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The map label for this gene is dctB [H]

Identifier: 160876062

GI number: 160876062

Start: 3503558

End: 3505354

Strand: Direct

Name: dctB [H]

Synonym: Sbal195_2952

Alternate gene names: 160876062

Gene position: 3503558-3505354 (Clockwise)

Preceding gene: 160876061

Following gene: 160876063

Centisome position: 65.52

GC content: 47.08

Gene sequence:

>1797_bases
ATGTTGCCCATGACGCCTAAGGCCAAGAAACGCCTCTTTCTCACTGTAGTGTTACTTGCAGGCCTATTTGCAACACTCAA
ACTGACCTATTGGGTGCATTTACATCAAGGTAAAATCGAGATCCAAACCCAATCGGAGAAACAACTGAAGGAGTTAGTCA
GCTTTCTCGATGGTGCATTATCGCGCTACGAAAGCATTCCCCACGTGCTCTCAACTAACCCTATGCTCGCCAATGTACTG
AACGATCAACAAAACCCCGATAAGATCCAAGAACTTAATTTATATCTCGAAGAAATTCAGCATGTCACTGAGGCGTCCGA
TATCTATCTGATTGATGCCTTAGGCATCGCGATTGCCGCCAGTAACTGGCAACAAAGTTTCTCCTTTATTGGCAAGGATT
ATTCCTTTAGACCCTATTACACCGATGCTATTTCGGGCAATCTAGGCCGTTATTATGCCGTGGGCACCAGCTCAGATAAG
CGTGGGTTTTACTTTTCTTACCCTATTTATCAGCAAGGCGGCAAAGGCATACTCGGCGCGATCATTGTCAAAGTGGACAT
TAGCGGTATCGAGCAGCAAAGCACGAGCATTGCCATTGCGGGTCAATACCAATTCCTTATCAGCGACCCTGAAGACATTG
TTTTTATCTCCAGCGTTGATGAGTGGCGGTTAAAGTCACTCACTCCACTTACCCAAGCCAAACAATATGCGCTTAATGCA
TCAAAGCGTTACGCGGAACGCCCCATAGGCGAGCTATTAATGAAGCCGCCCTATGAGAGTGGCAGCCAAGCCATGCTCTA
CCAATTACAAACGGGCAGAGATCATGAGCAATACATGGATAATCATCAGTTGATGGCCAAAGCTGGCTGGCGGGTGCACA
TCTTAGCGCCCATCAAACCCTTGCTGTCGTCTTTACCTGCATTGATGTTACTGTCAGCCAGCATTTATCTGTTGCTGGCG
CTCAGCATCTTGTTTAGCACCGAGCGTCGCCGCAACCTACAGCGCATGCAGCTGGCACAAAGCCTATTAGAACAACGCGT
AGAAGAACGAACTCAGGACTTGCAGCAGGCGAACCATCAGCTTAAAGATACTCAGGATGAACTCATTCAAGCGGCAAAAC
TGACTGTGATCGGCAGTTTATCCGCCAGCATTAACCATGAGCTTAATCAGCCGCTTGCAGCACTGCGCAGCTACGCCCAA
AATACTCAAACCTTTCTAGCCCGTAATATGCAAGATAAGGCACTGGATAATATCAAGATTATTATTGAACTGACCGATAG
ATTGGCCGATATTGTCGGCCAATTTAAAAGCTTCACTCGCAAGAGCCAAGGCACGGATAGCGCCACCGATATTGGCCGCT
GTATCAAACAAGCGCTGACCATAGTTCAGCCCGCAATAGACAAGCAAGGCGTTGAACTCGATGTGCAGTTACCCAATGGC
AACTATCAGGTTTGGGGCGATAAAGTCCGATTACAGCAAGTGTTTGTCAATATCATGAGCAACGCCATTGTCGCTATGCA
ACAATCGGTTAAACGCAGCTTGGTCATCCGCGTGACCAGTGAAGATAAGTTCTGCATCAGCATCCAAGATTCTGGCCCTG
GCGTACGTGAAAGCCAAATGGAAAAAATATTCGAACCTTACTTTACCACTAACGAGCGCCACGGATTAGGGCTGGGCTTA
TCGATTTCACAGCGTATTATCGAATCCATGCAAGGCCAAATTAACGTTGCCAATGCCGAAGAGGGTGGCGCCATTTTCCA
GATTATTTTACCTATTTATTTGCTTGAGGAACGTTAG

Upstream 100 bases:

>100_bases
TTGATTACAGTTAGTTTTTAAGCGAGCCTAGTCAGGCTCGCTTTGTTTTATGATGTACAGTCTCAGTGATTGATACCGTC
GCTTTATCAGGATAGCCACC

Downstream 100 bases:

>100_bases
TCTTATGAGTGTGCCCAATTCCATCCAAGATTATTCTGTTCTCATCATCGACGATGAGCCACACATAGGCACAGTTCTCG
TTCAGCTATTTGAACTTGAG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MLPMTPKAKKRLFLTVVLLAGLFATLKLTYWVHLHQGKIEIQTQSEKQLKELVSFLDGALSRYESIPHVLSTNPMLANVL
NDQQNPDKIQELNLYLEEIQHVTEASDIYLIDALGIAIAASNWQQSFSFIGKDYSFRPYYTDAISGNLGRYYAVGTSSDK
RGFYFSYPIYQQGGKGILGAIIVKVDISGIEQQSTSIAIAGQYQFLISDPEDIVFISSVDEWRLKSLTPLTQAKQYALNA
SKRYAERPIGELLMKPPYESGSQAMLYQLQTGRDHEQYMDNHQLMAKAGWRVHILAPIKPLLSSLPALMLLSASIYLLLA
LSILFSTERRRNLQRMQLAQSLLEQRVEERTQDLQQANHQLKDTQDELIQAAKLTVIGSLSASINHELNQPLAALRSYAQ
NTQTFLARNMQDKALDNIKIIIELTDRLADIVGQFKSFTRKSQGTDSATDIGRCIKQALTIVQPAIDKQGVELDVQLPNG
NYQVWGDKVRLQQVFVNIMSNAIVAMQQSVKRSLVIRVTSEDKFCISIQDSGPGVRESQMEKIFEPYFTTNERHGLGLGL
SISQRIIESMQGQINVANAEEGGAIFQIILPIYLLEER

Sequences:

>Translated_598_residues
MLPMTPKAKKRLFLTVVLLAGLFATLKLTYWVHLHQGKIEIQTQSEKQLKELVSFLDGALSRYESIPHVLSTNPMLANVL
NDQQNPDKIQELNLYLEEIQHVTEASDIYLIDALGIAIAASNWQQSFSFIGKDYSFRPYYTDAISGNLGRYYAVGTSSDK
RGFYFSYPIYQQGGKGILGAIIVKVDISGIEQQSTSIAIAGQYQFLISDPEDIVFISSVDEWRLKSLTPLTQAKQYALNA
SKRYAERPIGELLMKPPYESGSQAMLYQLQTGRDHEQYMDNHQLMAKAGWRVHILAPIKPLLSSLPALMLLSASIYLLLA
LSILFSTERRRNLQRMQLAQSLLEQRVEERTQDLQQANHQLKDTQDELIQAAKLTVIGSLSASINHELNQPLAALRSYAQ
NTQTFLARNMQDKALDNIKIIIELTDRLADIVGQFKSFTRKSQGTDSATDIGRCIKQALTIVQPAIDKQGVELDVQLPNG
NYQVWGDKVRLQQVFVNIMSNAIVAMQQSVKRSLVIRVTSEDKFCISIQDSGPGVRESQMEKIFEPYFTTNERHGLGLGL
SISQRIIESMQGQINVANAEEGGAIFQIILPIYLLEER
>Mature_598_residues
MLPMTPKAKKRLFLTVVLLAGLFATLKLTYWVHLHQGKIEIQTQSEKQLKELVSFLDGALSRYESIPHVLSTNPMLANVL
NDQQNPDKIQELNLYLEEIQHVTEASDIYLIDALGIAIAASNWQQSFSFIGKDYSFRPYYTDAISGNLGRYYAVGTSSDK
RGFYFSYPIYQQGGKGILGAIIVKVDISGIEQQSTSIAIAGQYQFLISDPEDIVFISSVDEWRLKSLTPLTQAKQYALNA
SKRYAERPIGELLMKPPYESGSQAMLYQLQTGRDHEQYMDNHQLMAKAGWRVHILAPIKPLLSSLPALMLLSASIYLLLA
LSILFSTERRRNLQRMQLAQSLLEQRVEERTQDLQQANHQLKDTQDELIQAAKLTVIGSLSASINHELNQPLAALRSYAQ
NTQTFLARNMQDKALDNIKIIIELTDRLADIVGQFKSFTRKSQGTDSATDIGRCIKQALTIVQPAIDKQGVELDVQLPNG
NYQVWGDKVRLQQVFVNIMSNAIVAMQQSVKRSLVIRVTSEDKFCISIQDSGPGVRESQMEKIFEPYFTTNERHGLGLGL
SISQRIIESMQGQINVANAEEGGAIFQIILPIYLLEER

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=232, Percent_Identity=33.1896551724138, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=30.1724137931034, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI48994928, Length=240, Percent_Identity=25.4166666666667, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87081816, Length=272, Percent_Identity=22.7941176470588, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788393, Length=218, Percent_Identity=27.9816513761468, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790346, Length=222, Percent_Identity=25.2252252252252, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787894, Length=319, Percent_Identity=24.4514106583072, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790300, Length=241, Percent_Identity=26.5560165975104, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI145693157, Length=114, Percent_Identity=34.2105263157895, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790551, Length=210, Percent_Identity=26.1904761904762, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786912, Length=226, Percent_Identity=24.3362831858407, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789149, Length=262, Percent_Identity=24.8091603053435, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67266; Mature: 67266

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPMTPKAKKRLFLTVVLLAGLFATLKLTYWVHLHQGKIEIQTQSEKQLKELVSFLDGAL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCEEEEEECCHHHHHHHHHHHHHHH
SRYESIPHVLSTNPMLANVLNDQQNPDKIQELNLYLEEIQHVTEASDIYLIDALGIAIAA
HHHHCCCHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHH
SNWQQSFSFIGKDYSFRPYYTDAISGNLGRYYAVGTSSDKRGFYFSYPIYQQGGKGILGA
CCHHHHHHHHCCCCCCCCEECCCCCCCCCCEEEECCCCCCCCEEEECCHHHCCCCCEEEE
IIVKVDISGIEQQSTSIAIAGQYQFLISDPEDIVFISSVDEWRLKSLTPLTQAKQYALNA
EEEEEECCCCCCCCCEEEEEEEEEEEEECCCCEEEEECCCHHHHHHCCHHHHHHHHHHHH
SKRYAERPIGELLMKPPYESGSQAMLYQLQTGRDHEQYMDNHQLMAKAGWRVHILAPIKP
HHHHHHCCHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHCCHHHHHHCCCEEEEECCHHH
LLSSLPALMLLSASIYLLLALSILFSTERRRNLQRMQLAQSLLEQRVEERTQDLQQANHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKDTQDELIQAAKLTVIGSLSASINHELNQPLAALRSYAQNTQTFLARNMQDKALDNIKI
HCCCHHHHHHHHHHHEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEE
IIELTDRLADIVGQFKSFTRKSQGTDSATDIGRCIKQALTIVQPAIDKQGVELDVQLPNG
EEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
NYQVWGDKVRLQQVFVNIMSNAIVAMQQSVKRSLVIRVTSEDKFCISIQDSGPGVRESQM
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEEECCCCCCCHHHH
EKIFEPYFTTNERHGLGLGLSISQRIIESMQGQINVANAEEGGAIFQIILPIYLLEER
HHHHCCCCCCCCCCCCEECHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLPMTPKAKKRLFLTVVLLAGLFATLKLTYWVHLHQGKIEIQTQSEKQLKELVSFLDGAL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCEEEEEECCHHHHHHHHHHHHHHH
SRYESIPHVLSTNPMLANVLNDQQNPDKIQELNLYLEEIQHVTEASDIYLIDALGIAIAA
HHHHCCCHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHH
SNWQQSFSFIGKDYSFRPYYTDAISGNLGRYYAVGTSSDKRGFYFSYPIYQQGGKGILGA
CCHHHHHHHHCCCCCCCCEECCCCCCCCCCEEEECCCCCCCCEEEECCHHHCCCCCEEEE
IIVKVDISGIEQQSTSIAIAGQYQFLISDPEDIVFISSVDEWRLKSLTPLTQAKQYALNA
EEEEEECCCCCCCCCEEEEEEEEEEEEECCCCEEEEECCCHHHHHHCCHHHHHHHHHHHH
SKRYAERPIGELLMKPPYESGSQAMLYQLQTGRDHEQYMDNHQLMAKAGWRVHILAPIKP
HHHHHHCCHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHCCHHHHHHCCCEEEEECCHHH
LLSSLPALMLLSASIYLLLALSILFSTERRRNLQRMQLAQSLLEQRVEERTQDLQQANHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKDTQDELIQAAKLTVIGSLSASINHELNQPLAALRSYAQNTQTFLARNMQDKALDNIKI
HCCCHHHHHHHHHHHEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEE
IIELTDRLADIVGQFKSFTRKSQGTDSATDIGRCIKQALTIVQPAIDKQGVELDVQLPNG
EEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
NYQVWGDKVRLQQVFVNIMSNAIVAMQQSVKRSLVIRVTSEDKFCISIQDSGPGVRESQM
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEEECCCCCCCHHHH
EKIFEPYFTTNERHGLGLGLSISQRIIESMQGQINVANAEEGGAIFQIILPIYLLEER
HHHHCCCCCCCCCCCCEECHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]