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The map label for this gene is clpX

Identifier: 160874745

GI number: 160874745

Start: 1967212

End: 1968492

Strand: Direct

Name: clpX

Synonym: Sbal195_1628

Alternate gene names: 160874745

Gene position: 1967212-1968492 (Clockwise)

Preceding gene: 160874744

Following gene: 160874746

Centisome position: 36.79

GC content: 46.6

Gene sequence:

>1281_bases
ATGGGCGACAACAAAAATAATGGTGACAGCGGTAAATTGCTGTACTGCTCTTTTTGCGGAAAGAGCCAGCATGAAGTCAG
AAAACTCATTGCTGGCCCATCAGTGTATGTATGCGACGAATGTGTTGAGTTATGTAACGACATCATTCGCGAAGAGATTA
AAGAAATCTCTCCAAAGCGCGATAGCGATAAGTTACCGACACCACATGAGTTGCGTGCACATTTAGACGATTATGTGATT
GGCCAAGACAGGGCGAAGAAAGTGCTATCTGTGGCAGTGTATAATCACTATAAGCGTTTGAAAAATGCGTCGCCTAAAGA
TGGTATCGAGCTGGGTAAGAGTAACATTTTGCTTATCGGTCCAACGGGTAGCGGTAAGACGCTGTTAGCTGAAACCCTTG
CGCGTTCACTCAATGTACCTTTCACTATGGCCGATGCCACGACACTGACTGAAGCGGGTTATGTGGGTGAAGACGTTGAA
AACATCATTCAAAAGTTGCTGCAAAAGTGCGACTACGATGTAGAGAAAGCGCAGCGTGGTATCGTTTATATCGATGAAAT
CGATAAAATTAGCCGTAAGTCAGACAATCCATCGATCACCCGTGACGTATCGGGTGAGGGCGTGCAGCAAGCGCTGCTTA
AGCTGATTGAAGGTACTGTTGCCGCGGTTCCACCACAAGGTGGCCGTAAGCATCCACAGCAAGAATTCTTACAAGTCGAT
ACTTCTAAGATCCTGTTTATCTGTGGCGGTGCGTTTGCAGGGCTTGAGAAAGTGATTGAGCAACGTGCACACGTTGGTTC
GGGTATCGGTTTCGGTGCTCAGGTAAAAGGCGAAAAAGAGAAGGCGACGATTTCTGAAACCTTAACTCAAGTTGAACCTG
GCGATTTGGTCAAATATGGCTTAATTCCTGAGTTCATCGGCCGTCTGCCTGTGGTTGCGACTCTGACTGAGCTGGATGAA
GAAGCCCTAGTGCAAATTTTATCTCAACCTAAAAATGCCCTGACTAAGCAGTACAGTGCGTTATTTGAGATGGAAGGCGT
CGAGCTTGAGTTCCGCGAAGATGCACTTAAAGCGATAGCACACAAGGCGATGTCACGTAAGACAGGTGCCCGTGGTTTAC
GCTCAATCGTTGAAAGTATTCTACTGGATACTATGTACGATATTCCTTCAGTCGATGGTGTTGTGAAGGCCGTTGTCGAT
GAATCAGTGGTGAAAGGTGAATCTGCACCTATCCTGATTTATGAGCACAATGAAGCCCAAGCAGCCTCTGGCGAGCAATA
A

Upstream 100 bases:

>100_bases
GACGAAACGCGGCTGATTTTTGCTTTTGACTGAGCTATGCTCTGTAAAGGTTAAGCAAATTTAAGACAGGCAGTAGAGCA
GACTGCAAATGAGGTAATTA

Downstream 100 bases:

>100_bases
TTGTACTGATTGCTAATAAACTGAAAAACAAGGAGTCCAATGGACTCCTTTTTTCGTATTAGCCATTGAAACTCAATAAA
GCGTCCCAATATACTCCAGT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MGDNKNNGDSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKRDSDKLPTPHELRAHLDDYVI
GQDRAKKVLSVAVYNHYKRLKNASPKDGIELGKSNILLIGPTGSGKTLLAETLARSLNVPFTMADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVD
TSKILFICGGAFAGLEKVIEQRAHVGSGIGFGAQVKGEKEKATISETLTQVEPGDLVKYGLIPEFIGRLPVVATLTELDE
EALVQILSQPKNALTKQYSALFEMEGVELEFREDALKAIAHKAMSRKTGARGLRSIVESILLDTMYDIPSVDGVVKAVVD
ESVVKGESAPILIYEHNEAQAASGEQ

Sequences:

>Translated_426_residues
MGDNKNNGDSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKRDSDKLPTPHELRAHLDDYVI
GQDRAKKVLSVAVYNHYKRLKNASPKDGIELGKSNILLIGPTGSGKTLLAETLARSLNVPFTMADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVD
TSKILFICGGAFAGLEKVIEQRAHVGSGIGFGAQVKGEKEKATISETLTQVEPGDLVKYGLIPEFIGRLPVVATLTELDE
EALVQILSQPKNALTKQYSALFEMEGVELEFREDALKAIAHKAMSRKTGARGLRSIVESILLDTMYDIPSVDGVVKAVVD
ESVVKGESAPILIYEHNEAQAASGEQ
>Mature_425_residues
GDNKNNGDSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKRDSDKLPTPHELRAHLDDYVIG
QDRAKKVLSVAVYNHYKRLKNASPKDGIELGKSNILLIGPTGSGKTLLAETLARSLNVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLEKVIEQRAHVGSGIGFGAQVKGEKEKATISETLTQVEPGDLVKYGLIPEFIGRLPVVATLTELDEE
ALVQILSQPKNALTKQYSALFEMEGVELEFREDALKAIAHKAMSRKTGARGLRSIVESILLDTMYDIPSVDGVVKAVVDE
SVVKGESAPILIYEHNEAQAASGEQ

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=329, Percent_Identity=51.9756838905775, Blast_Score=310, Evalue=1e-84,
Organism=Escherichia coli, GI1786642, Length=425, Percent_Identity=80.9411764705882, Blast_Score=710, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=101, Percent_Identity=44.5544554455446, Blast_Score=92, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=43.5897435897436, Blast_Score=261, Evalue=7e-70,
Organism=Caenorhabditis elegans, GI71982905, Length=312, Percent_Identity=43.5897435897436, Blast_Score=260, Evalue=9e-70,
Organism=Caenorhabditis elegans, GI71988663, Length=414, Percent_Identity=38.1642512077295, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI71988660, Length=256, Percent_Identity=40.625, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6319704, Length=425, Percent_Identity=40.2352941176471, Blast_Score=273, Evalue=4e-74,
Organism=Drosophila melanogaster, GI24648289, Length=333, Percent_Identity=47.1471471471471, Blast_Score=288, Evalue=4e-78,
Organism=Drosophila melanogaster, GI24648291, Length=333, Percent_Identity=47.1471471471471, Blast_Score=288, Evalue=4e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_SHEB2 (B8E5E8)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002358660.1
- ProteinModelPortal:   B8E5E8
- GeneID:   7087128
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_2749
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46432; Mature: 46300

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDNKNNGDSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKR
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
DSDKLPTPHELRAHLDDYVIGQDRAKKVLSVAVYNHYKRLKNASPKDGIELGKSNILLIG
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEE
PTGSGKTLLAETLARSLNVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRG
CCCCCHHHHHHHHHHHCCCCEEECCCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCC
IVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVD
EEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHC
TSKILFICGGAFAGLEKVIEQRAHVGSGIGFGAQVKGEKEKATISETLTQVEPGDLVKYG
CCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHC
LIPEFIGRLPVVATLTELDEEALVQILSQPKNALTKQYSALFEMEGVELEFREDALKAIA
CCHHHHCCCCHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
HKAMSRKTGARGLRSIVESILLDTMYDIPSVDGVVKAVVDESVVKGESAPILIYEHNEAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
AASGEQ
CCCCCC
>Mature Secondary Structure 
GDNKNNGDSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKR
CCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
DSDKLPTPHELRAHLDDYVIGQDRAKKVLSVAVYNHYKRLKNASPKDGIELGKSNILLIG
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEE
PTGSGKTLLAETLARSLNVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRG
CCCCCHHHHHHHHHHHCCCCEEECCCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCC
IVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVD
EEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHC
TSKILFICGGAFAGLEKVIEQRAHVGSGIGFGAQVKGEKEKATISETLTQVEPGDLVKYG
CCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHC
LIPEFIGRLPVVATLTELDEEALVQILSQPKNALTKQYSALFEMEGVELEFREDALKAIA
CCHHHHCCCCHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
HKAMSRKTGARGLRSIVESILLDTMYDIPSVDGVVKAVVDESVVKGESAPILIYEHNEAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
AASGEQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA