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The map label for this gene is hemN [H]

Identifier: 160877341

GI number: 160877341

Start: 5016860

End: 5018197

Strand: Direct

Name: hemN [H]

Synonym: Sbal195_4239

Alternate gene names: 160877341

Gene position: 5016860-5018197 (Clockwise)

Preceding gene: 160877339

Following gene: 160877342

Centisome position: 93.82

GC content: 47.46

Gene sequence:

>1338_bases
ATGTCTTCAGTTATCCAAACGCTCAGCGGCGCTATCGCAACGCCTTATCAAGCGAATATTACCGTCCCTAACTGGATGCT
CGGCTCGATGGAACGAGTCATGCAGTACTACGTCGATAAGAATCTTCGCCTCGATACCCTTTCCGCAGAAATGATGCCAG
CGCCCGTAGAAGGCAAAAAGTATATGCTGTACGCGCATATCCCCTTCTGCCATACCCTGTGTTCTTACTGCACCTTCCAC
CGTTTCATGTTCAAGGAAGACAAGGCACGCGCCTATTTCATCTCATTGCGTAAAGAGATGGAAATGGTCAAAGCCCTCGG
CTATGACTTTGAATCTATGTACATTGGCGGCGGCACCACCACAGTATTAGAAGATGAATTAGCCCGTACTATCGAACACG
CGAAAACCCTATTCCCGAGCATTAAAGAAGTCTCCTGCGAGTCCGATCCGCAGCATTTAGATAGCCCTGGCTTTAAGCAA
CTCAAAGGCCTAGTGGATCGCATGTCCATCGGCGTGCAAAGCTTTAATGACGATATTTTAAAAATGACCGACCGACTCGA
TAAGTTCGGTACGGGTCAACAAACCTTCGACAAGATCATGGGCGCCAAAGAGTTGTTCCCAATTATCAACGTCGATCTGA
TTTTTGGTTTCCGCGGCCAAACCGATGAAGTGATCCAACACGATCTCGACATGGCATCGCGTTTAGATCCAAGACAAATT
ACCACTTATCCGCTGATGATCACCCACCAGACTCGCAAGAGTGTAAAAGGCAAGTTAGCGGCTCCGCAGGCGGATATGGC
CAACCAATATCGCCAGATCTTAAACAGCCTGAATGGCCAATATAATCAATTGTCTGCATGGGCATTTGGTAAAACCGATG
ACGAAGGATTTGACGAATACGTTATCGATTACGACGAGTATTTAGGCGTAGGTTCAGGCTCATTCAGCTTCTTGAATGAT
ACCCTATATGTAAACACTTTCTCGTTGCGCAAGTACCAAGAACGCATTGCCGCCGGCCACATGGGTGTCGAGCAGCAAAA
GAACTACAGCAAAAAAGACGTGATGCAATACCGCTTCTTGCTGGGCATGTTCTCCGGCCGTTTATCACGTAAATATTTCC
GCGACACCTTTGGCGTCAACTTAGATACCGCCTTGTTTAAAGAAATGACGTCGATGAAGTTAATTGGTGCGATCAAGAAT
GACCCAAGGGATCCCGACAATCTGATCGTGACCGACAACGGCAAGATGATGGGTCTCTTGATGATGAAAGAGTTTTATTC
AGGCATGGACAACGTGCGCGCCCAGTTGCGTAAACCGCTCAAACCCTGTGATATGTAA

Upstream 100 bases:

>100_bases
TTAACAATTACATACGATGTAGTCTTATTGCGCTAGGTGGTCGTGAATTACCTAAAGCAATTTCGGTGTTTACGGTTAGC
ACTCACAGATAGGAATCGTT

Downstream 100 bases:

>100_bases
CACTTACGGATGATTGTTGATTCATAAAGACTAAACAGGCCCTTCGAGGGCCTTTTTGTTAACTTGGTTTAAAGGTAGTC
TTGCCTTAATGCTAGCTTGA

Product: coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSSVIQTLSGAIATPYQANITVPNWMLGSMERVMQYYVDKNLRLDTLSAEMMPAPVEGKKYMLYAHIPFCHTLCSYCTFH
RFMFKEDKARAYFISLRKEMEMVKALGYDFESMYIGGGTTTVLEDELARTIEHAKTLFPSIKEVSCESDPQHLDSPGFKQ
LKGLVDRMSIGVQSFNDDILKMTDRLDKFGTGQQTFDKIMGAKELFPIINVDLIFGFRGQTDEVIQHDLDMASRLDPRQI
TTYPLMITHQTRKSVKGKLAAPQADMANQYRQILNSLNGQYNQLSAWAFGKTDDEGFDEYVIDYDEYLGVGSGSFSFLND
TLYVNTFSLRKYQERIAAGHMGVEQQKNYSKKDVMQYRFLLGMFSGRLSRKYFRDTFGVNLDTALFKEMTSMKLIGAIKN
DPRDPDNLIVTDNGKMMGLLMMKEFYSGMDNVRAQLRKPLKPCDM

Sequences:

>Translated_445_residues
MSSVIQTLSGAIATPYQANITVPNWMLGSMERVMQYYVDKNLRLDTLSAEMMPAPVEGKKYMLYAHIPFCHTLCSYCTFH
RFMFKEDKARAYFISLRKEMEMVKALGYDFESMYIGGGTTTVLEDELARTIEHAKTLFPSIKEVSCESDPQHLDSPGFKQ
LKGLVDRMSIGVQSFNDDILKMTDRLDKFGTGQQTFDKIMGAKELFPIINVDLIFGFRGQTDEVIQHDLDMASRLDPRQI
TTYPLMITHQTRKSVKGKLAAPQADMANQYRQILNSLNGQYNQLSAWAFGKTDDEGFDEYVIDYDEYLGVGSGSFSFLND
TLYVNTFSLRKYQERIAAGHMGVEQQKNYSKKDVMQYRFLLGMFSGRLSRKYFRDTFGVNLDTALFKEMTSMKLIGAIKN
DPRDPDNLIVTDNGKMMGLLMMKEFYSGMDNVRAQLRKPLKPCDM
>Mature_444_residues
SSVIQTLSGAIATPYQANITVPNWMLGSMERVMQYYVDKNLRLDTLSAEMMPAPVEGKKYMLYAHIPFCHTLCSYCTFHR
FMFKEDKARAYFISLRKEMEMVKALGYDFESMYIGGGTTTVLEDELARTIEHAKTLFPSIKEVSCESDPQHLDSPGFKQL
KGLVDRMSIGVQSFNDDILKMTDRLDKFGTGQQTFDKIMGAKELFPIINVDLIFGFRGQTDEVIQHDLDMASRLDPRQIT
TYPLMITHQTRKSVKGKLAAPQADMANQYRQILNSLNGQYNQLSAWAFGKTDDEGFDEYVIDYDEYLGVGSGSFSFLNDT
LYVNTFSLRKYQERIAAGHMGVEQQKNYSKKDVMQYRFLLGMFSGRLSRKYFRDTFGVNLDTALFKEMTSMKLIGAIKND
PRDPDNLIVTDNGKMMGLLMMKEFYSGMDNVRAQLRKPLKPCDM

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=287, Percent_Identity=25.7839721254355, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI87082341, Length=300, Percent_Identity=26.3333333333333, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1789325, Length=266, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 50908; Mature: 50777

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVIQTLSGAIATPYQANITVPNWMLGSMERVMQYYVDKNLRLDTLSAEMMPAPVEGKK
CCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHCCCCCCCCE
YMLYAHIPFCHTLCSYCTFHRFMFKEDKARAYFISLRKEMEMVKALGYDFESMYIGGGTT
EEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCH
TVLEDELARTIEHAKTLFPSIKEVSCESDPQHLDSPGFKQLKGLVDRMSIGVQSFNDDIL
HHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHH
KMTDRLDKFGTGQQTFDKIMGAKELFPIINVDLIFGFRGQTDEVIQHDLDMASRLDPRQI
HHHHHHHHCCCCHHHHHHHHCHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCE
TTYPLMITHQTRKSVKGKLAAPQADMANQYRQILNSLNGQYNQLSAWAFGKTDDEGFDEY
EEEEEEEEECHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHH
VIDYDEYLGVGSGSFSFLNDTLYVNTFSLRKYQERIAAGHMGVEQQKNYSKKDVMQYRFL
HCCHHHHHCCCCCCCHHHCCEEEEEEHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHH
LGMFSGRLSRKYFRDTFGVNLDTALFKEMTSMKLIGAIKNDPRDPDNLIVTDNGKMMGLL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHH
MMKEFYSGMDNVRAQLRKPLKPCDM
HHHHHHCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SSVIQTLSGAIATPYQANITVPNWMLGSMERVMQYYVDKNLRLDTLSAEMMPAPVEGKK
CHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHCCCCCCCCE
YMLYAHIPFCHTLCSYCTFHRFMFKEDKARAYFISLRKEMEMVKALGYDFESMYIGGGTT
EEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCH
TVLEDELARTIEHAKTLFPSIKEVSCESDPQHLDSPGFKQLKGLVDRMSIGVQSFNDDIL
HHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHH
KMTDRLDKFGTGQQTFDKIMGAKELFPIINVDLIFGFRGQTDEVIQHDLDMASRLDPRQI
HHHHHHHHCCCCHHHHHHHHCHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCE
TTYPLMITHQTRKSVKGKLAAPQADMANQYRQILNSLNGQYNQLSAWAFGKTDDEGFDEY
EEEEEEEEECHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHH
VIDYDEYLGVGSGSFSFLNDTLYVNTFSLRKYQERIAAGHMGVEQQKNYSKKDVMQYRFL
HCCHHHHHCCCCCCCHHHCCEEEEEEHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHH
LGMFSGRLSRKYFRDTFGVNLDTALFKEMTSMKLIGAIKNDPRDPDNLIVTDNGKMMGLL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHH
MMKEFYSGMDNVRAQLRKPLKPCDM
HHHHHHCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8757728; 8969508; 9384377; 1339421 [H]