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The map label for this gene is apr [H]

Identifier: 160875984

GI number: 160875984

Start: 3425842

End: 3428301

Strand: Direct

Name: apr [H]

Synonym: Sbal195_2874

Alternate gene names: 160875984

Gene position: 3425842-3428301 (Clockwise)

Preceding gene: 160875982

Following gene: 160875995

Centisome position: 64.07

GC content: 49.72

Gene sequence:

>2460_bases
ATGACAATCAACAGAACCACTAAAATAGCGTTAAGCCTTTCAAGCTTAGCTATTGCGATCTCAGCCGGTGTACAAGCAGC
ACCACAAGCCCCAGGTTTTGCCGCAGCATTACAAGCACAAACCTCTCCACTGCCAAAGCGTTACATTGTGAAATTTAAAA
ACGCCGATGCAGCGGCCATTATGTCGGCCAGCAATGTGCAATCAATGAGTGATCAGCAATCGAGCGACGCGACAACTGAC
GCGCTGCCAAGCACGATGAATTATCAGCCACAAATGGCGGAAATCAGTGCCCAGCACACTGCATTGAACAAAGTGCAAGC
GAAGGAAATGAAGCGTATCGGACGCAGTAACAGCTACTCGGTCAAACTCGATGCTAACGGCATCAATACCTTAAAAAAAC
GTGCCGATGTGGAATATGTTGAAGAAGACATGCCGCGTCACTTACTGAGTGAAAGCACACCCTGGGGCCAAACCTTTGTG
GGGGCGACTCAGCTAAGCGATAGCCAAGCGGGCAACCGCACGATTTGTATTATCGATTCTGGCTACGACCGTAGCCACAG
CGAATTAGGTGGCAATAATGTCACGGGTACCAATAACTCAGGTACAGGCAACTGGTTTGAGCCGGGCAACAACAACGCCC
ACGGTACTCACGTTGCGGGCACGATTGCGGCGATTGCTAACAATGACGGCGTGATCGGCGTAATGCCAAATCAAACTGCC
AATATTCATGTCGTAAAAGTGTTTAACGAATCGGGCTGGGGTTACTCTTCATCCTTAGTGGCCGCAGTAGATACTTGTGT
TGCCAACGGCGCTAACGTTGTCACTATGAGTTTAGGTGGCGCGGGTTCCAGCACCACTGAGCGTAACGCTCTGGCTGCAC
ATTATAACAATGGTGTGCTCTTGATTGCCGCTGCGGGTAACGCGGGTGACAGCACTCACAGCTACCCTGCATCCTACGAT
GGCGTGATGTCTGTTGCCTCTGTGGATAATCATAAAGACCACTCGGCATTTTCCCAATACACCAACCAAGTGGAAATATC
TGGCCCAGGTGAAGCGATTCTGTCGACGGTTACCCGTGGCGAAGGCCGTTTAGCCGATATCACTATCGGTGGTCAGTCTT
ACTTTGATTCAGGTGTCGTGCCACATAATCGCCTTATTTCATCGGGCGGCAGCTATGTTCCTGCGCCATACAATGGCACA
GCGACAGCCACACTTGCCGAATGTAGCGTCAGCGGAACTAGCTTCAACTGCGGCAACATGACCAATAAAATCTGTTTAGT
GGAGCGTGTTGGCAATCAAGGCACAAGTTACCCTGAAATCAATGCGGCTAAAGCCTGTAAAAATGCTGGTGCCAGTGCGG
CGATTGTTTACAGTAACGCGGCATTACCGGGCTTACAAAACCCCTTCCTTGTCGATGCTAACAGTGAAATCAATATGGTT
TCCGTGTCTGTGGATCGCGCAACAGGTTTAGCACTACGTAATCAATTGGGCGCGACAGCAACAGTCAGCAACCAAGGTAA
TAAAGATTACGAGTACTACAACGGTACTTCGATGGCGACGCCACATGTGTCAGGTGTTGCAACTTTAGTCTGGAGCTATC
ACCCAGAGTGTAGTGCCGCGCAAGTTCGTAACGCATTGAAAATGACCGCCGAAGATCTTGGTACTGCGGGTCGTGACAAC
TACTATGGCTATGGTTTAGTCAATGCAGTTGCCGCGAAAACCTTCTTAGATGCCTCTTGTACTGGCCCAACGGGTCCGGT
TGATCCAACACCAACCGATGGCGTGTTAGTTAACGGTGTGGCTAAAACAGGCTTAGGCGGCGCAGCGAGTGAAGAACTGC
ACTTCTCCTTTGACGTACCACAAGGCGCAACTAATTTAGGCTTTGTAATGAACGGTGGTACAGGTGATGCGGACTTGTAT
GTGCAATATGGCGCAGCGCCAACTACAGCTAACTATGATTGTCGTCCGTATAAAAGTGGCAATAGCGAGTCTTGCCCAAT
CACCAATATCCAATCAGGCACTTACTACGCCATGCTGAAAGGCTACTCTGCCTTCACTGGTGTGTCGTTAACAGCAAGCT
ACACAGCATCTAGCGGCGGAACGCCACCGACTACGCCAGCAAGCTATAGCAACACTGATAACTACAACATCCCTGATAAC
AAAGCAGCAGGGATCACTAGCCCAATCACAGTCACTCGCACAGGTGATTCAGGCACTGTGACTGCGGTAGTGAACATAGT
CCACCCTTATATTGGTGACTTGAAAGTGCAGCTGATCAGCCCTTCTGGTAAAACAGTTACATTGCATAGCAACACAGGTT
CAGGTGCTGCCAATATCAACAAGAGCTATACCGCTGATATGACGGGTGCTAATTCGAACGGCGTATGGAAGTTAAAAGCC
GTAGACAGTGGCCGTGGTGATGTGGGTTATATCGATAGCTGGGAGCTGAGCTTCCAATAA

Upstream 100 bases:

>100_bases
CGCAGATAGATTCACTAACCGAGTAGCATCTGAGTCGTAGTTATTCTTATGAAACATAAAATAATAATGATTAACACTAA
ATTGACCATGGAAGAAGAAC

Downstream 100 bases:

>100_bases
ATCCAAATCGATACGCTTACTGAGAAATGAAAGTAATAAATGAAAAGAGCCTGCAATCGCAGGCTCTTTTTTACAAGACA
TGTTATGCAATATCTTTGAG

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 819; Mature: 818

Protein sequence:

>819_residues
MTINRTTKIALSLSSLAIAISAGVQAAPQAPGFAAALQAQTSPLPKRYIVKFKNADAAAIMSASNVQSMSDQQSSDATTD
ALPSTMNYQPQMAEISAQHTALNKVQAKEMKRIGRSNSYSVKLDANGINTLKKRADVEYVEEDMPRHLLSESTPWGQTFV
GATQLSDSQAGNRTICIIDSGYDRSHSELGGNNVTGTNNSGTGNWFEPGNNNAHGTHVAGTIAAIANNDGVIGVMPNQTA
NIHVVKVFNESGWGYSSSLVAAVDTCVANGANVVTMSLGGAGSSTTERNALAAHYNNGVLLIAAAGNAGDSTHSYPASYD
GVMSVASVDNHKDHSAFSQYTNQVEISGPGEAILSTVTRGEGRLADITIGGQSYFDSGVVPHNRLISSGGSYVPAPYNGT
ATATLAECSVSGTSFNCGNMTNKICLVERVGNQGTSYPEINAAKACKNAGASAAIVYSNAALPGLQNPFLVDANSEINMV
SVSVDRATGLALRNQLGATATVSNQGNKDYEYYNGTSMATPHVSGVATLVWSYHPECSAAQVRNALKMTAEDLGTAGRDN
YYGYGLVNAVAAKTFLDASCTGPTGPVDPTPTDGVLVNGVAKTGLGGAASEELHFSFDVPQGATNLGFVMNGGTGDADLY
VQYGAAPTTANYDCRPYKSGNSESCPITNIQSGTYYAMLKGYSAFTGVSLTASYTASSGGTPPTTPASYSNTDNYNIPDN
KAAGITSPITVTRTGDSGTVTAVVNIVHPYIGDLKVQLISPSGKTVTLHSNTGSGAANINKSYTADMTGANSNGVWKLKA
VDSGRGDVGYIDSWELSFQ

Sequences:

