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The map label for this gene is gstB [H]

Identifier: 160874535

GI number: 160874535

Start: 1700972

End: 1701598

Strand: Reverse

Name: gstB [H]

Synonym: Sbal195_1417

Alternate gene names: 160874535

Gene position: 1701598-1700972 (Counterclockwise)

Preceding gene: 160874537

Following gene: 160874534

Centisome position: 31.82

GC content: 44.5

Gene sequence:

>627_bases
ATGAAACTCTACGAATTAGCTCCGACTCCCAGCGCGCGTCGCGTCAGTATTTTTCTTGCGGAAAAAGGCATAGAAGTGCC
AAGAGTGAACGTCGATATCCGCGGAGGAGAAAATTTAAGTACCGAATTTAAAGCCAAAAGTGTAAATGGCCGCATTCCAT
TACTCGAACTCGATGATGGCAGCTACCTGTGTGAATCCGTTGCCATTTGCCGCTATTTAGAAGAAATCCACCCAAGTGCT
CACTCGCTGTTTGGTAATACGCCACTTGAGCGCGCAAAAGTAGAAATGTGGGAACGTATCATAGAGTTACAAGGCTTAAT
GGTTGGGTTTCAAGCCTTTCGTAATTTAAGCGGTGTCTATAAAGACAGGGAAAATTGTGTCGAGTCTTGGGGCGCAGAAT
CACGCCAAAGGGTCATTGACTTCCTACCAAGCTTAGACCAACAATTGAGCAAGTCGCCCTTTATGGCAGGCGATGAATTC
AGCATTGCCGATATTTCGGCTTACGTTTTTATCAGCTTTATTAAGAATTTAGATATTGAAGTCACTGACAACTTGCCGCA
TCTTAAAGCTTGGTTCATCACTATGGCGCAGCGTCCTGCCATAGTATCGTTAACCCCTAAAAAATAG

Upstream 100 bases:

>100_bases
GTTTAGATATGGCGTAAATTCTATCCTAACCGATCGTTCCGTTAAAGCCTTATATGCTCAAATCGAGCATAAAGCACAGA
TAAAAACTACAGGACTTTAG

Downstream 100 bases:

>100_bases
CGGCACAAATGCCTGAATAGGCACAAAAGTGAGTAGCTATAAGCGTTATAACCTAAAGGAATCATCATGATAGATTTATA
CACAGCCGCGACCCCTAACG

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST B1-1 [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKLYELAPTPSARRVSIFLAEKGIEVPRVNVDIRGGENLSTEFKAKSVNGRIPLLELDDGSYLCESVAICRYLEEIHPSA
HSLFGNTPLERAKVEMWERIIELQGLMVGFQAFRNLSGVYKDRENCVESWGAESRQRVIDFLPSLDQQLSKSPFMAGDEF
SIADISAYVFISFIKNLDIEVTDNLPHLKAWFITMAQRPAIVSLTPKK

Sequences:

>Translated_208_residues
MKLYELAPTPSARRVSIFLAEKGIEVPRVNVDIRGGENLSTEFKAKSVNGRIPLLELDDGSYLCESVAICRYLEEIHPSA
HSLFGNTPLERAKVEMWERIIELQGLMVGFQAFRNLSGVYKDRENCVESWGAESRQRVIDFLPSLDQQLSKSPFMAGDEF
SIADISAYVFISFIKNLDIEVTDNLPHLKAWFITMAQRPAIVSLTPKK
>Mature_208_residues
MKLYELAPTPSARRVSIFLAEKGIEVPRVNVDIRGGENLSTEFKAKSVNGRIPLLELDDGSYLCESVAICRYLEEIHPSA
HSLFGNTPLERAKVEMWERIIELQGLMVGFQAFRNLSGVYKDRENCVESWGAESRQRVIDFLPSLDQQLSKSPFMAGDEF
SIADISAYVFISFIKNLDIEVTDNLPHLKAWFITMAQRPAIVSLTPKK

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4758484, Length=207, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322968, Length=213, Percent_Identity=31.4553990610329, Blast_Score=108, Evalue=6e-25,
Organism=Drosophila melanogaster, GI20130115, Length=203, Percent_Identity=31.0344827586207, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19922532, Length=203, Percent_Identity=29.064039408867, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654983, Length=174, Percent_Identity=30.4597701149425, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 23496; Mature: 23496

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYELAPTPSARRVSIFLAEKGIEVPRVNVDIRGGENLSTEFKAKSVNGRIPLLELDDG
CCCEECCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCEEECCCCCCCEEEEECCC
SYLCESVAICRYLEEIHPSAHSLFGNTPLERAKVEMWERIIELQGLMVGFQAFRNLSGVY
HHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDRENCVESWGAESRQRVIDFLPSLDQQLSKSPFMAGDEFSIADISAYVFISFIKNLDIE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
VTDNLPHLKAWFITMAQRPAIVSLTPKK
EECCCCHHHHHHHHHHCCCEEEEECCCC
>Mature Secondary Structure
MKLYELAPTPSARRVSIFLAEKGIEVPRVNVDIRGGENLSTEFKAKSVNGRIPLLELDDG
CCCEECCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCEEECCCCCCCEEEEECCC
SYLCESVAICRYLEEIHPSAHSLFGNTPLERAKVEMWERIIELQGLMVGFQAFRNLSGVY
HHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDRENCVESWGAESRQRVIDFLPSLDQQLSKSPFMAGDEFSIADISAYVFISFIKNLDIE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
VTDNLPHLKAWFITMAQRPAIVSLTPKK
EECCCCHHHHHHHHHHCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8761466; 8436105; 2661269; 8645008; 9655824 [H]