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The map label for this gene is mtnN

Identifier: 160874372

GI number: 160874372

Start: 1488076

End: 1488786

Strand: Reverse

Name: mtnN

Synonym: Sbal195_1253

Alternate gene names: 160874372

Gene position: 1488786-1488076 (Counterclockwise)

Preceding gene: 160874373

Following gene: 160874371

Centisome position: 27.84

GC content: 48.52

Gene sequence:

>711_bases
ATGAAAATTGGAATTATTGGCGCAATGGAGCCAGAAGTCGCTCACCTGATCGCCGCCATGACAAATGCGACATCGCAAAC
TATTGCTGGTATTGAATTTATTGCTGGCACTCTTGCGGGTAAAGACGTTGTCGTAACTCGCTCTGGCATAGGTAAAGTGG
CCGCAAGTATTGCGACCACACTGCTCATCGAAAAATATGCGCCGGATGCAGTGATCAACACAGGTTCTGCCGGTGGTTTT
GTCGATACGCTGGCCATTGGCGATATCGTGATTTCTTCTGAAGTGCGTCACCACGATGTGGATGTCACCGCCTTTGGCTA
CGAAATTGGCCAAATGGCGCAGCAACCTGCTGCGTTTATCCCAGCCGCTCATTTAGTTGAAGCCGCCAACAAGGCCATTG
CTCAACTAGGCGAAGTCAAAGCGATTGAAGGGTTGATCTGTACTGGTGATAGCTTTATTTGCGATCCTGTTCGCACCCAA
GCCATGTTGAAAAACTTCCCAACGATGGCCGCCTGTGAAATGGAAGGCGCTGCAATCGCTCAAGTTTGTCATCAATTTGG
TGTGCCATTTGTGGTGATCCGCTCTTTATCGGATAACGCCAACAATGACTCGCCAGTGGATTTTGATTCTTATATTGTCA
AAGCGGGTTACCACTCAGCGCTGATGGTGATGCTGCTACTTGAGCAACTGAATCCTAGCGCAGTAAAATAA

Upstream 100 bases:

>100_bases
AGCAATCCCAATCTCACCATAACGACAGCACAAAACTGTGTGGTATATTAGCCAGCATTCTCGTGTCCCACTCTTAAGTG
TTGAATCAAAAAGGTCTCCC

Downstream 100 bases:

>100_bases
TCACTTAAGCGGAAAAGTACCGAATGCACACCTCTTTTTATCAACAACTTGTCGAGATAGATGGCGCTTTGTTTGAAGGC
TTTTTGGTACTTTTTTTTGC

Product: adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKIGIIGAMEPEVAHLIAAMTNATSQTIAGIEFIAGTLAGKDVVVTRSGIGKVAASIATTLLIEKYAPDAVINTGSAGGF
VDTLAIGDIVISSEVRHHDVDVTAFGYEIGQMAQQPAAFIPAAHLVEAANKAIAQLGEVKAIEGLICTGDSFICDPVRTQ
AMLKNFPTMAACEMEGAAIAQVCHQFGVPFVVIRSLSDNANNDSPVDFDSYIVKAGYHSALMVMLLLEQLNPSAVK

Sequences:

>Translated_236_residues
MKIGIIGAMEPEVAHLIAAMTNATSQTIAGIEFIAGTLAGKDVVVTRSGIGKVAASIATTLLIEKYAPDAVINTGSAGGF
VDTLAIGDIVISSEVRHHDVDVTAFGYEIGQMAQQPAAFIPAAHLVEAANKAIAQLGEVKAIEGLICTGDSFICDPVRTQ
AMLKNFPTMAACEMEGAAIAQVCHQFGVPFVVIRSLSDNANNDSPVDFDSYIVKAGYHSALMVMLLLEQLNPSAVK
>Mature_236_residues
MKIGIIGAMEPEVAHLIAAMTNATSQTIAGIEFIAGTLAGKDVVVTRSGIGKVAASIATTLLIEKYAPDAVINTGSAGGF
VDTLAIGDIVISSEVRHHDVDVTAFGYEIGQMAQQPAAFIPAAHLVEAANKAIAQLGEVKAIEGLICTGDSFICDPVRTQ
AMLKNFPTMAACEMEGAAIAQVCHQFGVPFVVIRSLSDNANNDSPVDFDSYIVKAGYHSALMVMLLLEQLNPSAVK

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily

Homologues:

Organism=Escherichia coli, GI1786354, Length=230, Percent_Identity=48.695652173913, Blast_Score=191, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNN_SHEB2 (B8EBS7)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002359045.1
- ProteinModelPortal:   B8EBS7
- SMR:   B8EBS7
- GeneID:   7087915
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_3137
- HOGENOM:   HBG367723
- OMA:   LEHFPTM
- ProtClustDB:   CLSK906203
- HAMAP:   MF_01684
- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR01704

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =3.2.2.9

Molecular weight: Translated: 24631; Mature: 24631

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: ACT_SITE 12-12 BINDING 78-78 BINDING 153-153 BINDING 198-198

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGIIGAMEPEVAHLIAAMTNATSQTIAGIEFIAGTLAGKDVVVTRSGIGKVAASIATT
CEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHH
LLIEKYAPDAVINTGSAGGFVDTLAIGDIVISSEVRHHDVDVTAFGYEIGQMAQQPAAFI
HHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCCCHHCCCCEEEHHHHHHHHHHCCHHHC
PAAHLVEAANKAIAQLGEVKAIEGLICTGDSFICDPVRTQAMLKNFPTMAACEMEGAAIA
CHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEECCHHHHHHHHHCCCCCEECCCCCHHHH
QVCHQFGVPFVVIRSLSDNANNDSPVDFDSYIVKAGYHSALMVMLLLEQLNPSAVK
HHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIGIIGAMEPEVAHLIAAMTNATSQTIAGIEFIAGTLAGKDVVVTRSGIGKVAASIATT
CEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHH
LLIEKYAPDAVINTGSAGGFVDTLAIGDIVISSEVRHHDVDVTAFGYEIGQMAQQPAAFI
HHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCCCHHCCCCEEEHHHHHHHHHHCCHHHC
PAAHLVEAANKAIAQLGEVKAIEGLICTGDSFICDPVRTQAMLKNFPTMAACEMEGAAIA
CHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEECCHHHHHHHHHCCCCCEECCCCCHHHH
QVCHQFGVPFVVIRSLSDNANNDSPVDFDSYIVKAGYHSALMVMLLLEQLNPSAVK
HHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA