Identity=55.5555555555556, Blast_Score=565, Evalue=1e-162,
Organism=Saccharomyces cerevisiae, GI6322581, Length=474, Percent_Identity=25.9493670886076, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6319603, Length=376, Percent_Identity=27.6595744680851, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24658560, Length=514, Percent_Identity=54.4747081712062, Blast_Score=548, Evalue=1e-156,
Organism=Drosophila melanogaster, GI281361666, Length=354, Percent_Identity=26.8361581920904, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24646341, Length=354, Percent_Identity=26.8361581920904, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI17136796, Length=354, Percent_Identity=26.8361581920904, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24638766, Length=434, Percent_Identity=25.1152073732719, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI28574560, Length=321, Percent_Identity=26.1682242990654, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24583988, Length=255, Percent_Identity=27.4509803921569, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24583986, Length=255, Percent_Identity=27.4509803921569, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24583984, Length=255, Percent_Identity=27.4509803921569, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24583992, Length=255, Percent_Identity=27.4509803921569, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI20129479, Length=373, Percent_Identity=25.7372654155496, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55193; Mature: 55193

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNSTEISDLIKQRIEQFEVVSESRNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRF
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEECHHHHHCCCEEECCCCEE
AIALNLERDSVGAVVMGPYADLAEGVKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGP
EEEEEECCCCCCEEEECCCHHHHCCCEEEECCCEEEECCCCCHHHHHHHHHCCCCCCCCC
IDNDGYSPIEVIAPGVIERQSVDQPVQTGYKAVDAMIPIGRGQRELIIGDRQTGKTAMAI
CCCCCCCCHHHHCCCCCCHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHH
DAIINQKNSGIKCVYVAIGQKASTIANVVRKLEEHGALANTIVVVATASEAAALQYLAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHCCC
SGCSMGEYFRDRGEDSLIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ASRVNAIYVEKFTKGAVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLF
HHHCCEEEEEHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECCC
NSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFSQFASDLDDATRAQ
CCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEHGVRVTELMKQKQYAPMSVAAQAVSIFSAEKGYLKSVELNKVGNFEAALLSFMNSEHA
HHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCC
PLMKLINDTGDYSADIEAELKAGLDKFVATQTW
HHHHHHHCCCCCCCCCHHHHHHCHHHHHHCCCC
>Mature Secondary Structure
MQLNSTEISDLIKQRIEQFEVVSESRNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRF
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEECHHHHHCCCEEECCCCEE
AIALNLERDSVGAVVMGPYADLAEGVKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGP
EEEEEECCCCCCEEEECCCHHHHCCCEEEECCCEEEECCCCCHHHHHHHHHCCCCCCCCC
IDNDGYSPIEVIAPGVIERQSVDQPVQTGYKAVDAMIPIGRGQRELIIGDRQTGKTAMAI
CCCCCCCCHHHHCCCCCCHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHH
DAIINQKNSGIKCVYVAIGQKASTIANVVRKLEEHGALANTIVVVATASEAAALQYLAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHCCC
SGCSMGEYFRDRGEDSLIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ASRVNAIYVEKFTKGAVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLF
HHHCCEEEEEHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECCC
NSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFSQFASDLDDATRAQ
CCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEHGVRVTELMKQKQYAPMSVAAQAVSIFSAEKGYLKSVELNKVGNFEAALLSFMNSEHA
HHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCC
PLMKLINDTGDYSADIEAELKAGLDKFVATQTW
HHHHHHHCCCCCCCCCHHHHHHCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA