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The map label for this gene is emrK [H]

Identifier: 160877073

GI number: 160877073

Start: 4673535

End: 4674593

Strand: Reverse

Name: emrK [H]

Synonym: Sbal195_3969

Alternate gene names: 160877073

Gene position: 4674593-4673535 (Counterclockwise)

Preceding gene: 160877076

Following gene: 160877072

Centisome position: 87.42

GC content: 50.14

Gene sequence:

>1059_bases
ATGTCCAAAAGTAAACTCATTATCGCCGTTCCACTGTTACTCGCTGCGGTTGCGGGAGGCGGTTATTACTGGTGGACACA
GGTACGTTTTATCGAAACCACTGATAACGCTTATGTTGAGGCCGATATTTCCCATATTAGCGTTAAAGTGCCCGGCTACG
TCGTGTTAAGCGATGTGACCGATAACCAGCATGTGCAAAAGGGTGAGTTATTAGCTCAGCTCGAAGATAACCAATTTAGC
GCCAAAGTGAGTCAAGCCGAAGCCTCACTGGCAAGTTCGAAGGCGGACTTGCAAACCCTAGCCGCTAAGGTGGAGTTACA
ACGGGCGTTAATCACCCAAGCCAGTGCCGGTGTCGTGGCGGCTGAGTCCGATAAAATACGTGCACAGCAACAATTGAGCC
GCTCGAAAAAGCTTAAAGTCAGTAATTACAGCTCTCAAGATGATGTCGATCAACTGCAAGCGGGATTCGATTCTGCCGCC
GCACGTCTCGATGAAGCCAAAGCCGTGTTAGTGGCAAAGCAACGCGAGTTAGCGGTTTTTAATGCCCAATTAGATCAGGC
GGGTTCTGTGGTAGAACAGGCCGATGCGACCTTAGAATTGGCGAAAATTCAATTAAATGATACCCGTGTGACCGCACCTT
TTTCTGGGGTGATTGGTAAACGTGGCGCTATGGTGGGGCAGTACGTGCAGCCCGGCCAAGCACTCTACAGTTTGGTTCCG
GATGGGGCTGTGTGGATCACGGCGAACTTTAAAGAGACCCAGATCCAACATATGCAACCAGGACAGTCGGTGCAGGTCAG
TCTCGATGCGTTTCCCGACAAAACCTTTATAGGTGTTATCGATAGTCTGTCACCGGCGTCCGGAGCCAAATTCAGTTTAC
TGCCGGCGGAAAATGCTACAGGTAACTTCACTAAAATCGTGCAACGTATTCCCGTGCGTATTCGCTTAGATTTATCTGAG
GCAGAAGCACACATGCTACCGGGCTTAAGTGCGGTCGTGAAAGTGGATACGGCGTCGGGTACTGCAATATCGGCAATCGC
AGCAAATACAGGTCGTTAG

Upstream 100 bases:

>100_bases
CATCATTGTTACACCTGTGAAACAGTGGGTTGATTTTTTACTGGCTAATAAACTTAGTGAGACAGTAGTACACTAGATAT
CACTAATCAAGGAGTCATTC

Downstream 100 bases:

>100_bases
TATGAGCGCAACCGGCTCTATTACTGCGTCTGCCGATATGGAGGCGCAGGGCATCAGTGTCCCTCACAAGCCTACTGATT
ATGAGCGTGGCAGTCGCCGC

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSKSKLIIAVPLLLAAVAGGGYYWWTQVRFIETTDNAYVEADISHISVKVPGYVVLSDVTDNQHVQKGELLAQLEDNQFS
AKVSQAEASLASSKADLQTLAAKVELQRALITQASAGVVAAESDKIRAQQQLSRSKKLKVSNYSSQDDVDQLQAGFDSAA
ARLDEAKAVLVAKQRELAVFNAQLDQAGSVVEQADATLELAKIQLNDTRVTAPFSGVIGKRGAMVGQYVQPGQALYSLVP
DGAVWITANFKETQIQHMQPGQSVQVSLDAFPDKTFIGVIDSLSPASGAKFSLLPAENATGNFTKIVQRIPVRIRLDLSE
AEAHMLPGLSAVVKVDTASGTAISAIAANTGR

Sequences:

>Translated_352_residues
MSKSKLIIAVPLLLAAVAGGGYYWWTQVRFIETTDNAYVEADISHISVKVPGYVVLSDVTDNQHVQKGELLAQLEDNQFS
AKVSQAEASLASSKADLQTLAAKVELQRALITQASAGVVAAESDKIRAQQQLSRSKKLKVSNYSSQDDVDQLQAGFDSAA
ARLDEAKAVLVAKQRELAVFNAQLDQAGSVVEQADATLELAKIQLNDTRVTAPFSGVIGKRGAMVGQYVQPGQALYSLVP
DGAVWITANFKETQIQHMQPGQSVQVSLDAFPDKTFIGVIDSLSPASGAKFSLLPAENATGNFTKIVQRIPVRIRLDLSE
AEAHMLPGLSAVVKVDTASGTAISAIAANTGR
>Mature_351_residues
SKSKLIIAVPLLLAAVAGGGYYWWTQVRFIETTDNAYVEADISHISVKVPGYVVLSDVTDNQHVQKGELLAQLEDNQFSA
KVSQAEASLASSKADLQTLAAKVELQRALITQASAGVVAAESDKIRAQQQLSRSKKLKVSNYSSQDDVDQLQAGFDSAAA
RLDEAKAVLVAKQRELAVFNAQLDQAGSVVEQADATLELAKIQLNDTRVTAPFSGVIGKRGAMVGQYVQPGQALYSLVPD
GAVWITANFKETQIQHMQPGQSVQVSLDAFPDKTFIGVIDSLSPASGAKFSLLPAENATGNFTKIVQRIPVRIRLDLSEA
EAHMLPGLSAVVKVDTASGTAISAIAANTGR

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=331, Percent_Identity=34.441087613293, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1789041, Length=323, Percent_Identity=33.1269349845201, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1790519, Length=312, Percent_Identity=28.525641025641, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI87081951, Length=339, Percent_Identity=24.188790560472, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790024, Length=280, Percent_Identity=25.7142857142857, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789637, Length=339, Percent_Identity=23.3038348082596, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787013, Length=348, Percent_Identity=26.1494252873563, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790012, Length=241, Percent_Identity=26.5560165975104, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 37463; Mature: 37332

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSKLIIAVPLLLAAVAGGGYYWWTQVRFIETTDNAYVEADISHISVKVPGYVVLSDVT
CCCCCEEEEHHHHHHHHCCCCEEEEEEEEEEEECCCEEEEEEEEEEEEECCCEEEEEECC
DNQHVQKGELLAQLEDNQFSAKVSQAEASLASSKADLQTLAAKVELQRALITQASAGVVA
CCCCCCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
AESDKIRAQQQLSRSKKLKVSNYSSQDDVDQLQAGFDSAAARLDEAKAVLVAKQRELAVF
ECCHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHCHHHHHHHHHHHHEEEEECCCEEEEE
NAQLDQAGSVVEQADATLELAKIQLNDTRVTAPFSGVIGKRGAMVGQYVQPGQALYSLVP
ECCHHHHHHHHHHCCCEEEEEEEEECCCEEECCHHHHHCCCCCHHCCCCCCCHHHHHHCC
DGAVWITANFKETQIQHMQPGQSVQVSLDAFPDKTFIGVIDSLSPASGAKFSLLPAENAT
CCEEEEEECCCHHHHHHCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCEEEEEECCCCC
GNFTKIVQRIPVRIRLDLSEAEAHMLPGLSAVVKVDTASGTAISAIAANTGR
CHHHHHHHHCCEEEEEECCHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCC
>Mature Secondary Structure 
SKSKLIIAVPLLLAAVAGGGYYWWTQVRFIETTDNAYVEADISHISVKVPGYVVLSDVT
CCCCEEEEHHHHHHHHCCCCEEEEEEEEEEEECCCEEEEEEEEEEEEECCCEEEEEECC
DNQHVQKGELLAQLEDNQFSAKVSQAEASLASSKADLQTLAAKVELQRALITQASAGVVA
CCCCCCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
AESDKIRAQQQLSRSKKLKVSNYSSQDDVDQLQAGFDSAAARLDEAKAVLVAKQRELAVF
ECCHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHCHHHHHHHHHHHHEEEEECCCEEEEE
NAQLDQAGSVVEQADATLELAKIQLNDTRVTAPFSGVIGKRGAMVGQYVQPGQALYSLVP
ECCHHHHHHHHHHCCCEEEEEEEEECCCEEECCHHHHHCCCCCHHCCCCCCCHHHHHHCC
DGAVWITANFKETQIQHMQPGQSVQVSLDAFPDKTFIGVIDSLSPASGAKFSLLPAENAT
CCEEEEEECCCHHHHHHCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCEEEEEECCCCC
GNFTKIVQRIPVRIRLDLSEAEAHMLPGLSAVVKVDTASGTAISAIAANTGR
CHHHHHHHHCCEEEEEECCHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]