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The map label for this gene is ykoW [H]

Identifier: 160877598

GI number: 160877598

Start: 5312008

End: 5314458

Strand: Reverse

Name: ykoW [H]

Synonym: Sbal195_4497

Alternate gene names: 160877598

Gene position: 5314458-5312008 (Counterclockwise)

Preceding gene: 160877599

Following gene: 160877595

Centisome position: 99.39

GC content: 47.41

Gene sequence:

>2451_bases
ATGCTTCGTAAGCTTTCGCTCGCGGTACTGCTCCCTCTGTGTATGCTGACACTATATTTAGTGTTGGTCATAGGCGAGTA
CCTGTTTGAAAGCGATCAAGTGCGTGCTGAATTGGCGCAGCGACAATCGACACTGATAAAGCAGCAGTTGTTCCGGATGC
AGAATGTGGTTCAATCGGCGCAGGCTTTACAGGATGTGGAGCGGATCGAGCAGGAGGTTTCCTTAGCTGCGCTGGATATG
GGCACTATGGTTTATATCTTAGTTGATGCTGATAGCCGTATTCGTTTTGCAAACCATACTGTTTGGCGCGATAGCAATGC
CATGCAAGTCATTGATGGTTATGATGCTACTCGTCATCGTGCTGTGGTTCAGGCTTTCCTGCCACAAATTCTTGTTAATC
TCGAACGCTTAACCATTCAAGCATATTATCCCGTCTTGCCTCAGTATGGTGGTGCGGTTGATTTGATTTATCTTGAAGCC
GATTTAGCGCCTTTAGTCGCCGAAGCTTCCGCTAAGTTACAACAACGTTTTATGCGGGTTTGGGGGCTGGGTGGATTATT
ACTGATTGGTTTTACCTTCATTCTCTATTTCCTATTGATCCGTCCATTCCAAATATTAAGCGAGGCCGCTAAACAGGTAG
GGACTTCTTCCTTTTCGACATCGATCCCATGGAGCTCATCAGAAGTCTTATCATTGCAAGCCAGTTTGCAGCAGGTACAT
GAACGTTTGAGTCGTGCCGTGAAACAGTTGAATGACAGCGAACTGCGCTGGCTGTTTGCGGTGGAAGGCTCGCGGAACGG
TATTTGGGATTGGGATATCAGTACGGGTGAGGTTTTTCTGTCTGATCGCTGGAAAGAGATGATCGGTTATGCGCCGGATG
AATTAGCGGGCGTATTCCAGACTTGGGAAACGCGGTTACATCCCGATGATAGGGATATCGTACTTGATGCGTTGCAGGAG
TACGTTAGCGGTAAGAGTAAAGAATTTGAAAGTGTCCATCGACTGCGGCATAGAGAGGGGCATTATGTGTGGGTGCTGGA
TCGCGGCATGTTGGTTGATTGGGACCCTCAAGGACGTCCGACTCGGATGATCGGCATTCATATGGATGTGTCAGAAAGTG
CCAAAAACCATGCTGCGATTAATGAACTTGTGGATCAATCGGTTACGGGTCGCAAGATGTTACCCGATGTCTTTATGGCG
CGACTGTCGCAATTTTTAACCCAAGGTAATAGTTCAGGTCAATGGGGATCATTGCTGCTTGTTGAGGTGGATAGGTTAGG
CTTGGTCGCAACTTTAAACTCTCACGAATTAGAGCGTTTACTCACGCAAGTGGCTGCACGTCTATCGAGTTATTTCACTG
AGAATATTACCGTTGGCCGATTGGAGTCCGGTGATTTTGTTTTGCTGGCTAAAGACTTAGCGATAGATGCTTCAGTGGCT
GCGCGTCGTGCTTTAGCGCTTGCGAGTGAGTTAAGGCAAGTGATTGCTCGACCATTCCATTACGGTCATCATCACTTTGA
GCTCAGCGCGAATGTGGGGATTTGTTTGCTCGACAGCATAGAGACCTTAGATCCAGCTTTAGTCATGCGCCGCGCCGAGC
TAGCAACCTTGAGTGCTAAGCGACCAGGGCAAGCGGGATGCGCTTTCTATCATGCTGAGATGGATTTACGTCTGAGCCGT
GATGAACAGTTACAACAGGAATTACAGACAGCATTACAGCAAGATAGCATGACGTTAATGTTCCAACCTGTGATGAATGC
GCACAGTGAATTGGTCTCGGCTGAAGTGCTCACGCGTTGGTATCGTGCCGATGGCGAGTTTATCCCACCTGCAGAGTTCG
TGGCGTTAGCTGAACAGGGAGGAATGATTGCAGAACTCGATCTTTGGGTCGCTAAACGTGTGTGTCAGTTTATTCAGACA
TCCCATGCCCAAGGCCGGAGTTTGCCGACTTTAACTCTTAATATCAGTGCATTCTCATTTGGGCAGGCAGATTTTCTTGA
TGCATTGATTGCGTTAACTAAAGAGCATGGCATTGTGGCTCATCAACTGGGTATTGAGCTCAATGAGGCCGCATTTTTAA
TGCAACCACAGTTTGTGGCTGAGCGCGTGTCTAAGTTAGTTGATGCAGGGATAGGCATCGTCCTCGATCATTTCGGTTCT
GGCTCGAGTGCTTTGAGTTGTTTAGCCAACCAGCCATTAGTTGCGGTTAAATTGGATATGAGTTGTATTGATTCATTAGC
CACAATGCCACAAAGAGTGAAGGCGTTAATTGTCTCTGCGCAGCAGTTTAATTTGCACGTGGTGGCTAAAGGCGTTGAAT
CACCCCAACACTATCAAGCCTTTGTTGAATTTGGCTGTGATGGTTATCAGGGCTATTTATTCAGCCGAGCGTTAAACCAA
GTGGACTTTATCCAGCTTGTTTGTCCTCGTCCTTTATTGCGAAGCGTTTAA

Upstream 100 bases:

>100_bases
CAAGATCTCGCTTAGTTTGATAAGTCCTTTTGCTTAGTGGTTAGTTTCCCGTTAGCATACAAAAACTATTCACATTTTTG
TTAAAGGCTGTCTGTTGCCT

Downstream 100 bases:

>100_bases
AGAAGTCGAGGGCATAATTTAAGGCTTGGTTTCGATAGGCGTCTTTTTCCATAAAAATCTCATGGGCAGCCCCTGCTATC
ACCTTCAATTGGCAATGAGT

Product: PAS/PAC and GAF sensor(s)-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 816; Mature: 816

Protein sequence:

>816_residues
MLRKLSLAVLLPLCMLTLYLVLVIGEYLFESDQVRAELAQRQSTLIKQQLFRMQNVVQSAQALQDVERIEQEVSLAALDM
GTMVYILVDADSRIRFANHTVWRDSNAMQVIDGYDATRHRAVVQAFLPQILVNLERLTIQAYYPVLPQYGGAVDLIYLEA
DLAPLVAEASAKLQQRFMRVWGLGGLLLIGFTFILYFLLIRPFQILSEAAKQVGTSSFSTSIPWSSSEVLSLQASLQQVH
ERLSRAVKQLNDSELRWLFAVEGSRNGIWDWDISTGEVFLSDRWKEMIGYAPDELAGVFQTWETRLHPDDRDIVLDALQE
YVSGKSKEFESVHRLRHREGHYVWVLDRGMLVDWDPQGRPTRMIGIHMDVSESAKNHAAINELVDQSVTGRKMLPDVFMA
RLSQFLTQGNSSGQWGSLLLVEVDRLGLVATLNSHELERLLTQVAARLSSYFTENITVGRLESGDFVLLAKDLAIDASVA
ARRALALASELRQVIARPFHYGHHHFELSANVGICLLDSIETLDPALVMRRAELATLSAKRPGQAGCAFYHAEMDLRLSR
DEQLQQELQTALQQDSMTLMFQPVMNAHSELVSAEVLTRWYRADGEFIPPAEFVALAEQGGMIAELDLWVAKRVCQFIQT
SHAQGRSLPTLTLNISAFSFGQADFLDALIALTKEHGIVAHQLGIELNEAAFLMQPQFVAERVSKLVDAGIGIVLDHFGS
GSSALSCLANQPLVAVKLDMSCIDSLATMPQRVKALIVSAQQFNLHVVAKGVESPQHYQAFVEFGCDGYQGYLFSRALNQ
VDFIQLVCPRPLLRSV

Sequences:

>Translated_816_residues
MLRKLSLAVLLPLCMLTLYLVLVIGEYLFESDQVRAELAQRQSTLIKQQLFRMQNVVQSAQALQDVERIEQEVSLAALDM
GTMVYILVDADSRIRFANHTVWRDSNAMQVIDGYDATRHRAVVQAFLPQILVNLERLTIQAYYPVLPQYGGAVDLIYLEA
DLAPLVAEASAKLQQRFMRVWGLGGLLLIGFTFILYFLLIRPFQILSEAAKQVGTSSFSTSIPWSSSEVLSLQASLQQVH
ERLSRAVKQLNDSELRWLFAVEGSRNGIWDWDISTGEVFLSDRWKEMIGYAPDELAGVFQTWETRLHPDDRDIVLDALQE
YVSGKSKEFESVHRLRHREGHYVWVLDRGMLVDWDPQGRPTRMIGIHMDVSESAKNHAAINELVDQSVTGRKMLPDVFMA
RLSQFLTQGNSSGQWGSLLLVEVDRLGLVATLNSHELERLLTQVAARLSSYFTENITVGRLESGDFVLLAKDLAIDASVA
ARRALALASELRQVIARPFHYGHHHFELSANVGICLLDSIETLDPALVMRRAELATLSAKRPGQAGCAFYHAEMDLRLSR
DEQLQQELQTALQQDSMTLMFQPVMNAHSELVSAEVLTRWYRADGEFIPPAEFVALAEQGGMIAELDLWVAKRVCQFIQT
SHAQGRSLPTLTLNISAFSFGQADFLDALIALTKEHGIVAHQLGIELNEAAFLMQPQFVAERVSKLVDAGIGIVLDHFGS
GSSALSCLANQPLVAVKLDMSCIDSLATMPQRVKALIVSAQQFNLHVVAKGVESPQHYQAFVEFGCDGYQGYLFSRALNQ
VDFIQLVCPRPLLRSV
>Mature_816_residues
MLRKLSLAVLLPLCMLTLYLVLVIGEYLFESDQVRAELAQRQSTLIKQQLFRMQNVVQSAQALQDVERIEQEVSLAALDM
GTMVYILVDADSRIRFANHTVWRDSNAMQVIDGYDATRHRAVVQAFLPQILVNLERLTIQAYYPVLPQYGGAVDLIYLEA
DLAPLVAEASAKLQQRFMRVWGLGGLLLIGFTFILYFLLIRPFQILSEAAKQVGTSSFSTSIPWSSSEVLSLQASLQQVH
ERLSRAVKQLNDSELRWLFAVEGSRNGIWDWDISTGEVFLSDRWKEMIGYAPDELAGVFQTWETRLHPDDRDIVLDALQE
YVSGKSKEFESVHRLRHREGHYVWVLDRGMLVDWDPQGRPTRMIGIHMDVSESAKNHAAINELVDQSVTGRKMLPDVFMA
RLSQFLTQGNSSGQWGSLLLVEVDRLGLVATLNSHELERLLTQVAARLSSYFTENITVGRLESGDFVLLAKDLAIDASVA
ARRALALASELRQVIARPFHYGHHHFELSANVGICLLDSIETLDPALVMRRAELATLSAKRPGQAGCAFYHAEMDLRLSR
DEQLQQELQTALQQDSMTLMFQPVMNAHSELVSAEVLTRWYRADGEFIPPAEFVALAEQGGMIAELDLWVAKRVCQFIQT
SHAQGRSLPTLTLNISAFSFGQADFLDALIALTKEHGIVAHQLGIELNEAAFLMQPQFVAERVSKLVDAGIGIVLDHFGS
GSSALSCLANQPLVAVKLDMSCIDSLATMPQRVKALIVSAQQFNLHVVAKGVESPQHYQAFVEFGCDGYQGYLFSRALNQ
VDFIQLVCPRPLLRSV

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI87081921, Length=385, Percent_Identity=28.5714285714286, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1787541, Length=369, Percent_Identity=27.9132791327913, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI87081743, Length=252, Percent_Identity=27.7777777777778, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI226510982, Length=404, Percent_Identity=22.7722772277228, Blast_Score=100, Evalue=7e-22,
Organism=Escherichia coli, GI1790496, Length=252, Percent_Identity=28.1746031746032, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87081845, Length=270, Percent_Identity=25.1851851851852, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1787055, Length=258, Percent_Identity=24.031007751938, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI1788849, Length=251, Percent_Identity=27.4900398406374, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788502, Length=253, Percent_Identity=29.2490118577075, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87081980, Length=246, Percent_Identity=26.4227642276423, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI87082096, Length=289, Percent_Identity=25.6055363321799, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786507, Length=249, Percent_Identity=26.1044176706827, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 91269; Mature: 91269

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50112 PAS ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRKLSLAVLLPLCMLTLYLVLVIGEYLFESDQVRAELAQRQSTLIKQQLFRMQNVVQSA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALQDVERIEQEVSLAALDMGTMVYILVDADSRIRFANHTVWRDSNAMQVIDGYDATRHR
HHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEECCCEEEECCCCEEEECCCCHHHHH
AVVQAFLPQILVNLERLTIQAYYPVLPQYGGAVDLIYLEADLAPLVAEASAKLQQRFMRV
HHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHH
WGLGGLLLIGFTFILYFLLIRPFQILSEAAKQVGTSSFSTSIPWSSSEVLSLQASLQQVH
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
ERLSRAVKQLNDSELRWLFAVEGSRNGIWDWDISTGEVFLSDRWKEMIGYAPDELAGVFQ
HHHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCCEEHHHHHHHHHHCCCCHHHHHHHH
TWETRLHPDDRDIVLDALQEYVSGKSKEFESVHRLRHREGHYVWVLDRGMLVDWDPQGRP
HHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCCC
TRMIGIHMDVSESAKNHAAINELVDQSVTGRKMLPDVFMARLSQFLTQGNSSGQWGSLLL
EEEEEEEECHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
VEVDRLGLVATLNSHELERLLTQVAARLSSYFTENITVGRLESGDFVLLAKDLAIDASVA
EEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECHHCCHHHH
ARRALALASELRQVIARPFHYGHHHFELSANVGICLLDSIETLDPALVMRRAELATLSAK
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCHHHCCHHHHHHHHHHHHHCCC
RPGQAGCAFYHAEMDLRLSRDEQLQQELQTALQQDSMTLMFQPVMNAHSELVSAEVLTRW
CCCCCCEEEEEECCCEEECCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHH
YRADGEFIPPAEFVALAEQGGMIAELDLWVAKRVCQFIQTSHAQGRSLPTLTLNISAFSF
HHCCCCCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECC
GQADFLDALIALTKEHGIVAHQLGIELNEAAFLMQPQFVAERVSKLVDAGIGIVLDHFGS
CCHHHHHHHHHHHHCCCEEEHHHCCEECCHHHEECHHHHHHHHHHHHHCCCCEEEECCCC
GSSALSCLANQPLVAVKLDMSCIDSLATMPQRVKALIVSAQQFNLHVVAKGVESPQHYQA
CHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHH
FVEFGCDGYQGYLFSRALNQVDFIQLVCPRPLLRSV
HHHHCCCCHHHHHHHHHHCHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MLRKLSLAVLLPLCMLTLYLVLVIGEYLFESDQVRAELAQRQSTLIKQQLFRMQNVVQSA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALQDVERIEQEVSLAALDMGTMVYILVDADSRIRFANHTVWRDSNAMQVIDGYDATRHR
HHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEECCCEEEECCCCEEEECCCCHHHHH
AVVQAFLPQILVNLERLTIQAYYPVLPQYGGAVDLIYLEADLAPLVAEASAKLQQRFMRV
HHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHH
WGLGGLLLIGFTFILYFLLIRPFQILSEAAKQVGTSSFSTSIPWSSSEVLSLQASLQQVH
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
ERLSRAVKQLNDSELRWLFAVEGSRNGIWDWDISTGEVFLSDRWKEMIGYAPDELAGVFQ
HHHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCCEEHHHHHHHHHHCCCCHHHHHHHH
TWETRLHPDDRDIVLDALQEYVSGKSKEFESVHRLRHREGHYVWVLDRGMLVDWDPQGRP
HHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCCC
TRMIGIHMDVSESAKNHAAINELVDQSVTGRKMLPDVFMARLSQFLTQGNSSGQWGSLLL
EEEEEEEECHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
VEVDRLGLVATLNSHELERLLTQVAARLSSYFTENITVGRLESGDFVLLAKDLAIDASVA
EEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECHHCCHHHH
ARRALALASELRQVIARPFHYGHHHFELSANVGICLLDSIETLDPALVMRRAELATLSAK
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCHHHCCHHHHHHHHHHHHHCCC
RPGQAGCAFYHAEMDLRLSRDEQLQQELQTALQQDSMTLMFQPVMNAHSELVSAEVLTRW
CCCCCCEEEEEECCCEEECCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHH
YRADGEFIPPAEFVALAEQGGMIAELDLWVAKRVCQFIQTSHAQGRSLPTLTLNISAFSF
HHCCCCCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECC
GQADFLDALIALTKEHGIVAHQLGIELNEAAFLMQPQFVAERVSKLVDAGIGIVLDHFGS
CCHHHHHHHHHHHHCCCEEEHHHCCEECCHHHEECHHHHHHHHHHHHHCCCCEEEECCCC
GSSALSCLANQPLVAVKLDMSCIDSLATMPQRVKALIVSAQQFNLHVVAKGVESPQHYQA
CHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHH
FVEFGCDGYQGYLFSRALNQVDFIQLVCPRPLLRSV
HHHHCCCCHHHHHHHHHHCHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]