Click here to switch to the map view.

The map label for this gene is btuB [H]

Identifier: 160874772

GI number: 160874772

Start: 1998898

End: 2001690

Strand: Direct

Name: btuB [H]

Synonym: Sbal195_1655

Alternate gene names: 160874772

Gene position: 1998898-2001690 (Clockwise)

Preceding gene: 160874771

Following gene: 160874773

Centisome position: 37.38

GC content: 40.71

Gene sequence:

>2793_bases
ATGCATAGAAATAATATTTTGACTCACTCGATTCGTACTGCATTAATAAGTGGTGTTGCAGTTGTAGCATTTACAACACC
TGTTGCATTTGCCGCTGAAGATGGTGCAAAAGTAGAACGTATTGAAGTAACTGGGTCACGTATCAAGCGCACAGATATGG
AGTCAGCTAGCCCTGTATTGTCGATGAATCGTGATGAGATTGAAGCGACAGGGATGATAAGTATTGGTGATATTCTTCAA
ACAATCCCTGCTGCAGGATCTGCATTAAATACCGCATTTAACAATGGTGGTAATGGTTCAACTAACATGGACCTTCGTAA
TTTAGGTTCTCAACGTTTGTTGGTTTTGGTAAACGGTAAACGCTGGATATCTTCATTAGGTTCAACAGTAGATTTAAACA
CTATACCTACGTCAGCAATTGAACGTATTGATGTGCTTAAAGATGGCGCTTCTGCAGTTTATGGTTCTGATGCGATTGCT
GGTGTAGTAAACATTATTACTCGTAAGAACTTTGAAGGTGTTGAAGTTTCTGTTTATGGTGGCCAAAACTCAAAATACGA
TGATGGACGTCAGTATACTGCAGATATTACCTTTGGCTCAGTATCCGAGAAAGGTGGCTTATTATTTAATATGAGCCATG
TGACTCAGCAACCAATATGGGCTGGCGATAGGGATATATCAGCTACGGGTTATAGCTCAACGGCAGATAATACTCGTTTG
AAAGTAAAAGGATCCCAGTTTAATCAAGCTAACCAAGATGCTCTTGCGGCTGTCGGGACTGCAAATAGTTCGGGCATTTA
TGATTTTATGTCGAAAGAAGGCACAGGTGTTAACGTTGGTGTTGACCAATTGCGTCCTCGAACTGGCAGTGATGTTTATA
ACTTTGCGCCGGATAACTACTTATCAACGCCGCAGAATCGTAACTCATTCTATGTACAAGGTTTTTATGATATTTCAGAT
GACCTACGGTTTGTGTCTGATTTTATGATGACCAATCGTAAATCATCACAGGAATTAGCGCCAATGCCACTAACACTTGG
TGCTTCATTTGGTGAAGCTGCAAGTCGAGTAGATATTGGAGCAAATAATATTTACAACCCATTTGGCGAAAAGCTTTATG
GTAGTAATGCTCGTGCTGTTGCTAATGGTGAAGCGGCAGGTTATGTACCTTATGCATTACAGCGTCGAATGATAGAGGCG
GGTTCCCGTCAATATAATCAAAATGATACCACGTACCGAGCTATGGTTGGGTTAGAAGGCAACATTGGTGATAATTGGAC
TTGGAGCGCAACATATATTTACGGCCAAAATAACCAAGATATATTAACCACTGGATTGTTAAATTTAACACGTATTAATC
AAGCGCTTGGTGATGATTGTAATGCAGCAAACGGATGTGTAGCTCTTAACTTATTTGGTGGACCGGGAACTATTACTGAA
GATATGGTCGATTACATTACATTTGATAGTGTAAGCCGTTCAGGTTTGACGATGAAAGATTATGCTTTCAATATTTCAGG
GGATTTATTTGATTTACCAGCTGGTGCAGTAGGTATTGCAATAGGTCTAGAGCGACGTGAGGAGTCGGGTTTTGATACTC
CAGACCCATTAACTGTTACTGGTGAATCATCAGGTAACCAACGTGATGCTACCGCTGGTGGTTTCCGTCTAGATGAAGCT
TATACTGAGCTTTCAATTCCTATTTTAGAAAACTTATTGTTAACACCAGCGATTCGCGTATCTGATCATGACGCTTATGG
TAATAGCACTACTGGGAAAGTGGGCTTAGAATTCCGCCCAATGGATGATATGTTGCTTAGGGGTACATGGGCACAAGGAT
ATCGTGCTCCATCTATTTCTGATCTTTATGCTGGTAATGCTGATTCTTATCCAACTTGGACAGACCCATGTAACACTCGT
GATGACAAAGGTAATCCAGTTGATATTTCTGGTAAACCAGGTTGCGCGGCTGTACCAGACGGCTACCGTCAGGCTAATAC
CCAGATCCGGATTTCACAAGTATCTTCTCCTGATTTAAAACCTGAAACTTCTGAGTCCTATACTTTTGGAACGGTTTATA
ATCCATCTTGGCTAGAGGGTGCAGAGCTAACATTAGATTATTATAATATTAAAGTGGAAGATGCTATTGGCCGTTACGGG
CATACTCGAATTGCAACTGAGTGCGCTGATGGCGATAATCAAGCTGCTTGCGGCAATATTGACCGCGATAGCCTAGGCAA
TATTGTTGATTTACGTAACTACTTGCAAAATGCGGGGACTTATGAAGTTGAAGGCGTTGATTTCTTCACTGCTTATCGCT
TCCCTGAGTCATCGTTTGGTACATTTAAAGCGTCTCTAGATCTGGCTTATGTCATCAATAATAAATCTGATGGAGAGGAC
CGTGCAGGTATACAATTTGGGGATGGTGGTTTTCCTAAGTTAAAAGGAAATTTGAATATTGACTGGGTAATGGGTGATTG
GGACGCTCATTGGAAAACTCGATATGTTGGAGCCATGGATAACGATTACGTCGAAACCTACGGTTTTACTGCTGCCAAAA
ATGGTATTACAGAACGATTCGATTCATATATGGTCCACAATGTTTCAGTTGGTTATAACTTTGATAGTTACAATACAAAA
GTTGCAGTGGGTATAAATAACTTATTTGCAAAGGAACCACAGTGGGAAGCTCCAGATAATGGCTTGGCTATTTCTACAAA
TAATTTCTCTGTGACTGAGTATGATGTAAACATGGACAGATTTGTGTATTTGCGTGCAACGACAAAGTTCTAA

Upstream 100 bases:

>100_bases
TTTCGAATATACATTTAATCCAAAAAATGGTGTGTATATAGCCCTATTTAGTAGGGATATAAGAAAAACATAAAACATAA
TTGTCCAGGGAGATTAGGCA

Downstream 100 bases:

>100_bases
TGTTTAATAAATAGTTAAATTTTAAAGGCCGAACTCTTTTTTAATGATAGGGTTCGGCCTTTGTAGCTTAATATGGTTGT
TATTTTGTCAGCCAAAATGA

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 930; Mature: 930

Protein sequence:

>930_residues
MHRNNILTHSIRTALISGVAVVAFTTPVAFAAEDGAKVERIEVTGSRIKRTDMESASPVLSMNRDEIEATGMISIGDILQ
TIPAAGSALNTAFNNGGNGSTNMDLRNLGSQRLLVLVNGKRWISSLGSTVDLNTIPTSAIERIDVLKDGASAVYGSDAIA
GVVNIITRKNFEGVEVSVYGGQNSKYDDGRQYTADITFGSVSEKGGLLFNMSHVTQQPIWAGDRDISATGYSSTADNTRL
KVKGSQFNQANQDALAAVGTANSSGIYDFMSKEGTGVNVGVDQLRPRTGSDVYNFAPDNYLSTPQNRNSFYVQGFYDISD
DLRFVSDFMMTNRKSSQELAPMPLTLGASFGEAASRVDIGANNIYNPFGEKLYGSNARAVANGEAAGYVPYALQRRMIEA
GSRQYNQNDTTYRAMVGLEGNIGDNWTWSATYIYGQNNQDILTTGLLNLTRINQALGDDCNAANGCVALNLFGGPGTITE
DMVDYITFDSVSRSGLTMKDYAFNISGDLFDLPAGAVGIAIGLERREESGFDTPDPLTVTGESSGNQRDATAGGFRLDEA
YTELSIPILENLLLTPAIRVSDHDAYGNSTTGKVGLEFRPMDDMLLRGTWAQGYRAPSISDLYAGNADSYPTWTDPCNTR
DDKGNPVDISGKPGCAAVPDGYRQANTQIRISQVSSPDLKPETSESYTFGTVYNPSWLEGAELTLDYYNIKVEDAIGRYG
HTRIATECADGDNQAACGNIDRDSLGNIVDLRNYLQNAGTYEVEGVDFFTAYRFPESSFGTFKASLDLAYVINNKSDGED
RAGIQFGDGGFPKLKGNLNIDWVMGDWDAHWKTRYVGAMDNDYVETYGFTAAKNGITERFDSYMVHNVSVGYNFDSYNTK
VAVGINNLFAKEPQWEAPDNGLAISTNNFSVTEYDVNMDRFVYLRATTKF

Sequences:

>Translated_930_residues
MHRNNILTHSIRTALISGVAVVAFTTPVAFAAEDGAKVERIEVTGSRIKRTDMESASPVLSMNRDEIEATGMISIGDILQ
TIPAAGSALNTAFNNGGNGSTNMDLRNLGSQRLLVLVNGKRWISSLGSTVDLNTIPTSAIERIDVLKDGASAVYGSDAIA
GVVNIITRKNFEGVEVSVYGGQNSKYDDGRQYTADITFGSVSEKGGLLFNMSHVTQQPIWAGDRDISATGYSSTADNTRL
KVKGSQFNQANQDALAAVGTANSSGIYDFMSKEGTGVNVGVDQLRPRTGSDVYNFAPDNYLSTPQNRNSFYVQGFYDISD
DLRFVSDFMMTNRKSSQELAPMPLTLGASFGEAASRVDIGANNIYNPFGEKLYGSNARAVANGEAAGYVPYALQRRMIEA
GSRQYNQNDTTYRAMVGLEGNIGDNWTWSATYIYGQNNQDILTTGLLNLTRINQALGDDCNAANGCVALNLFGGPGTITE
DMVDYITFDSVSRSGLTMKDYAFNISGDLFDLPAGAVGIAIGLERREESGFDTPDPLTVTGESSGNQRDATAGGFRLDEA
YTELSIPILENLLLTPAIRVSDHDAYGNSTTGKVGLEFRPMDDMLLRGTWAQGYRAPSISDLYAGNADSYPTWTDPCNTR
DDKGNPVDISGKPGCAAVPDGYRQANTQIRISQVSSPDLKPETSESYTFGTVYNPSWLEGAELTLDYYNIKVEDAIGRYG
HTRIATECADGDNQAACGNIDRDSLGNIVDLRNYLQNAGTYEVEGVDFFTAYRFPESSFGTFKASLDLAYVINNKSDGED
RAGIQFGDGGFPKLKGNLNIDWVMGDWDAHWKTRYVGAMDNDYVETYGFTAAKNGITERFDSYMVHNVSVGYNFDSYNTK
VAVGINNLFAKEPQWEAPDNGLAISTNNFSVTEYDVNMDRFVYLRATTKF
>Mature_930_residues
MHRNNILTHSIRTALISGVAVVAFTTPVAFAAEDGAKVERIEVTGSRIKRTDMESASPVLSMNRDEIEATGMISIGDILQ
TIPAAGSALNTAFNNGGNGSTNMDLRNLGSQRLLVLVNGKRWISSLGSTVDLNTIPTSAIERIDVLKDGASAVYGSDAIA
GVVNIITRKNFEGVEVSVYGGQNSKYDDGRQYTADITFGSVSEKGGLLFNMSHVTQQPIWAGDRDISATGYSSTADNTRL
KVKGSQFNQANQDALAAVGTANSSGIYDFMSKEGTGVNVGVDQLRPRTGSDVYNFAPDNYLSTPQNRNSFYVQGFYDISD
DLRFVSDFMMTNRKSSQELAPMPLTLGASFGEAASRVDIGANNIYNPFGEKLYGSNARAVANGEAAGYVPYALQRRMIEA
GSRQYNQNDTTYRAMVGLEGNIGDNWTWSATYIYGQNNQDILTTGLLNLTRINQALGDDCNAANGCVALNLFGGPGTITE
DMVDYITFDSVSRSGLTMKDYAFNISGDLFDLPAGAVGIAIGLERREESGFDTPDPLTVTGESSGNQRDATAGGFRLDEA
YTELSIPILENLLLTPAIRVSDHDAYGNSTTGKVGLEFRPMDDMLLRGTWAQGYRAPSISDLYAGNADSYPTWTDPCNTR
DDKGNPVDISGKPGCAAVPDGYRQANTQIRISQVSSPDLKPETSESYTFGTVYNPSWLEGAELTLDYYNIKVEDAIGRYG
HTRIATECADGDNQAACGNIDRDSLGNIVDLRNYLQNAGTYEVEGVDFFTAYRFPESSFGTFKASLDLAYVINNKSDGED
RAGIQFGDGGFPKLKGNLNIDWVMGDWDAHWKTRYVGAMDNDYVETYGFTAAKNGITERFDSYMVHNVSVGYNFDSYNTK
VAVGINNLFAKEPQWEAPDNGLAISTNNFSVTEYDVNMDRFVYLRATTKF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=175, Percent_Identity=29.7142857142857, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788478, Length=164, Percent_Identity=29.8780487804878, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 101051; Mature: 101051

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRNNILTHSIRTALISGVAVVAFTTPVAFAAEDGAKVERIEVTGSRIKRTDMESASPVL
CCCCCCHHHHHHHHHHCCEEEEEEECCEEEEECCCCEEEEEEECCCHHHHCCCCCCCCEE
SMNRDEIEATGMISIGDILQTIPAAGSALNTAFNNGGNGSTNMDLRNLGSQRLLVLVNGK
ECCCCCCCEECEEEHHHHHHHHCCCCCHHHHHHCCCCCCCCCCHHHHCCCCEEEEEECCH
RWISSLGSTVDLNTIPTSAIERIDVLKDGASAVYGSDAIAGVVNIITRKNFEGVEVSVYG
HHHHHCCCEEEECCCCHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHCCCCCCEEEEEEC
GQNSKYDDGRQYTADITFGSVSEKGGLLFNMSHVTQQPIWAGDRDISATGYSSTADNTRL
CCCCCCCCCCEEEEEEEECCCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCEE
KVKGSQFNQANQDALAAVGTANSSGIYDFMSKEGTGVNVGVDQLRPRTGSDVYNFAPDNY
EEECCCCCCCCCCCEEEEECCCCCCCHHHHCCCCCCEECCHHHCCCCCCCCCEECCCCCC
LSTPQNRNSFYVQGFYDISDDLRFVSDFMMTNRKSSQELAPMPLTLGASFGEAASRVDIG
CCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHEEECC
ANNIYNPFGEKLYGSNARAVANGEAAGYVPYALQRRMIEAGSRQYNQNDTTYRAMVGLEG
CCCCCCCHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEECC
NIGDNWTWSATYIYGQNNQDILTTGLLNLTRINQALGDDCNAANGCVALNLFGGPGTITE
CCCCCEEEEEEEEEECCCCCEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHH
DMVDYITFDSVSRSGLTMKDYAFNISGDLFDLPAGAVGIAIGLERREESGFDTPDPLTVT
HHHHHHHHCCCCCCCCEEEHEEEECCCCEEECCCCCEEEEEEEEHHHHCCCCCCCCEEEE
GESSGNQRDATAGGFRLDEAYTELSIPILENLLLTPAIRVSDHDAYGNSTTGKVGLEFRP
CCCCCCCCCCCCCCEEECHHHHHCCHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEEEEC
MDDMLLRGTWAQGYRAPSISDLYAGNADSYPTWTDPCNTRDDKGNPVDISGKPGCAAVPD
CHHHHEECCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCC
GYRQANTQIRISQVSSPDLKPETSESYTFGTVYNPSWLEGAELTLDYYNIKVEDAIGRYG
CHHHCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEEHHHHCCCC
HTRIATECADGDNQAACGNIDRDSLGNIVDLRNYLQNAGTYEVEGVDFFTAYRFPESSFG
CCEEEEECCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCC
TFKASLDLAYVINNKSDGEDRAGIQFGDGGFPKLKGNLNIDWVMGDWDAHWKTRYVGAMD
EEEEEEEEEEEECCCCCCCCCCCEEECCCCCCEEECCEEEEEEECCCCCCCEEEEECCCC
NDYVETYGFTAAKNGITERFDSYMVHNVSVGYNFDSYNTKVAVGINNLFAKEPQWEAPDN
CCCHHHCCCHHHHCCHHHHHHCEEEEEEEEEECCCCCCCEEEEEEHHHHCCCCCCCCCCC
GLAISTNNFSVTEYDVNMDRFVYLRATTKF
CEEEECCCEEEEEEECCCCEEEEEEEECCC
>Mature Secondary Structure
MHRNNILTHSIRTALISGVAVVAFTTPVAFAAEDGAKVERIEVTGSRIKRTDMESASPVL
CCCCCCHHHHHHHHHHCCEEEEEEECCEEEEECCCCEEEEEEECCCHHHHCCCCCCCCEE
SMNRDEIEATGMISIGDILQTIPAAGSALNTAFNNGGNGSTNMDLRNLGSQRLLVLVNGK
ECCCCCCCEECEEEHHHHHHHHCCCCCHHHHHHCCCCCCCCCCHHHHCCCCEEEEEECCH
RWISSLGSTVDLNTIPTSAIERIDVLKDGASAVYGSDAIAGVVNIITRKNFEGVEVSVYG
HHHHHCCCEEEECCCCHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHCCCCCCEEEEEEC
GQNSKYDDGRQYTADITFGSVSEKGGLLFNMSHVTQQPIWAGDRDISATGYSSTADNTRL
CCCCCCCCCCEEEEEEEECCCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCEE
KVKGSQFNQANQDALAAVGTANSSGIYDFMSKEGTGVNVGVDQLRPRTGSDVYNFAPDNY
EEECCCCCCCCCCCEEEEECCCCCCCHHHHCCCCCCEECCHHHCCCCCCCCCEECCCCCC
LSTPQNRNSFYVQGFYDISDDLRFVSDFMMTNRKSSQELAPMPLTLGASFGEAASRVDIG
CCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHEEECC
ANNIYNPFGEKLYGSNARAVANGEAAGYVPYALQRRMIEAGSRQYNQNDTTYRAMVGLEG
CCCCCCCHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEECC
NIGDNWTWSATYIYGQNNQDILTTGLLNLTRINQALGDDCNAANGCVALNLFGGPGTITE
CCCCCEEEEEEEEEECCCCCEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHH
DMVDYITFDSVSRSGLTMKDYAFNISGDLFDLPAGAVGIAIGLERREESGFDTPDPLTVT
HHHHHHHHCCCCCCCCEEEHEEEECCCCEEECCCCCEEEEEEEEHHHHCCCCCCCCEEEE
GESSGNQRDATAGGFRLDEAYTELSIPILENLLLTPAIRVSDHDAYGNSTTGKVGLEFRP
CCCCCCCCCCCCCCEEECHHHHHCCHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEEEEC
MDDMLLRGTWAQGYRAPSISDLYAGNADSYPTWTDPCNTRDDKGNPVDISGKPGCAAVPD
CHHHHEECCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCC
GYRQANTQIRISQVSSPDLKPETSESYTFGTVYNPSWLEGAELTLDYYNIKVEDAIGRYG
CHHHCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEEHHHHCCCC
HTRIATECADGDNQAACGNIDRDSLGNIVDLRNYLQNAGTYEVEGVDFFTAYRFPESSFG
CCEEEEECCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCC
TFKASLDLAYVINNKSDGEDRAGIQFGDGGFPKLKGNLNIDWVMGDWDAHWKTRYVGAMD
EEEEEEEEEEEECCCCCCCCCCCEEECCCCCCEEECCEEEEEEECCCCCCCEEEEECCCC
NDYVETYGFTAAKNGITERFDSYMVHNVSVGYNFDSYNTKVAVGINNLFAKEPQWEAPDN
CCCHHHCCCHHHHCCHHHHHHCEEEEEEEEEECCCCCCCEEEEEEHHHHCCCCCCCCCCC
GLAISTNNFSVTEYDVNMDRFVYLRATTKF
CEEEECCCEEEEEEECCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA