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The map label for this gene is arsR [H]

Identifier: 160877064

GI number: 160877064

Start: 4664966

End: 4665310

Strand: Reverse

Name: arsR [H]

Synonym: Sbal195_3960

Alternate gene names: 160877064

Gene position: 4665310-4664966 (Counterclockwise)

Preceding gene: 160877065

Following gene: 160877063

Centisome position: 87.25

GC content: 50.43

Gene sequence:

>345_bases
ATGCAACCTGTCGCATTTTTTAAGGCACTTGCCGATGAGACTCGGCTTAAATGCCTACTGCTGATCCAGCGTGAAGGTGA
ATTATGTGTGTGTGAGCTGATGGCTGCACTGTCTGAGAGTCAGCCTAAGGTCTCGCGCCATTTGGCTCAGTTGAAAAAGG
CTGGATTGTTGGTCGATAGGCGCCAAGGTCAATGGGTGTTTTATCGGATCAATGCTGAGATCGCGCCTTGGTGCCAGCAG
GTACTTGGCCAAACCTGTGATGATAACGACAGCTTTTTGCAGGATAACGTGCGTAATCTTTGTCAGATGGGCGGTCGACC
CGATCGCCTTAAGGCTTGCTGCTAA

Upstream 100 bases:

>100_bases
CAATACATCTCACATTTCTGTAAAAAATAACTCAAAATATACGTTTTTTCATATATATTATTTACCATATGTATATTCCA
ATCAACTTTGGGAGCAATCG

Downstream 100 bases:

>100_bases
GTTGAAAATAGGTGTGTGATATTTTCTATTAGGATAAGAGTTATTTGAGGCAGTTATGGGAATTTTTGAGCGTTATTTAA
GTGTTTGGGTAGGGCTGAGT

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MQPVAFFKALADETRLKCLLLIQREGELCVCELMAALSESQPKVSRHLAQLKKAGLLVDRRQGQWVFYRINAEIAPWCQQ
VLGQTCDDNDSFLQDNVRNLCQMGGRPDRLKACC

Sequences:

>Translated_114_residues
MQPVAFFKALADETRLKCLLLIQREGELCVCELMAALSESQPKVSRHLAQLKKAGLLVDRRQGQWVFYRINAEIAPWCQQ
VLGQTCDDNDSFLQDNVRNLCQMGGRPDRLKACC
>Mature_114_residues
MQPVAFFKALADETRLKCLLLIQREGELCVCELMAALSESQPKVSRHLAQLKKAGLLVDRRQGQWVFYRINAEIAPWCQQ
VLGQTCDDNDSFLQDNVRNLCQMGGRPDRLKACC

Specific function: Transcriptional repressor for the arsEFG operon. ArsE is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsE is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=111, Percent_Identity=45.945945945946, Blast_Score=103, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12955; Mature: 12955

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
9.6 %Cys+Met (Translated Protein)
7.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
9.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPVAFFKALADETRLKCLLLIQREGELCVCELMAALSESQPKVSRHLAQLKKAGLLVDR
CCHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEC
RQGQWVFYRINAEIAPWCQQVLGQTCDDNDSFLQDNVRNLCQMGGRPDRLKACC
CCCCEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQPVAFFKALADETRLKCLLLIQREGELCVCELMAALSESQPKVSRHLAQLKKAGLLVDR
CCHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEC
RQGQWVFYRINAEIAPWCQQVLGQTCDDNDSFLQDNVRNLCQMGGRPDRLKACC
CCCCEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721697; 8041620; 9278503 [H]