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The map label for this gene is mdtA [H]

Identifier: 160875777

GI number: 160875777

Start: 3162433

End: 3163515

Strand: Reverse

Name: mdtA [H]

Synonym: Sbal195_2665

Alternate gene names: 160875777

Gene position: 3163515-3162433 (Counterclockwise)

Preceding gene: 160875778

Following gene: 160875776

Centisome position: 59.16

GC content: 46.81

Gene sequence:

>1083_bases
ATGAAAAAAATTATTCTAATAATCGCCCTATTGGCCGCGGCATGGTTTGGATATCAAGCCATGCAACCGCAAGAGATTGC
CACTGCGCAAATGAAACTCATGCCTAACGTGGTGATTGCCACCGCCGCCATGGAACCTATTCGCGATGAAGTGGAAGCCA
TCGGCACCAATAAAGCCGCAGAATCTGTGACTATAACCCCTAAAGTTACCGACATGGTGATAGCACTTAAGTTTGATGAT
GGCGACATAGTCAAAAAGGGTGACTTGCTAGTCCAACTGCAAAATGCTGAGCAAATCGCTAAGGTTAAAGCCGCACAAGT
TAAAGTCAGTGATAATCAACGTGAATTCAACCGTATCAGTTCGTTAGTCACCAGCCGCACTGTGGCAGAGTTAGAACGCG
ACAGATTACAAACCCTTATCGATACCACCCGCGCAGAGCTTGAACAGGCGCAAGCATCACTCAATGATCGCAGTATTCTG
GCGCCTTTTAATGGCCGTTTAGGTTTACGCCAAATCAGTGTCGGTAGCCTAGTATCGCCCGGCACTGCGATCACTACCTT
GGATGATATCTCTAAGATTAAACTCGATTTTTCAGTGCCTGAGCGTTTTATTCAAGATTTAGCCCCAGGTAAGAAAGTTG
AAGCTAAAGCCGTGGCCTTTCCTGATTTTACCTTCAAAGGCGTGGTGACATCGATTGATAGCCGCGTAAACCCAACGACG
CGCACTGTGATTGTCCGCGCTGAAATTCCCAATCCTGAGCTTCGTTTATTACCGGGCATGTTGATGAAGGTCAAACTCAT
CAAACGTAGCCGCGAAGCCTTGATGTTGCCAGAATCTGCCATTATCCCAATCCAAAATGATCACTTTGTTTACAGCGTTA
ATGCCGACAATGTGATTGAGCGTAAACAAGTCACTATTGGGATTCGTACCCGTGGTTGGGTGGAAATTCTAGACGGTTTA
GCCTTGGGCGAAAACGTGGTGATCCGTGGCTTATTGAAAGTCCACCCTGGCGATAAAGTGCAAACGGAGTTCGCGGAAAA
GTTTAGTTATCTTGCTGATACGAGCGCGGAGCCAAGTGTATGA

Upstream 100 bases:

>100_bases
GCTATTGGCGTAATTTGTAAGAAAAAGTAAAACGTATTGATGCGATGATGTGAGTGAGTAAACTAGCCGTCATTAATGCG
AGTCATCCCTTGGAAGCCCG

Downstream 100 bases:

>100_bases
TCCTCACTGATCTCTCGGTAAAACGTCCCGTATTTGCCTCAGTGATCAGCTTGCTGCTGGTCGCTTTCGGGCTTGTCTCC
TTTGATAAGCTGCCCCTGCG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MKKIILIIALLAAAWFGYQAMQPQEIATAQMKLMPNVVIATAAMEPIRDEVEAIGTNKAAESVTITPKVTDMVIALKFDD
GDIVKKGDLLVQLQNAEQIAKVKAAQVKVSDNQREFNRISSLVTSRTVAELERDRLQTLIDTTRAELEQAQASLNDRSIL
APFNGRLGLRQISVGSLVSPGTAITTLDDISKIKLDFSVPERFIQDLAPGKKVEAKAVAFPDFTFKGVVTSIDSRVNPTT
RTVIVRAEIPNPELRLLPGMLMKVKLIKRSREALMLPESAIIPIQNDHFVYSVNADNVIERKQVTIGIRTRGWVEILDGL
ALGENVVIRGLLKVHPGDKVQTEFAEKFSYLADTSAEPSV

Sequences:

>Translated_360_residues
MKKIILIIALLAAAWFGYQAMQPQEIATAQMKLMPNVVIATAAMEPIRDEVEAIGTNKAAESVTITPKVTDMVIALKFDD
GDIVKKGDLLVQLQNAEQIAKVKAAQVKVSDNQREFNRISSLVTSRTVAELERDRLQTLIDTTRAELEQAQASLNDRSIL
APFNGRLGLRQISVGSLVSPGTAITTLDDISKIKLDFSVPERFIQDLAPGKKVEAKAVAFPDFTFKGVVTSIDSRVNPTT
RTVIVRAEIPNPELRLLPGMLMKVKLIKRSREALMLPESAIIPIQNDHFVYSVNADNVIERKQVTIGIRTRGWVEILDGL
ALGENVVIRGLLKVHPGDKVQTEFAEKFSYLADTSAEPSV
>Mature_360_residues
MKKIILIIALLAAAWFGYQAMQPQEIATAQMKLMPNVVIATAAMEPIRDEVEAIGTNKAAESVTITPKVTDMVIALKFDD
GDIVKKGDLLVQLQNAEQIAKVKAAQVKVSDNQREFNRISSLVTSRTVAELERDRLQTLIDTTRAELEQAQASLNDRSIL
APFNGRLGLRQISVGSLVSPGTAITTLDDISKIKLDFSVPERFIQDLAPGKKVEAKAVAFPDFTFKGVVTSIDSRVNPTT
RTVIVRAEIPNPELRLLPGMLMKVKLIKRSREALMLPESAIIPIQNDHFVYSVNADNVIERKQVTIGIRTRGWVEILDGL
ALGENVVIRGLLKVHPGDKVQTEFAEKFSYLADTSAEPSV

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=331, Percent_Identity=29.9093655589124, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1786668, Length=365, Percent_Identity=27.1232876712329, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789929, Length=374, Percent_Identity=25.9358288770053, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789665, Length=343, Percent_Identity=24.198250728863, Blast_Score=85, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39592; Mature: 39592

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIILIIALLAAAWFGYQAMQPQEIATAQMKLMPNVVIATAAMEPIRDEVEAIGTNKAA
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCC
ESVTITPKVTDMVIALKFDDGDIVKKGDLLVQLQNAEQIAKVKAAQVKVSDNQREFNRIS
CEEEECCCEEEEEEEEEECCCCEEECCCEEEEECCHHHHHHHHHEEEEECCCHHHHHHHH
SLVTSRTVAELERDRLQTLIDTTRAELEQAQASLNDRSILAPFNGRLGLRQISVGSLVSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCCCCC
GTAITTLDDISKIKLDFSVPERFIQDLAPGKKVEAKAVAFPDFTFKGVVTSIDSRVNPTT
CCEEEEHHCHHEEEEECCCHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCE
RTVIVRAEIPNPELRLLPGMLMKVKLIKRSREALMLPESAIIPIQNDHFVYSVNADNVIE
EEEEEEEECCCCCHHHHHHHHHHHHHHHHCHHHEECCCCEEEEECCCCEEEEECCCCCEE
RKQVTIGIRTRGWVEILDGLALGENVVIRGLLKVHPGDKVQTEFAEKFSYLADTSAEPSV
CEEEEEEECCCHHHHHHHHHHCCCHHEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKKIILIIALLAAAWFGYQAMQPQEIATAQMKLMPNVVIATAAMEPIRDEVEAIGTNKAA
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCC
ESVTITPKVTDMVIALKFDDGDIVKKGDLLVQLQNAEQIAKVKAAQVKVSDNQREFNRIS
CEEEECCCEEEEEEEEEECCCCEEECCCEEEEECCHHHHHHHHHEEEEECCCHHHHHHHH
SLVTSRTVAELERDRLQTLIDTTRAELEQAQASLNDRSILAPFNGRLGLRQISVGSLVSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCCCCC
GTAITTLDDISKIKLDFSVPERFIQDLAPGKKVEAKAVAFPDFTFKGVVTSIDSRVNPTT
CCEEEEHHCHHEEEEECCCHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCE
RTVIVRAEIPNPELRLLPGMLMKVKLIKRSREALMLPESAIIPIQNDHFVYSVNADNVIE
EEEEEEEECCCCCHHHHHHHHHHHHHHHHCHHHEECCCCEEEEECCCCEEEEECCCCCEE
RKQVTIGIRTRGWVEILDGLALGENVVIRGLLKVHPGDKVQTEFAEKFSYLADTSAEPSV
CEEEEEEECCCHHHHHHHHHHCCCHHEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA