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The map label for this gene is pgi [H]

Identifier: 160874264

GI number: 160874264

Start: 1354995

End: 1356632

Strand: Reverse

Name: pgi [H]

Synonym: Sbal195_1144

Alternate gene names: 160874264

Gene position: 1356632-1354995 (Counterclockwise)

Preceding gene: 160874265

Following gene: 160874263

Centisome position: 25.37

GC content: 46.58

Gene sequence:

>1638_bases
ATGACACTCTTGACCCAAAGCTCAACATGGCAAGCTTTATCAGCACACAGTAAAAATGTGCCGCATATGCGGGAATTGTT
TGCCACTGACGCGGCACGTTTCAATAAAATGTCGCTATCTGCCTGTGGTTTATTACTGGATTACTCTAAAAACAGAGCAA
CGGCGGAAACGCTTGATCTGTTATTTACGTTGGCAAGCAATAGTCAACTTGAAGCAAAAATCAAAGCGATGTTTGCTGGT
GAGATCATTAACACCACCGAGAAGCGCGCCGTTCTGCACACAGCGCTGCGTAGCACTGCGGAGCAGTCGATTATTGCCGA
GGGTCAAGACATAGTTCCTGAAGTTCAACAAACTCTGAATAAAATGCAAGGGTTTGTGAGCTCAGTGACGTCCGGTCAAT
GGAAAGGTTACACAGGTAAAGCGATAACCGATATTGTCAGTATCGGTATCGGTGGATCTTTCCTTGGTCCAAAAATTGTC
TCTCAGGCGCTGCGCCCGTATTGGAACCCAGAGTTGAAATGTCACTTTGTGGCAAACGTCGACGGTACTTCAATCAGTGA
GAAGCTGAAATTACTGGATCCTGAAACGACTCTGTTCATCATGTCGTCCAAGTCTTTTGGAACACAGGAAACCTTAACCA
ATACACTCACTGCTAGAGAATGGTTCTTAGCAAAAGGCGGTTTGCAGTCGGATGTGGCAAAACACTTTGTCGCAGTGACG
TCAAACGTCGCTAAAGCGACTGATTTTGGTATTGATGCAGACAACATTTTCCCAATGTGGGATTGGGTTGGCGGTCGTTA
CTCACTCTGGTCAGCGATTGGTTTACCGATAGCACTCTTGATTGGCATGGATAACTTCAGAGCCTTGCTCTCAGGTGCGC
ACCAAATGGATGAGCATTTCGCCAATGCGCCGCTGACAGAAAATATGCCAGTGATCATGGGCTTATTATCCCTATGGTAC
GGTAACTTCTTCAATGCTCAGTCCCATGTTGTACTGACATACGATCATTATCTGCGTGGTCTACCCGCTTACTTCCAGCA
GCTCGATATGGAAAGTAACGGTAAGTCTGTCACCTTAAACGGGACGGATGTTGACTACAGTACAGGTCCGGTGATTTGGG
GTGGCGAAGGTACTAATGGCCAACATGCCTACCACCAGCTGTTGCATCAAGGTACTGCACTGATCCCTGCCGATTTTATT
ATGCCACTGCAAAGTCATAATCCTATCGGTGAGCACCACGACCAATTAGCGTCAAACTGCTTTGGCCAGACTCAAGCCTT
AATGCAAGGTCGTACTTTTGATGAAGCCTTAGCCGAACTCGCTAATAGCGCATTACCTGCGGCTGAAAAGCAGTTGATCG
CAAAACATAAAGTGATGCCAGGTAACAAGCCGAGCAACACCTTACTCATGGATAAGCTCACGCCGAGCACCCTAGGTGCT
TTAATTGCCCTGTATGAACACAGAACCTTCGTTCAAGGTGCAATTTGGGACATTAACTCCTTCGATCAATGGGGTGTAGA
ACTCGGTAAGGATCTGGGTAACGATGTGTTAACACGCATAGGTGCAAGCCAGGATTGTGATGCCTTAGATGCCTCAAGTA
ACGCATTGATTAACCTTTATCGACATGGCAAAATCTAA

Upstream 100 bases:

>100_bases
AAGCTTGCGGAAGGTATTCGAAACTTTGCCATAGACCAAGGCAAACTCGAAGTGATGCTCACGGCTAAGCTCGCAAACTA
AGCATTCTGGAGACAGTGAG

Downstream 100 bases:

>100_bases
TCGAACAAAAAGCCAGCAATTGCTGGCTTTTTAATTTTATCCTTTTATTTTTATTCAACTTTTCGACTCTTCCTCGCTCT
CAACCCACACTTAAGATCAA

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MTLLTQSSTWQALSAHSKNVPHMRELFATDAARFNKMSLSACGLLLDYSKNRATAETLDLLFTLASNSQLEAKIKAMFAG
EIINTTEKRAVLHTALRSTAEQSIIAEGQDIVPEVQQTLNKMQGFVSSVTSGQWKGYTGKAITDIVSIGIGGSFLGPKIV
SQALRPYWNPELKCHFVANVDGTSISEKLKLLDPETTLFIMSSKSFGTQETLTNTLTAREWFLAKGGLQSDVAKHFVAVT
SNVAKATDFGIDADNIFPMWDWVGGRYSLWSAIGLPIALLIGMDNFRALLSGAHQMDEHFANAPLTENMPVIMGLLSLWY
GNFFNAQSHVVLTYDHYLRGLPAYFQQLDMESNGKSVTLNGTDVDYSTGPVIWGGEGTNGQHAYHQLLHQGTALIPADFI
MPLQSHNPIGEHHDQLASNCFGQTQALMQGRTFDEALAELANSALPAAEKQLIAKHKVMPGNKPSNTLLMDKLTPSTLGA
LIALYEHRTFVQGAIWDINSFDQWGVELGKDLGNDVLTRIGASQDCDALDASSNALINLYRHGKI

Sequences:

>Translated_545_residues
MTLLTQSSTWQALSAHSKNVPHMRELFATDAARFNKMSLSACGLLLDYSKNRATAETLDLLFTLASNSQLEAKIKAMFAG
EIINTTEKRAVLHTALRSTAEQSIIAEGQDIVPEVQQTLNKMQGFVSSVTSGQWKGYTGKAITDIVSIGIGGSFLGPKIV
SQALRPYWNPELKCHFVANVDGTSISEKLKLLDPETTLFIMSSKSFGTQETLTNTLTAREWFLAKGGLQSDVAKHFVAVT
SNVAKATDFGIDADNIFPMWDWVGGRYSLWSAIGLPIALLIGMDNFRALLSGAHQMDEHFANAPLTENMPVIMGLLSLWY
GNFFNAQSHVVLTYDHYLRGLPAYFQQLDMESNGKSVTLNGTDVDYSTGPVIWGGEGTNGQHAYHQLLHQGTALIPADFI
MPLQSHNPIGEHHDQLASNCFGQTQALMQGRTFDEALAELANSALPAAEKQLIAKHKVMPGNKPSNTLLMDKLTPSTLGA
LIALYEHRTFVQGAIWDINSFDQWGVELGKDLGNDVLTRIGASQDCDALDASSNALINLYRHGKI
>Mature_544_residues
TLLTQSSTWQALSAHSKNVPHMRELFATDAARFNKMSLSACGLLLDYSKNRATAETLDLLFTLASNSQLEAKIKAMFAGE
IINTTEKRAVLHTALRSTAEQSIIAEGQDIVPEVQQTLNKMQGFVSSVTSGQWKGYTGKAITDIVSIGIGGSFLGPKIVS
QALRPYWNPELKCHFVANVDGTSISEKLKLLDPETTLFIMSSKSFGTQETLTNTLTAREWFLAKGGLQSDVAKHFVAVTS
NVAKATDFGIDADNIFPMWDWVGGRYSLWSAIGLPIALLIGMDNFRALLSGAHQMDEHFANAPLTENMPVIMGLLSLWYG
NFFNAQSHVVLTYDHYLRGLPAYFQQLDMESNGKSVTLNGTDVDYSTGPVIWGGEGTNGQHAYHQLLHQGTALIPADFIM
PLQSHNPIGEHHDQLASNCFGQTQALMQGRTFDEALAELANSALPAAEKQLIAKHKVMPGNKPSNTLLMDKLTPSTLGAL
IALYEHRTFVQGAIWDINSFDQWGVELGKDLGNDVLTRIGASQDCDALDASSNALINLYRHGKI

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=553, Percent_Identity=50.2712477396022, Blast_Score=577, Evalue=1e-164,
Organism=Homo sapiens, GI296080693, Length=553, Percent_Identity=46.6546112115732, Blast_Score=520, Evalue=1e-147,
Organism=Escherichia coli, GI1790457, Length=540, Percent_Identity=52.5925925925926, Blast_Score=593, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI71996708, Length=549, Percent_Identity=51.9125683060109, Blast_Score=569, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI71996703, Length=549, Percent_Identity=51.9125683060109, Blast_Score=569, Evalue=1e-162,
Organism=Saccharomyces cerevisiae, GI6319673, Length=527, Percent_Identity=50.6641366223909, Blast_Score=531, Evalue=1e-152,
Organism=Drosophila melanogaster, GI24651916, Length=527, Percent_Identity=53.5104364326376, Blast_Score=578, Evalue=1e-165,
Organism=Drosophila melanogaster, GI24651914, Length=527, Percent_Identity=53.5104364326376, Blast_Score=578, Evalue=1e-165,
Organism=Drosophila melanogaster, GI17737445, Length=527, Percent_Identity=53.5104364326376, Blast_Score=578, Evalue=1e-165,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 59565; Mature: 59434

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLTQSSTWQALSAHSKNVPHMRELFATDAARFNKMSLSACGLLLDYSKNRATAETLDL
CCEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCCHHHHHHH
LFTLASNSQLEAKIKAMFAGEIINTTEKRAVLHTALRSTAEQSIIAEGQDIVPEVQQTLN
HHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KMQGFVSSVTSGQWKGYTGKAITDIVSIGIGGSFLGPKIVSQALRPYWNPELKCHFVANV
HHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEEEEEECC
DGTSISEKLKLLDPETTLFIMSSKSFGTQETLTNTLTAREWFLAKGGLQSDVAKHFVAVT
CCCCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SNVAKATDFGIDADNIFPMWDWVGGRYSLWSAIGLPIALLIGMDNFRALLSGAHQMDEHF
HHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ANAPLTENMPVIMGLLSLWYGNFFNAQSHVVLTYDHYLRGLPAYFQQLDMESNGKSVTLN
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEHHHHHCCHHHHHHHHCCCCCCCEEEEC
GTDVDYSTGPVIWGGEGTNGQHAYHQLLHQGTALIPADFIMPLQSHNPIGEHHDQLASNC
CCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHH
FGQTQALMQGRTFDEALAELANSALPAAEKQLIAKHKVMPGNKPSNTLLMDKLTPSTLGA
HHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHH
LIALYEHRTFVQGAIWDINSFDQWGVELGKDLGNDVLTRIGASQDCDALDASSNALINLY
HHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
RHGKI
ECCCC
>Mature Secondary Structure 
TLLTQSSTWQALSAHSKNVPHMRELFATDAARFNKMSLSACGLLLDYSKNRATAETLDL
CEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCCHHHHHHH
LFTLASNSQLEAKIKAMFAGEIINTTEKRAVLHTALRSTAEQSIIAEGQDIVPEVQQTLN
HHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KMQGFVSSVTSGQWKGYTGKAITDIVSIGIGGSFLGPKIVSQALRPYWNPELKCHFVANV
HHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEEEEEECC
DGTSISEKLKLLDPETTLFIMSSKSFGTQETLTNTLTAREWFLAKGGLQSDVAKHFVAVT
CCCCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SNVAKATDFGIDADNIFPMWDWVGGRYSLWSAIGLPIALLIGMDNFRALLSGAHQMDEHF
HHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ANAPLTENMPVIMGLLSLWYGNFFNAQSHVVLTYDHYLRGLPAYFQQLDMESNGKSVTLN
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEHHHHHCCHHHHHHHHCCCCCCCEEEEC
GTDVDYSTGPVIWGGEGTNGQHAYHQLLHQGTALIPADFIMPLQSHNPIGEHHDQLASNC
CCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHH
FGQTQALMQGRTFDEALAELANSALPAAEKQLIAKHKVMPGNKPSNTLLMDKLTPSTLGA
HHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHH
LIALYEHRTFVQGAIWDINSFDQWGVELGKDLGNDVLTRIGASQDCDALDASSNALINLY
HHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
RHGKI
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA