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The map label for this gene is fhuE [H]

Identifier: 160875923

GI number: 160875923

Start: 3347760

End: 3350003

Strand: Direct

Name: fhuE [H]

Synonym: Sbal195_2812

Alternate gene names: 160875923

Gene position: 3347760-3350003 (Clockwise)

Preceding gene: 160875922

Following gene: 160875924

Centisome position: 62.61

GC content: 49.38

Gene sequence:

>2244_bases
ATGGAATTAAAGATCACCATTATGAAGACTTTCCCTCTCTCCAGCATCGCACTCGTCTGCAGACAAGCCCTCGTTAACCC
AAAACTATTGCTGTGCTCAGCCATGTTAGCCAGTGTGCCCCATGCCGTAGCAGACACTCTGGATGCGGATGGTAAAACCA
AGAAGCACCAAAAAGAAATTGAAATCATCAATGTCATTGGCGCTAAGGATTTACACGACAATCGCTATAAAACCCAAGCG
ATGAACACGGCAACTGGGCTCGATTTATCCTATTTAGAAACGCCGCAGTCGGTCACGTCTATCACCCGTCAAATGATGAA
CGATCAACAGCTTAATAGTGTGATTGATGCTATGACCAGCGTCGCGGGGATCAATGCCCGCCCAATGGATAACGACAGAT
ACAGCATTAGTGCCCGCGGTATTGCCGTGACCAGCATTTTGTACGATGGCGTGCCCACCACCTACGACACCCGCTTCAAC
TATGGGGATAACCTCATCGACACCGCCATCTACGAGCGAGTTGAAGTGGTACGCGGCGCGACGGGACTCATGACGGGAGC
CGGTAATCCATCGGCGGCGATTAATCTTATCCGTAAACGCCCGACCCAAGAGTTTATGGGCAGCACCTCGTTAAGCGTGG
GCTCATGGAATAATGTGCGTGGTATGGTCGATCTTTCGAGCGGCTTAAATGATTCGGGTTCTGTGCGCGGTCGCGTGGTG
GCCGCCTATCAGGATAAAGATTCATTCCAAGACAGATATGAGCAGCAGCGCACCACCTTATACGGCATAGTCGAAACCGA
TATTGGCGATAGCACCTTGTTCACCCTAGGGGTTGATTACCAAGATGCCACACCGAGCGGCACTATGTCGGGCGGCTTAC
CACTATTTTACAGTGATGGCAGCCGCACTAACTATGATCGCGCCACTTCAACAGCGCCCGATTGGGGCTCGGCGCATACC
CAAGGCCTCAACACCTTTGCCAGTCTAGAACACAGATTTGATAATGGCTGGAACCTAAAAGGGACTTACACTTATGGAGA
CAACTCGTTGAAGTTCGATGTGCTATGGGCCACGGGCTATCCCGATCCTGTAACCAATATCGGCGCAACAGCAGGCTCTA
TTGCCTATGTCGACGGCAGTCGCACCCAACACAATGTGGATTTGCGCGCCGAAGGACAATTCCAGCTCTTTGGTCAGGAA
CATCAATTGATGTTTGGCTGGAATGGCCAACGCCAAGAGTTCGCCAATCCCTACTATAATCCCACAGTAAAGGCGCCACC
ACTGGGAGATTTTCGCGATCCGAACTTCCAGTACCCTAAACCTCAATGGCAAGATACCTCAGACATTGGCTCATCTGGCG
AAACCAAGCAGAGTGCCGCCTATGTGGCGACGCAGCTCAATCTCAGCGACGCTTTAGCTGTCCTCGTCGGATTACGCCTC
AATGAGTGGGAAACCGACCAAGATAACTTTAAAAGCCTATACAATTTCAACATCAACAACGAACTCACTACTTACTTCGG
CCTCACATACGCTCTGACCGAGCAATATTCGCTTTATGCCAGCTATACCGACATTTTTGCGCCGCAAACTAAACAAAGAA
TCGATAAAAGCTATCTAGATCCGGTCAAAGGGAAAAACTACGAAGGTGGGATTAAGGCGAGCCTGTTCGATGAGGCTTTA
GATATGTCGCTATCGGTGTTTGAGATCAGGCAAGACAATCTTGGAATCAGCACTGGCGATGTGATCCCAGGAACCACAAC
GCAAGTGTATGAAGGCGTAAACGGTACAAAAACACAGGGATTCGAATTTGAATCAACAGGTAAAATCACTGATGACTGGA
ATGTTTACTTAGGCTACACCCAGTTCACCACCGAAGATCCTAAGGGCAAACGCATCAATACCACATCACCACGTCAGCAG
TTAAAACTCTTCACCACTTATACCTTTGGTGGTGATTGGCATAAATTGCAAATTGGTGCAGGGGTTAACTGGCAGAGCCG
CGTCTACCAAGAGGCTGATAAACCGGTAGGCAATGGTATAGACAAGATTAGAGTCGAAGTCGAGCAAGACTCCTATGCAC
TGGCAAGTTTGATGGCAAGTTACGCCTTCACCGAGCAACTTAAGCTTAGCGCCAACCTGCACAACGCCTTAGATAAAACC
TACTACAGCCAAGTCGGTCAATACAGCCAATTCCAATACGGTACGCCGCGCAGTGCCAACATAACCTTGGACTATCGCTT
CTAA

Upstream 100 bases:

>100_bases
CGTTAACGCGCAACAAAGCAAATAGACCCGACACTTTCTGAAACTTGACGAAACGTTTGTGTGGGCCACTTGTTGGCCCG
CATTATTAACCCCAACCTAA

Downstream 100 bases:

>100_bases
GTCAGACTTTTATTGAGATAGTTCGAAACCCCTTGTGAGCCCAAATCTTGGGCCCACAAGGTCCTCATCTATTGGACTTA
TCAATAATAGCGTGGCTTAT

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: Outer-membrane receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid [H]

Number of amino acids: Translated: 747; Mature: 747

Protein sequence:

>747_residues
MELKITIMKTFPLSSIALVCRQALVNPKLLLCSAMLASVPHAVADTLDADGKTKKHQKEIEIINVIGAKDLHDNRYKTQA
MNTATGLDLSYLETPQSVTSITRQMMNDQQLNSVIDAMTSVAGINARPMDNDRYSISARGIAVTSILYDGVPTTYDTRFN
YGDNLIDTAIYERVEVVRGATGLMTGAGNPSAAINLIRKRPTQEFMGSTSLSVGSWNNVRGMVDLSSGLNDSGSVRGRVV
AAYQDKDSFQDRYEQQRTTLYGIVETDIGDSTLFTLGVDYQDATPSGTMSGGLPLFYSDGSRTNYDRATSTAPDWGSAHT
QGLNTFASLEHRFDNGWNLKGTYTYGDNSLKFDVLWATGYPDPVTNIGATAGSIAYVDGSRTQHNVDLRAEGQFQLFGQE
HQLMFGWNGQRQEFANPYYNPTVKAPPLGDFRDPNFQYPKPQWQDTSDIGSSGETKQSAAYVATQLNLSDALAVLVGLRL
NEWETDQDNFKSLYNFNINNELTTYFGLTYALTEQYSLYASYTDIFAPQTKQRIDKSYLDPVKGKNYEGGIKASLFDEAL
DMSLSVFEIRQDNLGISTGDVIPGTTTQVYEGVNGTKTQGFEFESTGKITDDWNVYLGYTQFTTEDPKGKRINTTSPRQQ
LKLFTTYTFGGDWHKLQIGAGVNWQSRVYQEADKPVGNGIDKIRVEVEQDSYALASLMASYAFTEQLKLSANLHNALDKT
YYSQVGQYSQFQYGTPRSANITLDYRF

Sequences:

>Translated_747_residues
MELKITIMKTFPLSSIALVCRQALVNPKLLLCSAMLASVPHAVADTLDADGKTKKHQKEIEIINVIGAKDLHDNRYKTQA
MNTATGLDLSYLETPQSVTSITRQMMNDQQLNSVIDAMTSVAGINARPMDNDRYSISARGIAVTSILYDGVPTTYDTRFN
YGDNLIDTAIYERVEVVRGATGLMTGAGNPSAAINLIRKRPTQEFMGSTSLSVGSWNNVRGMVDLSSGLNDSGSVRGRVV
AAYQDKDSFQDRYEQQRTTLYGIVETDIGDSTLFTLGVDYQDATPSGTMSGGLPLFYSDGSRTNYDRATSTAPDWGSAHT
QGLNTFASLEHRFDNGWNLKGTYTYGDNSLKFDVLWATGYPDPVTNIGATAGSIAYVDGSRTQHNVDLRAEGQFQLFGQE
HQLMFGWNGQRQEFANPYYNPTVKAPPLGDFRDPNFQYPKPQWQDTSDIGSSGETKQSAAYVATQLNLSDALAVLVGLRL
NEWETDQDNFKSLYNFNINNELTTYFGLTYALTEQYSLYASYTDIFAPQTKQRIDKSYLDPVKGKNYEGGIKASLFDEAL
DMSLSVFEIRQDNLGISTGDVIPGTTTQVYEGVNGTKTQGFEFESTGKITDDWNVYLGYTQFTTEDPKGKRINTTSPRQQ
LKLFTTYTFGGDWHKLQIGAGVNWQSRVYQEADKPVGNGIDKIRVEVEQDSYALASLMASYAFTEQLKLSANLHNALDKT
YYSQVGQYSQFQYGTPRSANITLDYRF
>Mature_747_residues
MELKITIMKTFPLSSIALVCRQALVNPKLLLCSAMLASVPHAVADTLDADGKTKKHQKEIEIINVIGAKDLHDNRYKTQA
MNTATGLDLSYLETPQSVTSITRQMMNDQQLNSVIDAMTSVAGINARPMDNDRYSISARGIAVTSILYDGVPTTYDTRFN
YGDNLIDTAIYERVEVVRGATGLMTGAGNPSAAINLIRKRPTQEFMGSTSLSVGSWNNVRGMVDLSSGLNDSGSVRGRVV
AAYQDKDSFQDRYEQQRTTLYGIVETDIGDSTLFTLGVDYQDATPSGTMSGGLPLFYSDGSRTNYDRATSTAPDWGSAHT
QGLNTFASLEHRFDNGWNLKGTYTYGDNSLKFDVLWATGYPDPVTNIGATAGSIAYVDGSRTQHNVDLRAEGQFQLFGQE
HQLMFGWNGQRQEFANPYYNPTVKAPPLGDFRDPNFQYPKPQWQDTSDIGSSGETKQSAAYVATQLNLSDALAVLVGLRL
NEWETDQDNFKSLYNFNINNELTTYFGLTYALTEQYSLYASYTDIFAPQTKQRIDKSYLDPVKGKNYEGGIKASLFDEAL
DMSLSVFEIRQDNLGISTGDVIPGTTTQVYEGVNGTKTQGFEFESTGKITDDWNVYLGYTQFTTEDPKGKRINTTSPRQQ
LKLFTTYTFGGDWHKLQIGAGVNWQSRVYQEADKPVGNGIDKIRVEVEQDSYALASLMASYAFTEQLKLSANLHNALDKT
YYSQVGQYSQFQYGTPRSANITLDYRF

Specific function: Required for the uptake of Fe(3+) via coprogen, ferrioxamine B, and rhodotorulic acid [H]

COG id: COG4773

COG function: function code P; Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787344, Length=741, Percent_Identity=36.0323886639676, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI1786344, Length=700, Percent_Identity=21.7142857142857, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787024, Length=740, Percent_Identity=20.9459459459459, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 82914; Mature: 82914

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKITIMKTFPLSSIALVCRQALVNPKLLLCSAMLASVPHAVADTLDADGKTKKHQKEI
CEEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHE
EIINVIGAKDLHDNRYKTQAMNTATGLDLSYLETPQSVTSITRQMMNDQQLNSVIDAMTS
EEEEEECCCCCCCCCHHHHHHCCCCCCEEHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHH
VAGINARPMDNDRYSISARGIAVTSILYDGVPTTYDTRFNYGDNLIDTAIYERVEVVRGA
HCCCCCCCCCCCCEEEEECCEEEEEHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHCC
TGLMTGAGNPSAAINLIRKRPTQEFMGSTSLSVGSWNNVRGMVDLSSGLNDSGSVRGRVV
CCEEECCCCHHHHHHHHHHCCCHHHHCCCCEECCCCCCCCEEEEECCCCCCCCCCCEEEE
AAYQDKDSFQDRYEQQRTTLYGIVETDIGDSTLFTLGVDYQDATPSGTMSGGLPLFYSDG
EEECCCHHHHHHHHHHCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCC
SRTNYDRATSTAPDWGSAHTQGLNTFASLEHRFDNGWNLKGTYTYGDNSLKFDVLWATGY
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEECCC
PDPVTNIGATAGSIAYVDGSRTQHNVDLRAEGQFQLFGQEHQLMFGWNGQRQEFANPYYN
CCCHHHCCCCCCEEEEEECCCCCCCEEEEECCCEEEECCCCEEEEECCCCHHHHCCCCCC
PTVKAPPLGDFRDPNFQYPKPQWQDTSDIGSSGETKQSAAYVATQLNLSDALAVLVGLRL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHEEEEEECCHHHHHHHHHHCCC
NEWETDQDNFKSLYNFNINNELTTYFGLTYALTEQYSLYASYTDIFAPQTKQRIDKSYLD
CCCCCCHHHHHHHEECCCCCCEEHHHEEEEEECCCCEEEEEHHHHCCCCHHHHHHHHHCC
PVKGKNYEGGIKASLFDEALDMSLSVFEIRQDNLGISTGDVIPGTTTQVYEGVNGTKTQG
CCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHCCCCCCCCCC
FEFESTGKITDDWNVYLGYTQFTTEDPKGKRINTTSPRQQLKLFTTYTFGGDWHKLQIGA
EEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHEEEEEEEEECCCEEEEEECC
GVNWQSRVYQEADKPVGNGIDKIRVEVEQDSYALASLMASYAFTEQLKLSANLHNALDKT
CCCHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YYSQVGQYSQFQYGTPRSANITLDYRF
HHHHHCCCCCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MELKITIMKTFPLSSIALVCRQALVNPKLLLCSAMLASVPHAVADTLDADGKTKKHQKEI
CEEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHE
EIINVIGAKDLHDNRYKTQAMNTATGLDLSYLETPQSVTSITRQMMNDQQLNSVIDAMTS
EEEEEECCCCCCCCCHHHHHHCCCCCCEEHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHH
VAGINARPMDNDRYSISARGIAVTSILYDGVPTTYDTRFNYGDNLIDTAIYERVEVVRGA
HCCCCCCCCCCCCEEEEECCEEEEEHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHCC
TGLMTGAGNPSAAINLIRKRPTQEFMGSTSLSVGSWNNVRGMVDLSSGLNDSGSVRGRVV
CCEEECCCCHHHHHHHHHHCCCHHHHCCCCEECCCCCCCCEEEEECCCCCCCCCCCEEEE
AAYQDKDSFQDRYEQQRTTLYGIVETDIGDSTLFTLGVDYQDATPSGTMSGGLPLFYSDG
EEECCCHHHHHHHHHHCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCC
SRTNYDRATSTAPDWGSAHTQGLNTFASLEHRFDNGWNLKGTYTYGDNSLKFDVLWATGY
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEECCC
PDPVTNIGATAGSIAYVDGSRTQHNVDLRAEGQFQLFGQEHQLMFGWNGQRQEFANPYYN
CCCHHHCCCCCCEEEEEECCCCCCCEEEEECCCEEEECCCCEEEEECCCCHHHHCCCCCC
PTVKAPPLGDFRDPNFQYPKPQWQDTSDIGSSGETKQSAAYVATQLNLSDALAVLVGLRL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHEEEEEECCHHHHHHHHHHCCC
NEWETDQDNFKSLYNFNINNELTTYFGLTYALTEQYSLYASYTDIFAPQTKQRIDKSYLD
CCCCCCHHHHHHHEECCCCCCEEHHHEEEEEECCCCEEEEEHHHHCCCCHHHHHHHHHCC
PVKGKNYEGGIKASLFDEALDMSLSVFEIRQDNLGISTGDVIPGTTTQVYEGVNGTKTQG
CCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHCCCCCCCCCC
FEFESTGKITDDWNVYLGYTQFTTEDPKGKRINTTSPRQQLKLFTTYTFGGDWHKLQIGA
EEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHEEEEEEEEECCCEEEEEECC
GVNWQSRVYQEADKPVGNGIDKIRVEVEQDSYALASLMASYAFTEQLKLSANLHNALDKT
CCCHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YYSQVGQYSQFQYGTPRSANITLDYRF
HHHHHCCCCCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162465; 8905232; 9278503; 3032906 [H]