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The map label for this gene is dcp [H]

Identifier: 160876101

GI number: 160876101

Start: 3555872

End: 3558022

Strand: Direct

Name: dcp [H]

Synonym: Sbal195_2992

Alternate gene names: 160876101

Gene position: 3555872-3558022 (Clockwise)

Preceding gene: 160876100

Following gene: 160876105

Centisome position: 66.5

GC content: 50.4

Gene sequence:

>2151_bases
ATGCGTAAACGTTTTATTGCCATCGCCATCGGCGCCACGCTCACCGCCGGATTTATGGCAGGTTGTAGCAACACAGAAAG
CAAAGCCCCTAACGCCATGTCGGTACAAGCCCAAAACCCCTTGTTTCAAGTCAGTAGTCTGCAATATCAAGCGCCCGACT
TTAGCCTCATCAAGAATGAGCATTTTACGCCTGCCCTAGAGCAAGGTATGGCCGAGCACTATCAAGAAATCCTCGCGATT
GCGAATAATCCCGCAGCGGCCAGTTTTGATAACACCATTGTGGCTATGGAAAAAAGCGGTGCCCTGCTCAGCCGCGCATC
GAGTGTGTTTTATAATCTAGCGGGTTCGAACAGCAATCCAGTGCTGCGTAAAATTCAAGGTGAAATGGCACCCAAAATGG
CGGCGCACTCGGACAACATTAACTTAAATCCAGCGCTATTTGCCCGTATCGAAGCCATTTATAACGATCGTACTAATCTA
GGTTTAACCCCAGAAGCCGTGCGTTTGGTTGAGGTCTATCATCAACGCTTTATCATGGCGGGCGCTAAGCTGACTGATGA
GCAGAAAGTGAAGATCCGCGCATTAAATGAAGAACAATCGACACTGACCAATGAGTTTTCCCAGCGTTTACTGCGCTTAA
CTAAAGAAATCGCCGTGGTCGTGGAGTCAAAGAATGAACTTGCAGGATTAACTGACAGCGACATCACTTCAGCCGCAAAC
GATGCTAAAGCGGCGGGTCACGATGGCAAGTATCTGATCAACATCACCAACACCACTCGTCAGCCCGTATTGGCGTCACT
GGAAAACCGTGAACTGCGCCAACGCATTTGGGAAGCCTCTGCTAACCGTGGCTTAACGGGTGAAAACGAAACCGCATCTT
TAGTGTCTCGTTTAGCGCAATTACGTGCCGAGCGTGCCGCGCTATTAGGTTATGAAAACTGGGCCAGTTATCGCCTAGCG
CCGCAAATGGCCAAAACACCAGAAGCGGTTTACAGCATGTTTGGCTCTATGGTGCCAGCCGTAGTCGCAAATACAGAGAA
AGAAGCGGCCGATATTCAAGCCATGATCGACAAGACTGGCGGCAAATTTGAACTGGCGCCATGGGACTGGGAATTCTACG
CCGAGAAAGTCCGCCAAGAAAAATACGCCCTCGATGGTAATAGCATTCGCCCATACTTTGAGTTTAACCGCGTCCTCGAA
GATGGCGTGTTCTACACACTCAAAGAACTCTATGGCGTCACCCTAAAACCTCGCCCAGATTTACCGGTTTATCATCCCGA
TGTGAAAGCCTACGAAATGTTTGATGCCGATGGCTCAAGCATGGCCATTTTCTACGCCGACTATTTTGCCCGTGAAGGTA
AACGTGGCGGCGCTTGGATGAGTTCGTTCGTCGGTCAATCCTTCCTCGAAGGCACTAAACCTGTGGTCGTCAACGTGATG
AACATCAAGAAAGCGCCAGAGGGTGAACCCACATTCGTCAGCTATAACGAAGTCACCACCATGTTCCATGAAATGGGCCA
CGGCACCCACGGCATGTTCTCTAAAGTGACTTACCCTAGTCTGGCGGGCACTTCGGTTTCCCGCGACTTTGTCGAATTCC
CATCAACCTTCGAAGAAGACTGGGCGGCCCATCCCAAAGTGTTGGCCAACTACGCGAAACACTATGAAACCGGCAAACCG
ATTCCCGACGAATTGCTGCAAAAACTGCTGAAATCTGGCAGCTTTAACCAAGGGTTCGACACACTGGAATACATGGCCGC
CGCATTAGTGGATATGGAGTGGCATTCATTAAGCCCAGATGCACCACTGCAAGATGTGGCCACCTTTGAAGCCAATGCCC
TGAAAAAGCACGGCTTAAACATCAGCGCCGTGCCCCCACGCTATAAATCGACCTACTTTGCCCACGCCTTCCCCGGTGGT
TACTCGGCAAGTTATTACGCGTATATGTGGAGTGAGATTTTAGCGGCGGATGCCTTTGCCTATGTGCAAACCCAAGGCGG
GCTCAATCGTGAAATCGGCATGAAATACCGCAAAACCATTCGTGAAGTGGGCAATAGCATAGCGCCAATGGAAGCCTACA
AAAACTTCCGCGGACAAGAGCCAACGACACAAGGATTACTTAAACGCCGCGGGCTAGACCAAGCACTCTAA

Upstream 100 bases:

>100_bases
TTATTTAGATACAGCCCCATAACAAGCCATTTTCAGTCCCATTTAAGTTACTAACGTTACAGTCCTAAAAAAACAACAAT
TCAAAGGAAGTCACTCAATT

Downstream 100 bases:

>100_bases
GCTACAAAAATCCTAAGCGGCAAGTAGCCTAAGTTAAGTACTGATAGCCTTAATGTGATTAGGTTAAAGATAGAGATAGA
GCGTTAACCAAAAAAATCAG

Product: peptidyl-dipeptidase Dcp

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 716; Mature: 716

Protein sequence:

>716_residues
MRKRFIAIAIGATLTAGFMAGCSNTESKAPNAMSVQAQNPLFQVSSLQYQAPDFSLIKNEHFTPALEQGMAEHYQEILAI
ANNPAAASFDNTIVAMEKSGALLSRASSVFYNLAGSNSNPVLRKIQGEMAPKMAAHSDNINLNPALFARIEAIYNDRTNL
GLTPEAVRLVEVYHQRFIMAGAKLTDEQKVKIRALNEEQSTLTNEFSQRLLRLTKEIAVVVESKNELAGLTDSDITSAAN
DAKAAGHDGKYLINITNTTRQPVLASLENRELRQRIWEASANRGLTGENETASLVSRLAQLRAERAALLGYENWASYRLA
PQMAKTPEAVYSMFGSMVPAVVANTEKEAADIQAMIDKTGGKFELAPWDWEFYAEKVRQEKYALDGNSIRPYFEFNRVLE
DGVFYTLKELYGVTLKPRPDLPVYHPDVKAYEMFDADGSSMAIFYADYFAREGKRGGAWMSSFVGQSFLEGTKPVVVNVM
NIKKAPEGEPTFVSYNEVTTMFHEMGHGTHGMFSKVTYPSLAGTSVSRDFVEFPSTFEEDWAAHPKVLANYAKHYETGKP
IPDELLQKLLKSGSFNQGFDTLEYMAAALVDMEWHSLSPDAPLQDVATFEANALKKHGLNISAVPPRYKSTYFAHAFPGG
YSASYYAYMWSEILAADAFAYVQTQGGLNREIGMKYRKTIREVGNSIAPMEAYKNFRGQEPTTQGLLKRRGLDQAL

Sequences:

>Translated_716_residues
MRKRFIAIAIGATLTAGFMAGCSNTESKAPNAMSVQAQNPLFQVSSLQYQAPDFSLIKNEHFTPALEQGMAEHYQEILAI
ANNPAAASFDNTIVAMEKSGALLSRASSVFYNLAGSNSNPVLRKIQGEMAPKMAAHSDNINLNPALFARIEAIYNDRTNL
GLTPEAVRLVEVYHQRFIMAGAKLTDEQKVKIRALNEEQSTLTNEFSQRLLRLTKEIAVVVESKNELAGLTDSDITSAAN
DAKAAGHDGKYLINITNTTRQPVLASLENRELRQRIWEASANRGLTGENETASLVSRLAQLRAERAALLGYENWASYRLA
PQMAKTPEAVYSMFGSMVPAVVANTEKEAADIQAMIDKTGGKFELAPWDWEFYAEKVRQEKYALDGNSIRPYFEFNRVLE
DGVFYTLKELYGVTLKPRPDLPVYHPDVKAYEMFDADGSSMAIFYADYFAREGKRGGAWMSSFVGQSFLEGTKPVVVNVM
NIKKAPEGEPTFVSYNEVTTMFHEMGHGTHGMFSKVTYPSLAGTSVSRDFVEFPSTFEEDWAAHPKVLANYAKHYETGKP
IPDELLQKLLKSGSFNQGFDTLEYMAAALVDMEWHSLSPDAPLQDVATFEANALKKHGLNISAVPPRYKSTYFAHAFPGG
YSASYYAYMWSEILAADAFAYVQTQGGLNREIGMKYRKTIREVGNSIAPMEAYKNFRGQEPTTQGLLKRRGLDQAL
>Mature_716_residues
MRKRFIAIAIGATLTAGFMAGCSNTESKAPNAMSVQAQNPLFQVSSLQYQAPDFSLIKNEHFTPALEQGMAEHYQEILAI
ANNPAAASFDNTIVAMEKSGALLSRASSVFYNLAGSNSNPVLRKIQGEMAPKMAAHSDNINLNPALFARIEAIYNDRTNL
GLTPEAVRLVEVYHQRFIMAGAKLTDEQKVKIRALNEEQSTLTNEFSQRLLRLTKEIAVVVESKNELAGLTDSDITSAAN
DAKAAGHDGKYLINITNTTRQPVLASLENRELRQRIWEASANRGLTGENETASLVSRLAQLRAERAALLGYENWASYRLA
PQMAKTPEAVYSMFGSMVPAVVANTEKEAADIQAMIDKTGGKFELAPWDWEFYAEKVRQEKYALDGNSIRPYFEFNRVLE
DGVFYTLKELYGVTLKPRPDLPVYHPDVKAYEMFDADGSSMAIFYADYFAREGKRGGAWMSSFVGQSFLEGTKPVVVNVM
NIKKAPEGEPTFVSYNEVTTMFHEMGHGTHGMFSKVTYPSLAGTSVSRDFVEFPSTFEEDWAAHPKVLANYAKHYETGKP
IPDELLQKLLKSGSFNQGFDTLEYMAAALVDMEWHSLSPDAPLQDVATFEANALKKHGLNISAVPPRYKSTYFAHAFPGG
YSASYYAYMWSEILAADAFAYVQTQGGLNREIGMKYRKTIREVGNSIAPMEAYKNFRGQEPTTQGLLKRRGLDQAL

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=606, Percent_Identity=28.5478547854785, Blast_Score=235, Evalue=1e-61,
Organism=Homo sapiens, GI14149738, Length=608, Percent_Identity=28.4539473684211, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI156105687, Length=608, Percent_Identity=22.6973684210526, Blast_Score=157, Evalue=2e-38,
Organism=Escherichia coli, GI1787819, Length=676, Percent_Identity=45.5621301775148, Blast_Score=645, Evalue=0.0,
Organism=Escherichia coli, GI1789913, Length=685, Percent_Identity=31.2408759124088, Blast_Score=347, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI32565901, Length=418, Percent_Identity=24.1626794258373, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319793, Length=688, Percent_Identity=25.7267441860465, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6322715, Length=477, Percent_Identity=24.9475890985325, Blast_Score=131, Evalue=5e-31,
Organism=Drosophila melanogaster, GI21356111, Length=477, Percent_Identity=23.0607966457023, Blast_Score=162, Evalue=1e-39,
Organism=Drosophila melanogaster, GI20129717, Length=406, Percent_Identity=26.1083743842365, Blast_Score=144, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 79489; Mature: 79489

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKRFIAIAIGATLTAGFMAGCSNTESKAPNAMSVQAQNPLFQVSSLQYQAPDFSLIKNE
CCCEEEEEEECHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEECCCEECCCCHHHHCCC
HFTPALEQGMAEHYQEILAIANNPAAASFDNTIVAMEKSGALLSRASSVFYNLAGSNSNP
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHEEECCCCCCH
VLRKIQGEMAPKMAAHSDNINLNPALFARIEAIYNDRTNLGLTPEAVRLVEVYHQRFIMA
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHC
GAKLTDEQKVKIRALNEEQSTLTNEFSQRLLRLTKEIAVVVESKNELAGLTDSDITSAAN
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHEEEECCHHHCCCCCCHHHHCCC
DAKAAGHDGKYLINITNTTRQPVLASLENRELRQRIWEASANRGLTGENETASLVSRLAQ
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LRAERAALLGYENWASYRLAPQMAKTPEAVYSMFGSMVPAVVANTEKEAADIQAMIDKTG
HHHHHHHHHCCCCCCCCEECCHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
GKFELAPWDWEFYAEKVRQEKYALDGNSIRPYFEFNRVLEDGVFYTLKELYGVTLKPRPD
CEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LPVYHPDVKAYEMFDADGSSMAIFYADYFAREGKRGGAWMSSFVGQSFLEGTKPVVVNVM
CCCCCCCCCEEEEECCCCCEEEEEEEHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEE
NIKKAPEGEPTFVSYNEVTTMFHEMGHGTHGMFSKVTYPSLAGTSVSRDFVEFPSTFEED
ECCCCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHCCCHHHHH
WAAHPKVLANYAKHYETGKPIPDELLQKLLKSGSFNQGFDTLEYMAAALVDMEWHSLSPD
HCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHCCCCCC
APLQDVATFEANALKKHGLNISAVPPRYKSTYFAHAFPGGYSASYYAYMWSEILAADAFA
CCHHHHHHHHHHHHHHCCCCEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
YVQTQGGLNREIGMKYRKTIREVGNSIAPMEAYKNFRGQEPTTQGLLKRRGLDQAL
EEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRKRFIAIAIGATLTAGFMAGCSNTESKAPNAMSVQAQNPLFQVSSLQYQAPDFSLIKNE
CCCEEEEEEECHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEECCCEECCCCHHHHCCC
HFTPALEQGMAEHYQEILAIANNPAAASFDNTIVAMEKSGALLSRASSVFYNLAGSNSNP
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHEEECCCCCCH
VLRKIQGEMAPKMAAHSDNINLNPALFARIEAIYNDRTNLGLTPEAVRLVEVYHQRFIMA
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHC
GAKLTDEQKVKIRALNEEQSTLTNEFSQRLLRLTKEIAVVVESKNELAGLTDSDITSAAN
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHEEEECCHHHCCCCCCHHHHCCC
DAKAAGHDGKYLINITNTTRQPVLASLENRELRQRIWEASANRGLTGENETASLVSRLAQ
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LRAERAALLGYENWASYRLAPQMAKTPEAVYSMFGSMVPAVVANTEKEAADIQAMIDKTG
HHHHHHHHHCCCCCCCCEECCHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
GKFELAPWDWEFYAEKVRQEKYALDGNSIRPYFEFNRVLEDGVFYTLKELYGVTLKPRPD
CEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LPVYHPDVKAYEMFDADGSSMAIFYADYFAREGKRGGAWMSSFVGQSFLEGTKPVVVNVM
CCCCCCCCCEEEEECCCCCEEEEEEEHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEE
NIKKAPEGEPTFVSYNEVTTMFHEMGHGTHGMFSKVTYPSLAGTSVSRDFVEFPSTFEED
ECCCCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHCCCHHHHH
WAAHPKVLANYAKHYETGKPIPDELLQKLLKSGSFNQGFDTLEYMAAALVDMEWHSLSPD
HCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHCCCCCC
APLQDVATFEANALKKHGLNISAVPPRYKSTYFAHAFPGGYSASYYAYMWSEILAADAFA
CCHHHHHHHHHHHHHHCCCCEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
YVQTQGGLNREIGMKYRKTIREVGNSIAPMEAYKNFRGQEPTTQGLLKRRGLDQAL
EEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]