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The map label for this gene is iorA [H]

Identifier: 160875934

GI number: 160875934

Start: 3361229

End: 3361747

Strand: Reverse

Name: iorA [H]

Synonym: Sbal195_2823

Alternate gene names: 160875934

Gene position: 3361747-3361229 (Counterclockwise)

Preceding gene: 160875935

Following gene: 160875933

Centisome position: 62.87

GC content: 51.45

Gene sequence:

>519_bases
ATGGCAGAAGTTTTATCAACCAAAGCAGTCGTCAAGGAAGCGAATACCGTCGCTTCCACCCAGACACTTTCCGCTCAGAC
ACTGACCATCAACGGTAAATCATTTACCTTAGATGCCGATCCTAAAATGCCAATCCTGTGGGCACTACGGGATATTTTAG
GGCTCACGGGCACTAAATATGGCTGCGGTGCAGGGCTATGCGGTGCTTGCACTGTGCATTTAGACGGCCAACCCGTACGC
GCCTGTTTAACCAGTTTGGGGCAGGCACAAGGAAAACGTCTGACAACAATTGAAGGGCTAGATAATCAAAAGCTTAAAAA
TGCTTGGGCCGAACATAACGTGCCCCAGTGCGGCTATTGTCAGGCGGGCCAACTGATGTCGGCTGCGGCGTTAGTGGCGC
AGCATCCGAAACCTTCTGAAGAACAAATCAACTCGGCCATGTCGGGGAATATCTGCCGCTGCGGTACATACCCGCGGATT
AAAGCGGCACTGCAAAACTATGCCAAACAGGAGGGCTAA

Upstream 100 bases:

>100_bases
ACAGCAGGGAGCGTTAGTCGCTATAACACTACCCCGCGCCGCAATTGATATTGATACCCAAGCCGATCTTGCGTCGTGGT
TGGCACTTAAGGAGTGAGTT

Downstream 100 bases:

>100_bases
TATGAGTACTTTTACTGCCGTAGAAAATATCAGCCGCCGCGATGTGTTAAAACTGTTTGGCGCAGTGGGTGGCGGATTAG
CATTAGGGGCGAGTGGACTA

Product: 2Fe-2S iron-sulfur cluster-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MAEVLSTKAVVKEANTVASTQTLSAQTLTINGKSFTLDADPKMPILWALRDILGLTGTKYGCGAGLCGACTVHLDGQPVR
ACLTSLGQAQGKRLTTIEGLDNQKLKNAWAEHNVPQCGYCQAGQLMSAAALVAQHPKPSEEQINSAMSGNICRCGTYPRI
KAALQNYAKQEG

Sequences:

>Translated_172_residues
MAEVLSTKAVVKEANTVASTQTLSAQTLTINGKSFTLDADPKMPILWALRDILGLTGTKYGCGAGLCGACTVHLDGQPVR
ACLTSLGQAQGKRLTTIEGLDNQKLKNAWAEHNVPQCGYCQAGQLMSAAALVAQHPKPSEEQINSAMSGNICRCGTYPRI
KAALQNYAKQEG
>Mature_171_residues
AEVLSTKAVVKEANTVASTQTLSAQTLTINGKSFTLDADPKMPILWALRDILGLTGTKYGCGAGLCGACTVHLDGQPVRA
CLTSLGQAQGKRLTTIEGLDNQKLKNAWAEHNVPQCGYCQAGQLMSAAALVAQHPKPSEEQINSAMSGNICRCGTYPRIK
AALQNYAKQEG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=156, Percent_Identity=35.8974358974359, Blast_Score=71, Evalue=4e-13,
Organism=Homo sapiens, GI71773480, Length=101, Percent_Identity=32.6732673267327, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786480, Length=163, Percent_Identity=40.4907975460123, Blast_Score=116, Evalue=9e-28,
Organism=Escherichia coli, GI1789232, Length=141, Percent_Identity=38.2978723404255, Blast_Score=89, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17539860, Length=155, Percent_Identity=36.7741935483871, Blast_Score=103, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI32566215, Length=165, Percent_Identity=35.7575757575758, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17540638, Length=176, Percent_Identity=34.0909090909091, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI17737937, Length=157, Percent_Identity=36.3057324840764, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24647193, Length=163, Percent_Identity=35.5828220858896, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=33.5483870967742, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647195, Length=160, Percent_Identity=32.5, Blast_Score=76, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24647197, Length=160, Percent_Identity=32.5, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24647199, Length=154, Percent_Identity=32.4675324675325, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 18178; Mature: 18047

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVLSTKAVVKEANTVASTQTLSAQTLTINGKSFTLDADPKMPILWALRDILGLTGTKY
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCCCCHHHHHHHHHHHCCCCCC
GCGAGLCGACTVHLDGQPVRACLTSLGQAQGKRLTTIEGLDNQKLKNAWAEHNVPQCGYC
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCC
QAGQLMSAAALVAQHPKPSEEQINSAMSGNICRCGTYPRIKAALQNYAKQEG
CHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEVLSTKAVVKEANTVASTQTLSAQTLTINGKSFTLDADPKMPILWALRDILGLTGTKY
CCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCCCCHHHHHHHHHHHCCCCCC
GCGAGLCGACTVHLDGQPVRACLTSLGQAQGKRLTTIEGLDNQKLKNAWAEHNVPQCGYC
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCC
QAGQLMSAAALVAQHPKPSEEQINSAMSGNICRCGTYPRIKAALQNYAKQEG
CHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]