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The map label for this gene is htpG [H]

Identifier: 160875775

GI number: 160875775

Start: 3157235

End: 3159148

Strand: Reverse

Name: htpG [H]

Synonym: Sbal195_2663

Alternate gene names: 160875775

Gene position: 3159148-3157235 (Counterclockwise)

Preceding gene: 160875776

Following gene: 160875774

Centisome position: 59.08

GC content: 48.07

Gene sequence:

>1914_bases
ATGTCACAACAAGAAACTCATGGTTTTCAAACAGAAGTCAAACAGCTGTTGCATTTGATGATCCATTCTTTGTATTCCAA
CAAAGAAATTTTCTTGCGTGAACTGGTCTCCAACGCTGCGGATGCAGCGGACAAGCTGCGTTATCTGGCGTTGACCAATG
ACGCTCTGTATGAAGGCGACGGTGAACTGCGAGTCCGTATCAGTGCTGATAAAGAAAAAGGCACTGTGACCATCGAAGAC
AACGGCGTGGGTATGACCCGTGACGGCGTGATTGAGCATTTAGGCACAATTGCTAAGTCGGGCACCGCTGATTTCTTTAA
AAATCTATCGGGCGAATCCTCAAAGGATTCACAGTTAATCGGCCAGTTCGGTGTCGGTTTCTATTCAGCCTTTATCGTGG
CCAAGAAAGTCACGGTTCGCACTCGCGCTGCCGGTCATAAGGCCGATGAAGCCGTATTGTGGGAATCAGAAGGCGAGGGT
AACTTCACCGTTGATACCATCACTAAGGCGAGCCGTGGTACTGAAATCACGCTGCACCTGCGTGATGAAGAAAAAGAATT
TGCCGATGATTGGCGCCTGCGCTCGATCATCACTAAATACTCAGATCATATTTCTGTGCCGGTCGAAATGTGGCAAGAGG
GTACGCCAGAAAGTGATGGTGCTGATGGCGAAAAAATTCCTGCGACCGAAGGTCAATGGAAAGTCATGAACAAAGCGACT
GCTTTGTGGATGCGCAGCAAAGCTGACATCAGTGACGAAGAGTATCAAGAGTTTTACAAACACATTTCCCACGATTATAC
CGACGCACTACTGTGGAGTCATAATCGGGTAGAAGGTAAGCAAGAATACACTAACTTATTGTATATTCCTGCCAAAGCGC
CTTGGGATATGTGGAACCGCGACCGTAAGCACGGCTTGAAACTGTTTGTGCAACGTGTGTTCATCATGGATGACGCTGAG
CAATTTATGCCATCTTATCTGCGCTTCGTGCAGGGCTTAATTGACTCAAACGATTTGCCGCTGAACGTATCCCGCGAAAT
TCTGCAGGATAACCATGTGACCAAAGCGATGCGTACTGGTATCACCAAACGTGTGCTTGGCATGCTGGAAAAACTGGCGA
AAGACGATGCGGAAAAATATCAACAGTTCTGGGCTGAATTTGGCCAAGTGTTGAAAGAAGGGCCTGCGGAAGATTTCGCC
AACCGTGAACGTATCGCAGGCTTATTACGTTTTGCCTCGACCCACACGGGCAGTGCTGCGCCGACTGTGTCACTCGATGA
CTACATCAGCCGCATGAAAGAAGGCCAAACTAAGATTTATTATATCGTTGCCGACAGCCATGAAGCCGCCGCTAACAGCC
CACATTTAGAGTTGTTACGTAAGAAAGGCATTGAAGTCTTACTGATGTCAGAGCGTATCGACGAGTGGCTAATCAACCAC
TTAACTGAGTACAAAGAGAAACAACTGCACTCAGTGACCCGCGGTGATTTAGAACTTGGCGAGCTGGAAGATGCCTCTGA
AAAAGAAGCGCAAGAAAAGCTTGAGCAAGAATCGGTAGCTTTAGTTGAACGCATTAAAGCGGCATTAGGCTCGACTGTTG
CTGATGTGAAAGTCACGTCACGCTTAACCGACACCCCAGCCTGTGTAGTGGCGGGTGAAGGCGAAATGTCGACTCAGATG
ATCAAGCTGATGCAAGCTGCCGGTCAACCTGTACCAGAAGTGAAGCCAACATTTGAGATCAACCCAGCGCACCCATTAGT
GTCGCGCTTAAATGATCTTCAAGATGAAGCCGCCTTCGCGGATTGGTCAAATCTGCTGCTGCAACAGGCGCAATTGTCTG
AAAAAGGTAGCCTTGCGGATCCATCGGCCTTTATCAAGCTGATGAACCAAATGTTACTGGCTAACATGAAGTAA

Upstream 100 bases:

>100_bases
CGTTTTAGCCCTTGCCCTTGAAAAGCAAATTTGGAGCCCCATTTAAGTAAACACTAAGCGTTACTTTTACCAAATTACGT
AACAAATAAAGGAAAATTTC

Downstream 100 bases:

>100_bases
ATGACTATCGGGGCCTTCTTTGAACGGCCCCGATATTGTTTCTAGTGTAGGAAGAGTGGTTTGCGCCTAGGGCACTCCAC
TTCCGTGTTGCATCAATTCA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGDGELRVRISADKEKGTVTIED
NGVGMTRDGVIEHLGTIAKSGTADFFKNLSGESSKDSQLIGQFGVGFYSAFIVAKKVTVRTRAAGHKADEAVLWESEGEG
NFTVDTITKASRGTEITLHLRDEEKEFADDWRLRSIITKYSDHISVPVEMWQEGTPESDGADGEKIPATEGQWKVMNKAT
ALWMRSKADISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPAKAPWDMWNRDRKHGLKLFVQRVFIMDDAE
QFMPSYLRFVQGLIDSNDLPLNVSREILQDNHVTKAMRTGITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFA
NRERIAGLLRFASTHTGSAAPTVSLDDYISRMKEGQTKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINH
LTEYKEKQLHSVTRGDLELGELEDASEKEAQEKLEQESVALVERIKAALGSTVADVKVTSRLTDTPACVVAGEGEMSTQM
IKLMQAAGQPVPEVKPTFEINPAHPLVSRLNDLQDEAAFADWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANMK

Sequences:

>Translated_637_residues
MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGDGELRVRISADKEKGTVTIED
NGVGMTRDGVIEHLGTIAKSGTADFFKNLSGESSKDSQLIGQFGVGFYSAFIVAKKVTVRTRAAGHKADEAVLWESEGEG
NFTVDTITKASRGTEITLHLRDEEKEFADDWRLRSIITKYSDHISVPVEMWQEGTPESDGADGEKIPATEGQWKVMNKAT
ALWMRSKADISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPAKAPWDMWNRDRKHGLKLFVQRVFIMDDAE
QFMPSYLRFVQGLIDSNDLPLNVSREILQDNHVTKAMRTGITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFA
NRERIAGLLRFASTHTGSAAPTVSLDDYISRMKEGQTKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINH
LTEYKEKQLHSVTRGDLELGELEDASEKEAQEKLEQESVALVERIKAALGSTVADVKVTSRLTDTPACVVAGEGEMSTQM
IKLMQAAGQPVPEVKPTFEINPAHPLVSRLNDLQDEAAFADWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANMK
>Mature_636_residues
SQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGDGELRVRISADKEKGTVTIEDN
GVGMTRDGVIEHLGTIAKSGTADFFKNLSGESSKDSQLIGQFGVGFYSAFIVAKKVTVRTRAAGHKADEAVLWESEGEGN
FTVDTITKASRGTEITLHLRDEEKEFADDWRLRSIITKYSDHISVPVEMWQEGTPESDGADGEKIPATEGQWKVMNKATA
LWMRSKADISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPAKAPWDMWNRDRKHGLKLFVQRVFIMDDAEQ
FMPSYLRFVQGLIDSNDLPLNVSREILQDNHVTKAMRTGITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFAN
RERIAGLLRFASTHTGSAAPTVSLDDYISRMKEGQTKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINHL
TEYKEKQLHSVTRGDLELGELEDASEKEAQEKLEQESVALVERIKAALGSTVADVKVTSRLTDTPACVVAGEGEMSTQMI
KLMQAAGQPVPEVKPTFEINPAHPLVSRLNDLQDEAAFADWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANMK

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=681, Percent_Identity=37.4449339207048, Blast_Score=421, Evalue=1e-118,
Organism=Homo sapiens, GI4507677, Length=687, Percent_Identity=37.2634643377001, Blast_Score=421, Evalue=1e-118,
Organism=Homo sapiens, GI155722983, Length=643, Percent_Identity=34.8367029548989, Blast_Score=371, Evalue=1e-102,
Organism=Homo sapiens, GI154146191, Length=408, Percent_Identity=37.5, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI153792590, Length=408, Percent_Identity=37.5, Blast_Score=265, Evalue=1e-70,
Organism=Escherichia coli, GI1786679, Length=634, Percent_Identity=68.4542586750789, Blast_Score=886, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=668, Percent_Identity=38.0239520958084, Blast_Score=436, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI17542208, Length=665, Percent_Identity=37.7443609022556, Blast_Score=413, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI115535205, Length=651, Percent_Identity=31.6436251920123, Blast_Score=316, Evalue=3e-86,
Organism=Caenorhabditis elegans, GI115535167, Length=445, Percent_Identity=34.3820224719101, Blast_Score=260, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6323840, Length=680, Percent_Identity=37.0588235294118, Blast_Score=433, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6325016, Length=409, Percent_Identity=37.8973105134474, Blast_Score=278, Evalue=2e-75,
Organism=Drosophila melanogaster, GI17647529, Length=684, Percent_Identity=37.8654970760234, Blast_Score=459, Evalue=1e-129,
Organism=Drosophila melanogaster, GI21357739, Length=680, Percent_Identity=37.3529411764706, Blast_Score=411, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24586016, Length=647, Percent_Identity=33.8485316846986, Blast_Score=360, Evalue=2e-99,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71664; Mature: 71533

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGD
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECC
GELRVRISADKEKGTVTIEDNGVGMTRDGVIEHLGTIAKSGTADFFKNLSGESSKDSQLI
CCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHH
GQFGVGFYSAFIVAKKVTVRTRAAGHKADEAVLWESEGEGNFTVDTITKASRGTEITLHL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEHHHCCCCCEEEEEE
RDEEKEFADDWRLRSIITKYSDHISVPVEMWQEGTPESDGADGEKIPATEGQWKVMNKAT
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
ALWMRSKADISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPAKAPWDMWNR
HHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHCCEEEECCCCCHHHHCC
DRKHGLKLFVQRVFIMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNHVTKAMRTG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHH
ITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFANRERIAGLLRFASTHTGSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PTVSLDDYISRMKEGQTKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINH
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHH
LTEYKEKQLHSVTRGDLELGELEDASEKEAQEKLEQESVALVERIKAALGSTVADVKVTS
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RLTDTPACVVAGEGEMSTQMIKLMQAAGQPVPEVKPTFEINPAHPLVSRLNDLQDEAAFA
HCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHH
DWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANMK
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGD
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECC
GELRVRISADKEKGTVTIEDNGVGMTRDGVIEHLGTIAKSGTADFFKNLSGESSKDSQLI
CCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHH
GQFGVGFYSAFIVAKKVTVRTRAAGHKADEAVLWESEGEGNFTVDTITKASRGTEITLHL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEHHHCCCCCEEEEEE
RDEEKEFADDWRLRSIITKYSDHISVPVEMWQEGTPESDGADGEKIPATEGQWKVMNKAT
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
ALWMRSKADISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPAKAPWDMWNR
HHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHCCEEEECCCCCHHHHCC
DRKHGLKLFVQRVFIMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNHVTKAMRTG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHH
ITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFANRERIAGLLRFASTHTGSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PTVSLDDYISRMKEGQTKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINH
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHH
LTEYKEKQLHSVTRGDLELGELEDASEKEAQEKLEQESVALVERIKAALGSTVADVKVTS
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RLTDTPACVVAGEGEMSTQMIKLMQAAGQPVPEVKPTFEINPAHPLVSRLNDLQDEAAFA
HCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHH
DWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANMK
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA