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The map label for this gene is serC [H]

Identifier: 160875515

GI number: 160875515

Start: 2835508

End: 2836599

Strand: Reverse

Name: serC [H]

Synonym: Sbal195_2403

Alternate gene names: 160875515

Gene position: 2836599-2835508 (Counterclockwise)

Preceding gene: 160875516

Following gene: 160875514

Centisome position: 53.05

GC content: 46.89

Gene sequence:

>1092_bases
GTGAGCGCGATTTATAATTTCTGTGCTGGACCTGCAATGTTACCCGCAGCGGTAATGAAAAAAGCACAACAGGAATTACT
TGATTGGAATGGCCAAGGCGTTTCCGTGATGGAAATCAGCCACCGAAGTAAAGAGTTCATCGCGCTGACCGAGCAAGCCG
AGTCCGATTTACGTGAACTGATGCAGATCCCTGCAAATTACCATGTGCTATTTATGCACGGCGGTGGTCGCGGACAGTTC
TCTGCTGTTGTGAATAATTTTCTCGGCGAGCAGGGTAAAGCCCTGTATTTAGTCAGTGGCCAATGGTCATCTGCCGCGTT
AGCAGAAGCGCAGAAACTGGCGGGTGAAGCACAGATTGATAGTCTGAATATTGTTGAAAAACACAATGGACTCAATGCGG
TTGTCTTACCTGACTTACATAAAATCGATGCCGATTATCGCTATGTTCACTACTGTCCCAATGAGACAGTAGATGGTATC
GAAATTTTTGACGAATTAGACTCACCTTGGCCAATTGTTGCCGATTTATCATCAACAATCATGTCCCGTGAAATCGACGT
CAGCCGCTACGGCTTGATTTACGCCGGTGCGCAAAAGAACATAGGTCCATCGGGTCTGTCGATAGTGATAGTACGCGATG
ACATGTTAAAACTGCCGAGTTTACCGCAGTCGTCCATCATGGACTATCGTCTAGCCGTCGAGCATGATTCTATGTTCAAC
ACGCCACCAACCTTTGCTTGGTACCTTGCCGCTGAAGTCTTTGCTTGGCTGAAATCGACTGGCGGTATTTCGAGTATTGC
GAAAATTAATCAACAAAAAGCGCAGATGTTGTATCAATGCATTGATGGTAATGCTTTCTACCGTAATGGTGTTGTTGCAG
CGAATCGCTCACAAATGAACGTGACCTTCCAGTTAGTCAACGAAGCGCTCGATGGTGAGTTCTTAAAGCAAGCACAAATT
GCTGGACTCGTGGCCTTAAAGGGCCATCGTATCGTAGGCGGCATGCGCGCTAGCCTTTACAATGCGATGCCACTCGATGG
CATAGTTGCCTTGGTCAAGTTTATGAACGAGTTTGCGGCTAAACATAGCTAG

Upstream 100 bases:

>100_bases
CGTTTTTTTAATGGCATTGATTGTTGGTAGCATTATTCGTTTTAGAATGGTTTCGTATTTATCAATACATACATCATGGT
TGGGATTAAGGAGAGTGTCA

Downstream 100 bases:

>100_bases
GCTTAGCTATATAGTCACTCACTAGCTTGCGGCGCTTAGCGCCTAGGTTTTGCTGCCTGCACATAAACGTTATGTTTATT
GAATGTTTATCATCAGCTAG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSAIYNFCAGPAMLPAAVMKKAQQELLDWNGQGVSVMEISHRSKEFIALTEQAESDLRELMQIPANYHVLFMHGGGRGQF
SAVVNNFLGEQGKALYLVSGQWSSAALAEAQKLAGEAQIDSLNIVEKHNGLNAVVLPDLHKIDADYRYVHYCPNETVDGI
EIFDELDSPWPIVADLSSTIMSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLPQSSIMDYRLAVEHDSMFN
TPPTFAWYLAAEVFAWLKSTGGISSIAKINQQKAQMLYQCIDGNAFYRNGVVAANRSQMNVTFQLVNEALDGEFLKQAQI
AGLVALKGHRIVGGMRASLYNAMPLDGIVALVKFMNEFAAKHS

Sequences:

>Translated_363_residues
MSAIYNFCAGPAMLPAAVMKKAQQELLDWNGQGVSVMEISHRSKEFIALTEQAESDLRELMQIPANYHVLFMHGGGRGQF
SAVVNNFLGEQGKALYLVSGQWSSAALAEAQKLAGEAQIDSLNIVEKHNGLNAVVLPDLHKIDADYRYVHYCPNETVDGI
EIFDELDSPWPIVADLSSTIMSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLPQSSIMDYRLAVEHDSMFN
TPPTFAWYLAAEVFAWLKSTGGISSIAKINQQKAQMLYQCIDGNAFYRNGVVAANRSQMNVTFQLVNEALDGEFLKQAQI
AGLVALKGHRIVGGMRASLYNAMPLDGIVALVKFMNEFAAKHS
>Mature_362_residues
SAIYNFCAGPAMLPAAVMKKAQQELLDWNGQGVSVMEISHRSKEFIALTEQAESDLRELMQIPANYHVLFMHGGGRGQFS
AVVNNFLGEQGKALYLVSGQWSSAALAEAQKLAGEAQIDSLNIVEKHNGLNAVVLPDLHKIDADYRYVHYCPNETVDGIE
IFDELDSPWPIVADLSSTIMSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLPQSSIMDYRLAVEHDSMFNT
PPTFAWYLAAEVFAWLKSTGGISSIAKINQQKAQMLYQCIDGNAFYRNGVVAANRSQMNVTFQLVNEALDGEFLKQAQIA
GLVALKGHRIVGGMRASLYNAMPLDGIVALVKFMNEFAAKHS

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=369, Percent_Identity=41.1924119241192, Blast_Score=287, Evalue=1e-77,
Organism=Homo sapiens, GI10863955, Length=365, Percent_Identity=36.7123287671233, Blast_Score=239, Evalue=3e-63,
Organism=Escherichia coli, GI1787136, Length=364, Percent_Identity=56.8681318681319, Blast_Score=420, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI17506897, Length=367, Percent_Identity=42.5068119891008, Blast_Score=278, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6324758, Length=389, Percent_Identity=39.8457583547558, Blast_Score=252, Evalue=6e-68,
Organism=Drosophila melanogaster, GI21356589, Length=364, Percent_Identity=43.6813186813187, Blast_Score=306, Evalue=1e-83,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39853; Mature: 39722

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIYNFCAGPAMLPAAVMKKAQQELLDWNGQGVSVMEISHRSKEFIALTEQAESDLREL
CCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHEEEHHHHHHHHHHH
MQIPANYHVLFMHGGGRGQFSAVVNNFLGEQGKALYLVSGQWSSAALAEAQKLAGEAQID
HHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCC
SLNIVEKHNGLNAVVLPDLHKIDADYRYVHYCPNETVDGIEIFDELDSPWPIVADLSSTI
CEEEEECCCCCCEEECCCHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCHHHHHHHH
MSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLPQSSIMDYRLAVEHDSMFN
HHHCCCHHHCEEEEECCCCCCCCCCEEEEEEECCHHCCCCCCHHHHHHEEEEEECCCCCC
TPPTFAWYLAAEVFAWLKSTGGISSIAKINQQKAQMLYQCIDGNAFYRNGVVAANRSQMN
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCE
VTFQLVNEALDGEFLKQAQIAGLVALKGHRIVGGMRASLYNAMPLDGIVALVKFMNEFAA
EHHHHHHHHHCHHHHHHHHHHHEEEECCCEEECHHHHHHHCCCCHHHHHHHHHHHHHHHH
KHS
CCC
>Mature Secondary Structure 
SAIYNFCAGPAMLPAAVMKKAQQELLDWNGQGVSVMEISHRSKEFIALTEQAESDLREL
CCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHEEEHHHHHHHHHHH
MQIPANYHVLFMHGGGRGQFSAVVNNFLGEQGKALYLVSGQWSSAALAEAQKLAGEAQID
HHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCC
SLNIVEKHNGLNAVVLPDLHKIDADYRYVHYCPNETVDGIEIFDELDSPWPIVADLSSTI
CEEEEECCCCCCEEECCCHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCHHHHHHHH
MSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLPQSSIMDYRLAVEHDSMFN
HHHCCCHHHCEEEEECCCCCCCCCCEEEEEEECCHHCCCCCCHHHHHHEEEEEECCCCCC
TPPTFAWYLAAEVFAWLKSTGGISSIAKINQQKAQMLYQCIDGNAFYRNGVVAANRSQMN
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCE
VTFQLVNEALDGEFLKQAQIAGLVALKGHRIVGGMRASLYNAMPLDGIVALVKFMNEFAA
EHHHHHHHHHCHHHHHHHHHHHEEEECCCEEECHHHHHHHCCCCHHHHHHHHHHHHHHHH
KHS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]