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The map label for this gene is plsC [H]

Identifier: 160877026

GI number: 160877026

Start: 4626975

End: 4627718

Strand: Reverse

Name: plsC [H]

Synonym: Sbal195_3922

Alternate gene names: 160877026

Gene position: 4627718-4626975 (Counterclockwise)

Preceding gene: 160877027

Following gene: 160877025

Centisome position: 86.54

GC content: 46.24

Gene sequence:

>744_bases
GTGCTTTTAATCGTCAGATCAATGCTGTTGGCGGTGTCATTGTTGCTTGCCTTTATTTTTGGTGGCTTAGTGTGTTTATT
AAGACCTCGGCACCGCGACAATGTACATATGTTCGCCAAGATCTTCTCATCGGTCGCTCCGATCCTTGGGATCAAAGTGA
TTGTACGTCGACATAAAGATGTGCAGGATGGCCCCTATATTTTCCTCGCAAATCATCAGAATAACTTCGATCTTTTCACT
CACACGACAGCGGTACCTAAAGGCACTGTGAGTTTGGGCAAGAAGAGTTTGGCGTGGATGCCGTTATTCGGTCAAATTTA
TTGGTTGTCAGGGAATATTCTGATCGACCGCAAAAACCGTCATAGTGCCTTTGATACTATGGCGAAAACCGTGGAAAAAA
TTAAACAGAAGAATTTATCTGTGTGGATTTTCCCTGAAGGGACACGTTCACGTGGTCGCGGTTTGTTACCTTTTAAAGCG
GGCGCTTTCCATACTGCGATTGCGGCGGGAGTGCCTGTTGTGCCGGTATTGGCCTCGTGCCAAAGCCACATTAAGCTCAA
TCGCTGGAATAACGGTGTAGTCATTATCGATATGATGGCACCCGTGGCGACAGCAGGCTTAGATAAAGCCGATGTGAAAA
ACTTTTCTGCGCAAATCCATGCCAGTATGTCGGCGAGATTTGCTGAGATAAATCAAGAGGCGGCAGCACTTATGGGTAAA
ACTCTCGCGAGTGATGACGTATAA

Upstream 100 bases:

>100_bases
TGCTTGCTTGTTAGCAAGTCAGCTTACAGATGTAAACAATATATTGAGTCCCAAAGCCATGGTGGATATACTGTCGCCAC
TTTTATAGTCGGAGTAAATC

Downstream 100 bases:

>100_bases
TGCCAATTTGAGCCAGATTTACCTTAACGGAGACAAATCCATGTCTATTGAAAGTCAGTTAAAAGCCCAACTTGCAGAGA
ATCGTGACATAGTGCAAGCC

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MLLIVRSMLLAVSLLLAFIFGGLVCLLRPRHRDNVHMFAKIFSSVAPILGIKVIVRRHKDVQDGPYIFLANHQNNFDLFT
HTTAVPKGTVSLGKKSLAWMPLFGQIYWLSGNILIDRKNRHSAFDTMAKTVEKIKQKNLSVWIFPEGTRSRGRGLLPFKA
GAFHTAIAAGVPVVPVLASCQSHIKLNRWNNGVVIIDMMAPVATAGLDKADVKNFSAQIHASMSARFAEINQEAAALMGK
TLASDDV

Sequences:

>Translated_247_residues
MLLIVRSMLLAVSLLLAFIFGGLVCLLRPRHRDNVHMFAKIFSSVAPILGIKVIVRRHKDVQDGPYIFLANHQNNFDLFT
HTTAVPKGTVSLGKKSLAWMPLFGQIYWLSGNILIDRKNRHSAFDTMAKTVEKIKQKNLSVWIFPEGTRSRGRGLLPFKA
GAFHTAIAAGVPVVPVLASCQSHIKLNRWNNGVVIIDMMAPVATAGLDKADVKNFSAQIHASMSARFAEINQEAAALMGK
TLASDDV
>Mature_247_residues
MLLIVRSMLLAVSLLLAFIFGGLVCLLRPRHRDNVHMFAKIFSSVAPILGIKVIVRRHKDVQDGPYIFLANHQNNFDLFT
HTTAVPKGTVSLGKKSLAWMPLFGQIYWLSGNILIDRKNRHSAFDTMAKTVEKIKQKNLSVWIFPEGTRSRGRGLLPFKA
GAFHTAIAAGVPVVPVLASCQSHIKLNRWNNGVVIIDMMAPVATAGLDKADVKNFSAQIHASMSARFAEINQEAAALMGK
TLASDDV

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=215, Percent_Identity=33.4883720930233, Blast_Score=134, Evalue=9e-32,
Organism=Homo sapiens, GI15100175, Length=215, Percent_Identity=33.4883720930233, Blast_Score=134, Evalue=9e-32,
Organism=Homo sapiens, GI6041665, Length=242, Percent_Identity=33.0578512396694, Blast_Score=126, Evalue=2e-29,
Organism=Escherichia coli, GI1789395, Length=237, Percent_Identity=46.8354430379747, Blast_Score=238, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17564032, Length=190, Percent_Identity=34.7368421052632, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17568319, Length=238, Percent_Identity=31.9327731092437, Blast_Score=120, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6320151, Length=243, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=5e-34,
Organism=Drosophila melanogaster, GI281364648, Length=224, Percent_Identity=29.9107142857143, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24582856, Length=224, Percent_Identity=29.9107142857143, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24582854, Length=224, Percent_Identity=29.9107142857143, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24641614, Length=216, Percent_Identity=31.9444444444444, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24641612, Length=216, Percent_Identity=31.9444444444444, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27169; Mature: 27169

Theoretical pI: Translated: 10.90; Mature: 10.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLIVRSMLLAVSLLLAFIFGGLVCLLRPRHRDNVHMFAKIFSSVAPILGIKVIVRRHKD
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
VQDGPYIFLANHQNNFDLFTHTTAVPKGTVSLGKKSLAWMPLFGQIYWLSGNILIDRKNR
CCCCCEEEEECCCCCCEEEEEECCCCCCHHHHCCHHEEEEECCCEEEEEECCEEEECCCC
HSAFDTMAKTVEKIKQKNLSVWIFPEGTRSRGRGLLPFKAGAFHTAIAAGVPVVPVLASC
CHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHH
QSHIKLNRWNNGVVIIDMMAPVATAGLDKADVKNFSAQIHASMSARFAEINQEAAALMGK
HHCEEEEECCCCEEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLASDDV
HHCCCCC
>Mature Secondary Structure
MLLIVRSMLLAVSLLLAFIFGGLVCLLRPRHRDNVHMFAKIFSSVAPILGIKVIVRRHKD
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
VQDGPYIFLANHQNNFDLFTHTTAVPKGTVSLGKKSLAWMPLFGQIYWLSGNILIDRKNR
CCCCCEEEEECCCCCCEEEEEECCCCCCHHHHCCHHEEEEECCCEEEEEECCEEEECCCC
HSAFDTMAKTVEKIKQKNLSVWIFPEGTRSRGRGLLPFKAGAFHTAIAAGVPVVPVLASC
CHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHH
QSHIKLNRWNNGVVIIDMMAPVATAGLDKADVKNFSAQIHASMSARFAEINQEAAALMGK
HHCEEEEECCCCEEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLASDDV
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1557036; 9278503 [H]