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The map label for this gene is cdr [H]

Identifier: 160874548

GI number: 160874548

Start: 1714200

End: 1715909

Strand: Direct

Name: cdr [H]

Synonym: Sbal195_1430

Alternate gene names: 160874548

Gene position: 1714200-1715909 (Clockwise)

Preceding gene: 160874547

Following gene: 160874549

Centisome position: 32.06

GC content: 45.44

Gene sequence:

>1710_bases
ATGACTAAAATAGTGATTGTAGGCGGTGTTGCTGGTGGCGCATCTGCAGCAGCAAGAGCAAGACGTGTATCAGAAACTGC
TGAAATTATCATGTTAGAGCGAGGCGAGTTTATTTCATTTGCGAACTGTGGCTTGCCTTATCATATTGGCGGTGAGATAG
AGTCTAGAGAGGCCTTGTTGCTGCAAACGCCTGAAAGCTTTAAATCACGTTTTAATATTGAAGTGCGCGTGTTTAATGAT
GTGATTGCAATTAATCGACAAACCAAGCAGTTAAGCATACGTAATCTGCTCACAGATGAAGTCTATCAAGAGTCATATGA
TAAGTTGTTGCTAAGTCCAGGTGCCTCGCCAATCAAACCTCCAATTAGCGGCATTAATAGTCATTTTGTGCATAGCCTGC
GAAATATTCCCGATATGGATAAGGTGTTAGCTAACCTTCTGCTGCATAAACCTAAGCATGCCACTGTCGTCGGTGGTGGC
TTTATTGGTTTAGAGATGGCAGAAGCACTACGACATCGAGGATTAGAGGTGAGTTTACTAGAGCTTGCCGACCAAGTGAT
GGGGCCGGTCGATGTTGAAATGGCCAATATACTGCATCAAAAATTAGTCGATAATGGCGTGGATTTACGTTTAAAAACAG
GATTGACCGCAGTTCATGAGCGTCCTATTCAACCGGCTGAATCCGACATTACCGATGACTACGATACGCCAGTGTTTCCT
CATTACCATCTACATTTAGATTTGAGTGATAACAGCAGCTTAGCTACAGATTTAGTGATCCTTGCCATAGGTGTTAAGCC
TGAAACCCGCTTAGCATCTGAATGTGGTTTAACCTTAGGCAAGCTCGGTGGAATTTACGTTGACGCCAGTATGCGCACTT
CTGACCCGGACATCTATGCCGTAGGCGATGCGATTGAAACTGATGATTTTGTTACAGGTAATCCAATACTTATTCCACTC
GCAGGTCCCGCCAATCGTCAAGGTCGATTAGCCGCAGATAATATGCTTGGCGGCAATAAGCTGTATCGCGCCACCCAAGG
TACTGCAATCTGTAAATTGTTTGATATGGCAATCGCCTCAACGGGGTTAAACGAGAAGAGTTTGCTAAGGCAAGTTATTC
CGTTTGAAAAGATTTATGTGCACACCGCTAGCCATGCCAGCTATTACCCTAGAGCACATCCCATTACCCTAAAGCTGTTG
TTTTGCCCTGATAACGGCCGTATTTTAGGGGCTCAAGCCGCTGGGATTGATGGCGTCGACAAACGCATTGATGTGTTAGC
AGTAGCACAACGGGCAGGAATGACAGTTTATGATTTAGCCGATCTTGAACTCACTTATGCACCACCCTTTGGCTCGGCGC
GTGATGTAGTGAATCAAGCCGGCATGGTGGCTGCAAACGTCTTATTAGGTGATGAATCCATTTGCCATTCTCAGGAACTA
GATCATCTGACGGCTGAACAAGTCATTATCGATGTGCGCAACCCGAGCGAGCTAACGGCAGTGGGTGCCATTGTTGGTGC
GATTAATATTCCGTTGCCAGTACTGAGAGACAGGCTCAATGAACTTCCTAAAGACAAAGAACTGCTCGTATTTTGCCAAG
TGGGTCTGCGCGGGCATGTCGCTTATCGGATGTTAGTGCAACATGGTTTTAAGGTACGCAACCTCAGTGGTGGCTATAAA
ACTTATCAAATGGTTAATGCACGTTTTTAG

Upstream 100 bases:

>100_bases
CCTTAATATTTATGGTCACTGTTTTGATTGTAAGCAAAAGCTTGAGAGCAAATCGGGTAGATAGACGAAATATTATTCGT
TAATTTTATTGGAGAAGAAC

Downstream 100 bases:

>100_bases
TGAATAACAGCATTAAAGATGGATTTTAAAACCATTTACATCCATCAATAAATAGGTGCAGCGTGAACAATTATCAAGAT
TGTAAACAAAGCCACAGCCA

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MTKIVIVGGVAGGASAAARARRVSETAEIIMLERGEFISFANCGLPYHIGGEIESREALLLQTPESFKSRFNIEVRVFND
VIAINRQTKQLSIRNLLTDEVYQESYDKLLLSPGASPIKPPISGINSHFVHSLRNIPDMDKVLANLLLHKPKHATVVGGG
FIGLEMAEALRHRGLEVSLLELADQVMGPVDVEMANILHQKLVDNGVDLRLKTGLTAVHERPIQPAESDITDDYDTPVFP
HYHLHLDLSDNSSLATDLVILAIGVKPETRLASECGLTLGKLGGIYVDASMRTSDPDIYAVGDAIETDDFVTGNPILIPL
AGPANRQGRLAADNMLGGNKLYRATQGTAICKLFDMAIASTGLNEKSLLRQVIPFEKIYVHTASHASYYPRAHPITLKLL
FCPDNGRILGAQAAGIDGVDKRIDVLAVAQRAGMTVYDLADLELTYAPPFGSARDVVNQAGMVAANVLLGDESICHSQEL
DHLTAEQVIIDVRNPSELTAVGAIVGAINIPLPVLRDRLNELPKDKELLVFCQVGLRGHVAYRMLVQHGFKVRNLSGGYK
TYQMVNARF

Sequences:

>Translated_569_residues
MTKIVIVGGVAGGASAAARARRVSETAEIIMLERGEFISFANCGLPYHIGGEIESREALLLQTPESFKSRFNIEVRVFND
VIAINRQTKQLSIRNLLTDEVYQESYDKLLLSPGASPIKPPISGINSHFVHSLRNIPDMDKVLANLLLHKPKHATVVGGG
FIGLEMAEALRHRGLEVSLLELADQVMGPVDVEMANILHQKLVDNGVDLRLKTGLTAVHERPIQPAESDITDDYDTPVFP
HYHLHLDLSDNSSLATDLVILAIGVKPETRLASECGLTLGKLGGIYVDASMRTSDPDIYAVGDAIETDDFVTGNPILIPL
AGPANRQGRLAADNMLGGNKLYRATQGTAICKLFDMAIASTGLNEKSLLRQVIPFEKIYVHTASHASYYPRAHPITLKLL
FCPDNGRILGAQAAGIDGVDKRIDVLAVAQRAGMTVYDLADLELTYAPPFGSARDVVNQAGMVAANVLLGDESICHSQEL
DHLTAEQVIIDVRNPSELTAVGAIVGAINIPLPVLRDRLNELPKDKELLVFCQVGLRGHVAYRMLVQHGFKVRNLSGGYK
TYQMVNARF
>Mature_568_residues
TKIVIVGGVAGGASAAARARRVSETAEIIMLERGEFISFANCGLPYHIGGEIESREALLLQTPESFKSRFNIEVRVFNDV
IAINRQTKQLSIRNLLTDEVYQESYDKLLLSPGASPIKPPISGINSHFVHSLRNIPDMDKVLANLLLHKPKHATVVGGGF
IGLEMAEALRHRGLEVSLLELADQVMGPVDVEMANILHQKLVDNGVDLRLKTGLTAVHERPIQPAESDITDDYDTPVFPH
YHLHLDLSDNSSLATDLVILAIGVKPETRLASECGLTLGKLGGIYVDASMRTSDPDIYAVGDAIETDDFVTGNPILIPLA
GPANRQGRLAADNMLGGNKLYRATQGTAICKLFDMAIASTGLNEKSLLRQVIPFEKIYVHTASHASYYPRAHPITLKLLF
CPDNGRILGAQAAGIDGVDKRIDVLAVAQRAGMTVYDLADLELTYAPPFGSARDVVNQAGMVAANVLLGDESICHSQELD
HLTAEQVIIDVRNPSELTAVGAIVGAINIPLPVLRDRLNELPKDKELLVFCQVGLRGHVAYRMLVQHGFKVRNLSGGYKT
YQMVNARF

Specific function: Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1789765, Length=352, Percent_Identity=27.2727272727273, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1789065, Length=375, Percent_Identity=25.0666666666667, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786307, Length=320, Percent_Identity=25.625, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1788892, Length=303, Percent_Identity=25.4125412541254, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=249, Percent_Identity=24.4979919678715, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24639257, Length=350, Percent_Identity=26.2857142857143, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281359715, Length=350, Percent_Identity=26.2857142857143, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281359713, Length=350, Percent_Identity=26.2857142857143, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639250, Length=350, Percent_Identity=26.2857142857143, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI18543267, Length=350, Percent_Identity=26.2857142857143, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639252, Length=350, Percent_Identity=26.2857142857143, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24585130, Length=346, Percent_Identity=23.4104046242775, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 61861; Mature: 61730

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIVIVGGVAGGASAAARARRVSETAEIIMLERGEFISFANCGLPYHIGGEIESREALL
CCEEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCEEEEECCCCCEEECCCCCCCCEEE
LQTPESFKSRFNIEVRVFNDVIAINRQTKQLSIRNLLTDEVYQESYDKLLLSPGASPIKP
EECCHHHHHCEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCC
PISGINSHFVHSLRNIPDMDKVLANLLLHKPKHATVVGGGFIGLEMAEALRHRGLEVSLL
CHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCEEEHH
ELADQVMGPVDVEMANILHQKLVDNGVDLRLKTGLTAVHERPIQPAESDITDDYDTPVFP
HHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCCCCCCCCCCCCCCCCCCC
HYHLHLDLSDNSSLATDLVILAIGVKPETRLASECGLTLGKLGGIYVDASMRTSDPDIYA
EEEEEEEECCCCCHHEEEEEEEECCCCCHHHHHHHCCCHHCCCCEEEECCCCCCCCCEEE
VGDAIETDDFVTGNPILIPLAGPANRQGRLAADNMLGGNKLYRATQGTAICKLFDMAIAS
ECCCCCCCCEECCCCEEEECCCCCCCCCCEEECCCCCCCCEEEECCCCHHHHHHHHHHHH
TGLNEKSLLRQVIPFEKIYVHTASHASYYPRAHPITLKLLFCPDNGRILGAQAAGIDGVD
CCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCH
KRIDVLAVAQRAGMTVYDLADLELTYAPPFGSARDVVNQAGMVAANVLLGDESICHSQEL
HHHHHHHHHHHCCCEEEEEECEEEEECCCCCCHHHHHHHCCCEEEEEEECCCHHHHHHHH
DHLTAEQVIIDVRNPSELTAVGAIVGAINIPLPVLRDRLNELPKDKELLVFCQVGLRGHV
CCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCHHH
AYRMLVQHGFKVRNLSGGYKTYQMVNARF
HHHHHHHCCCEEEECCCCCEEEEEEECCC
>Mature Secondary Structure 
TKIVIVGGVAGGASAAARARRVSETAEIIMLERGEFISFANCGLPYHIGGEIESREALL
CEEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCEEEEECCCCCEEECCCCCCCCEEE
LQTPESFKSRFNIEVRVFNDVIAINRQTKQLSIRNLLTDEVYQESYDKLLLSPGASPIKP
EECCHHHHHCEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCC
PISGINSHFVHSLRNIPDMDKVLANLLLHKPKHATVVGGGFIGLEMAEALRHRGLEVSLL
CHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCEEEHH
ELADQVMGPVDVEMANILHQKLVDNGVDLRLKTGLTAVHERPIQPAESDITDDYDTPVFP
HHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCCCCCCCCCCCCCCCCCCC
HYHLHLDLSDNSSLATDLVILAIGVKPETRLASECGLTLGKLGGIYVDASMRTSDPDIYA
EEEEEEEECCCCCHHEEEEEEEECCCCCHHHHHHHCCCHHCCCCEEEECCCCCCCCCEEE
VGDAIETDDFVTGNPILIPLAGPANRQGRLAADNMLGGNKLYRATQGTAICKLFDMAIAS
ECCCCCCCCEECCCCEEEECCCCCCCCCCEEECCCCCCCCEEEECCCCHHHHHHHHHHHH
TGLNEKSLLRQVIPFEKIYVHTASHASYYPRAHPITLKLLFCPDNGRILGAQAAGIDGVD
CCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCH
KRIDVLAVAQRAGMTVYDLADLELTYAPPFGSARDVVNQAGMVAANVLLGDESICHSQEL
HHHHHHHHHHHCCCEEEEEECEEEEECCCCCCHHHHHHHCCCEEEEEEECCCHHHHHHHH
DHLTAEQVIIDVRNPSELTAVGAIVGAINIPLPVLRDRLNELPKDKELLVFCQVGLRGHV
CCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCHHH
AYRMLVQHGFKVRNLSGGYKTYQMVNARF
HHHHHHHCCCEEEECCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA