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The map label for this gene is lpxK [H]

Identifier: 160874823

GI number: 160874823

Start: 2054416

End: 2055435

Strand: Direct

Name: lpxK [H]

Synonym: Sbal195_1706

Alternate gene names: 160874823

Gene position: 2054416-2055435 (Clockwise)

Preceding gene: 160874822

Following gene: 160874824

Centisome position: 38.42

GC content: 51.37

Gene sequence:

>1020_bases
ATGCAGGCCTTAGTGAATAAAATTTGGTATCAGGGTCATCCACTGCGATGGCTCTTGTTACCTTTATCTTGGCTATTCGC
GGTTATCACTTATGTGCGCCGCGCCTTGTTTCGCCTCGGGATCAAATCACAAACGGCAATGCCTGTGCCTGTCATCGTTG
TCGGTAATATTACCGTCGGCGGCAGCGGTAAGACGCCAACCGTGATTTATCTGATTGAGCTACTGCGCCAGCATGGGTTT
ACACCCGGCGTGATCAGTCGAGGTTACGGCGTTGATATTCAAGGTGTTAGAACGGTTAATTTAGGGGCGAGTGCAGTTGA
GGTCGGTGATGAACCGGCCATGATAGTGGCGCGCACTCAAGTGCCTATGGTAGTTGGCGCTAAACGCGTCGATGCGGCCA
ATGCGCTTATTGCCGAGTTTGGTGTCGATGTTATCATCTGCGACGATGGACTGCAGCACTATGCGCTGGGGCGCGATATC
GAGCTGGTGGTGATTGATGGTCAACGCGGTTTAGGCAATGGCTTGTTGTTACCGGCAGGTCCGCTGCGTGAAGGCGCGTG
GCGTCTCGATGCCGTGGATTTTATCGTCAATAATGGTGGCCCAGCAGCAAAAGGGCAGTTCGAAATGCAACTGGCCCCTA
CTGAAGTGAAACCCGTTAAATGCGATTTGACCTCAGGTGAGTACAGTTTCGATAAATCTCAGCCGCTGGTTGCGATGGCG
GGTATTGGTAACCCTGCGCGTTTCTTTGAATCGCTGCGCGCTCAAGGTTATCAACTGGCGCTATGTCAGGGGTTTGATGA
TCATCAGCCCTACGATAAAACCCAATTACGTGATTTAGCCCAAGACTTGCCGCTATTGATGACAGAAAAAGATGCGGTTA
AATGTCGCGATTTTGCACAAGAGAACTGGTGGTATTTGGCGGTCAATGCCAAGCTATCCCCACAATTTGATGAGCAGCTG
CTCGCGCGTCTTCGCGAGGTGGCTGCAGCTAAACAAGGAAACTTCCATGGCATTCGATAA

Upstream 100 bases:

>100_bases
GGTGGATCAGGGACGTATCGTCGAGCGCGGGACGCACCAATCACTATTGGAATTAAATGGCATGTACGCCAAATTGTACC
AAATGCAATTCGGTAGCTAG

Downstream 100 bases:

>100_bases
AAAATTGTTAGATATAGTGGCTTGCCCTGTGTGTAAGGGAAAACTTGAGTACGATAAAACGACGCAGCAGTTGATTTGTA
AGGCAGATAAGCTGGCCTAT

Product: tetraacyldisaccharide 4'-kinase

Products: NA

Alternate protein names: Lipid A 4'-kinase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MQALVNKIWYQGHPLRWLLLPLSWLFAVITYVRRALFRLGIKSQTAMPVPVIVVGNITVGGSGKTPTVIYLIELLRQHGF
TPGVISRGYGVDIQGVRTVNLGASAVEVGDEPAMIVARTQVPMVVGAKRVDAANALIAEFGVDVIICDDGLQHYALGRDI
ELVVIDGQRGLGNGLLLPAGPLREGAWRLDAVDFIVNNGGPAAKGQFEMQLAPTEVKPVKCDLTSGEYSFDKSQPLVAMA
GIGNPARFFESLRAQGYQLALCQGFDDHQPYDKTQLRDLAQDLPLLMTEKDAVKCRDFAQENWWYLAVNAKLSPQFDEQL
LARLREVAAAKQGNFHGIR

Sequences:

>Translated_339_residues
MQALVNKIWYQGHPLRWLLLPLSWLFAVITYVRRALFRLGIKSQTAMPVPVIVVGNITVGGSGKTPTVIYLIELLRQHGF
TPGVISRGYGVDIQGVRTVNLGASAVEVGDEPAMIVARTQVPMVVGAKRVDAANALIAEFGVDVIICDDGLQHYALGRDI
ELVVIDGQRGLGNGLLLPAGPLREGAWRLDAVDFIVNNGGPAAKGQFEMQLAPTEVKPVKCDLTSGEYSFDKSQPLVAMA
GIGNPARFFESLRAQGYQLALCQGFDDHQPYDKTQLRDLAQDLPLLMTEKDAVKCRDFAQENWWYLAVNAKLSPQFDEQL
LARLREVAAAKQGNFHGIR
>Mature_339_residues
MQALVNKIWYQGHPLRWLLLPLSWLFAVITYVRRALFRLGIKSQTAMPVPVIVVGNITVGGSGKTPTVIYLIELLRQHGF
TPGVISRGYGVDIQGVRTVNLGASAVEVGDEPAMIVARTQVPMVVGAKRVDAANALIAEFGVDVIICDDGLQHYALGRDI
ELVVIDGQRGLGNGLLLPAGPLREGAWRLDAVDFIVNNGGPAAKGQFEMQLAPTEVKPVKCDLTSGEYSFDKSQPLVAMA
GIGNPARFFESLRAQGYQLALCQGFDDHQPYDKTQLRDLAQDLPLLMTEKDAVKCRDFAQENWWYLAVNAKLSPQFDEQL
LARLREVAAAKQGNFHGIR

Specific function: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) [H]

COG id: COG1663

COG function: function code M; Tetraacyldisaccharide-1-P 4'-kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxK family [H]

Homologues:

Organism=Escherichia coli, GI1787144, Length=333, Percent_Identity=44.4444444444444, Blast_Score=270, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003758 [H]

Pfam domain/function: PF02606 LpxK [H]

EC number: =2.7.1.130 [H]

Molecular weight: Translated: 37133; Mature: 37133

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALVNKIWYQGHPLRWLLLPLSWLFAVITYVRRALFRLGIKSQTAMPVPVIVVGNITVG
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEC
GSGKTPTVIYLIELLRQHGFTPGVISRGYGVDIQGVRTVNLGASAVEVGDEPAMIVARTQ
CCCCCCHHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEEEECCCCEEECCCCCEEEEEECC
VPMVVGAKRVDAANALIAEFGVDVIICDDGLQHYALGRDIELVVIDGQRGLGNGLLLPAG
CCEEECCCHHHHHHHHHHHHCCEEEEECCCCHHHHCCCCEEEEEEECCCCCCCCEECCCC
PLREGAWRLDAVDFIVNNGGPAAKGQFEMQLAPTEVKPVKCDLTSGEYSFDKSQPLVAMA
CCCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCEEEEE
GIGNPARFFESLRAQGYQLALCQGFDDHQPYDKTQLRDLAQDLPLLMTEKDAVKCRDFAQ
CCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHCC
ENWWYLAVNAKLSPQFDEQLLARLREVAAAKQGNFHGIR
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQALVNKIWYQGHPLRWLLLPLSWLFAVITYVRRALFRLGIKSQTAMPVPVIVVGNITVG
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEC
GSGKTPTVIYLIELLRQHGFTPGVISRGYGVDIQGVRTVNLGASAVEVGDEPAMIVARTQ
CCCCCCHHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEEEECCCCEEECCCCCEEEEEECC
VPMVVGAKRVDAANALIAEFGVDVIICDDGLQHYALGRDIELVVIDGQRGLGNGLLLPAG
CCEEECCCHHHHHHHHHHHHCCEEEEECCCCHHHHCCCCEEEEEEECCCCCCCCEECCCC
PLREGAWRLDAVDFIVNNGGPAAKGQFEMQLAPTEVKPVKCDLTSGEYSFDKSQPLVAMA
CCCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCEEEEE
GIGNPARFFESLRAQGYQLALCQGFDDHQPYDKTQLRDLAQDLPLLMTEKDAVKCRDFAQ
CCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHCC
ENWWYLAVNAKLSPQFDEQLLARLREVAAAKQGNFHGIR
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA