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The map label for this gene is aer [H]

Identifier: 160877012

GI number: 160877012

Start: 4605216

End: 4606790

Strand: Reverse

Name: aer [H]

Synonym: Sbal195_3908

Alternate gene names: 160877012

Gene position: 4606790-4605216 (Counterclockwise)

Preceding gene: 160877014

Following gene: 160877010

Centisome position: 86.15

GC content: 48.76

Gene sequence:

>1575_bases
ATGAGAACTAATCTACCAGTTACACAGCGAGAATATGATTATCCAGCGGATTGGATTTTATTGTCGACCACGGATACTCA
AAGTCATATTACCTACGCCAACCAATCCTTTTGTACCGTTGCCGGTTTTGAACTTGATGCCATGTTAGGCAAGCCCCACA
ACATGGTGCGTCATCCAGATATGCCTCCCCATGCGTTTGAAGATATGTGGCGCTGCATCAAAAAAGGCGAGCCTTGGAAA
GGGATAGTGAAAAATCGCTGTGCCAATGGCGATCACTATTGGGTTGATGCCTATGTCTCACCCATCTCAGTTAATGGTAA
AGTCGTCGAGTTTCAATCTGTACGCACTAAACCCACCCGCGAGCAGGTTAAGCGTGCAGAAACGGCTTATGCAGAGTTGA
ACAAAAAGGGCAGTGTCAGCGCGTTAAAACGTACAGTGAGCATGCCCGCCAAATTGCTATTACTAGCCCTACTTGCCATG
CTGCCGATGCTTTACCTTGCTCTGCAAATTGGCTTAATGGGCTTTATTGCCCTAGCGATAAGCATCTTAGTGTTGCTGGT
GGGCGGTAATCTGGTGCTGAGTCGTTATTACGCGATAGTGGCTAAGGCAAAGCATATCTACGATAACCCCTTGATGGCGC
ATATTTACAGTGGAAGCTCTGATGATCTTGGCGCGATTGATCTGGCGCTCCAAATGCAGACCTCTGAGCTTAAGTCGATT
CTGGGGCGTGCATCGGATTCCTGTTATAACGTGTCTGAACAGGCCAAAATATCTGCCGCCAAGGGTAAACAAATCCAGAG
TACCAGTCAGGCTCAATTGTCTGAAATAGAGCAAGTTGCTACGGCGATGCAGGAGATGACCGCCACATTAGGCGATATGT
CTTCCAATTGTGCCGATGCCGCCAGTGCCACGCAAATGGCATCCGCTGAAACCATCAATGGCGATAAAACGGTGTCGAGC
ACCATTAGCTCGATTCAAGCTATGGCGGAGCAACTGCAACAAACGTCGAAGGTTATTACTGAGTTAGAAGCCCACAGTAA
AGATATCGGCACTGTGCTAGATGTGATTCAGAGTATTGCGGGTCAGACTAATCTACTGGCATTAAATGCCGCGATTGAAG
CGGCGCGTGCAGGTGAGCAAGGCCGTGGCTTTGCCGTTGTTGCTGACGAGGTTAGGGCATTGGCGCAACGTACCCACGAT
GCCACCAAGGAAATCCAAAGCATGATTAACCTGTTGCAGCAGGGGACTAATAAAGCTGTGGTCAGCATGCAGCAAGGTGT
GGTTGCCGCTTCCCAATGTATTTCAACGGCGGATTTAGCAGGCACGGCATTACGTACGATTCGTGAGGCCATTTCGACCA
TTACCGATATGACGCACCATATTGCTAGTGCGGTTGAAGAGCAATCGAGCGTGGCGAATGAGATGAATCGCAGCGTGGTG
AATGTGTCGCAATTTACCCATTCCAGCCATCAACTTGGCAGTGAAATGGTCGGCTTGAACGATGAAGTGACTCGCGAGAT
GGATTCTCACTCGGTATTGGTCGATCAATTCTTAAAGCGCAGCTTTAGGGTTTAA

Upstream 100 bases:

>100_bases
AGAAGTAGGTTCAGGAATATAGAGTCAGGGTGATGATGCCTCACGGATGGATAACTCATGGATGAATAACGAAGAATTAA
TCAAAGATCCATAAGGTTTC

Downstream 100 bases:

>100_bases
TCACCTAAAACTTAAGATAAAAAGGCAATAGTCTGACTATTGCCTTTGCTTTTTCTGCTCCCTGACTCAATTTCATTTTT
CTAACTTAATTTCTGCTCTC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MRTNLPVTQREYDYPADWILLSTTDTQSHITYANQSFCTVAGFELDAMLGKPHNMVRHPDMPPHAFEDMWRCIKKGEPWK
GIVKNRCANGDHYWVDAYVSPISVNGKVVEFQSVRTKPTREQVKRAETAYAELNKKGSVSALKRTVSMPAKLLLLALLAM
LPMLYLALQIGLMGFIALAISILVLLVGGNLVLSRYYAIVAKAKHIYDNPLMAHIYSGSSDDLGAIDLALQMQTSELKSI
LGRASDSCYNVSEQAKISAAKGKQIQSTSQAQLSEIEQVATAMQEMTATLGDMSSNCADAASATQMASAETINGDKTVSS
TISSIQAMAEQLQQTSKVITELEAHSKDIGTVLDVIQSIAGQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHD
ATKEIQSMINLLQQGTNKAVVSMQQGVVAASQCISTADLAGTALRTIREAISTITDMTHHIASAVEEQSSVANEMNRSVV
NVSQFTHSSHQLGSEMVGLNDEVTREMDSHSVLVDQFLKRSFRV

