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The map label for this gene is adrA [H]

Identifier: 160877024

GI number: 160877024

Start: 4625454

End: 4626440

Strand: Direct

Name: adrA [H]

Synonym: Sbal195_3920

Alternate gene names: 160877024

Gene position: 4625454-4626440 (Clockwise)

Preceding gene: 160877023

Following gene: 160877031

Centisome position: 86.5

GC content: 47.32

Gene sequence:

>987_bases
ATGTCAAATGACCAAAGCGCAATGAACGAACTACACTGGCTCATCGATATGGTGCAAACCATAGAGGTGGGATTAGTGGT
ATTAGATCGCCATTACAATATCCAGCTGTGGAACGGTTTTATGGAGAATCACAGCGGTGTTTCCCCTAATTCGATCAAAG
GTCAAAACCTGTTTACCCGCTTCCCCGATCTGCCCGTCACTTGGTTAAAGCAGAAAATGGAATCGGTTTTTATGCTTAAA
AACCGTGCCTTTATCAGCTGGGAACAACGTCCATACGTTTTCCAATTTAAAAACTACCGCCCGATCACGGGCCGTGCTGA
CTACATGTACCAAAACGTGACCTTGTTGCCACTGGCATCGCTCACGGGACAAGTGACCCATATCAGCGTGATTATTTATG
ACGTGACTGATATCGCCATCAACAAGTTACAACTTAAAGCCGCGAACGAGCAACTCGAGCGCCTAAGCCAAACCGATGGC
CTGACTCAGCTGCATAACCGTCGCCATTGGCAAGAATGTTTAGACCATGAGTACGACATATATGCCCGCTACTCAGGCAT
GGCAAGTTTAGTGATGATAGATATAGATAACTTTAAACATATCAACGACAGCTATGGTCATGTGGCGGGTGATAAAGTGA
TCCAGCATATCGCCCACTTACTCAGCCAATCCCTGCGTGAGACCGATTGCGCCGGACGTTATGGCGGCGAAGAATTTGCA
GTCGTATTGCCCAAAACTAGCGGCGCCGATGCCATGTATTTCACCGAGCGACTCAGGGAAAAAATCGCCGCATCCGTCAT
TCTGTATGAAAGCCTGAAGATCTCTGTGACTGTGAGTTTAGGTGTGTGCGAAATTGGTTCCCACATCACCAGCAGCTCAA
GCTGGATTTCTTGCTCCGATAAAGCGCTGTACGAAGCAAAGCAAAAAGGCCGTAATTGCAGCGTTTTGCATACCAGTACC
AGTGTGAACAAAACGACCCAAGACTAA

Upstream 100 bases:

>100_bases
TATTCAATGCGATTTGTTACTGCTCTTCACCGAGGATTCTATCCCCACGCTTAGCTATAAACTCGGCTATTTACTCGATT
AACCAGTTGGATTTTATCCT

Downstream 100 bases:

>100_bases
CATATCCACCCAATAAAAATGCCCATCATAGATGGGCATTTTTATTTAAAACGGGAACAAATTAGATATTCACGTGCGAA
TTAATGAGGGAAACCATCAT

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSNDQSAMNELHWLIDMVQTIEVGLVVLDRHYNIQLWNGFMENHSGVSPNSIKGQNLFTRFPDLPVTWLKQKMESVFMLK
NRAFISWEQRPYVFQFKNYRPITGRADYMYQNVTLLPLASLTGQVTHISVIIYDVTDIAINKLQLKAANEQLERLSQTDG
LTQLHNRRHWQECLDHEYDIYARYSGMASLVMIDIDNFKHINDSYGHVAGDKVIQHIAHLLSQSLRETDCAGRYGGEEFA
VVLPKTSGADAMYFTERLREKIAASVILYESLKISVTVSLGVCEIGSHITSSSSWISCSDKALYEAKQKGRNCSVLHTST
SVNKTTQD

Sequences:

>Translated_328_residues
MSNDQSAMNELHWLIDMVQTIEVGLVVLDRHYNIQLWNGFMENHSGVSPNSIKGQNLFTRFPDLPVTWLKQKMESVFMLK
NRAFISWEQRPYVFQFKNYRPITGRADYMYQNVTLLPLASLTGQVTHISVIIYDVTDIAINKLQLKAANEQLERLSQTDG
LTQLHNRRHWQECLDHEYDIYARYSGMASLVMIDIDNFKHINDSYGHVAGDKVIQHIAHLLSQSLRETDCAGRYGGEEFA
VVLPKTSGADAMYFTERLREKIAASVILYESLKISVTVSLGVCEIGSHITSSSSWISCSDKALYEAKQKGRNCSVLHTST
SVNKTTQD
>Mature_327_residues
SNDQSAMNELHWLIDMVQTIEVGLVVLDRHYNIQLWNGFMENHSGVSPNSIKGQNLFTRFPDLPVTWLKQKMESVFMLKN
RAFISWEQRPYVFQFKNYRPITGRADYMYQNVTLLPLASLTGQVTHISVIIYDVTDIAINKLQLKAANEQLERLSQTDGL
TQLHNRRHWQECLDHEYDIYARYSGMASLVMIDIDNFKHINDSYGHVAGDKVIQHIAHLLSQSLRETDCAGRYGGEEFAV
VLPKTSGADAMYFTERLREKIAASVILYESLKISVTVSLGVCEIGSHITSSSSWISCSDKALYEAKQKGRNCSVLHTSTS
VNKTTQD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=169, Percent_Identity=36.094674556213, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082007, Length=166, Percent_Identity=39.7590361445783, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787541, Length=290, Percent_Identity=26.551724137931, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87081881, Length=182, Percent_Identity=35.7142857142857, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI145693134, Length=155, Percent_Identity=32.258064516129, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787262, Length=206, Percent_Identity=29.126213592233, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788381, Length=199, Percent_Identity=29.6482412060301, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI87081977, Length=177, Percent_Identity=32.7683615819209, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787802, Length=189, Percent_Identity=29.6296296296296, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1787816, Length=177, Percent_Identity=31.0734463276836, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1788085, Length=193, Percent_Identity=29.0155440414508, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788956, Length=169, Percent_Identity=30.1775147928994, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87081974, Length=159, Percent_Identity=27.0440251572327, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 37333; Mature: 37202

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDQSAMNELHWLIDMVQTIEVGLVVLDRHYNIQLWNGFMENHSGVSPNSIKGQNLFTR
CCCHHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEEECHHHCCCCCCCCCCCCCCHHHC
FPDLPVTWLKQKMESVFMLKNRAFISWEQRPYVFQFKNYRPITGRADYMYQNVTLLPLAS
CCCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCHHEECCEEEEEHHH
LTGQVTHISVIIYDVTDIAINKLQLKAANEQLERLSQTDGLTQLHNRRHWQECLDHEYDI
HCCCEEEEEEEEEEHHHHHHHHEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEE
YARYSGMASLVMIDIDNFKHINDSYGHVAGDKVIQHIAHLLSQSLRETDCAGRYGGEEFA
EEEECCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VVLPKTSGADAMYFTERLREKIAASVILYESLKISVTVSLGVCEIGSHITSSSSWISCSD
EEEECCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECHHHHCCCCCCCCCEEECCH
KALYEAKQKGRNCSVLHTSTSVNKTTQD
HHHHHHHHCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SNDQSAMNELHWLIDMVQTIEVGLVVLDRHYNIQLWNGFMENHSGVSPNSIKGQNLFTR
CCHHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEEECHHHCCCCCCCCCCCCCCHHHC
FPDLPVTWLKQKMESVFMLKNRAFISWEQRPYVFQFKNYRPITGRADYMYQNVTLLPLAS
CCCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCHHEECCEEEEEHHH
LTGQVTHISVIIYDVTDIAINKLQLKAANEQLERLSQTDGLTQLHNRRHWQECLDHEYDI
HCCCEEEEEEEEEEHHHHHHHHEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEE
YARYSGMASLVMIDIDNFKHINDSYGHVAGDKVIQHIAHLLSQSLRETDCAGRYGGEEFA
EEEECCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VVLPKTSGADAMYFTERLREKIAASVILYESLKISVTVSLGVCEIGSHITSSSSWISCSD
EEEECCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECHHHHCCCCCCCCCEEECCH
KALYEAKQKGRNCSVLHTSTSVNKTTQD
HHHHHHHHCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]