Click here to switch to the map view.

The map label for this gene is ychM [C]

Identifier: 160875596

GI number: 160875596

Start: 2935300

End: 2937057

Strand: Reverse

Name: ychM [C]

Synonym: Sbal195_2484

Alternate gene names: 160875596

Gene position: 2937057-2935300 (Counterclockwise)

Preceding gene: 160875597

Following gene: 160875593

Centisome position: 54.93

GC content: 49.66

Gene sequence:

>1758_bases
GTGAAGTTCCCTAGTTTGATTTCGTTTATGCCGGGATTGGCGCAATTATTACAATATGAAAAGCAATGGCTTAGGGATGA
TGTGCGCGCAGGCTTGTCCGTTGCCGCCGTGGCACTCCCTGTTGCCATTGCCTATGCCCAGCTCACTGGCGTCAATGCTG
CTGTGGGTTTGTACTCCTGCGTTTTGCCTATGCTGGTATACGCGCTATTTGGCACCTCAAAGCAATTAATCGTGGGTCCA
GATGCGGCGACCTGCGCCGTTATCGCCGCCGTTGTTACGCCCCTTGCTGCGGGCGATAGCATGAAGCATTGGCAGTTAGT
CATGACCATGACGGCCATGACAGGCTTTTGGTGCTTGATCGCGAGCCGTTTTAAGCTGGGTGTGCTCGCTGACTTTCTGT
CAAAGCCGATTTTGATGGGATTGCTGAACGGGGTCGCGATCACCATTATCGTCGGACAATTCTCGAAGATTTTTGGTTTT
ACCTTCGACGAGCGCTATTTAATCGAACGCCTCAGCGGCGCCCCTTCTTATTTATCAAAAACCCATTGGCCGACCTTGAC
TATGGGGATTGTGACGCTCGCGACCTATGCCTTAGTGAAACGGTTTCGTCCCCAATGGCCCGCATCTATGTGCGCGATGG
CGATGGCGGCGTTTCTTGTTTGGGTATTTAACCTGACGAGCTTTGACATTAGCGTTGTCGGAGAGGTGACTTCAGGACTA
CCTTCATTCCAAGCACCGGCTTTTGATTTGGGGATCGCCCGTGAGTTGGTGGTGCCTGCGCTCAACTTAGCCATGGTGAG
CTTTGTGAGCATGATGCTGACGGCCCGAAGTTTTGCGGCAAAAAATGGTTATGATATAGATGCAGATAAAGAATTCAGGG
CATTAGGTTTAGCCAATATTGCATCTGCCATCTCCCAAGGGTTTGCGGTGAGCGGCGCCGATTCCCGAACTGCGGTAAAC
GATGCCAATGGCGGCAAGAGCCAGTTAGTGTCCATCATAGCTGCGGTATTGATTGGCGTTGTCGCGCTGTTTTTTACTGC
GCCGTTGAAGTACATCCCTAGCGCAGCATTAGGGGTGGTATTGGTGATTGCCTCTATTTCGCTTATCGATCTTAAGTCGT
TGTGGAATCTGCGTGTGCGCGATAAATCAGCTTTCTTGCTTGCGTGTATTACCTTGTTCTCAGTGCTGTTTATTGGGGTG
ATTCCTGGGATCACTTTGGCCGTGTTACTGGGGTTATTCCAGTTCCTTGCTACGGTAATGCGCCCCACGGATCAAGTGCT
TGGTTTAGATCATAAGGGCGTTATCCGCAGCGTCGATGATTCGGGTAAAGCTAAATCTGTGCCTGGCGTGTTTATGTATC
GCTTTAATTCGCCGTTAACTTACTTTAATGCGACGTATTTTAAGCGCCGTTTACTGGAAAAGTTTATTCGGGAATCTGAG
CCGGTCGATTGCATCATTATTGATGCCGTGCCTTGTTTTACCCATTTAGATTTAAGCGTGATGGCTATGTTGGCAGATTT
ACATCAATTGCTTAAAAAGCGTGGAGTACGCTTGGTGCTTGCGGGGCGTAAACGACAGATGCTGAGTTGGTTCGAGCAAG
CGGGCATGCAGACAGGGGAAGGCGGTATTCTGATACGGCCAGATTTGTATCTCGCCCTTAAAATGAATCAAAGCTATAAA
CAAGCCTTGGCTGAAGGGCAAGCACCTGTGATCCAAAAAGTCCCCGATGATGCTGTGCTGTTGCATAGCCATTTATAG