>Translated_819_residues
MTINRTTKIALSLSSLAIAISAGVQAAPQAPGFAAALQAQTSPLPKRYIVKFKNADAAAIMSASNVQSMSDQQSSDATTD
ALPSTMNYQPQMAEISAQHTALNKVQAKEMKRIGRSNSYSVKLDANGINTLKKRADVEYVEEDMPRHLLSESTPWGQTFV
GATQLSDSQAGNRTICIIDSGYDRSHSELGGNNVTGTNNSGTGNWFEPGNNNAHGTHVAGTIAAIANNDGVIGVMPNQTA
NIHVVKVFNESGWGYSSSLVAAVDTCVANGANVVTMSLGGAGSSTTERNALAAHYNNGVLLIAAAGNAGDSTHSYPASYD
GVMSVASVDNHKDHSAFSQYTNQVEISGPGEAILSTVTRGEGRLADITIGGQSYFDSGVVPHNRLISSGGSYVPAPYNGT
ATATLAECSVSGTSFNCGNMTNKICLVERVGNQGTSYPEINAAKACKNAGASAAIVYSNAALPGLQNPFLVDANSEINMV
SVSVDRATGLALRNQLGATATVSNQGNKDYEYYNGTSMATPHVSGVATLVWSYHPECSAAQVRNALKMTAEDLGTAGRDN
YYGYGLVNAVAAKTFLDASCTGPTGPVDPTPTDGVLVNGVAKTGLGGAASEELHFSFDVPQGATNLGFVMNGGTGDADLY
VQYGAAPTTANYDCRPYKSGNSESCPITNIQSGTYYAMLKGYSAFTGVSLTASYTASSGGTPPTTPASYSNTDNYNIPDN
KAAGITSPITVTRTGDSGTVTAVVNIVHPYIGDLKVQLISPSGKTVTLHSNTGSGAANINKSYTADMTGANSNGVWKLKA
VDSGRGDVGYIDSWELSFQ
>Mature_818_residues
TINRTTKIALSLSSLAIAISAGVQAAPQAPGFAAALQAQTSPLPKRYIVKFKNADAAAIMSASNVQSMSDQQSSDATTDA
LPSTMNYQPQMAEISAQHTALNKVQAKEMKRIGRSNSYSVKLDANGINTLKKRADVEYVEEDMPRHLLSESTPWGQTFVG
ATQLSDSQAGNRTICIIDSGYDRSHSELGGNNVTGTNNSGTGNWFEPGNNNAHGTHVAGTIAAIANNDGVIGVMPNQTAN
IHVVKVFNESGWGYSSSLVAAVDTCVANGANVVTMSLGGAGSSTTERNALAAHYNNGVLLIAAAGNAGDSTHSYPASYDG
VMSVASVDNHKDHSAFSQYTNQVEISGPGEAILSTVTRGEGRLADITIGGQSYFDSGVVPHNRLISSGGSYVPAPYNGTA
TATLAECSVSGTSFNCGNMTNKICLVERVGNQGTSYPEINAAKACKNAGASAAIVYSNAALPGLQNPFLVDANSEINMVS
VSVDRATGLALRNQLGATATVSNQGNKDYEYYNGTSMATPHVSGVATLVWSYHPECSAAQVRNALKMTAEDLGTAGRDNY
YGYGLVNAVAAKTFLDASCTGPTGPVDPTPTDGVLVNGVAKTGLGGAASEELHFSFDVPQGATNLGFVMNGGTGDADLYV
QYGAAPTTANYDCRPYKSGNSESCPITNIQSGTYYAMLKGYSAFTGVSLTASYTASSGGTPPTTPASYSNTDNYNIPDNK
AAGITSPITVTRTGDSGTVTAVVNIVHPYIGDLKVQLISPSGKTVTLHSNTGSGAANINKSYTADMTGANSNGVWKLKAV
DSGRGDVGYIDSWELSFQ

Specific function: Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8 [H]

EC number: =3.4.21.62 [H]

Molecular weight: Translated: 84819; Mature: 84688

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTINRTTKIALSLSSLAIAISAGVQAAPQAPGFAAALQAQTSPLPKRYIVKFKNADAAAI
CCCCCEEEEEEEHHHEEEEEECCCCCCCCCCCHHHHHCCCCCCCCCEEEEEECCCCCEEE
MSASNVQSMSDQQSSDATTDALPSTMNYQPQMAEISAQHTALNKVQAKEMKRIGRSNSYS
EEHHHHHHHHCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VKLDANGINTLKKRADVEYVEEDMPRHLLSESTPWGQTFVGATQLSDSQAGNRTICIIDS
EEEECCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEEC
GYDRSHSELGGNNVTGTNNSGTGNWFEPGNNNAHGTHVAGTIAAIANNDGVIGVMPNQTA
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEECCCCCC
NIHVVKVFNESGWGYSSSLVAAVDTCVANGANVVTMSLGGAGSSTTERNALAAHYNNGVL
CEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEECCCEE
LIAAAGNAGDSTHSYPASYDGVMSVASVDNHKDHSAFSQYTNQVEISGPGEAILSTVTRG
EEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHCCEEEECCCHHHHHHHHHCC
EGRLADITIGGQSYFDSGVVPHNRLISSGGSYVPAPYNGTATATLAECSVSGTSFNCGNM
CCEEEEEEECCHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCEEECCCC
TNKICLVERVGNQGTSYPEINAAKACKNAGASAAIVYSNAALPGLQNPFLVDANSEINMV
CCCEEEEEECCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCEEEECCCCEEEE
SVSVDRATGLALRNQLGATATVSNQGNKDYEYYNGTSMATPHVSGVATLVWSYHPECSAA
EEEECCHHHHHHHHHCCCEEEECCCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCCHH
QVRNALKMTAEDLGTAGRDNYYGYGLVNAVAAKTFLDASCTGPTGPVDPTPTDGVLVNGV
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECH
AKTGLGGAASEELHFSFDVPQGATNLGFVMNGGTGDADLYVQYGAAPTTANYDCRPYKSG
HHCCCCCCCCCCEEEEEECCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCC
NSESCPITNIQSGTYYAMLKGYSAFTGVSLTASYTASSGGTPPTTPASYSNTDNYNIPDN
CCCCCCEEEECCCEEEEEEECCCHHCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
KAAGITSPITVTRTGDSGTVTAVVNIVHPYIGDLKVQLISPSGKTVTLHSNTGSGAANIN
CCCCCCCCEEEEEECCCCEEEEEEEHHHCCCCCEEEEEECCCCCEEEEECCCCCCCCCCC
KSYTADMTGANSNGVWKLKAVDSGRGDVGYIDSWELSFQ
CCEEEEECCCCCCCEEEEEEECCCCCCCCEEECEEEECC
>Mature Secondary Structure 
TINRTTKIALSLSSLAIAISAGVQAAPQAPGFAAALQAQTSPLPKRYIVKFKNADAAAI
CCCCEEEEEEEHHHEEEEEECCCCCCCCCCCHHHHHCCCCCCCCCEEEEEECCCCCEEE
MSASNVQSMSDQQSSDATTDALPSTMNYQPQMAEISAQHTALNKVQAKEMKRIGRSNSYS
EEHHHHHHHHCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VKLDANGINTLKKRADVEYVEEDMPRHLLSESTPWGQTFVGATQLSDSQAGNRTICIIDS
EEEECCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEEC
GYDRSHSELGGNNVTGTNNSGTGNWFEPGNNNAHGTHVAGTIAAIANNDGVIGVMPNQTA
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEECCCCCC
NIHVVKVFNESGWGYSSSLVAAVDTCVANGANVVTMSLGGAGSSTTERNALAAHYNNGVL
CEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEECCCEE
LIAAAGNAGDSTHSYPASYDGVMSVASVDNHKDHSAFSQYTNQVEISGPGEAILSTVTRG
EEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHCCEEEECCCHHHHHHHHHCC
EGRLADITIGGQSYFDSGVVPHNRLISSGGSYVPAPYNGTATATLAECSVSGTSFNCGNM
CCEEEEEEECCHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCEEECCCC
TNKICLVERVGNQGTSYPEINAAKACKNAGASAAIVYSNAALPGLQNPFLVDANSEINMV
CCCEEEEEECCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCEEEECCCCEEEE
SVSVDRATGLALRNQLGATATVSNQGNKDYEYYNGTSMATPHVSGVATLVWSYHPECSAA
EEEECCHHHHHHHHHCCCEEEECCCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCCHH
QVRNALKMTAEDLGTAGRDNYYGYGLVNAVAAKTFLDASCTGPTGPVDPTPTDGVLVNGV
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECH
AKTGLGGAASEELHFSFDVPQGATNLGFVMNGGTGDADLYVQYGAAPTTANYDCRPYKSG
HHCCCCCCCCCCEEEEEECCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCC
NSESCPITNIQSGTYYAMLKGYSAFTGVSLTASYTASSGGTPPTTPASYSNTDNYNIPDN
CCCCCCEEEECCCEEEEEEECCCHHCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
KAAGITSPITVTRTGDSGTVTAVVNIVHPYIGDLKVQLISPSGKTVTLHSNTGSGAANIN
CCCCCCCCEEEEEECCCCEEEEEEEHHHCCCCCEEEEEECCCCCEEEEECCCCCCCCCCC
KSYTADMTGANSNGVWKLKAVDSGRGDVGYIDSWELSFQ
CCEEEEECCCCCCCEEEEEEECCCCCCCCEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3001653; 4967581; 8512925; 9425066 [H]