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The map label for this gene is hemY [H]

Identifier: 160877201

GI number: 160877201

Start: 4830317

End: 4831483

Strand: Direct

Name: hemY [H]

Synonym: Sbal195_4097

Alternate gene names: 160877201

Gene position: 4830317-4831483 (Clockwise)

Preceding gene: 160877200

Following gene: 160877202

Centisome position: 90.33

GC content: 48.33

Gene sequence:

>1167_bases
ATGATCAAAATATTAATTTTATTAGGGATAGTGCTAATAGGGCTCTGTATCAGCCCTTGGTTGGTTGGTAATACAGGTTA
TGTCTATATCGCTGCCGGTGACTACCAGATTGAGACCAGCTTAGTCTTTGGGATCATTGCGTTAATTGTATTTTATGCCG
TATTCCAAGTACTCGAATGGCTAGTGATTAGCGCCATCAATCTGATGCTGCGCAGTCGTTTTATTCCCCATCACTGGCGC
CGCCGCTCGGCTAAAAAACATACCTTAATGGGTGCACTGGCTCTGGCTGAAGAAGATTGGCCTGCAGCAGAACGCGCCAT
GATAAAAGGCGCTGACAATGGCGAACTCCCTGCGCTTAACTTACTGGCAGCGGCCCGTGCCGCTCAGTATCAACAAAAAA
TAGGCGAGCGAGATCAATATCTTGATCGCGCTGCAGCGCAACCTCTTGCCGCGAATGCCGTCGCAACCACTCGCACTCGA
TACCTCTTAAAGCAAGGGGAATTAGCCCTAGCCCGCACCGAGCTGGATAAATTAGCACCGACGAGCAAGAGTAAAGCGCC
AGTACTCAAACTCGCCCTTGAGTTATACCGAACCCAAGAGGATTGGGATGCGCTCAAGCTATTAATACCTATTTTGAAGA
AGCGTCAGATCCTCGATGATGCTCAGCTGAATGAGCTCAATATCGCCACAAATTGCGCGTTACTCAAAGCCGCAGCCATC
AAAGGTGAAGAAGCCTTAGAGCAATGCTGGCAGTGGTTATCCCGCAGTGAACGCAATCAATCTGAGTTTCTGGCGATTTA
TGCCATGGGTTTATGCCGCTTTAATCGCAAAGAGCAAGCGCTGAAACTAATCGCGAAAAAGTTACGAACCTCTCCCGAGT
CAGCAGTTTTAACAGCAATTCCTGAAATTGCGACAGCCCAAGACACAGAGATCCGTAAACAGTTACTCAAGCATGAAGTC
ACCCATGAGAATAATGCGGACTACCAGATGTGTTTGGCTAAGCTTTATCAGCAAACGCGGGATATGAAAGAAGCCAAAAG
CTGCTGGCAGAATGTGTGCCGACTCGAACCAACAAAAGCCTCTTGGTTGGCGCTCGCACGGATTCAAGAACAGTTAGGCG
AACAAGGTAACGCCAATCAGAGCTACCGTCAGGCAGTTAACCTGTAG

Upstream 100 bases:

>100_bases
TAGAACTTGATCCTATTACCCTGAAATCCTTTGCAGCTAAACCTCTGTTATTACAGCTGACTAGTTATGGCGAGCTGACC
TCATCAGAGGATGCGCCACT

Downstream 100 bases:

>100_bases
CTCTACGACATCAATAATGATAACGCCGTGATTAGCACTGTGGTGAGTCACGGCGTTTACCACTCACGAAAGTTCTTGCT
TCGTTTCTACTCAAAAACGT

Product: HemY domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MIKILILLGIVLIGLCISPWLVGNTGYVYIAAGDYQIETSLVFGIIALIVFYAVFQVLEWLVISAINLMLRSRFIPHHWR
RRSAKKHTLMGALALAEEDWPAAERAMIKGADNGELPALNLLAAARAAQYQQKIGERDQYLDRAAAQPLAANAVATTRTR
YLLKQGELALARTELDKLAPTSKSKAPVLKLALELYRTQEDWDALKLLIPILKKRQILDDAQLNELNIATNCALLKAAAI
KGEEALEQCWQWLSRSERNQSEFLAIYAMGLCRFNRKEQALKLIAKKLRTSPESAVLTAIPEIATAQDTEIRKQLLKHEV
THENNADYQMCLAKLYQQTRDMKEAKSCWQNVCRLEPTKASWLALARIQEQLGEQGNANQSYRQAVNL

Sequences:

>Translated_388_residues
MIKILILLGIVLIGLCISPWLVGNTGYVYIAAGDYQIETSLVFGIIALIVFYAVFQVLEWLVISAINLMLRSRFIPHHWR
RRSAKKHTLMGALALAEEDWPAAERAMIKGADNGELPALNLLAAARAAQYQQKIGERDQYLDRAAAQPLAANAVATTRTR
YLLKQGELALARTELDKLAPTSKSKAPVLKLALELYRTQEDWDALKLLIPILKKRQILDDAQLNELNIATNCALLKAAAI
KGEEALEQCWQWLSRSERNQSEFLAIYAMGLCRFNRKEQALKLIAKKLRTSPESAVLTAIPEIATAQDTEIRKQLLKHEV
THENNADYQMCLAKLYQQTRDMKEAKSCWQNVCRLEPTKASWLALARIQEQLGEQGNANQSYRQAVNL
>Mature_388_residues
MIKILILLGIVLIGLCISPWLVGNTGYVYIAAGDYQIETSLVFGIIALIVFYAVFQVLEWLVISAINLMLRSRFIPHHWR
RRSAKKHTLMGALALAEEDWPAAERAMIKGADNGELPALNLLAAARAAQYQQKIGERDQYLDRAAAQPLAANAVATTRTR
YLLKQGELALARTELDKLAPTSKSKAPVLKLALELYRTQEDWDALKLLIPILKKRQILDDAQLNELNIATNCALLKAAAI
KGEEALEQCWQWLSRSERNQSEFLAIYAMGLCRFNRKEQALKLIAKKLRTSPESAVLTAIPEIATAQDTEIRKQLLKHEV
THENNADYQMCLAKLYQQTRDMKEAKSCWQNVCRLEPTKASWLALARIQEQLGEQGNANQSYRQAVNL

Specific function: Involved in a late step of protoheme IX synthesis [H]

COG id: COG3071

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1790234, Length=310, Percent_Identity=31.9354838709677, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010817
- InterPro:   IPR005254
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR013105
- InterPro:   IPR019734 [H]

Pfam domain/function: PF07219 HemY_N; PF07719 TPR_2 [H]

EC number: NA

Molecular weight: Translated: 43705; Mature: 43705

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKILILLGIVLIGLCISPWLVGNTGYVYIAAGDYQIETSLVFGIIALIVFYAVFQVLEW
CHHHHHHHHHHHHHHHHCCCEECCCCEEEEEECCEEHHHHHHHHHHHHHHHHHHHHHHHH
LVISAINLMLRSRFIPHHWRRRSAKKHTLMGALALAEEDWPAAERAMIKGADNGELPALN
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHH
LLAAARAAQYQQKIGERDQYLDRAAAQPLAANAVATTRTRYLLKQGELALARTELDKLAP
HHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
TSKSKAPVLKLALELYRTQEDWDALKLLIPILKKRQILDDAQLNELNIATNCALLKAAAI
CCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHC
KGEEALEQCWQWLSRSERNQSEFLAIYAMGLCRFNRKEQALKLIAKKLRTSPESAVLTAI
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHC
PEIATAQDTEIRKQLLKHEVTHENNADYQMCLAKLYQQTRDMKEAKSCWQNVCRLEPTKA
CHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
SWLALARIQEQLGEQGNANQSYRQAVNL
HHHHHHHHHHHHCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MIKILILLGIVLIGLCISPWLVGNTGYVYIAAGDYQIETSLVFGIIALIVFYAVFQVLEW
CHHHHHHHHHHHHHHHHCCCEECCCCEEEEEECCEEHHHHHHHHHHHHHHHHHHHHHHHH
LVISAINLMLRSRFIPHHWRRRSAKKHTLMGALALAEEDWPAAERAMIKGADNGELPALN
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHH
LLAAARAAQYQQKIGERDQYLDRAAAQPLAANAVATTRTRYLLKQGELALARTELDKLAP
HHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
TSKSKAPVLKLALELYRTQEDWDALKLLIPILKKRQILDDAQLNELNIATNCALLKAAAI
CCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHC
KGEEALEQCWQWLSRSERNQSEFLAIYAMGLCRFNRKEQALKLIAKKLRTSPESAVLTAI
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHC
PEIATAQDTEIRKQLLKHEVTHENNADYQMCLAKLYQQTRDMKEAKSCWQNVCRLEPTKA
CHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
SWLALARIQEQLGEQGNANQSYRQAVNL
HHHHHHHHHHHHCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]