Upstream 100 bases:

>100_bases
ACTATTGCTGGCTTTTAGGTAATGACCTTTTCGCTGAATATTTTCAGTCTCGGTTATACTGATTAGTGCTTATCTTGATG
GTGTGTATGGAGGTTGCCGA

Downstream 100 bases:

>100_bases
CGAATGATTTAAATTTCAAGGTTTTGTAAAAGAGGGGTCATTAAAATAGCGCAGCCTAAGCTTGCGCTATTTTTTGCGTG
TTTCAGTACTTTTAAGTATT

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MKFPSLISFMPGLAQLLQYEKQWLRDDVRAGLSVAAVALPVAIAYAQLTGVNAAVGLYSCVLPMLVYALFGTSKQLIVGP
DAATCAVIAAVVTPLAAGDSMKHWQLVMTMTAMTGFWCLIASRFKLGVLADFLSKPILMGLLNGVAITIIVGQFSKIFGF
TFDERYLIERLSGAPSYLSKTHWPTLTMGIVTLATYALVKRFRPQWPASMCAMAMAAFLVWVFNLTSFDISVVGEVTSGL
PSFQAPAFDLGIARELVVPALNLAMVSFVSMMLTARSFAAKNGYDIDADKEFRALGLANIASAISQGFAVSGADSRTAVN
DANGGKSQLVSIIAAVLIGVVALFFTAPLKYIPSAALGVVLVIASISLIDLKSLWNLRVRDKSAFLLACITLFSVLFIGV
IPGITLAVLLGLFQFLATVMRPTDQVLGLDHKGVIRSVDDSGKAKSVPGVFMYRFNSPLTYFNATYFKRRLLEKFIRESE
PVDCIIIDAVPCFTHLDLSVMAMLADLHQLLKKRGVRLVLAGRKRQMLSWFEQAGMQTGEGGILIRPDLYLALKMNQSYK
QALAEGQAPVIQKVPDDAVLLHSHL

Sequences:

>Translated_585_residues
MKFPSLISFMPGLAQLLQYEKQWLRDDVRAGLSVAAVALPVAIAYAQLTGVNAAVGLYSCVLPMLVYALFGTSKQLIVGP
DAATCAVIAAVVTPLAAGDSMKHWQLVMTMTAMTGFWCLIASRFKLGVLADFLSKPILMGLLNGVAITIIVGQFSKIFGF
TFDERYLIERLSGAPSYLSKTHWPTLTMGIVTLATYALVKRFRPQWPASMCAMAMAAFLVWVFNLTSFDISVVGEVTSGL
PSFQAPAFDLGIARELVVPALNLAMVSFVSMMLTARSFAAKNGYDIDADKEFRALGLANIASAISQGFAVSGADSRTAVN
DANGGKSQLVSIIAAVLIGVVALFFTAPLKYIPSAALGVVLVIASISLIDLKSLWNLRVRDKSAFLLACITLFSVLFIGV
IPGITLAVLLGLFQFLATVMRPTDQVLGLDHKGVIRSVDDSGKAKSVPGVFMYRFNSPLTYFNATYFKRRLLEKFIRESE
PVDCIIIDAVPCFTHLDLSVMAMLADLHQLLKKRGVRLVLAGRKRQMLSWFEQAGMQTGEGGILIRPDLYLALKMNQSYK
QALAEGQAPVIQKVPDDAVLLHSHL
>Mature_585_residues
MKFPSLISFMPGLAQLLQYEKQWLRDDVRAGLSVAAVALPVAIAYAQLTGVNAAVGLYSCVLPMLVYALFGTSKQLIVGP
DAATCAVIAAVVTPLAAGDSMKHWQLVMTMTAMTGFWCLIASRFKLGVLADFLSKPILMGLLNGVAITIIVGQFSKIFGF
TFDERYLIERLSGAPSYLSKTHWPTLTMGIVTLATYALVKRFRPQWPASMCAMAMAAFLVWVFNLTSFDISVVGEVTSGL
PSFQAPAFDLGIARELVVPALNLAMVSFVSMMLTARSFAAKNGYDIDADKEFRALGLANIASAISQGFAVSGADSRTAVN
DANGGKSQLVSIIAAVLIGVVALFFTAPLKYIPSAALGVVLVIASISLIDLKSLWNLRVRDKSAFLLACITLFSVLFIGV
IPGITLAVLLGLFQFLATVMRPTDQVLGLDHKGVIRSVDDSGKAKSVPGVFMYRFNSPLTYFNATYFKRRLLEKFIRESE
PVDCIIIDAVPCFTHLDLSVMAMLADLHQLLKKRGVRLVLAGRKRQMLSWFEQAGMQTGEGGILIRPDLYLALKMNQSYK
QALAEGQAPVIQKVPDDAVLLHSHL

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=509, Percent_Identity=26.3261296660118, Blast_Score=156, Evalue=6e-38,
Organism=Homo sapiens, GI39752683, Length=509, Percent_Identity=26.3261296660118, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI262206105, Length=563, Percent_Identity=26.2877442273535, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI262206075, Length=563, Percent_Identity=26.2877442273535, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI262206069, Length=563, Percent_Identity=26.2877442273535, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI262206063, Length=563, Percent_Identity=26.2877442273535, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI94721257, Length=499, Percent_Identity=26.0521042084168, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI94721259, Length=499, Percent_Identity=26.0521042084168, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI94721255, Length=499, Percent_Identity=26.0521042084168, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI94721253, Length=499, Percent_Identity=26.0521042084168, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI269784651, Length=505, Percent_Identity=25.5445544554455, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI4557535, Length=519, Percent_Identity=26.5895953757225, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI4505697, Length=510, Percent_Identity=25.8823529411765, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI45827802, Length=448, Percent_Identity=26.7857142857143, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI100913030, Length=529, Percent_Identity=23.6294896030246, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI16418413, Length=509, Percent_Identity=22.7897838899804, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI217272867, Length=509, Percent_Identity=22.7897838899804, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI16418457, Length=523, Percent_Identity=25.0478011472275, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI301601599, Length=523, Percent_Identity=25.0478011472275, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI47131207, Length=521, Percent_Identity=24.9520153550864, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI20336272, Length=521, Percent_Identity=24.9520153550864, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI20336282, Length=579, Percent_Identity=22.1070811744387, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI16306483, Length=579, Percent_Identity=22.1070811744387, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI301601602, Length=290, Percent_Identity=25.5172413793103, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI65506789, Length=371, Percent_Identity=26.1455525606469, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI45827804, Length=271, Percent_Identity=25.0922509225092, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI87081859, Length=435, Percent_Identity=22.7586206896552, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI86565215, Length=501, Percent_Identity=24.750499001996, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI86564196, Length=523, Percent_Identity=24.4741873804971, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17551690, Length=578, Percent_Identity=22.8373702422145, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17566848, Length=568, Percent_Identity=24.2957746478873, Blast_Score=122, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17562578, Length=601, Percent_Identity=22.1297836938436, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI193203292, Length=507, Percent_Identity=22.879684418146, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI86564876, Length=386, Percent_Identity=21.5025906735751, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI86565209, Length=244, Percent_Identity=25, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86565211, Length=244, Percent_Identity=25, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6325260, Length=583, Percent_Identity=22.8130360205832, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323121, Length=470, Percent_Identity=23.1914893617021, Blast_Score=98, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6319771, Length=471, Percent_Identity=24.8407643312102, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21358229, Length=461, Percent_Identity=27.3318872017354, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24649801, Length=566, Percent_Identity=26.3250883392226, Blast_Score=136, Evalue=5e-32,
Organism=Drosophila melanogaster, GI85815873, Length=607, Percent_Identity=25.0411861614498, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24666186, Length=671, Percent_Identity=23.0998509687034, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI19922482, Length=420, Percent_Identity=26.6666666666667, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24647160, Length=440, Percent_Identity=24.3181818181818, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI21355087, Length=440, Percent_Identity=24.3181818181818, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24651449, Length=588, Percent_Identity=23.1292517006803, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21358633, Length=459, Percent_Identity=23.5294117647059, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24663084, Length=444, Percent_Identity=25.6756756756757, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357695, Length=444, Percent_Identity=25.6756756756757, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 63400; Mature: 63400

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCEEECCCEEEEEECCHHHHHHHHCCCCCHHHHCCCCHHHHCCCC
>Mature Secondary Structure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CCEEECCCEEEEEECCHHHHHHHHCCCCCHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]