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The map label for this gene is ubiH [H]

Identifier: 160876907

GI number: 160876907

Start: 4484290

End: 4485516

Strand: Reverse

Name: ubiH [H]

Synonym: Sbal195_3803

Alternate gene names: 160876907

Gene position: 4485516-4484290 (Counterclockwise)

Preceding gene: 160876908

Following gene: 160876906

Centisome position: 83.88

GC content: 52.65

Gene sequence:

>1227_bases
ATGACGGCCACAAATCACATGGATACTTCAGTTCAACATGTCGACATCGCGATTGTAGGCGGTGCGATGGCGGGGGCGAC
TCTCGCGTTGGCTCTCGCGCGTCTGTCTTTATCCGCAGCTAGGCCGCTTTCCATCGCCTTAATCGAGGCGCACCTTCCCG
ATAAACAACACCCCGGATTCGATGCTCGCTCCATCGCTATCGCCCACGGCTCAATTTTCGAATTGTCCCGTTTAGGTCTA
TGGCCAAAGCTCGCCCATTTGGGCACGGCGATTGAAAATATCCATGTATCGGATCGCGGCCACTTTGGCATGACAGAGCT
CAATGCCGCTCAGTTTCATTTAGATGCCTTAGGCCAAGTTGTTGAGCTTGAGCGTGTCGGCCAAGTGTTGTTTAACGAGT
TGAATAAGAGCGAGGTAAAACTCTATTGCCCCGCCAAGCTTGCCCAAGTGGAACCCGCCGTTGAAGGCCACACCTTAGTG
CTCGACACGGGCGAGCGCCTTAAAGCCAAACTCGTGGTCGCCGCCGATGGTCTGCAATCCAAAGTGCGCAGCAGTTTTGC
TTTGCCCGTGACCCAAGTGGCTTTTGAGCAAACTGCGATTATTGCCAATATTCAAACCGACAAGCCGCATCAACATTTGG
CCTATGAGCGTTTTACCCAAACGGGTCCTTTAGCGTTATTGCCTATGGCCGATAGCCAAGGTCAACCTCGCTTATCACTG
GTGTGGGCGCTCGATGATGCACGGGCTAAACAGATGCAAACCGCGCCTAAAGCGGAATTTTTAGCGGCGCTGCAGCAGGC
CTTTGGTTATCGAGCAGGCACGTTTATCGATGTCAGCGCGCGTCATGCGTATCCGCTTAATTTGTCGTATATGCCAAGGC
CAATCCATCACAGATGTGTGTTTATCGGTAATGCCGCGCAGACGCTGCATCCAATTGCGGGGCAAGGATTTAACTTAGGC
CTGCGGGATGTAGTGAGCTTGCTTGATGTGCTCAAAACGGCGCTAGATCAGGGTGATGATATCGGCTCCGCCGCCGTGAC
CCATGCTTATCTTAATGCCCGCGAGCACGACAGAAACAGCACTATCCGCAACATCGAATTTTTAGTCCGTGGCTTTTCAA
ACCAATACTGGCCGATGGCGCTGGGTCGTAACTTAGGCTTGCGCTTATTATCTTGGTTTCCGCCACTTAAAACCCCCGTT
GCTCAAAAGGCGATGGGCTGGAAATAA

Upstream 100 bases:

>100_bases
TGAATCCATAGCACTGGTGTTTTTGAGTGCATAGCACTGATGTTTACATCTCTTATGTTTACATGCTTTAGTGCCATGCC
AAAGCTTGAATGAGATCCCC

Downstream 100 bases:

>100_bases
CCCGCTTTTCATTACTGGTATCGCAACGCGAAAAGGATGTACCCATGTTAAGTTCACAAGCCTATGACATCGCCATTGTG
GGTGGCGGCATGGTGGGACT

Product: 2-polyprenyl-6-methoxyphenol 4-hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MTATNHMDTSVQHVDIAIVGGAMAGATLALALARLSLSAARPLSIALIEAHLPDKQHPGFDARSIAIAHGSIFELSRLGL
WPKLAHLGTAIENIHVSDRGHFGMTELNAAQFHLDALGQVVELERVGQVLFNELNKSEVKLYCPAKLAQVEPAVEGHTLV
LDTGERLKAKLVVAADGLQSKVRSSFALPVTQVAFEQTAIIANIQTDKPHQHLAYERFTQTGPLALLPMADSQGQPRLSL
VWALDDARAKQMQTAPKAEFLAALQQAFGYRAGTFIDVSARHAYPLNLSYMPRPIHHRCVFIGNAAQTLHPIAGQGFNLG
LRDVVSLLDVLKTALDQGDDIGSAAVTHAYLNAREHDRNSTIRNIEFLVRGFSNQYWPMALGRNLGLRLLSWFPPLKTPV
AQKAMGWK

Sequences:

>Translated_408_residues
MTATNHMDTSVQHVDIAIVGGAMAGATLALALARLSLSAARPLSIALIEAHLPDKQHPGFDARSIAIAHGSIFELSRLGL
WPKLAHLGTAIENIHVSDRGHFGMTELNAAQFHLDALGQVVELERVGQVLFNELNKSEVKLYCPAKLAQVEPAVEGHTLV
LDTGERLKAKLVVAADGLQSKVRSSFALPVTQVAFEQTAIIANIQTDKPHQHLAYERFTQTGPLALLPMADSQGQPRLSL
VWALDDARAKQMQTAPKAEFLAALQQAFGYRAGTFIDVSARHAYPLNLSYMPRPIHHRCVFIGNAAQTLHPIAGQGFNLG
LRDVVSLLDVLKTALDQGDDIGSAAVTHAYLNAREHDRNSTIRNIEFLVRGFSNQYWPMALGRNLGLRLLSWFPPLKTPV
AQKAMGWK
>Mature_407_residues
TATNHMDTSVQHVDIAIVGGAMAGATLALALARLSLSAARPLSIALIEAHLPDKQHPGFDARSIAIAHGSIFELSRLGLW
PKLAHLGTAIENIHVSDRGHFGMTELNAAQFHLDALGQVVELERVGQVLFNELNKSEVKLYCPAKLAQVEPAVEGHTLVL
DTGERLKAKLVVAADGLQSKVRSSFALPVTQVAFEQTAIIANIQTDKPHQHLAYERFTQTGPLALLPMADSQGQPRLSLV
WALDDARAKQMQTAPKAEFLAALQQAFGYRAGTFIDVSARHAYPLNLSYMPRPIHHRCVFIGNAAQTLHPIAGQGFNLGL
RDVVSLLDVLKTALDQGDDIGSAAVTHAYLNAREHDRNSTIRNIEFLVRGFSNQYWPMALGRNLGLRLLSWFPPLKTPVA
QKAMGWK

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=407, Percent_Identity=26.7813267813268, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI32967307, Length=335, Percent_Identity=27.7611940298507, Blast_Score=122, Evalue=7e-28,
Organism=Escherichia coli, GI1789274, Length=396, Percent_Identity=46.2121212121212, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1789273, Length=401, Percent_Identity=33.4164588528678, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1786883, Length=382, Percent_Identity=31.6753926701571, Blast_Score=153, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI25146631, Length=437, Percent_Identity=26.0869565217391, Blast_Score=138, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6321694, Length=451, Percent_Identity=22.8381374722838, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI19920760, Length=454, Percent_Identity=26.431718061674, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 44483; Mature: 44352

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATNHMDTSVQHVDIAIVGGAMAGATLALALARLSLSAARPLSIALIEAHLPDKQHPGF
CCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCC
DARSIAIAHGSIFELSRLGLWPKLAHLGTAIENIHVSDRGHFGMTELNAAQFHLDALGQV
CCCEEEEECCCHHHHHHHCCCHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHH
VELERVGQVLFNELNKSEVKLYCPAKLAQVEPAVEGHTLVLDTGERLKAKLVVAADGLQS
HHHHHHHHHHHHHCCCCCEEEECCHHHHHCCCCCCCCEEEEECCCCCEEEEEEEECCHHH
KVRSSFALPVTQVAFEQTAIIANIQTDKPHQHLAYERFTQTGPLALLPMADSQGQPRLSL
HHHHHCCCCHHHHHHHHEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCEEE
VWALDDARAKQMQTAPKAEFLAALQQAFGYRAGTFIDVSARHAYPLNLSYMPRPIHHRCV
EEEECHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEECCCCCCCCCCCCEEE
FIGNAAQTLHPIAGQGFNLGLRDVVSLLDVLKTALDQGDDIGSAAVTHAYLNAREHDRNS
EECCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHCCCCC
TIRNIEFLVRGFSNQYWPMALGRNLGLRLLSWFPPLKTPVAQKAMGWK
HHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
TATNHMDTSVQHVDIAIVGGAMAGATLALALARLSLSAARPLSIALIEAHLPDKQHPGF
CCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCC
DARSIAIAHGSIFELSRLGLWPKLAHLGTAIENIHVSDRGHFGMTELNAAQFHLDALGQV
CCCEEEEECCCHHHHHHHCCCHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHH
VELERVGQVLFNELNKSEVKLYCPAKLAQVEPAVEGHTLVLDTGERLKAKLVVAADGLQS
HHHHHHHHHHHHHCCCCCEEEECCHHHHHCCCCCCCCEEEEECCCCCEEEEEEEECCHHH
KVRSSFALPVTQVAFEQTAIIANIQTDKPHQHLAYERFTQTGPLALLPMADSQGQPRLSL
HHHHHCCCCHHHHHHHHEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCEEE
VWALDDARAKQMQTAPKAEFLAALQQAFGYRAGTFIDVSARHAYPLNLSYMPRPIHHRCV
EEEECHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEECCCCCCCCCCCCEEE
FIGNAAQTLHPIAGQGFNLGLRDVVSLLDVLKTALDQGDDIGSAAVTHAYLNAREHDRNS
EECCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHCCCCC
TIRNIEFLVRGFSNQYWPMALGRNLGLRLLSWFPPLKTPVAQKAMGWK
HHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]