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The map label for this gene is prlC [H]

Identifier: 160877494

GI number: 160877494

Start: 5188221

End: 5190260

Strand: Reverse

Name: prlC [H]

Synonym: Sbal195_4392

Alternate gene names: 160877494

Gene position: 5190260-5188221 (Counterclockwise)

Preceding gene: 160877504

Following gene: 160877493

Centisome position: 97.06

GC content: 49.41

Gene sequence:

>2040_bases
ATGAGCAACCCTTTGCTTAGCGGCGCAAAATTACCGCTTTTTTCACAGATTAAACCGGAACATATTCAAGTCGCCGTTGA
GCATGCCATTGCTCAGTGCCGCACTAAGATTGATGAAGTGCTGCAGAATCAAGGTCCTTACACTTGGGACAACTTGGTCG
CGCCACTAGAACAGGTTGACGATGAGCTAAGCCAAATTTGGTCGCCCGTTTCTCACATGAATTCAGTCACCAGCACCGAT
GAATGGCGCGCTGCTCATGATGCTTGTTTGCCGCTATTGTCGGAATACGGCACCTATGTTGGTCAACACCAAGGTTTGTA
TCAAGCCTATAAAGCCCTGCGTACATCAAATGAATTTACACAGTTAAGCCAAGCCCAGCAGAAGGTGATTGAACACAGCC
TGCGCGATTTTGAACTATCGGGTATTGGCTTAGATGACGCGCAAAAAGTGCGTTATGGCGAAATGGTCAAACGTCTTTCT
GAACTCACCAGTGGCTTTTCGAATCAATTACTGGATGCGACTCAAGCTTGGACTAAGTTGATCACAGATGAAGCGGAACT
TGCTGGCCTGCCAGAGTCTGCCAAAGCCGCCGCTAAGGCGATGGCCGATGCGCGTGAGTTAGACGGTTGGTTGTTTACCT
TAGATTTCCCTTCTTATTTACCTGTCATGACTTACAGCGAAAACCGCAGTCTTCGGGAAGAGTGTTACCGCGCCTTCGTT
ACGCGCGCCTCGGATCAAGGCCCTAATGCTGGCGAGTTTGATAACAGCCCGCTGATGGACGAAATCCTAGCGCTGCGCTA
CGAACTGGCATTGTTACTCGGTTTTGACAGTTTTGCCGACAAATCCCTAGCGACGAAAATGGCTGAAACGCCGGCGCAGG
TGATGGCATTTTTAAATGAGTTAGCGCTGCGCTCAAAGGATCAGGCTAAAGCTGAATTGGCCGAGCTGAGAGCGTTTGCC
GAGACGGAATACGGCGTGAGCGAAATGGCATCTTGGGACTTAAGTTTCTATGCCGAGAAGTTGCAGCAGCATAAGTATGA
GATTTCACAGGAAATCCTGCGTCCTTACTTCCCTGAAGATAAAGTGCTCTCGGGTTTGTTCTACACAGTATCGCGTTTAT
TCGGTCTTAAGATTGTCGAGCAAAAAGACTTTGACCGTTGGCATAAGGACGTGCGTTTCTTCGATATTCATGACGAAACC
GGCGAACACAGAGGCAGTTTCTACCTCGACTTATATGCCCGCACAGGTAAACGTGGCGGGGCTTGGATGGATGACTGCCG
CGTGCGCCGTCAAACCGCCGATGGATTGCAAAAGCCAGTGGCCTATTTGACCTGTAACTTTAATGGACCAGTCGATGGCA
AACCTGCGCTATTTACCCACGATGAAGTGACAACCCTGTTCCACGAATTTGGCCATGGTATCCACCACATGCTGACCAAA
ATCGATGTTGCAGGCGTGTCGGGTATCAATGGTGTGCCTTGGGATGCGGTCGAGTTACCGAGCCAATTTATGGAAAACTG
GTGCTGGCAGGAAGAAGCCTTGGCCGAAATTTCTGGTCACTTCGAAACGGGTGAGCCATTACCTAAAGCCTTGTTAGATA
AGATGCTGGCTGCGAAAAACTTCCAATCTGGCATGATGATGCTGCGCCAACTTGAGTTCTCGTTGTTCGATTTTAGAATG
CACCACGAATACGACCCCGCTAAAGGCGCGCGCATTCAAGAAACCTTAGACGAAGTGCGTCGTCAGGTCGCCGTATTAAC
GCCGCCAGACTTTAACCGTTTCCAACATGGTTTTGCCCACATTTTTGCGGGCGGTTATGCTGCGGGTTATTACAGCTATA
AATGGGCAGAAGTGCTGTCGGCGGATGCGTTTTCCCGCTTCGAAGAGGAAGGGATTTTCAACCCTGAAACAGGTCGTCGT
TTCCTACACAATATCCTCGAAATGGGTGGTTCAGCCGAACCTATGGACTTGTTCAAACAGTTTATGGGACGTGAGCCGAA
TATCGATGCCCTGTTAAGACATTCGGGCATTGCTGCATAA

Upstream 100 bases:

>100_bases
GCGTTAGCAAGGCGTTCGAAGGGGGCAATCGGTTTTCTCGCCTTGATAAATAGCCTGTTAGCCCTTATCTATAAGTGATA
CAGATTGTTGAGGAGTCAAT

Downstream 100 bases:

>100_bases
GCAATTGTTCGCCTTGATAAATCAGCCCATTATAACGGGCTGATTTTCTCTGAGCATTTAGTTTTGCTAAACGATAAAAA
GGCGTCATCTGACGCCTTTT

Product: oligopeptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 679; Mature: 678

Protein sequence:

>679_residues
MSNPLLSGAKLPLFSQIKPEHIQVAVEHAIAQCRTKIDEVLQNQGPYTWDNLVAPLEQVDDELSQIWSPVSHMNSVTSTD
EWRAAHDACLPLLSEYGTYVGQHQGLYQAYKALRTSNEFTQLSQAQQKVIEHSLRDFELSGIGLDDAQKVRYGEMVKRLS
ELTSGFSNQLLDATQAWTKLITDEAELAGLPESAKAAAKAMADARELDGWLFTLDFPSYLPVMTYSENRSLREECYRAFV
TRASDQGPNAGEFDNSPLMDEILALRYELALLLGFDSFADKSLATKMAETPAQVMAFLNELALRSKDQAKAELAELRAFA
ETEYGVSEMASWDLSFYAEKLQQHKYEISQEILRPYFPEDKVLSGLFYTVSRLFGLKIVEQKDFDRWHKDVRFFDIHDET
GEHRGSFYLDLYARTGKRGGAWMDDCRVRRQTADGLQKPVAYLTCNFNGPVDGKPALFTHDEVTTLFHEFGHGIHHMLTK
IDVAGVSGINGVPWDAVELPSQFMENWCWQEEALAEISGHFETGEPLPKALLDKMLAAKNFQSGMMMLRQLEFSLFDFRM
HHEYDPAKGARIQETLDEVRRQVAVLTPPDFNRFQHGFAHIFAGGYAAGYYSYKWAEVLSADAFSRFEEEGIFNPETGRR
FLHNILEMGGSAEPMDLFKQFMGREPNIDALLRHSGIAA

Sequences:

>Translated_679_residues
MSNPLLSGAKLPLFSQIKPEHIQVAVEHAIAQCRTKIDEVLQNQGPYTWDNLVAPLEQVDDELSQIWSPVSHMNSVTSTD
EWRAAHDACLPLLSEYGTYVGQHQGLYQAYKALRTSNEFTQLSQAQQKVIEHSLRDFELSGIGLDDAQKVRYGEMVKRLS
ELTSGFSNQLLDATQAWTKLITDEAELAGLPESAKAAAKAMADARELDGWLFTLDFPSYLPVMTYSENRSLREECYRAFV
TRASDQGPNAGEFDNSPLMDEILALRYELALLLGFDSFADKSLATKMAETPAQVMAFLNELALRSKDQAKAELAELRAFA
ETEYGVSEMASWDLSFYAEKLQQHKYEISQEILRPYFPEDKVLSGLFYTVSRLFGLKIVEQKDFDRWHKDVRFFDIHDET
GEHRGSFYLDLYARTGKRGGAWMDDCRVRRQTADGLQKPVAYLTCNFNGPVDGKPALFTHDEVTTLFHEFGHGIHHMLTK
IDVAGVSGINGVPWDAVELPSQFMENWCWQEEALAEISGHFETGEPLPKALLDKMLAAKNFQSGMMMLRQLEFSLFDFRM
HHEYDPAKGARIQETLDEVRRQVAVLTPPDFNRFQHGFAHIFAGGYAAGYYSYKWAEVLSADAFSRFEEEGIFNPETGRR
FLHNILEMGGSAEPMDLFKQFMGREPNIDALLRHSGIAA
>Mature_678_residues
SNPLLSGAKLPLFSQIKPEHIQVAVEHAIAQCRTKIDEVLQNQGPYTWDNLVAPLEQVDDELSQIWSPVSHMNSVTSTDE
WRAAHDACLPLLSEYGTYVGQHQGLYQAYKALRTSNEFTQLSQAQQKVIEHSLRDFELSGIGLDDAQKVRYGEMVKRLSE
LTSGFSNQLLDATQAWTKLITDEAELAGLPESAKAAAKAMADARELDGWLFTLDFPSYLPVMTYSENRSLREECYRAFVT
RASDQGPNAGEFDNSPLMDEILALRYELALLLGFDSFADKSLATKMAETPAQVMAFLNELALRSKDQAKAELAELRAFAE
TEYGVSEMASWDLSFYAEKLQQHKYEISQEILRPYFPEDKVLSGLFYTVSRLFGLKIVEQKDFDRWHKDVRFFDIHDETG
EHRGSFYLDLYARTGKRGGAWMDDCRVRRQTADGLQKPVAYLTCNFNGPVDGKPALFTHDEVTTLFHEFGHGIHHMLTKI
DVAGVSGINGVPWDAVELPSQFMENWCWQEEALAEISGHFETGEPLPKALLDKMLAAKNFQSGMMMLRQLEFSLFDFRMH
HEYDPAKGARIQETLDEVRRQVAVLTPPDFNRFQHGFAHIFAGGYAAGYYSYKWAEVLSADAFSRFEEEGIFNPETGRRF
LHNILEMGGSAEPMDLFKQFMGREPNIDALLRHSGIAA

Specific function: May play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. Can cleave N-acetyl-L-Ala(4) [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI14149738, Length=673, Percent_Identity=31.9465081723626, Blast_Score=300, Evalue=4e-81,
Organism=Homo sapiens, GI4507491, Length=611, Percent_Identity=31.2602291325696, Blast_Score=285, Evalue=9e-77,
Organism=Homo sapiens, GI156105687, Length=682, Percent_Identity=25.2199413489736, Blast_Score=189, Evalue=1e-47,
Organism=Escherichia coli, GI1789913, Length=678, Percent_Identity=65.4867256637168, Blast_Score=923, Evalue=0.0,
Organism=Escherichia coli, GI1787819, Length=688, Percent_Identity=32.703488372093, Blast_Score=315, Evalue=8e-87,
Organism=Caenorhabditis elegans, GI71999758, Length=570, Percent_Identity=25.7894736842105, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI32565901, Length=628, Percent_Identity=23.8853503184713, Blast_Score=117, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319793, Length=686, Percent_Identity=28.4256559766764, Blast_Score=279, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6322715, Length=699, Percent_Identity=23.3190271816881, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21356111, Length=585, Percent_Identity=29.4017094017094, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI20129717, Length=592, Percent_Identity=24.4932432432432, Blast_Score=160, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.24.70 [H]

Molecular weight: Translated: 76916; Mature: 76785

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPLLSGAKLPLFSQIKPEHIQVAVEHAIAQCRTKIDEVLQNQGPYTWDNLVAPLEQVD
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
DELSQIWSPVSHMNSVTSTDEWRAAHDACLPLLSEYGTYVGQHQGLYQAYKALRTSNEFT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
QLSQAQQKVIEHSLRDFELSGIGLDDAQKVRYGEMVKRLSELTSGFSNQLLDATQAWTKL
HHHHHHHHHHHHHHHHCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITDEAELAGLPESAKAAAKAMADARELDGWLFTLDFPSYLPVMTYSENRSLREECYRAFV
HCCCHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCCCHHHHHHHHHHH
TRASDQGPNAGEFDNSPLMDEILALRYELALLLGFDSFADKSLATKMAETPAQVMAFLNE
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHH
LALRSKDQAKAELAELRAFAETEYGVSEMASWDLSFYAEKLQQHKYEISQEILRPYFPED
HHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
KVLSGLFYTVSRLFGLKIVEQKDFDRWHKDVRFFDIHDETGEHRGSFYLDLYARTGKRGG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEEECCCCCCC
AWMDDCRVRRQTADGLQKPVAYLTCNFNGPVDGKPALFTHDEVTTLFHEFGHGIHHMLTK
CCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHH
IDVAGVSGINGVPWDAVELPSQFMENWCWQEEALAEISGHFETGEPLPKALLDKMLAAKN
HHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
FQSGMMMLRQLEFSLFDFRMHHEYDPAKGARIQETLDEVRRQVAVLTPPDFNRFQHGFAH
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEECCCCCHHHHHHHHHH
IFAGGYAAGYYSYKWAEVLSADAFSRFEEEGIFNPETGRRFLHNILEMGGSAEPMDLFKQ
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHH
FMGREPNIDALLRHSGIAA
HHCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
SNPLLSGAKLPLFSQIKPEHIQVAVEHAIAQCRTKIDEVLQNQGPYTWDNLVAPLEQVD
CCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
DELSQIWSPVSHMNSVTSTDEWRAAHDACLPLLSEYGTYVGQHQGLYQAYKALRTSNEFT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
QLSQAQQKVIEHSLRDFELSGIGLDDAQKVRYGEMVKRLSELTSGFSNQLLDATQAWTKL
HHHHHHHHHHHHHHHHCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITDEAELAGLPESAKAAAKAMADARELDGWLFTLDFPSYLPVMTYSENRSLREECYRAFV
HCCCHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCCCHHHHHHHHHHH
TRASDQGPNAGEFDNSPLMDEILALRYELALLLGFDSFADKSLATKMAETPAQVMAFLNE
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHH
LALRSKDQAKAELAELRAFAETEYGVSEMASWDLSFYAEKLQQHKYEISQEILRPYFPED
HHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
KVLSGLFYTVSRLFGLKIVEQKDFDRWHKDVRFFDIHDETGEHRGSFYLDLYARTGKRGG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEEECCCCCCC
AWMDDCRVRRQTADGLQKPVAYLTCNFNGPVDGKPALFTHDEVTTLFHEFGHGIHHMLTK
CCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHH
IDVAGVSGINGVPWDAVELPSQFMENWCWQEEALAEISGHFETGEPLPKALLDKMLAAKN
HHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
FQSGMMMLRQLEFSLFDFRMHHEYDPAKGARIQETLDEVRRQVAVLTPPDFNRFQHGFAH
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEECCCCCHHHHHHHHHH
IFAGGYAAGYYSYKWAEVLSADAFSRFEEEGIFNPETGRRFLHNILEMGGSAEPMDLFKQ
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHH
FMGREPNIDALLRHSGIAA
HHCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]