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The map label for this gene is sdaC [H]

Identifier: 160876780

GI number: 160876780

Start: 4334031

End: 4335326

Strand: Reverse

Name: sdaC [H]

Synonym: Sbal195_3674

Alternate gene names: 160876780

Gene position: 4335326-4334031 (Counterclockwise)

Preceding gene: 160876785

Following gene: 160876778

Centisome position: 81.08

GC content: 46.68

Gene sequence:

>1296_bases
ATGCAAAAAGATGCGACCAGTGTTCTTGGAACACCTCAAAGCACACAGAATCTAGATTCAACGAAACACTTACCTTGGAC
TCGCCAAGATACGACTTGGATGTTGAGTTTATTTGGCACAGCCGTTGGCGCTGGAATTTTATTTTTACCCATCAATGCGG
GCATGGGCGGCTTTTGGCCTCTCGTACTCATGGCAGTGATCATCGGTCCTATGACCTATCTTGCCCACCGCGGTTTATCT
CGTTTTGTTTGTTCATCAAGCATTCCCGGCAGCGACATCACCCAAGTAGTAGAAGAACATTTTGGTGTGGGTGCGGGTAA
AGCCATTACCATACTGTATTTCTTCGCCATCTATCCGATTGTATTAATTTACGGTGTGGGTATTACCAACACAGTCGATA
GCTTTATCGTCAATCAGTTGGGCATGGCATCGCCACCACGCTTTATTTTATCGGGTGTATTGATCCTTGGTATGATGGCT
GTGATGGTTGCGGGCGAGAAGTTCATGCTGAAAGTGACACAATTGCTGGTATATCCGCTGGTGGGTATTTTGGCCTTTAT
GTCGTTCTACCTGATCCCAGAATGGAAAATGGATGCCTTACAAGTTGTGCCAGAAGCGGGTGCATTTTTAGGTACAGTGT
GGTTGACGATCCCAGTTTTGGTGTTCGCCTTTAACCATTCTCCTGCGATTTCACAGTTTTCAGTGTCACTGAAACGTGAC
CACGGCGCCAATGCTTCTCGTAAAGCTGACGTGATTTTACGTAACACTTCGATGATGTTAGTGGGCTTTGTGATGTTGTT
TGTGTTCTCTTGTGTGCTGTCGTTGTCGCCAGCCCAATTGGCAGAAGCGAAAGCGCAGAACTTACCGATTCTGTCTTACT
TAGCCAACGTGCATTCAAGTGGTTTTGTGAGCTACTTTGGTCCGTTAATCGCCTTTATCGCGATTGTGTCCTCTTTCTTC
GGCCATTACATGGGCGCGACAGAAGGCATGAAAGGCGTGATCGTTAAGCAGTTACGCTCAAGCGGCAAATCAGTCGCTGA
CGCTAAGATCAACAAGTTCATCCTAGGCTTTATGTTTGTCACTATCTGGGCTGTGGCTGTGATCAACCCAAGTATCCTAG
GCATGATTGAAGCTTTAGGCGGCCCAATTATCGCGGCTATCCTGTACTTGATGCCTATGTATGCCGTGTATAAAGTGCCA
GCGTTAAAAGCCTATCGTGGCCGTATCAGCAATATCTTCGTGATCATTGCAGGTTTACTGGCGATGACGGCGATTCTGTT
TGGTTTCTTCCGTTAA

Upstream 100 bases:

>100_bases
TCCCTTACATAAAGCCGAGTCAGATCAACTTTTATGGGCTTTTTTTGGTTATCCTTACGACGAATTTATTATGCTAGTCA
CACCGTAAGGTAACTTTTAT

Downstream 100 bases:

>100_bases
GTTTTACGAGTGCAGTGAAGCTTAACGAGGAGTTAGCGTTAGGCTTTTAATCTGAATCGTGACTCGTAAAAAAAGGATCG
TGCCATTGGCCCGATCCTTT

Product: aromatic amino acid permease

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MQKDATSVLGTPQSTQNLDSTKHLPWTRQDTTWMLSLFGTAVGAGILFLPINAGMGGFWPLVLMAVIIGPMTYLAHRGLS
RFVCSSSIPGSDITQVVEEHFGVGAGKAITILYFFAIYPIVLIYGVGITNTVDSFIVNQLGMASPPRFILSGVLILGMMA
VMVAGEKFMLKVTQLLVYPLVGILAFMSFYLIPEWKMDALQVVPEAGAFLGTVWLTIPVLVFAFNHSPAISQFSVSLKRD
HGANASRKADVILRNTSMMLVGFVMLFVFSCVLSLSPAQLAEAKAQNLPILSYLANVHSSGFVSYFGPLIAFIAIVSSFF
GHYMGATEGMKGVIVKQLRSSGKSVADAKINKFILGFMFVTIWAVAVINPSILGMIEALGGPIIAAILYLMPMYAVYKVP
ALKAYRGRISNIFVIIAGLLAMTAILFGFFR

Sequences:

>Translated_431_residues
MQKDATSVLGTPQSTQNLDSTKHLPWTRQDTTWMLSLFGTAVGAGILFLPINAGMGGFWPLVLMAVIIGPMTYLAHRGLS
RFVCSSSIPGSDITQVVEEHFGVGAGKAITILYFFAIYPIVLIYGVGITNTVDSFIVNQLGMASPPRFILSGVLILGMMA
VMVAGEKFMLKVTQLLVYPLVGILAFMSFYLIPEWKMDALQVVPEAGAFLGTVWLTIPVLVFAFNHSPAISQFSVSLKRD
HGANASRKADVILRNTSMMLVGFVMLFVFSCVLSLSPAQLAEAKAQNLPILSYLANVHSSGFVSYFGPLIAFIAIVSSFF
GHYMGATEGMKGVIVKQLRSSGKSVADAKINKFILGFMFVTIWAVAVINPSILGMIEALGGPIIAAILYLMPMYAVYKVP
ALKAYRGRISNIFVIIAGLLAMTAILFGFFR
>Mature_431_residues
MQKDATSVLGTPQSTQNLDSTKHLPWTRQDTTWMLSLFGTAVGAGILFLPINAGMGGFWPLVLMAVIIGPMTYLAHRGLS
RFVCSSSIPGSDITQVVEEHFGVGAGKAITILYFFAIYPIVLIYGVGITNTVDSFIVNQLGMASPPRFILSGVLILGMMA
VMVAGEKFMLKVTQLLVYPLVGILAFMSFYLIPEWKMDALQVVPEAGAFLGTVWLTIPVLVFAFNHSPAISQFSVSLKRD
HGANASRKADVILRNTSMMLVGFVMLFVFSCVLSLSPAQLAEAKAQNLPILSYLANVHSSGFVSYFGPLIAFIAIVSSFF
GHYMGATEGMKGVIVKQLRSSGKSVADAKINKFILGFMFVTIWAVAVINPSILGMIEALGGPIIAAILYLMPMYAVYKVP
ALKAYRGRISNIFVIIAGLLAMTAILFGFFR

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=428, Percent_Identity=54.2056074766355, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1789504, Length=435, Percent_Identity=43.6781609195402, Blast_Score=343, Evalue=1e-95,
Organism=Escherichia coli, GI1789211, Length=408, Percent_Identity=35.0490196078431, Blast_Score=245, Evalue=4e-66,
Organism=Escherichia coli, GI1789961, Length=404, Percent_Identity=26.4851485148515, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI145693183, Length=429, Percent_Identity=25.1748251748252, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 46614; Mature: 46614

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]