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The map label for this gene is leuO [H]

Identifier: 160874577

GI number: 160874577

Start: 1763045

End: 1763986

Strand: Direct

Name: leuO [H]

Synonym: Sbal195_1460

Alternate gene names: 160874577

Gene position: 1763045-1763986 (Clockwise)

Preceding gene: 160874575

Following gene: 160874579

Centisome position: 32.97

GC content: 47.88

Gene sequence:

>942_bases
ATGCCGACACAAAAGCCATTAGATTTAAACTTATTGCGGGTGTTTATGGTGGTTTACCGTACTCGTTCATTCACGCAAGC
GGCTGAAGAGTTGGACTTAACTCAGTCTTCGGTCAGTAACGCGATCAGTCGATTCAGGGTATGGGTCGGGGAGTCACTGT
TTAATCGGGTTGGGCGGGGAATTGAGCCGACGGCGGTGGCGCGGGAAATGTACCGTAAGTTTGAGCAGCCAATGGCAGAT
ATCGAAACTGTATTGCTGGGGTTTGAGCATTTTGATCCAAAGTGCAGTCAGCGACGCTTCTATGTGTATGCCAATGAGTC
GGTTATCGAAGCGCTGCAAACCGGTGTGCAGGCTTTATTACAGGATGCGGATATTGAAGTGATTTTTCGGGAATCACCGC
CACAGGAAGCTGATTTATATCGCGATATCTTGCTTGAGCGAGTCGCTGTGGCGATAGACATTAAACCCGCGCAGCAAAGT
TTGCTCTCGAGCAAATTACTCTTCACCGAAACCTTAGTGTGTATCGTCAGTCGGCAGCATCCTCGGATTCAAGGCGCCAT
TACCCATGAGCAGTATTTTGAGGAGAAACACGTCTTTTTGAATATGCGGCGTTTTAATCTTACTGCGGGGGATTTGTTTA
CCGAAGGCGTCTTGCCTAGACGCAAGATGTATAGTGAGCAGTCATCTTTATTGAGTATGTTTGCTACCGTAGGCAAAAGT
GAGGCGATAGGCATAGCGCCTTTGCGGTACGCCAGTCAGTACGCCGAGTTGTTCGGCATCCAGATTTTACCTATGCCACT
GAAAACAAGACCCATTGATTTGTATATGGTGTGGAGCAGTAAATACACCCAAAACCCGAGCCATCAATGGCTGCGAAGCT
TATTGCTCGATGCCAGTGCGAGCACTGTAAATGAAAAAGCTCTGAATCTTGCAAGCAGTTAG

Upstream 100 bases:

>100_bases
ATAGTGTCGTTGATGGTTTGAGTATAGACAGCTTGTGTATTTAGATAACTCGCGTTAGCTTGGGTTGTAATATTCATATT
GTGAATGAGTGGTTTCCCTT

Downstream 100 bases:

>100_bases
GCTAGCGATTCAGAGCTTAGTTTCGGTATGTAACCTTGGTTTTTGCTCAGTTCTAAACCTTAGTTCGTAATCTGATACTC
GAACGAACGTTAATTACTGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MPTQKPLDLNLLRVFMVVYRTRSFTQAAEELDLTQSSVSNAISRFRVWVGESLFNRVGRGIEPTAVAREMYRKFEQPMAD
IETVLLGFEHFDPKCSQRRFYVYANESVIEALQTGVQALLQDADIEVIFRESPPQEADLYRDILLERVAVAIDIKPAQQS
LLSSKLLFTETLVCIVSRQHPRIQGAITHEQYFEEKHVFLNMRRFNLTAGDLFTEGVLPRRKMYSEQSSLLSMFATVGKS
EAIGIAPLRYASQYAELFGIQILPMPLKTRPIDLYMVWSSKYTQNPSHQWLRSLLLDASASTVNEKALNLASS

Sequences:

>Translated_313_residues
MPTQKPLDLNLLRVFMVVYRTRSFTQAAEELDLTQSSVSNAISRFRVWVGESLFNRVGRGIEPTAVAREMYRKFEQPMAD
IETVLLGFEHFDPKCSQRRFYVYANESVIEALQTGVQALLQDADIEVIFRESPPQEADLYRDILLERVAVAIDIKPAQQS
LLSSKLLFTETLVCIVSRQHPRIQGAITHEQYFEEKHVFLNMRRFNLTAGDLFTEGVLPRRKMYSEQSSLLSMFATVGKS
EAIGIAPLRYASQYAELFGIQILPMPLKTRPIDLYMVWSSKYTQNPSHQWLRSLLLDASASTVNEKALNLASS
>Mature_312_residues
PTQKPLDLNLLRVFMVVYRTRSFTQAAEELDLTQSSVSNAISRFRVWVGESLFNRVGRGIEPTAVAREMYRKFEQPMADI
ETVLLGFEHFDPKCSQRRFYVYANESVIEALQTGVQALLQDADIEVIFRESPPQEADLYRDILLERVAVAIDIKPAQQSL
LSSKLLFTETLVCIVSRQHPRIQGAITHEQYFEEKHVFLNMRRFNLTAGDLFTEGVLPRRKMYSEQSSLLSMFATVGKSE
AIGIAPLRYASQYAELFGIQILPMPLKTRPIDLYMVWSSKYTQNPSHQWLRSLLLDASASTVNEKALNLASS

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=297, Percent_Identity=26.9360269360269, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1786820, Length=294, Percent_Identity=24.4897959183673, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI87081766, Length=285, Percent_Identity=23.5087719298246, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35736; Mature: 35604

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTQKPLDLNLLRVFMVVYRTRSFTQAAEELDLTQSSVSNAISRFRVWVGESLFNRVGRG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IEPTAVAREMYRKFEQPMADIETVLLGFEHFDPKCSQRRFYVYANESVIEALQTGVQALL
CCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHH
QDADIEVIFRESPPQEADLYRDILLERVAVAIDIKPAQQSLLSSKLLFTETLVCIVSRQH
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHCCCC
PRIQGAITHEQYFEEKHVFLNMRRFNLTAGDLFTEGVLPRRKMYSEQSSLLSMFATVGKS
CCCEEEECHHHHHHHHHHEEEEHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
EAIGIAPLRYASQYAELFGIQILPMPLKTRPIDLYMVWSSKYTQNPSHQWLRSLLLDASA
CCCCCHHHHHHHHHHHHHCCEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCH
STVNEKALNLASS
HHHHHHHHHCCCC
>Mature Secondary Structure 
PTQKPLDLNLLRVFMVVYRTRSFTQAAEELDLTQSSVSNAISRFRVWVGESLFNRVGRG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IEPTAVAREMYRKFEQPMADIETVLLGFEHFDPKCSQRRFYVYANESVIEALQTGVQALL
CCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHH
QDADIEVIFRESPPQEADLYRDILLERVAVAIDIKPAQQSLLSSKLLFTETLVCIVSRQH
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHCCCC
PRIQGAITHEQYFEEKHVFLNMRRFNLTAGDLFTEGVLPRRKMYSEQSSLLSMFATVGKS
CCCEEEECHHHHHHHHHHEEEEHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
EAIGIAPLRYASQYAELFGIQILPMPLKTRPIDLYMVWSSKYTQNPSHQWLRSLLLDASA
CCCCCHHHHHHHHHHHHHCCEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCH
STVNEKALNLASS
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609; 3519576 [H]