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The map label for this gene is hscB [H]

Identifier: 160875611

GI number: 160875611

Start: 2951518

End: 2952042

Strand: Reverse

Name: hscB [H]

Synonym: Sbal195_2499

Alternate gene names: 160875611

Gene position: 2952042-2951518 (Counterclockwise)

Preceding gene: 160875612

Following gene: 160875610

Centisome position: 55.21

GC content: 47.24

Gene sequence:

>525_bases
ATGAATTATTTCGAGCTGTTTAAATTTCCCCCTGCCTTCGATATTGATACCGCCTTACTTGCAGAACGCTATCGCGAACT
GCAAAGGGCGGTTCATCCCGATAAATTTGCCAATGATACTGAGCAGCAAAAACTGCTGTCGGTGCAGCGCACGGCGCAAG
TCAATGATGGTTTTCAAACCTTAAAAGATCCCATTCGCCGCGCCGAGCATATGCTGTCGCTGCGTGGCATTGAATTAAGC
CATGAAACCACCACAGTGAAAGATACTGGCTTCTTGATGCAGCAAATGGAATGGCGTGAGGCGTTGGAAGACATACGCGA
TAGTGCCGATCCTCAAGCGAGTATTGACGAGCTATATCAATCGTTTGCAGAGTACCGCGAGCAACTCACTCAGCAATTGA
CTCAACTGTTAACCAGTGAGCAGGCTGAAGATGCATTGTTAGCGGCGGATCAAGTTCGCAAACTCAAATTTATGGCAAAA
TTACACGACGAGTTGACCAGAGTCGAAGACGCTCTGTTAGATTGA

Upstream 100 bases:

>100_bases
AAAGAAGGGCTGAATGAAGGCTTCCAATTTAACAATCCTAACGCAAAAGGTGAGTGTGGTTGCGGTGAGAGTTTCACTGT
TTAACCGCTAAAGTTGACGC

Downstream 100 bases:

>100_bases
TTTCCGTGTTTATGTTACTTTGCTGACTCAAGCACGCTTGAGTTGGCATTACTAAGTTGGATATATATGGCCCTTTTGCA
GATAGCTGAGCCCGGTCAAA

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MNYFELFKFPPAFDIDTALLAERYRELQRAVHPDKFANDTEQQKLLSVQRTAQVNDGFQTLKDPIRRAEHMLSLRGIELS
HETTTVKDTGFLMQQMEWREALEDIRDSADPQASIDELYQSFAEYREQLTQQLTQLLTSEQAEDALLAADQVRKLKFMAK
LHDELTRVEDALLD

Sequences:

>Translated_174_residues
MNYFELFKFPPAFDIDTALLAERYRELQRAVHPDKFANDTEQQKLLSVQRTAQVNDGFQTLKDPIRRAEHMLSLRGIELS
HETTTVKDTGFLMQQMEWREALEDIRDSADPQASIDELYQSFAEYREQLTQQLTQLLTSEQAEDALLAADQVRKLKFMAK
LHDELTRVEDALLD
>Mature_174_residues
MNYFELFKFPPAFDIDTALLAERYRELQRAVHPDKFANDTEQQKLLSVQRTAQVNDGFQTLKDPIRRAEHMLSLRGIELS
HETTTVKDTGFLMQQMEWREALEDIRDSADPQASIDELYQSFAEYREQLTQQLTQLLTSEQAEDALLAADQVRKLKFMAK
LHDELTRVEDALLD

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=164, Percent_Identity=28.6585365853659, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1788876, Length=177, Percent_Identity=40.6779661016949, Blast_Score=127, Evalue=4e-31,
Organism=Drosophila melanogaster, GI161084223, Length=173, Percent_Identity=26.5895953757225, Blast_Score=80, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 20279; Mature: 20279

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYFELFKFPPAFDIDTALLAERYRELQRAVHPDKFANDTEQQKLLSVQRTAQVNDGFQT
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCHHHH
LKDPIRRAEHMLSLRGIELSHETTTVKDTGFLMQQMEWREALEDIRDSADPQASIDELYQ
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SFAEYREQLTQQLTQLLTSEQAEDALLAADQVRKLKFMAKLHDELTRVEDALLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYFELFKFPPAFDIDTALLAERYRELQRAVHPDKFANDTEQQKLLSVQRTAQVNDGFQT
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCHHHH
LKDPIRRAEHMLSLRGIELSHETTTVKDTGFLMQQMEWREALEDIRDSADPQASIDELYQ
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SFAEYREQLTQQLTQLLTSEQAEDALLAADQVRKLKFMAKLHDELTRVEDALLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA