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The map label for this gene is pheA [H]

Identifier: 160874416

GI number: 160874416

Start: 1535346

End: 1537340

Strand: Reverse

Name: pheA [H]

Synonym: Sbal195_1297

Alternate gene names: 160874416

Gene position: 1537340-1535346 (Counterclockwise)

Preceding gene: 160874417

Following gene: 160874404

Centisome position: 28.75

GC content: 46.62

Gene sequence:

>1995_bases
ATGCATACACCACAGCCTTTAAATCAAACCCGAGAGCAGATCACCAATCTGGATAATGAACTGCTGGCATTACTCGCTGA
GCGCCGTCGCTTAAGTCTAGAAGTGGCCCGTAGTAAAGAAGTGGATGTCAGACCCATCAGAGATACTCAAAGGGAAAAAG
AACTGCTCGCTAGACTGGTGAAAGAAGGCAGAGAAAAGGGATTAGATGCCCACTATGTTATCTCCCTTTACCAGAGCATC
ATTGAAGATTCAGTATTGAATCAACAAGCTTACCTTCACGGCCGTGCCAACCCAGAAACACAAAAACAGCAGTATTGTAT
CGCCTACCTAGGTGCACGAGGCTCTTACTCATATCTTGCAGCAACCCGCTATTGCCAACGCCGCCAAGTTGAAATGCTGG
ACTTAGGTTGCCAAAGTTTCGATGAAATAGTGCAAGCCGTTGAGTCTGGGCATGCTGATTATGGTTTCCTGCCGATTGAG
AACACTTCCTCGGGTTCAATCAACGAAGTCTACGATGTACTGCAGCACACCAGTCTATCGATCGTTGGTGAAACGACGAT
TGAAGTCAGCCATTGCCTACTAGGCAAAGCTGGCAGTAAATTAGCTGACATCAAAACTGTCTATGCCCACCCTCAGCCTA
TTAGCCAATGCAGCAGATATTTAAGTCAGCACAAAGACTTGAGACTGGAGTACTGCTCAAGCAGCGCAGAAGCGATGGAC
AAGGTGAATCAAAGCCCAGATAACAGCGCTGCAGCCATTGGTAGCGCCGAAGGTGGTGCACTCTATCAGCTAGAGTCTAT
AGAAGCGGGTTTAGCGAATCAGAAGATCAACCAAAGCCGCTTTATCGTTGTTGCCCGTAAAGCCGTCGCCGTGCCAGAGC
AGTTACCCGCTAAGACCACATTGATTATGGCGACGGGCCAAAAAGCCGGTGCATTAGTAGAAGCCCTGTTGGTTCTGAAA
GCGCATCAGTTAAACATGAGCAAATTAGAGTCACGCCCGATTCCAGGAACACCTTGGGAAGAGATGTTCTATTTGGATAT
CGACGCGAATATCTCCAGTGAATCTATGCAGGCCGGTTTAAAGCAACTCGAGCGGATCACCCGTTTTATCAAAGTATTAG
GCTGTTATCCTTGCGAAACAGTTAAGCCCACGCAACTGAGCAACAGCCAGTTACTGATTGAACCTAGCACCTCTAAGGAT
CAAGTCATCAGTGAGAATGGAGCAAATACCAGCCCTGTTCGATATAGCAAAGCCTATAAAGAGCAAGCTAGTGAGATCAA
CTGCGGTGCAATGACAATCGGTGCAGGGCATGTCGGTGCCATAGCGCAAATCACGCTGAATAATGACATTTCACACTTAG
CGTTATCGGCTTTCGAGCAGCAAGTGAAACAGCTTAAAGAAGTGGGATTCCAAGCGGTTCTGCTCAATAGCGTTAATCAA
GTGGCTATGGCGGAAGTGACCCTAGCTAAACTGCGCCAAATCCTGCATCAATATGGTCTAGTGTGCATTATTGCCATAGA
GCAAGAAGCCGATATGCCATTAGCCGTTCAGCACGCCGATATGCTGTTCTTGGCGGGTAAGCAGATGTTTAATCAAACCT
TACTCACTCAAGCGGGCACCTTACCAGTACCTTTAATACTTGAACGTAACGATATGGCAAATTTTGAAGAATTACTCACG
GCAACAGAAATTATCTTAAGCCAAGGCAATCAGCAACTTATTCTGTGTGACTCTGGCATTAGAACCTTAAATAACGCCAA
TCTACCCTCACTCGATTTGGCAAGCCTGATCCAGATTAAAGCCACGAGTCATTTGCCCATTTTGATCAACCCTAGCTATG
CCGTTTCGGATGATGCCCTGCTGGTTCAAACCCAAGGTATTAAGCAGCTTAAAGTGGATGGATTGATACTCAATTGCCCA
CTCGACAGCAATAATGACTCTGAGTCGCTTAACTTAATTAGCGCTGTAGTGCGGGAATTATATCGGGCGGTCTAA

Upstream 100 bases:

>100_bases
TTACTGTGTAAAAACGAAAGTAAAAATCCAAAGCCTCCCAACTGGGAGGCTTTTTTGTCTTAAACGATTGATAAAATACA
TGGCGGCAATTGAGGTCAGA

Downstream 100 bases:

>100_bases
ACTTTGATCTTGAGTGATTTAATTTAAAGTGAAATGGGGTTAGTTCGAAGTATATTCAGGGATAAAAGGCACTTATTTTA
TCCCTGATTGACTGAAATAA

Product: chorismate mutase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 664; Mature: 664

Protein sequence:

>664_residues
MHTPQPLNQTREQITNLDNELLALLAERRRLSLEVARSKEVDVRPIRDTQREKELLARLVKEGREKGLDAHYVISLYQSI
IEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLAATRYCQRRQVEMLDLGCQSFDEIVQAVESGHADYGFLPIE
NTSSGSINEVYDVLQHTSLSIVGETTIEVSHCLLGKAGSKLADIKTVYAHPQPISQCSRYLSQHKDLRLEYCSSSAEAMD
KVNQSPDNSAAAIGSAEGGALYQLESIEAGLANQKINQSRFIVVARKAVAVPEQLPAKTTLIMATGQKAGALVEALLVLK
AHQLNMSKLESRPIPGTPWEEMFYLDIDANISSESMQAGLKQLERITRFIKVLGCYPCETVKPTQLSNSQLLIEPSTSKD
QVISENGANTSPVRYSKAYKEQASEINCGAMTIGAGHVGAIAQITLNNDISHLALSAFEQQVKQLKEVGFQAVLLNSVNQ
VAMAEVTLAKLRQILHQYGLVCIIAIEQEADMPLAVQHADMLFLAGKQMFNQTLLTQAGTLPVPLILERNDMANFEELLT
ATEIILSQGNQQLILCDSGIRTLNNANLPSLDLASLIQIKATSHLPILINPSYAVSDDALLVQTQGIKQLKVDGLILNCP
LDSNNDSESLNLISAVVRELYRAV

Sequences:

>Translated_664_residues
MHTPQPLNQTREQITNLDNELLALLAERRRLSLEVARSKEVDVRPIRDTQREKELLARLVKEGREKGLDAHYVISLYQSI
IEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLAATRYCQRRQVEMLDLGCQSFDEIVQAVESGHADYGFLPIE
NTSSGSINEVYDVLQHTSLSIVGETTIEVSHCLLGKAGSKLADIKTVYAHPQPISQCSRYLSQHKDLRLEYCSSSAEAMD
KVNQSPDNSAAAIGSAEGGALYQLESIEAGLANQKINQSRFIVVARKAVAVPEQLPAKTTLIMATGQKAGALVEALLVLK
AHQLNMSKLESRPIPGTPWEEMFYLDIDANISSESMQAGLKQLERITRFIKVLGCYPCETVKPTQLSNSQLLIEPSTSKD
QVISENGANTSPVRYSKAYKEQASEINCGAMTIGAGHVGAIAQITLNNDISHLALSAFEQQVKQLKEVGFQAVLLNSVNQ
VAMAEVTLAKLRQILHQYGLVCIIAIEQEADMPLAVQHADMLFLAGKQMFNQTLLTQAGTLPVPLILERNDMANFEELLT
ATEIILSQGNQQLILCDSGIRTLNNANLPSLDLASLIQIKATSHLPILINPSYAVSDDALLVQTQGIKQLKVDGLILNCP
LDSNNDSESLNLISAVVRELYRAV
>Mature_664_residues
MHTPQPLNQTREQITNLDNELLALLAERRRLSLEVARSKEVDVRPIRDTQREKELLARLVKEGREKGLDAHYVISLYQSI
IEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLAATRYCQRRQVEMLDLGCQSFDEIVQAVESGHADYGFLPIE
NTSSGSINEVYDVLQHTSLSIVGETTIEVSHCLLGKAGSKLADIKTVYAHPQPISQCSRYLSQHKDLRLEYCSSSAEAMD
KVNQSPDNSAAAIGSAEGGALYQLESIEAGLANQKINQSRFIVVARKAVAVPEQLPAKTTLIMATGQKAGALVEALLVLK
AHQLNMSKLESRPIPGTPWEEMFYLDIDANISSESMQAGLKQLERITRFIKVLGCYPCETVKPTQLSNSQLLIEPSTSKD
QVISENGANTSPVRYSKAYKEQASEINCGAMTIGAGHVGAIAQITLNNDISHLALSAFEQQVKQLKEVGFQAVLLNSVNQ
VAMAEVTLAKLRQILHQYGLVCIIAIEQEADMPLAVQHADMLFLAGKQMFNQTLLTQAGTLPVPLILERNDMANFEELLT
ATEIILSQGNQQLILCDSGIRTLNNANLPSLDLASLIQIKATSHLPILINPSYAVSDDALLVQTQGIKQLKVDGLILNCP
LDSNNDSESLNLISAVVRELYRAV

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=386, Percent_Identity=54.6632124352332, Blast_Score=430, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6324013, Length=294, Percent_Identity=25.8503401360544, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 72948; Mature: 72948

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTPQPLNQTREQITNLDNELLALLAERRRLSLEVARSKEVDVRPIRDTQREKELLARLV
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHH
KEGREKGLDAHYVISLYQSIIEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLA
HHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHEEEEEECCCCCHHHHH
ATRYCQRRQVEMLDLGCQSFDEIVQAVESGHADYGFLPIENTSSGSINEVYDVLQHTSLS
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCEE
IVGETTIEVSHCLLGKAGSKLADIKTVYAHPQPISQCSRYLSQHKDLRLEYCSSSAEAMD
EEECCHHHHHHHHHCCCCCCHHHHHHEECCCCCHHHHHHHHHHCCCCCHHHHCCHHHHHH
KVNQSPDNSAAAIGSAEGGALYQLESIEAGLANQKINQSRFIVVARKAVAVPEQLPAKTT
HHCCCCCCCCEECCCCCCCCEEEEHHHHHCHHCCCCCCCEEEEEEHHHHCCCCCCCCCEE
LIMATGQKAGALVEALLVLKAHQLNMSKLESRPIPGTPWEEMFYLDIDANISSESMQAGL
EEEECCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHEEEEEECCCCCHHHHHHHH
KQLERITRFIKVLGCYPCETVKPTQLSNSQLLIEPSTSKDQVISENGANTSPVRYSKAYK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHCCCCCCCCCHHHHHHH
EQASEINCGAMTIGAGHVGAIAQITLNNDISHLALSAFEQQVKQLKEVGFQAVLLNSVNQ
HHHCCCCCCEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VAMAEVTLAKLRQILHQYGLVCIIAIEQEADMPLAVQHADMLFLAGKQMFNQTLLTQAGT
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCC
LPVPLILERNDMANFEELLTATEIILSQGNQQLILCDSGIRTLNNANLPSLDLASLIQIK
CCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHCCCCCCCCCCHHHHHHEE
ATSHLPILINPSYAVSDDALLVQTQGIKQLKVDGLILNCPLDSNNDSESLNLISAVVREL
ECCCCEEEECCCCEECCCEEEEEECCCCEEEECCEEEECCCCCCCCHHHHHHHHHHHHHH
YRAV
HHCC
>Mature Secondary Structure
MHTPQPLNQTREQITNLDNELLALLAERRRLSLEVARSKEVDVRPIRDTQREKELLARLV
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHH
KEGREKGLDAHYVISLYQSIIEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLA
HHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHEEEEEECCCCCHHHHH
ATRYCQRRQVEMLDLGCQSFDEIVQAVESGHADYGFLPIENTSSGSINEVYDVLQHTSLS
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCEE
IVGETTIEVSHCLLGKAGSKLADIKTVYAHPQPISQCSRYLSQHKDLRLEYCSSSAEAMD
EEECCHHHHHHHHHCCCCCCHHHHHHEECCCCCHHHHHHHHHHCCCCCHHHHCCHHHHHH
KVNQSPDNSAAAIGSAEGGALYQLESIEAGLANQKINQSRFIVVARKAVAVPEQLPAKTT
HHCCCCCCCCEECCCCCCCCEEEEHHHHHCHHCCCCCCCEEEEEEHHHHCCCCCCCCCEE
LIMATGQKAGALVEALLVLKAHQLNMSKLESRPIPGTPWEEMFYLDIDANISSESMQAGL
EEEECCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHEEEEEECCCCCHHHHHHHH
KQLERITRFIKVLGCYPCETVKPTQLSNSQLLIEPSTSKDQVISENGANTSPVRYSKAYK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHCCCCCCCCCHHHHHHH
EQASEINCGAMTIGAGHVGAIAQITLNNDISHLALSAFEQQVKQLKEVGFQAVLLNSVNQ
HHHCCCCCCEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VAMAEVTLAKLRQILHQYGLVCIIAIEQEADMPLAVQHADMLFLAGKQMFNQTLLTQAGT
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCC
LPVPLILERNDMANFEELLTATEIILSQGNQQLILCDSGIRTLNNANLPSLDLASLIQIK
CCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHCCCCCCCCCCHHHHHHEE
ATSHLPILINPSYAVSDDALLVQTQGIKQLKVDGLILNCPLDSNNDSESLNLISAVVREL
ECCCCEEEECCCCEECCCEEEEEECCCCEEEECCEEEECCCCCCCCHHHHHHHHHHHHHH
YRAV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]