Sequences:

>Translated_524_residues
MRTNLPVTQREYDYPADWILLSTTDTQSHITYANQSFCTVAGFELDAMLGKPHNMVRHPDMPPHAFEDMWRCIKKGEPWK
GIVKNRCANGDHYWVDAYVSPISVNGKVVEFQSVRTKPTREQVKRAETAYAELNKKGSVSALKRTVSMPAKLLLLALLAM
LPMLYLALQIGLMGFIALAISILVLLVGGNLVLSRYYAIVAKAKHIYDNPLMAHIYSGSSDDLGAIDLALQMQTSELKSI
LGRASDSCYNVSEQAKISAAKGKQIQSTSQAQLSEIEQVATAMQEMTATLGDMSSNCADAASATQMASAETINGDKTVSS
TISSIQAMAEQLQQTSKVITELEAHSKDIGTVLDVIQSIAGQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHD
ATKEIQSMINLLQQGTNKAVVSMQQGVVAASQCISTADLAGTALRTIREAISTITDMTHHIASAVEEQSSVANEMNRSVV
NVSQFTHSSHQLGSEMVGLNDEVTREMDSHSVLVDQFLKRSFRV
>Mature_524_residues
MRTNLPVTQREYDYPADWILLSTTDTQSHITYANQSFCTVAGFELDAMLGKPHNMVRHPDMPPHAFEDMWRCIKKGEPWK
GIVKNRCANGDHYWVDAYVSPISVNGKVVEFQSVRTKPTREQVKRAETAYAELNKKGSVSALKRTVSMPAKLLLLALLAM
LPMLYLALQIGLMGFIALAISILVLLVGGNLVLSRYYAIVAKAKHIYDNPLMAHIYSGSSDDLGAIDLALQMQTSELKSI
LGRASDSCYNVSEQAKISAAKGKQIQSTSQAQLSEIEQVATAMQEMTATLGDMSSNCADAASATQMASAETINGDKTVSS
TISSIQAMAEQLQQTSKVITELEAHSKDIGTVLDVIQSIAGQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHD
ATKEIQSMINLLQQGTNKAVVSMQQGVVAASQCISTADLAGTALRTIREAISTITDMTHHIASAVEEQSSVANEMNRSVV
NVSQFTHSSHQLGSEMVGLNDEVTREMDSHSVLVDQFLKRSFRV

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=509, Percent_Identity=32.0235756385069, Blast_Score=232, Evalue=6e-62,
Organism=Escherichia coli, GI1787690, Length=324, Percent_Identity=29.320987654321, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI2367378, Length=385, Percent_Identity=26.7532467532467, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788195, Length=234, Percent_Identity=35.4700854700855, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1788194, Length=261, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 56869; Mature: 56869

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTNLPVTQREYDYPADWILLSTTDTQSHITYANQSFCTVAGFELDAMLGKPHNMVRHPD
CCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCEEEEECCCHHHHHCCCCCCCCCCC
MPPHAFEDMWRCIKKGEPWKGIVKNRCANGDHYWVDAYVSPISVNGKVVEFQSVRTKPTR
CCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECEEECCCEEEEECCCCCCCHH
EQVKRAETAYAELNKKGSVSALKRTVSMPAKLLLLALLAMLPMLYLALQIGLMGFIALAI
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILVLLVGGNLVLSRYYAIVAKAKHIYDNPLMAHIYSGSSDDLGAIDLALQMQTSELKSI
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
LGRASDSCYNVSEQAKISAAKGKQIQSTSQAQLSEIEQVATAMQEMTATLGDMSSNCADA
HHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ASATQMASAETINGDKTVSSTISSIQAMAEQLQQTSKVITELEAHSKDIGTVLDVIQSIA
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHDATKEIQSMINLLQQGTNKAV
CCCCEEEHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VSMQQGVVAASQCISTADLAGTALRTIREAISTITDMTHHIASAVEEQSSVANEMNRSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVSQFTHSSHQLGSEMVGLNDEVTREMDSHSVLVDQFLKRSFRV
HHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRTNLPVTQREYDYPADWILLSTTDTQSHITYANQSFCTVAGFELDAMLGKPHNMVRHPD
CCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCEEEEECCCHHHHHCCCCCCCCCCC
MPPHAFEDMWRCIKKGEPWKGIVKNRCANGDHYWVDAYVSPISVNGKVVEFQSVRTKPTR
CCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECEEECCCEEEEECCCCCCCHH
EQVKRAETAYAELNKKGSVSALKRTVSMPAKLLLLALLAMLPMLYLALQIGLMGFIALAI
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILVLLVGGNLVLSRYYAIVAKAKHIYDNPLMAHIYSGSSDDLGAIDLALQMQTSELKSI
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
LGRASDSCYNVSEQAKISAAKGKQIQSTSQAQLSEIEQVATAMQEMTATLGDMSSNCADA
HHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ASATQMASAETINGDKTVSSTISSIQAMAEQLQQTSKVITELEAHSKDIGTVLDVIQSIA
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHDATKEIQSMINLLQQGTNKAV
CCCCEEEHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VSMQQGVVAASQCISTADLAGTALRTIREAISTITDMTHHIASAVEEQSSVANEMNRSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVSQFTHSSHQLGSEMVGLNDEVTREMDSHSVLVDQFLKRSFRV
HHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]